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Nasdaq · USD

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BeOne Medicines Ltd.

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2168
SEC CIK
0001651308
Parsed reports
543

Last 12 months

Inside the activity.

0 purchase rows · 204 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 2025017
Dec 2025026
Jan 202601
Feb 202602
Mar 202601
Apr 202601
May 202608
Jun 2026032
Jul 2026064
Aug 2026027
Sep 2026020
Oct 202605

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
November 18, 2019 Filed Nov 21, 2019 00:19 UTC
Huang JaneCMO, Hematology
Exercise / conversionShare Option (Right to Buy) · Derivative 19,500 $0.00 Strike: $2.27 $0.00
Disclosure

SEC source: 0001651308-19-000118 · wf-form4_157429554336283.xml · derivative · entry 8

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 597,575

Underlying: Ordinary Shares · 19,500 shares

Expires 2026-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

F7 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of September 2, 2016 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:19 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 100 $198.93 $19,893.00
Disclosure

SEC source: 0001651308-19-000118 · wf-form4_157429554336283.xml · nonDerivative · entry 7

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2018.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:19 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 95 $195.82 $18,602.90
Disclosure

SEC source: 0001651308-19-000118 · wf-form4_157429554336283.xml · nonDerivative · entry 6

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2018.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:19 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 605 $195.01 $117,983.35
Disclosure

SEC source: 0001651308-19-000118 · wf-form4_157429554336283.xml · nonDerivative · entry 5

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 195

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2018.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $194.53 to $195.43, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:19 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 500 $193.63 $96,813.00
Disclosure

SEC source: 0001651308-19-000118 · wf-form4_157429554336283.xml · nonDerivative · entry 4

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 800

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2018.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $193.31 to $193.85, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:19 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 200 $192.24 $38,448.00
Disclosure

SEC source: 0001651308-19-000118 · wf-form4_157429554336283.xml · nonDerivative · entry 3

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,300

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 11, 2018.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $191.90 to $192.58, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:19 UTC
Huang JaneCMO, Hematology
Exercise / conversionAmerican Depositary Shares 1,500 $29.49 $44,235.00
Disclosure

SEC source: 0001651308-19-000118 · wf-form4_157429554336283.xml · nonDerivative · entry 2

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 325,000 $0.00 Strike: $0.50 $0.00
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · derivative · entry 11

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,795,000

Underlying: Ordinary Shares · 325,000 shares

Expires 2025-07-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F9 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

F10 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on July 15, 2016, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon a sale event or certain termination events.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
SaleAmerican Depositary Shares 400 $198.93 $79,572.00
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 10

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 24, 2018.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
SaleAmerican Depositary Shares 200 $197.55 $39,510.00
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 9

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 400

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 24, 2018.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
SaleAmerican Depositary Shares 200 $196.63 $39,326.00
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 8

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 600

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 24, 2018.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $196.22 to $197.04, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
SaleAmerican Depositary Shares 5,633 $195.57 $1,101,671.16
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 7

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 800

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 24, 2018.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $195.14 to $196.12, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
SaleAmerican Depositary Shares 8,156 $194.62 $1,587,310.93
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 6

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,433

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 24, 2018.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $194.13 to $195.09, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
SaleAmerican Depositary Shares 6,944 $193.60 $1,344,334.10
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 5

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,589

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 24, 2018.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $193.12 to $194.09, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
SaleAmerican Depositary Shares 2,311 $192.63 $445,168.16
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 4

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,533

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 24, 2018.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $192.12 to $193.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
SaleAmerican Depositary Shares 1,156 $191.80 $221,723.69
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 3

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,844

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 24, 2018.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $191.09 to $192.03, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 18, 2019 Filed Nov 21, 2019 00:20 UTC
Liang HowardCFO & Chief Strategy Officer
Exercise / conversionAmerican Depositary Shares 25,000 $6.50 $162,500.00
Disclosure

SEC source: 0001651308-19-000119 · wf-form4_157429562436934.xml · nonDerivative · entry 2

Liang Howard · CIK 0001663427 · CFO & Chief Strategy Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share ("ADS") represents 13 Ordinary Shares.

Read SEC document
November 15, 2019 Filed Nov 18, 2019 22:22 UTC
Wu XiaobinPresident & GM China
SaleAmerican Depositary Shares 1,000 $202.05 $202,050.00
Disclosure

SEC source: 0001651308-19-000116 · wf-form4_157411574054527.xml · nonDerivative · entry 3

Wu Xiaobin · CIK 0001739452 · President & GM China

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 5, 2018.

Read SEC document
November 15, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 395 $202.05 $79,809.75
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 14

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 0

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

F3 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

Read SEC document
November 15, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 1,496 $202.05 $302,266.80
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 12

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

Read SEC document
November 14, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 2,605 $193.57 $504,241.77
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 13

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 395

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

F3 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

Read SEC document
November 14, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 100 $196.87 $19,687.00
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 11

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,496

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

Read SEC document
November 14, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 300 $195.86 $58,757.01
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 10

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,596

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $195.80 to $195.97, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 14, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 1,900 $195.14 $370,773.98
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 9

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,896

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $194.74 to $195.70, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 14, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 704 $194.12 $136,662.17
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 8

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,796

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $193.74 to 194.55, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 14, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 2,200 $193.04 $424,691.52
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 7

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,500

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $192.67 to $193.41, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 14, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 2,500 $192.19 $480,482.25
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 6

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,700

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $191.64 to $192.56, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 14, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 800 $191.03 $152,826.00
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 5

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,200

F5 · security: Each American Depositary Share represents 13 Ordinary Shares.

F6 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on August 23, 2019.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $190.50 to $191.42, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

Read SEC document
November 13, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
GrantOrdinary Shares 50 $0.00 $0.00
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 4

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 50

F4 · ownership.nature: These securities are held by the spouse of the Reporting Person.

Read SEC document
November 13, 2019 Filed Nov 18, 2019 22:24 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
OtherOrdinary Shares 50 $0.00 $0.00
Disclosure

SEC source: 0001651308-19-000117 · wf-form4_157411585017840.xml · nonDerivative · entry 3

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnote

Disclosed balance after: 4,903,998

F2 · kind: Pro rata distribution for no value from Wang Investment LLC which is exempt pursuant to Rule 16a-13 and Rule 16a-9.

F3 · ownership.nature: These securities are held by Wang Investment LLC, of which 99% of the limited liability company interest is owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

Read SEC document
November 05, 2019 Filed Nov 6, 2019 18:50 UTC Exercise / conversionShare Option (Right to Buy) · Derivative 52,000 $0.00 Strike: $3.16 $0.00
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · derivative · entry 13

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 65,988

Underlying: Ordinary Shares · 52,000 shares

Expires 2027-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

F12 · derivative.exercise_date: The option shall become exercisable in full upon the earlier to occur of the first anniversary of the grant date or the date of the next annual general meeting; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board or otherwise ceases to serve as a director, unless the Board determines otherwise.

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November 05, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 208 $190.32 $39,587.18
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 10

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $190.15 to $190.9450, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

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November 05, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 1,892 $189.56 $358,639.76
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 9

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 408

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $189.07 to $190.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

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November 05, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 1,500 $188.71 $283,069.80
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 8

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,300

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $188.07 to $189.06, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

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November 05, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 200 $187.38 $37,475.56
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 7

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,800

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $186.89 to $187.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

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November 05, 2019 Filed Nov 6, 2019 18:50 UTC Exercise / conversionAmerican Depositary Shares 4,000 $41.01 $164,040.00
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 6

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

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November 04, 2019 Filed Nov 5, 2019 21:22 UTC
Wang XiaodongDirector · Chair, Scientific Advisory Brd
SaleAmerican Depositary Shares 1,000 $190.00 $190,000.00
Disclosure

SEC source: 0001651308-19-000103 · wf-form4_157298891097486.xml · nonDerivative · entry 5

Wang Xiaodong · CIK 0001662982 · Director · Chair, Scientific Advisory Brd

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F3 · security: Each American Depositary Share represents 13 Ordinary Shares.

F4 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

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November 04, 2019 Filed Nov 6, 2019 23:51 UTC
Huang JaneCMO, Hematology
Exercise / conversionShare Option (Right to Buy) · Derivative 427,700 $0.00 Strike: $2.27 $0.00
Disclosure

SEC source: 0001651308-19-000105 · wf-form4_157308428568415.xml · derivative · entry 8

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 617,075

Underlying: Ordinary Shares · 427,700 shares

Expires 2026-09-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

F9 · derivative.exercise_date: These securities vest over a four-year period as follows: 25% on the first anniversary of September 2, 2016 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.

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November 04, 2019 Filed Nov 6, 2019 23:51 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 300 $192.77 $57,831.00
Disclosure

SEC source: 0001651308-19-000105 · wf-form4_157308428568415.xml · nonDerivative · entry 7

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $192.65 to $192.88, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares, sold at each separate price.

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November 04, 2019 Filed Nov 6, 2019 23:51 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 2,854 $191.96 $547,844.42
Disclosure

SEC source: 0001651308-19-000105 · wf-form4_157308428568415.xml · nonDerivative · entry 6

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 300

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $191.53 to $192.34, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares, sold at each separate price.

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November 04, 2019 Filed Nov 6, 2019 23:51 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 12,654 $191.01 $2,417,011.44
Disclosure

SEC source: 0001651308-19-000105 · wf-form4_157308428568415.xml · nonDerivative · entry 5

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,154

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $190.47 to $191.43, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares, sold at each separate price.

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November 04, 2019 Filed Nov 6, 2019 23:51 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 12,523 $190.00 $2,379,398.80
Disclosure

SEC source: 0001651308-19-000105 · wf-form4_157308428568415.xml · nonDerivative · entry 4

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,808

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $189.46 to $190.43, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares, sold at each separate price.

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November 04, 2019 Filed Nov 6, 2019 23:51 UTC
Huang JaneCMO, Hematology
SaleAmerican Depositary Shares 4,569 $189.08 $863,921.14
Disclosure

SEC source: 0001651308-19-000105 · wf-form4_157308428568415.xml · nonDerivative · entry 3

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,331

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $188.46 to $189.45, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares, sold at each separate price.

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November 04, 2019 Filed Nov 6, 2019 23:51 UTC
Huang JaneCMO, Hematology
Exercise / conversionAmerican Depositary Shares 32,900 $29.49 $970,221.00
Disclosure

SEC source: 0001651308-19-000105 · wf-form4_157308428568415.xml · nonDerivative · entry 2

Huang Jane · CIK 0001683913 · CMO, Hematology

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,900

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

Read SEC document
November 04, 2019 Filed Nov 6, 2019 18:50 UTC Exercise / conversionShare Option (Right to Buy) · Derivative 52,000 $0.00 Strike: $3.16 $0.00
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · derivative · entry 12

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 117,988

Underlying: Ordinary Shares · 52,000 shares

Expires 2027-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_price: The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

F12 · derivative.exercise_date: The option shall become exercisable in full upon the earlier to occur of the first anniversary of the grant date or the date of the next annual general meeting; provided, however, that all vesting shall cease if the Reporting Person resigns from the Board or otherwise ceases to serve as a director, unless the Board determines otherwise.

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November 04, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 200 $192.06 $38,411.26
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 11

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $191.42 to $192.40, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

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November 04, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 100 $192.18 $19,218.00
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 5

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

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November 04, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 1,306 $191.32 $249,861.96
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 4

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $190.97 to $191.93, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

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November 04, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 1,394 $190.34 $265,337.72
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 3

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,406

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $189.95 to $190.87, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

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November 04, 2019 Filed Nov 6, 2019 18:50 UTC SaleAmerican Depositary Shares 1,200 $189.37 $227,243.64
Disclosure

SEC source: 0001651308-19-000104 · wf-form4_157308420560017.xml · nonDerivative · entry 2

Chen Timothy Yung-Cheng · CIK 0001374068 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,800

F1 · security: Each American Depositary Share represents 13 Ordinary Shares.

F2 · kind: The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $188.92 to $189.89, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depository Shares, sold at each separate price.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.