OLMA

SEC source: 0001193805-21-001684 · e621128_4-olma.xml · nonDerivative · entry 2

BVF PARTNERS L P/IL · CIK 0001055947 · Director · 10% owner

BIOTECHNOLOGY VALUE FUND L P · CIK 0000918923 · See Explanation of Responses

BVF I GP LLC · CIK 0001803805 · See Explanation of Responses

BIOTECHNOLOGY VALUE FUND II LP · CIK 0001102444 · See Explanation of Responses

BVF II GP LLC · CIK 0001803806 · See Explanation of Responses

Biotechnology Value Trading Fund OS LP · CIK 0001660683 · See Explanation of Responses

BVF Partners OS Ltd. · CIK 0001660684 · See Explanation of Responses

BVF GP HOLDINGS LLC · CIK 0001803809 · 10% owner

BVF INC/IL · CIK 0001056807 · 10% owner

LAMPERT MARK N · CIK 0001233840 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,865,242

F1 · security: This Form 4 is filed jointly by Biotechnology Value Fund, L.P. ("BVF"), Biotechnology Value Fund II, L.P. ("BVF2"), Biotechnology Value Trading Fund OS LP ("Trading Fund OS"), BVF Partners OS Ltd. ("Partners OS"), BVF I GP LLC ("BVF GP"), BVF II GP LLC ("BVF2 GP"), BVF GP Holdings LLC ("BVF GPH"), BVF Partners L.P. ("Partners"), BVF Inc. and Mark N. Lampert (collectively, the "Reporting Persons"). Each of the Reporting Persons is a member of a Section 13(d) group that beneficially owns over 10% of the Issuer's outstanding shares of Common Stock. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein except to the extent of his or its pecuniary interest therein.

F3 · ownership.direct: Securities owned directly by BVF2. As the general partner of BVF2, BVF2 GP may be deemed to beneficially own the securities owned directly by BVF2. As the sole member of BVF2 GP, BVF GPH may be deemed to beneficially own securities owned directly by BVF2. As the investment manager of BVF2, Partners may be deemed to beneficially own the securities owned directly by BVF2. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by BVF2. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by BVF2.

SEC source: 0001193805-21-001684 · e621128_4-olma.xml · nonDerivative · entry 1

BVF PARTNERS L P/IL · CIK 0001055947 · Director · 10% owner

BIOTECHNOLOGY VALUE FUND L P · CIK 0000918923 · See Explanation of Responses

BVF I GP LLC · CIK 0001803805 · See Explanation of Responses

BIOTECHNOLOGY VALUE FUND II LP · CIK 0001102444 · See Explanation of Responses

BVF II GP LLC · CIK 0001803806 · See Explanation of Responses

Biotechnology Value Trading Fund OS LP · CIK 0001660683 · See Explanation of Responses

BVF Partners OS Ltd. · CIK 0001660684 · See Explanation of Responses

BVF GP HOLDINGS LLC · CIK 0001803809 · 10% owner

BVF INC/IL · CIK 0001056807 · 10% owner

LAMPERT MARK N · CIK 0001233840 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,755,093

F1 · security: This Form 4 is filed jointly by Biotechnology Value Fund, L.P. ("BVF"), Biotechnology Value Fund II, L.P. ("BVF2"), Biotechnology Value Trading Fund OS LP ("Trading Fund OS"), BVF Partners OS Ltd. ("Partners OS"), BVF I GP LLC ("BVF GP"), BVF II GP LLC ("BVF2 GP"), BVF GP Holdings LLC ("BVF GPH"), BVF Partners L.P. ("Partners"), BVF Inc. and Mark N. Lampert (collectively, the "Reporting Persons"). Each of the Reporting Persons is a member of a Section 13(d) group that beneficially owns over 10% of the Issuer's outstanding shares of Common Stock. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein except to the extent of his or its pecuniary interest therein.

F2 · ownership.direct: Securities owned directly by BVF. As the general partner of BVF, BVF GP may be deemed to beneficially own the securities owned directly by BVF. As the sole member of BVF GP, BVF GPH may be deemed to beneficially own securities owned directly by BVF. As the investment manager of BVF, Partners may be deemed to beneficially own the securities owned directly by BVF. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by BVF. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by BVF.

SEC source: 0001415889-21-005622 · form4-12012021_021248.xml · nonDerivative · entry 1

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,051,146

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $24.76, and the range of prices were between $24.75 and $24.80. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-005174 · form4-11122021_021156.xml · derivative · entry 5

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,253

Underlying: Common Stock · 22,417 shares

Expires 2030-11-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: One thirty-sixth of the remaining number of shares subject to the option vest on a monthly basis, subject to the Reporting Person's continuous service through each applicable vesting date.

SEC source: 0001415889-21-005174 · form4-11122021_021156.xml · derivative · entry 4

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 162,791

Underlying: Common Stock · 5,251 shares

Expires 2030-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The shares subject to the option vest in a series of 48 successive equal monthly installments measured from June 10, 2020, subject to the Reporting Person's continuous service through each applicable vesting date.

SEC source: 0001415889-21-005174 · form4-11122021_021156.xml · nonDerivative · entry 3

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,790

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: T he weighted average sale price for the transaction reported was $26.88, and the range of prices was between $26.56 and $27.32. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-005174 · form4-11122021_021156.xml · nonDerivative · entry 2

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,458

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-005174 · form4-11122021_021156.xml · nonDerivative · entry 1

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,041

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004934 · form4-10212021_011011.xml · nonDerivative · entry 2

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,051,546

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F3 · price: The weighted average sale price for the transaction reported was $28.20, and the range of prices were between $28.00 and $28.63. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004934 · form4-10212021_011011.xml · nonDerivative · entry 1

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,056,101

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $27.85, and the range of prices were between $27.60 and $28.00. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004885 · form4-10152021_031031.xml · derivative · entry 4

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 966,316

Underlying: Common Stock · 5,000 shares

Expires 2030-11-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: (A) 256,992 of the shares subject to the option vest on September 1, 2021, (B) 2,411 of the shares subject to the option vest on January 1, 2022 and 2,410 of the shares subject to the option vest on January 1 of each of 2023 and 2024 and (C) 23,143 of the shares subject to the option vest on the 1st day of each month (other than on September 1, 2021 and each of January 1, 2022, 2023 and 2024) following September 1, 2021, plus an additional 23 shares on September 1, 2024. Subject to, in each case of (A) - (C) above, the Reporting Person's continuous service on each applicable vesting date. The stock option is early exercisable.

SEC source: 0001415889-21-004885 · form4-10152021_031031.xml · nonDerivative · entry 3

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,514

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F3 · price: The weighted average sale price for the transaction reported was $31.17, and the range of prices were between $31.00 and $31.28. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004885 · form4-10152021_031031.xml · nonDerivative · entry 2

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,865

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $30.42, and the range of prices were between $30.00 and $30.99. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004885 · form4-10152021_031031.xml · nonDerivative · entry 1

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 57,514

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004829 · form4-10122021_031058.xml · derivative · entry 4

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 168,042

Underlying: Common Stock · 5,251 shares

Expires 2030-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The shares subject to the option vest in a series of 48 successive equal monthly installments measured from June 10, 2020, subject to the Reporting Person's continuous service through each applicable vesting date.

SEC source: 0001415889-21-004829 · form4-10122021_031058.xml · nonDerivative · entry 3

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,790

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F3 · price: The weighted average sale price for the transaction reported was $28.19, and the range of prices were between $27.88 and $28.62. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004829 · form4-10122021_031058.xml · nonDerivative · entry 2

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,936

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $27.47, and the range of prices were between $26.88 and $27.87. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004829 · form4-10122021_031058.xml · nonDerivative · entry 1

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,041

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004613 · form4-09292021_040935.xml · derivative · entry 3

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 971,316

Underlying: Common Stock · 1,085 shares

Expires 2030-11-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: (A) 256,992 of the shares subject to the option vest on September 1, 2021, (B) 2,411 of the shares subject to the option vest on January 1, 2022 and 2,410 of the shares subject to the option vest on January 1 of each of 2023 and 2024 and (C) 23,143 of the shares subject to the option vest on the 1st day of each month (other than on September 1, 2021 and each of January 1, 2022, 2023 and 2024) following September 1, 2021, plus an additional 23 shares on September 1, 2024. Subject to, in each case of (A) - (C) above, the Reporting Person's continuous service on each applicable vesting date. The stock option is early exercisable.

SEC source: 0001415889-21-004613 · form4-09292021_040935.xml · nonDerivative · entry 2

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,514

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

SEC source: 0001415889-21-004613 · form4-09292021_040935.xml · nonDerivative · entry 1

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 53,599

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004513 · form4-09212021_030906.xml · nonDerivative · entry 1

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,063,546

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $26.30, and the range of prices were between $25.95 and $26.70. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004370 · form4-09132021_050950.xml · derivative · entry 3

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 173,293

Underlying: Common Stock · 5,251 shares

Expires 2030-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The shares subject to the option vest in a series of 48 successive equal monthly installments measured from June 10, 2020, subject to the Reporting Person's continuous service through each applicable vesting date.

SEC source: 0001415889-21-004370 · form4-09132021_050950.xml · nonDerivative · entry 2

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,790

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $29.38, and the range of prices were between $29.01 and $29.59. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004370 · form4-09132021_050950.xml · nonDerivative · entry 1

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,041

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004306 · form4-09092021_010907.xml · derivative · entry 6

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 972,401

Underlying: Common Stock · 2,631 shares

Expires 2030-11-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: (A) 256,992 of the shares subject to the option vest on September 1, 2021, (B) 2,411 of the shares subject to the option vest on January 1, 2022 and 2,410 of the shares subject to the option vest on January 1 of each of 2023 and 2024 and (C) 23,143 of the shares subject to the option vest on the 1st day of each month (other than on September 1, 2021 and each of January 1, 2022, 2023 and 2024) following September 1, 2021, plus an additional 23 shares on September 1, 2024. Subject to, in each case of (A) - (C) above, the Reporting Person's continuous service on each applicable vesting date. The stock option is early exercisable.

SEC source: 0001415889-21-004306 · form4-09092021_010907.xml · nonDerivative · entry 4

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,514

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

SEC source: 0001415889-21-004306 · form4-09092021_010907.xml · nonDerivative · entry 3

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 56,905

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004306 · form4-09092021_010907.xml · derivative · entry 5

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 975,032

Underlying: Common Stock · 413 shares

Expires 2030-11-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: (A) 256,992 of the shares subject to the option vest on September 1, 2021, (B) 2,411 of the shares subject to the option vest on January 1, 2022 and 2,410 of the shares subject to the option vest on January 1 of each of 2023 and 2024 and (C) 23,143 of the shares subject to the option vest on the 1st day of each month (other than on September 1, 2021 and each of January 1, 2022, 2023 and 2024) following September 1, 2021, plus an additional 23 shares on September 1, 2024. Subject to, in each case of (A) - (C) above, the Reporting Person's continuous service on each applicable vesting date. The stock option is early exercisable.

SEC source: 0001415889-21-004306 · form4-09092021_010907.xml · nonDerivative · entry 2

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,274

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $30.08, and the range of prices were between $30.00 and $30.12. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004306 · form4-09092021_010907.xml · nonDerivative · entry 1

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,687

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-004247 · form4-09032021_020903.xml · derivative · entry 3

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 975,445

Underlying: Common Stock · 871 shares

Expires 2030-11-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: (A) 256,992 of the shares subject to the option vest on September 1, 2021, (B) 2,411 of the shares subject to the option vest on January 1, 2022 and 2,410 of the shares subject to the option vest on January 1 of each of 2023 and 2024 and (C) 23,143 of the shares subject to the option vest on the 1st day of each month (other than on September 1, 2021 and each of January 1, 2022, 2023 and 2024) following September 1, 2021, plus an additional 23 shares on September 1, 2024. Subject to, in each case of (A) - (C) above, the Reporting Person's continuous service on each applicable vesting date. The stock option is early exercisable.

SEC source: 0001415889-21-004247 · form4-09032021_020903.xml · nonDerivative · entry 2

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 54,274

F2 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F3 · price: The weighted average sale price for the transaction reported was $30.05, and the range of prices were between $30.01 and $30.15. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-004247 · form4-09032021_020903.xml · nonDerivative · entry 1

Bohen Sean · CIK 0001831218 · Director · PRESIDENT AND CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,145

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 2,625 shares acquired under the issuer's Employee Stock Purchase Plan on May 14, 2021.

SEC source: 0001415889-21-004029 · form4-08202021_060804.xml · nonDerivative · entry 1

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,075,546

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $24.97, and the range of prices were between $24.75 and $25.46. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-003861 · form4-08112021_030846.xml · derivative · entry 4

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 178,544

Underlying: Common Stock · 5,251 shares

Expires 2030-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: The shares subject to the option vest in a series of 48 successive equal monthly installments measured from June 10, 2020, subject to the Reporting Person's continuous service through each applicable vesting date.

SEC source: 0001415889-21-003861 · form4-08112021_030846.xml · nonDerivative · entry 3

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,790

SEC source: 0001415889-21-003861 · form4-08112021_030846.xml · nonDerivative · entry 2

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,850

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $25.70, and the range of prices were between $25.11 and $26.10. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-003861 · form4-08112021_030846.xml · nonDerivative · entry 1

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,041

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003664 · form4-07212021_020727.xml · nonDerivative · entry 2

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,087,546

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F3 · price: The weighted average sale price for the transaction reported was $25.63, and the range of prices were between $25.14 and $26.10. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-003664 · form4-07212021_020727.xml · nonDerivative · entry 1

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,091,669

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $24.83, and the range of prices were between $24.75 and $24.95. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-003598 · form4-07132021_030746.xml · derivative · entry 4

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 183,795

Underlying: Common Stock · 5,251 shares

Expires 2030-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The shares subject to the option vest in a series of 48 successive equal monthly installments measured from June 10, 2020, subject to the Reporting Person's continuous service through each applicable vesting date.

SEC source: 0001415889-21-003598 · form4-07132021_030746.xml · nonDerivative · entry 3

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,790

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F3 · price: The weighted average sale price for the transaction reported was $27.00, and the range of prices were between $26.80 and $27.16. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-003598 · form4-07132021_030746.xml · nonDerivative · entry 2

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,182

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $26.33, and the range of prices were between $25.74 and $26.72. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-003598 · form4-07132021_030746.xml · nonDerivative · entry 1

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,041

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001415889-21-003129 · form4-06212021_040621.xml · nonDerivative · entry 3

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,099,546

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F4 · price: 2. The weighted average sale price for the transaction reported was $26.30, and the range of prices were between $26.19 and $26.99. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-003129 · form4-06212021_040621.xml · nonDerivative · entry 2

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,100,146

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F3 · price: The weighted average sale price for the transaction reported was $25.59, and the range of prices were between $25.16 and $26.14. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-003129 · form4-06212021_040621.xml · nonDerivative · entry 1

Harmon Cyrus · CIK 0001831410 · Director · CHIEF TECHNOLOGY OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,102,136

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F2 · price: The weighted average sale price for the transaction reported was $24.54, and the range of prices were between $24.18 and $25.14. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.

SEC source: 0001415889-21-002957 · form4-06112021_010653.xml · derivative · entry 5

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 189,046

Underlying: Common Stock · 5,251 shares

Expires 2030-06-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The shares subject to the option vest in a series of 48 successive equal monthly installments measured from June 10, 2020, subject to the Reporting Person's continuous service through each applicable vesting date.

SEC source: 0001415889-21-002957 · form4-06112021_010653.xml · nonDerivative · entry 4

Horn Kinney · CIK 0001831215 · CHIEF BUSINESS OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,790

F1 · kind: The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person.

F4 · price: The weighted average sale price for the transaction reported was $29.97, and the range of prices were between $29.82 and $30.21. Upon request from the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided.