Tapewire

Nasdaq · USD

NBIX

NEUROCRINE BIOSCIENCES INC

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Tapewire entity
2655
SEC CIK
0000914475
Parsed reports
676

Last 12 months

Inside the activity.

0 purchase rows · 40 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202504
Dec 202504
Jan 202602
Feb 202600
Mar 202600
Apr 202600
May 202606
Jun 2026015
Jul 202606
Aug 202600
Sep 202603
Oct 202600

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
November 12, 2020 Filed Nov 16, 2020 23:11 UTC
Gano KyleChief Business Development Off
SaleCommon Stock 2,257 $90.73 $204,770.39
Disclosure

SEC source: 0001209191-20-058543 · doc4.xml · nonDerivative · entry 1

Gano Kyle · CIK 0001567160 · Chief Business Development Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 98,028

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,288 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,031) maintained by the Reporting Person; the disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $88.93 to $92.23. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
November 12, 2020 Filed Nov 16, 2020 23:08 UTC
Bozigian Haig P.Chief Development Officer
SaleCommon Stock 2,257 $90.74 $204,806.50
Disclosure

SEC source: 0001209191-20-058539 · doc4.xml · nonDerivative · entry 1

Bozigian Haig P. · CIK 0001423837 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,694

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,288 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,031) maintained by the Reporting Person; the disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $88.93 to $92.23. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
November 12, 2020 Filed Nov 16, 2020 23:02 UTC
ABERNETHY MATTChief Financial Officer
SaleCommon Stock 2,257 $90.74 $204,810.11
Disclosure

SEC source: 0001209191-20-058532 · doc4.xml · nonDerivative · entry 1

ABERNETHY MATT · CIK 0001724097 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,014

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,288 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,031) maintained by the Reporting Person; the disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $88.93 to $92.23. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
November 02, 2020 Filed Nov 4, 2020 23:09 UTC
BENEVICH ERICChief Commercial Officer
Exercise / conversionNon-Qualified Stock Option · Derivative 20,595 $35.99 Strike: $35.99 $741,214.05
Disclosure

SEC source: 0001209191-20-056981 · doc4.xml · derivative · entry 3

BENEVICH ERIC · CIK 0001643653 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,775

Underlying: Common Stock · 20,595 shares

Expires 2026-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Option granted February 05, 2016 and vested monthly over four years.

Read SEC document
November 02, 2020 Filed Nov 4, 2020 23:09 UTC
BENEVICH ERICChief Commercial Officer
SaleCommon Stock 20,595 $96.53 $1,987,971.51
Disclosure

SEC source: 0001209191-20-056981 · doc4.xml · nonDerivative · entry 2

BENEVICH ERIC · CIK 0001643653 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,374

F1 · kind: The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $94.68 to $98.80. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
November 02, 2020 Filed Nov 4, 2020 23:09 UTC
BENEVICH ERICChief Commercial Officer
Exercise / conversionCommon Stock 20,595 $35.99 $741,214.05
Disclosure

SEC source: 0001209191-20-056981 · doc4.xml · nonDerivative · entry 1

BENEVICH ERIC · CIK 0001643653 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 35,969

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
October 02, 2020 Filed Oct 6, 2020 20:05 UTC
Cooke JulieChief Human Resources Officer
SaleCommon Stock 987 $95.26 $94,021.62
Disclosure

SEC source: 0001209191-20-053998 · doc4.xml · nonDerivative · entry 1

Cooke Julie · CIK 0001776977 · Chief Human Resources Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,549

F1 · kind: Sale of 987 shares of common stock issued upon vesting of 1,875 restricted stock units on October 2, 2020 to cover payroll and withholding taxes, with the balance of the shares (888) maintained by the Reporting Person; the disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 23:51 UTC
ROBERTS EIRYChief Medical Officer
SaleCommon Stock 2,257 $118.84 $268,225.27
Disclosure

SEC source: 0001209191-20-045771 · doc4.xml · nonDerivative · entry 1

ROBERTS EIRY · CIK 0001727606 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,446

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.21 to $120.56. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 23:47 UTC
Lloyd-Smith MalcolmChief Regulatory Officer
SaleCommon Stock 2,257 $118.86 $268,277.40
Disclosure

SEC source: 0001209191-20-045767 · doc4.xml · nonDerivative · entry 1

Lloyd-Smith Malcolm · CIK 0001557146 · Chief Regulatory Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,971

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.21 to $120.56. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 23:40 UTC
Lippoldt DarinChief Legal Officer
SaleCommon Stock 2,257 $118.87 $268,297.26
Disclosure

SEC source: 0001209191-20-045763 · doc4.xml · nonDerivative · entry 1

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,051

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.21 to $120.45. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 23:36 UTC
Grigoriadis Dimitri E.Chief Research Officer
SaleCommon Stock 2,257 $118.83 $268,199.76
Disclosure

SEC source: 0001209191-20-045758 · doc4.xml · nonDerivative · entry 1

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,593

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.29 to $120.56. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 23:29 UTC
GORMAN KEVIN CHARLESDirector · Chief Executive Officer
SaleCommon Stock 3,390 $118.91 $403,101.17
Disclosure

SEC source: 0001209191-20-045753 · doc4.xml · nonDerivative · entry 1

GORMAN KEVIN CHARLES · CIK 0001201096 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 438,021

F1 · kind: Sale of 3,390 shares of common stock issued upon vesting of 6,440 performance restricted stock units to cover withholding taxes, with the balance of the shares (3,050) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.16 to $120.76. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 23:24 UTC
Gano KyleChief Business Development Off
SaleCommon Stock 2,257 $118.87 $268,285.53
Disclosure

SEC source: 0001209191-20-045749 · doc4.xml · nonDerivative · entry 1

Gano Kyle · CIK 0001567160 · Chief Business Development Off

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,997

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.21 to $120.56. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 23:21 UTC
Cooke JulieChief Human Resources Officer
SaleCommon Stock 2,257 $118.91 $268,382.80
Disclosure

SEC source: 0001209191-20-045747 · doc4.xml · nonDerivative · entry 1

Cooke Julie · CIK 0001776977 · Chief Human Resources Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,661

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.21 to $120.56. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 23:14 UTC
Bozigian Haig P.Chief Development Officer
SaleCommon Stock 2,257 $118.89 $268,324.35
Disclosure

SEC source: 0001209191-20-045742 · doc4.xml · nonDerivative · entry 1

Bozigian Haig P. · CIK 0001423837 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,663

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.34 to $120.56. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 22:35 UTC
BENEVICH ERICChief Commercial Officer
SaleCommon Stock 2,257 $118.85 $268,254.16
Disclosure

SEC source: 0001209191-20-045725 · doc4.xml · nonDerivative · entry 1

BENEVICH ERIC · CIK 0001643653 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,374

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.21 to $120.56. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
August 05, 2020 Filed Aug 7, 2020 22:22 UTC
ABERNETHY MATTChief Financial Officer
SaleCommon Stock 2,257 $118.90 $268,355.95
Disclosure

SEC source: 0001209191-20-045716 · doc4.xml · nonDerivative · entry 1

ABERNETHY MATT · CIK 0001724097 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,983

F1 · kind: Sale of 2,257 shares of common stock issued upon vesting of 4,287 performance restricted stock units to cover withholding taxes, with the balance of the shares (2,030) maintained by the Reporting Person. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $118.29 to $120.71. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
July 09, 2020 Filed Jul 10, 2020 20:26 UTC
Lippoldt DarinChief Legal Officer
Exercise / conversionNon-Qualified Stock Option · Derivative 1,657 $35.99 Strike: $35.99 $59,635.43
Disclosure

SEC source: 0001209191-20-042167 · doc4.xml · derivative · entry 3

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,194

Underlying: Common Stock · 1,657 shares

Expires 2026-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Option granted February 5, 2016 and vested monthly over four years.

Read SEC document
July 09, 2020 Filed Jul 10, 2020 20:26 UTC
Lippoldt DarinChief Legal Officer
SaleCommon Stock 1,657 $136.02 $225,385.80
Disclosure

SEC source: 0001209191-20-042167 · doc4.xml · nonDerivative · entry 2

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,021

F1 · kind: The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $136.00 to $136.12. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

Read SEC document
July 09, 2020 Filed Jul 10, 2020 20:26 UTC
Lippoldt DarinChief Legal Officer
Exercise / conversionCommon Stock 1,657 $35.99 $59,635.43
Disclosure

SEC source: 0001209191-20-042167 · doc4.xml · nonDerivative · entry 1

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,678

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 23, 2020 Filed Jun 25, 2020 20:19 UTC
ROBERTS EIRYChief Medical Officer
Exercise / conversionNon-Qualified Stock Option · Derivative 5,000 $77.81 Strike: $77.81 $389,050.00
Disclosure

SEC source: 0001209191-20-038896 · doc4.xml · derivative · entry 3

ROBERTS EIRY · CIK 0001727606 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,860

Underlying: Common Stock · 5,000 shares

Expires 2028-01-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Option granted January 8, 2018 and vests at 25% upon first anniversary (January 8, 2019) and remaining 75% vesting in 36 equal monthly installments beginning February 8, 2019.

Read SEC document
June 23, 2020 Filed Jun 25, 2020 20:19 UTC
ROBERTS EIRYChief Medical Officer
SaleCommon Stock 5,000 $130.00 $650,000.00
Disclosure

SEC source: 0001209191-20-038896 · doc4.xml · nonDerivative · entry 2

ROBERTS EIRY · CIK 0001727606 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,416

F1 · kind: The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

Read SEC document
June 23, 2020 Filed Jun 25, 2020 20:19 UTC
ROBERTS EIRYChief Medical Officer
Exercise / conversionCommon Stock 5,000 $77.81 $389,050.00
Disclosure

SEC source: 0001209191-20-038896 · doc4.xml · nonDerivative · entry 1

ROBERTS EIRY · CIK 0001727606 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,416

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 23, 2020 Filed Jun 25, 2020 20:15 UTC
Lippoldt DarinChief Legal Officer
Exercise / conversionIncentive Stock Option · Derivative 5,000 $32.99 Strike: $32.99 $164,950.00
Disclosure

SEC source: 0001209191-20-038890 · doc4.xml · derivative · entry 3

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,000 shares

Expires 2025-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Option granted February 3, 2015 and vested monthly over four years.

Read SEC document
June 23, 2020 Filed Jun 25, 2020 20:15 UTC
Lippoldt DarinChief Legal Officer
SaleCommon Stock 5,000 $130.00 $650,000.00
Disclosure

SEC source: 0001209191-20-038890 · doc4.xml · nonDerivative · entry 2

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,021

F1 · kind: The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

Read SEC document
June 23, 2020 Filed Jun 25, 2020 20:15 UTC
Lippoldt DarinChief Legal Officer
Exercise / conversionCommon Stock 5,000 $32.99 $164,950.00
Disclosure

SEC source: 0001209191-20-038890 · doc4.xml · nonDerivative · entry 1

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,021

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 11, 2020 Filed Jun 15, 2020 21:31 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionIncentive Stock Option · Derivative 1,049 $43.24 Strike: $43.24 $45,358.76
Disclosure

SEC source: 0001209191-20-036698 · doc4.xml · derivative · entry 6

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,151

Underlying: Common Stock · 1,049 shares

Expires 2027-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Option granted February 6, 2017 and vests monthly over four years.

Read SEC document
June 11, 2020 Filed Jun 15, 2020 21:31 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionIncentive Stock Option · Derivative 1,812 $35.99 Strike: $35.99 $65,213.88
Disclosure

SEC source: 0001209191-20-036698 · doc4.xml · derivative · entry 5

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,812 shares

Expires 2026-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Option granted February 5, 2016 and vested monthly over four years.

Read SEC document
June 11, 2020 Filed Jun 15, 2020 21:31 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionIncentive Stock Option · Derivative 2,710 $32.99 Strike: $32.99 $89,402.90
Disclosure

SEC source: 0001209191-20-036698 · doc4.xml · derivative · entry 4

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,710 shares

Expires 2025-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Option granted February 3, 2015 and vested monthly over four years.

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June 11, 2020 Filed Jun 15, 2020 21:31 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionCommon Stock 1,049 $43.24 $45,358.76
Disclosure

SEC source: 0001209191-20-036698 · doc4.xml · nonDerivative · entry 3

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 77,563

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 11, 2020 Filed Jun 15, 2020 21:31 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionCommon Stock 1,812 $35.99 $65,213.88
Disclosure

SEC source: 0001209191-20-036698 · doc4.xml · nonDerivative · entry 2

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,514

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
June 11, 2020 Filed Jun 15, 2020 21:31 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionCommon Stock 2,710 $32.99 $89,402.90
Disclosure

SEC source: 0001209191-20-036698 · doc4.xml · nonDerivative · entry 1

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 74,702

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 19, 2020 Filed May 20, 2020 22:59 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionNon-Qualified Stock Option · Derivative 10,000 $35.99 Strike: $35.99 $359,900.00
Disclosure

SEC source: 0001209191-20-031028 · doc4.xml · derivative · entry 7

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,588

Underlying: Common Stock · 10,000 shares

Expires 2026-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Option granted February 5, 2016 and vested monthly over four years.

Read SEC document
May 19, 2020 Filed May 20, 2020 22:59 UTC
Grigoriadis Dimitri E.Chief Research Officer
SaleCommon Stock 32,749 $126.73 $4,150,133.40
Disclosure

SEC source: 0001209191-20-031028 · doc4.xml · nonDerivative · entry 5

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 71,992

F1 · kind: The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

F2 · price: Represents a weighted average sales price per share. These shares were sold in multiple transactions at prices ranging from $125.91 to $127.25. The Reporting Person has provided to the issuer, and will provide to any security holder of the issuer or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.

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May 19, 2020 Filed May 20, 2020 22:59 UTC
Grigoriadis Dimitri E.Chief Research Officer
SaleCommon Stock 10,000 $125.98 $1,259,800.00
Disclosure

SEC source: 0001209191-20-031028 · doc4.xml · nonDerivative · entry 4

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,741

F1 · kind: The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

Read SEC document
May 19, 2020 Filed May 20, 2020 22:59 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionCommon Stock 10,000 $35.99 $359,900.00
Disclosure

SEC source: 0001209191-20-031028 · doc4.xml · nonDerivative · entry 3

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 114,741

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 19, 2020 Filed May 21, 2020 23:00 UTC GrantNon-Qualified Stock Option · Derivative 6,018 $0.00 Strike: $119.93 $0.00
Disclosure

SEC source: 0001209191-20-031502 · doc4.xml · derivative · entry 1

SHERWIN STEPHEN A · CIK 0001079462 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,018

Underlying: Common Stock · 6,018 shares

Expires 2030-05-19

F1 · derivative.exercise_date: Option vests in 12 equal monthly installments beginning June 19, 2020.

Read SEC document
May 19, 2020 Filed May 21, 2020 22:59 UTC GrantNon-Qualified Stock Option · Derivative 6,018 $0.00 Strike: $119.93 $0.00
Disclosure

SEC source: 0001209191-20-031499 · doc4.xml · derivative · entry 1

POPS RICHARD F · CIK 0001126490 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,018

Underlying: Common Stock · 6,018 shares

Expires 2030-05-19

F1 · derivative.exercise_date: Option vests in 12 equal monthly installments beginning June 19, 2020.

Read SEC document
May 19, 2020 Filed May 21, 2020 22:57 UTC GrantNon-Qualified Stock Option · Derivative 6,018 $0.00 Strike: $119.93 $0.00
Disclosure

SEC source: 0001209191-20-031496 · doc4.xml · derivative · entry 1

Norwalk Leslie V · CIK 0001533568 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,018

Underlying: Common Stock · 6,018 shares

Expires 2030-05-19

F1 · derivative.exercise_date: Option vests in 12 equal monthly installments beginning June 19, 2020.

Read SEC document
May 19, 2020 Filed May 21, 2020 22:55 UTC GrantNon-Qualified Stock Option · Derivative 6,018 $0.00 Strike: $119.93 $0.00
Disclosure

SEC source: 0001209191-20-031493 · doc4.xml · derivative · entry 1

MORROW GEORGE J · CIK 0001068754 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,018

Underlying: Common Stock · 6,018 shares

Expires 2030-05-19

F1 · derivative.exercise_date: Option vests in 12 equal monthly installments beginning June 19, 2020.

Read SEC document
May 19, 2020 Filed May 21, 2020 22:52 UTC
LYONS GARY ADirector
GrantNon-Qualified Stock Option · Derivative 6,018 $0.00 Strike: $119.93 $0.00
Disclosure

SEC source: 0001209191-20-031486 · doc4.xml · derivative · entry 1

LYONS GARY A · CIK 0001123343 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,018

Underlying: Common Stock · 6,018 shares

Expires 2030-05-19

F1 · derivative.exercise_date: Option vests in 12 equal monthly installments beginning June 19, 2020.

Read SEC document
May 19, 2020 Filed May 21, 2020 22:42 UTC GrantNon-Qualified Stock Option · Derivative 6,018 $0.00 Strike: $119.93 $0.00
Disclosure

SEC source: 0001209191-20-031463 · doc4.xml · derivative · entry 1

RASTETTER WILLIAM H · CIK 0001205903 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,018

Underlying: Common Stock · 6,018 shares

Expires 2030-05-19

F1 · derivative.exercise_date: Option vests in 12 equal monthly installments beginning June 19, 2020.

Read SEC document
May 18, 2020 Filed May 20, 2020 23:15 UTC
Lippoldt DarinChief Legal Officer
Exercise / conversionIncentive Stock Option · Derivative 5,000 $32.99 Strike: $32.99 $164,950.00
Disclosure

SEC source: 0001209191-20-031033 · doc4.xml · derivative · entry 3

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2025-02-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: Option granted February 3, 2015 and vested monthly over four years.

Read SEC document
May 18, 2020 Filed May 20, 2020 23:15 UTC
Lippoldt DarinChief Legal Officer
SaleCommon Stock 5,000 $120.00 $600,000.00
Disclosure

SEC source: 0001209191-20-031033 · doc4.xml · nonDerivative · entry 2

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,021

F1 · kind: The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

Read SEC document
May 18, 2020 Filed May 20, 2020 23:15 UTC
Lippoldt DarinChief Legal Officer
Exercise / conversionCommon Stock 5,000 $32.99 $164,950.00
Disclosure

SEC source: 0001209191-20-031033 · doc4.xml · nonDerivative · entry 1

Lippoldt Darin · CIK 0001504783 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 31,021

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 18, 2020 Filed May 20, 2020 22:59 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionNon-Qualified Stock Option · Derivative 10,000 $35.99 Strike: $35.99 $359,900.00
Disclosure

SEC source: 0001209191-20-031028 · doc4.xml · derivative · entry 6

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,588

Underlying: Common Stock · 10,000 shares

Expires 2026-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Option granted February 5, 2016 and vested monthly over four years.

Read SEC document
May 18, 2020 Filed May 20, 2020 22:59 UTC
Grigoriadis Dimitri E.Chief Research Officer
SaleCommon Stock 10,000 $119.98 $1,199,800.00
Disclosure

SEC source: 0001209191-20-031028 · doc4.xml · nonDerivative · entry 2

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,741

F1 · kind: The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person at least 60 days prior to the transaction date in Box 3 above. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan.

Read SEC document
May 18, 2020 Filed May 20, 2020 22:59 UTC
Grigoriadis Dimitri E.Chief Research Officer
Exercise / conversionCommon Stock 10,000 $35.99 $359,900.00
Disclosure

SEC source: 0001209191-20-031028 · doc4.xml · nonDerivative · entry 1

Grigoriadis Dimitri E. · CIK 0001423838 · Chief Research Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 114,741

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
May 12, 2020 Filed May 15, 2020 00:09 UTC
Bozigian Haig P.Chief Development Officer
Exercise / conversionNon-Qualified Stock Option · Derivative 18,057 $0.00 Strike: $81.05 $0.00
Disclosure

SEC source: 0001209191-20-029401 · doc4.xml · derivative · entry 12

Bozigian Haig P. · CIK 0001423837 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,383

Underlying: Common Stock · 18,057 shares

Expires 2029-02-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: Option granted February 07, 2019 and vests monthly over four years.

Read SEC document
May 12, 2020 Filed May 15, 2020 00:09 UTC
Bozigian Haig P.Chief Development Officer
Exercise / conversionNon-Qualified Stock Option · Derivative 15,833 $0.00 Strike: $81.49 $0.00
Disclosure

SEC source: 0001209191-20-029401 · doc4.xml · derivative · entry 11

Bozigian Haig P. · CIK 0001423837 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,340

Underlying: Common Stock · 15,833 shares

Expires 2028-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: Option granted February 05, 2018 and vests monthly over four years.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.