MIRM

SEC source: 0001650131-26-000010 · form4-03172026_070307.xml · nonDerivative · entry 2

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,787

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each performance restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001650131-26-000010 · form4-03172026_070307.xml · nonDerivative · entry 1

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,787

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each performance restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001614740-26-000009 · form4-03172026_070301.xml · derivative · entry 6

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 50,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each performance restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F4 · derivative.exercise_date: The shares vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

F4 · derivative.expiration_date: The shares vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

SEC source: 0001614740-26-000009 · form4-03172026_070301.xml · derivative · entry 5

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 25,000 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each performance restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The shares vest as follows: 2/3 of the shares vest on March 15, 2025 and 1/3 of the shares vest on March 15, 2026.

F3 · derivative.expiration_date: The shares vest as follows: 2/3 of the shares vest on March 15, 2025 and 1/3 of the shares vest on March 15, 2026.

SEC source: 0001614740-26-000009 · form4-03172026_070301.xml · nonDerivative · entry 2

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 235,294

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each performance restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001614740-26-000009 · form4-03172026_070301.xml · nonDerivative · entry 1

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 185,294

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each performance restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001650131-26-000008 · form4-03112026_080315.xml · derivative · entry 2

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,088

Underlying: Common Stock · 5,912 shares

Expires 2032-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The stock option is fully vested.

SEC source: 0001650131-26-000008 · form4-03112026_080315.xml · nonDerivative · entry 1

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,567

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001547959-26-000005 · form4-02172026_090212.xml · derivative · entry 3

Ramasastry Saira · CIK 0001547959 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,000

Underlying: Common Stock · 2,000 shares

Expires 2032-06-01

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The stock option is fully vested.

SEC source: 0001547959-26-000005 · form4-02172026_090212.xml · nonDerivative · entry 2

Ramasastry Saira · CIK 0001547959 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Reported transaction occurred pursuant to a Rule 10b5-1 Plan adopted by the reporting person on September 18, 2025.

SEC source: 0001547959-26-000005 · form4-02172026_090212.xml · nonDerivative · entry 1

Ramasastry Saira · CIK 0001547959 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001974200-26-000006 · form4-02032026_090202.xml · nonDerivative · entry 2

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,503

F2 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

SEC source: 0001650131-26-000007 · form4-02032026_090206.xml · nonDerivative · entry 1

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,655

F1 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

SEC source: 0001614740-26-000007 · form4-02032026_090204.xml · nonDerivative · entry 1

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 160,294

F1 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

SEC source: 0001974200-26-000006 · form4-02032026_090202.xml · derivative · entry 3

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,771 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

F3 · derivative.exercise_date: The restricted stock units vest in a series of three successive equal annual installments beginning January 31, 2024. 1,772 shares vested on January 31, 2024 ; 1,772 shares vested January 31, 2025 and the remaining 1,771 shares will vest on January 31, 2026.

F3 · derivative.expiration_date: The restricted stock units vest in a series of three successive equal annual installments beginning January 31, 2024. 1,772 shares vested on January 31, 2024 ; 1,772 shares vested January 31, 2025 and the remaining 1,771 shares will vest on January 31, 2026.

SEC source: 0001974200-26-000006 · form4-02032026_090202.xml · nonDerivative · entry 1

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,471

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

SEC source: 0001974200-26-000004 · form4-01302026_060108.xml · derivative · entry 3

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,000

Underlying: Common Stock · 9,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F4 · derivative.exercise_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

F4 · derivative.expiration_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

SEC source: 0001974200-26-000004 · form4-01302026_060108.xml · derivative · entry 2

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,970

Underlying: Common Stock · 4,970 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001974200-26-000004 · form4-01302026_060108.xml · derivative · entry 1

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,680

Underlying: Common Stock · 7,680 shares

Expires 2036-01-27

F1 · derivative.exercise_date: 1/4th of the shares vest one year after January 28, 2026 (the "Vesting Commencement Date") and the balance of the shares vest in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date.

SEC source: 0001670138-26-000003 · form4-01302026_060106.xml · derivative · entry 3

Quan Joanne · CIK 0001670138 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F4 · derivative.exercise_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

F4 · derivative.expiration_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

SEC source: 0001670138-26-000003 · form4-01302026_060106.xml · derivative · entry 2

Quan Joanne · CIK 0001670138 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,760

Underlying: Common Stock · 11,760 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001670138-26-000003 · form4-01302026_060106.xml · derivative · entry 1

Quan Joanne · CIK 0001670138 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,140

Underlying: Common Stock · 18,140 shares

Expires 2036-01-27

F1 · derivative.exercise_date: 1/4th of the shares vest one year after January 28, 2026 (the "Vesting Commencement Date") and the balance of the shares vest in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date.

SEC source: 0001197350-26-000004 · form4-01302026_060105.xml · derivative · entry 3

BJERKHOLT ERIC · CIK 0001197350 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F4 · derivative.exercise_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

F4 · derivative.expiration_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

SEC source: 0001197350-26-000004 · form4-01302026_060105.xml · derivative · entry 2

BJERKHOLT ERIC · CIK 0001197350 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,760

Underlying: Common Stock · 11,760 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001197350-26-000004 · form4-01302026_060105.xml · derivative · entry 1

BJERKHOLT ERIC · CIK 0001197350 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,140

Underlying: Common Stock · 18,140 shares

Expires 2036-01-27

F1 · derivative.exercise_date: 1/4th of the shares vest one year after January 28, 2026 (the "Vesting Commencement Date") and the balance of the shares vest in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date.

SEC source: 0001650131-26-000005 · form4-01302026_060103.xml · derivative · entry 3

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,500

Underlying: Common Stock · 34,500 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F4 · derivative.exercise_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

F4 · derivative.expiration_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

SEC source: 0001650131-26-000005 · form4-01302026_060103.xml · derivative · entry 2

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,280

Underlying: Common Stock · 16,280 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001650131-26-000005 · form4-01302026_060103.xml · derivative · entry 1

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,120

Underlying: Common Stock · 25,120 shares

Expires 2036-01-27

F1 · derivative.exercise_date: 1/4th of the shares vest one year after January 28, 2026 (the "Vesting Commencement Date") and the balance of the shares vest in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date.

SEC source: 0001614740-26-000005 · form4-01302026_060101.xml · derivative · entry 3

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,000

Underlying: Common Stock · 75,000 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F4 · derivative.exercise_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

F4 · derivative.expiration_date: On January 23, 2024, the reporting person was granted performance restricted stock units ("PSUs") which vest upon satisfaction of certain performance criteria. On January 28, 2026, performance criteria were determined to have been met. The shares subject to the PSUs vest as follows: 2/3 of the shares vest on March 15, 2026 and 1/3 of the shares vest on March 15, 2027.

SEC source: 0001614740-26-000005 · form4-01302026_060101.xml · derivative · entry 2

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,500

Underlying: Common Stock · 43,500 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 28, 2026 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001614740-26-000005 · form4-01302026_060101.xml · derivative · entry 1

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,000

Underlying: Common Stock · 67,000 shares

Expires 2036-01-27

F1 · derivative.exercise_date: 1/4th of the shares vest one year after January 28, 2026 (the "Vesting Commencement Date") and the balance of the shares vest in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date.

SEC source: 0001974200-26-000002 · form4-01272026_040105.xml · nonDerivative · entry 2

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,700

F2 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

SEC source: 0001197350-26-000002 · form4-01272026_040108.xml · nonDerivative · entry 2

BJERKHOLT ERIC · CIK 0001197350 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,741

F2 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

SEC source: 0001650131-26-000003 · form4-01272026_040106.xml · nonDerivative · entry 2

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,286

F2 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

SEC source: 0001614740-26-000003 · form4-01272026_040103.xml · nonDerivative · entry 2

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 169,402

F2 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

SEC source: 0001974200-26-000002 · form4-01272026_040105.xml · derivative · entry 3

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,500

Underlying: Common Stock · 1,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 23, 2024 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 23, 2024 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001974200-26-000002 · form4-01272026_040105.xml · nonDerivative · entry 1

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,542

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

SEC source: 0001197350-26-000002 · form4-01272026_040108.xml · derivative · entry 3

BJERKHOLT ERIC · CIK 0001197350 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,666

Underlying: Common Stock · 2,667 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 23, 2024 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 23, 2024 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001197350-26-000002 · form4-01272026_040108.xml · nonDerivative · entry 1

BJERKHOLT ERIC · CIK 0001197350 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,794

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

SEC source: 0001650131-26-000003 · form4-01272026_040106.xml · derivative · entry 3

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,750

Underlying: Common Stock · 5,750 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 23, 2024 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 23, 2024 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001650131-26-000003 · form4-01272026_040106.xml · nonDerivative · entry 1

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,429

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

SEC source: 0001614740-26-000003 · form4-01272026_040103.xml · derivative · entry 4

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 23, 2024 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

F3 · derivative.expiration_date: 1/3rd of the shares subject to the restricted stock units shall vest on each anniversary of January 23, 2024 (the "Vesting Commencement Date"), such that the entire award will be vested on the three-year anniversary of the Vesting Commencement Date.

SEC source: 0001614740-26-000003 · form4-01272026_040103.xml · nonDerivative · entry 1

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 176,233

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001365617-26-000002 · form4-01272026_090122.xml · nonDerivative · entry 2

Heron Patrick J · CIK 0001365617 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Frazier Life Sciences X, L.P.

Disclosed balance after: 459,010

F2 · ownership.nature: The shares are held directly by Frazier Life Sciences X, L.P. FHMLS X, L.P. is the general partner of Frazier Life Sciences X, L.P. and FHMLS X, L.L.C. is the general partner of FHMLS X, L.P. The Reporting Person is one of two managing members of FHMLS X, L.L.C. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001365617-26-000002 · form4-01272026_090122.xml · nonDerivative · entry 1

Heron Patrick J · CIK 0001365617 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · By Frazier Life Sciences X, L.P.

Disclosed balance after: 327,585

F1 · kind: Frazier Life Sciences X, L.P. received these shares in connection with merger of Bluejay Therapeutics, Inc. into the Issuer (the "Merger"). On the effective date of the Merger, the closing price of the Issuer's Common Stock was $94.29 per share.

F1 · price: Frazier Life Sciences X, L.P. received these shares in connection with merger of Bluejay Therapeutics, Inc. into the Issuer (the "Merger"). On the effective date of the Merger, the closing price of the Issuer's Common Stock was $94.29 per share.

F2 · ownership.nature: The shares are held directly by Frazier Life Sciences X, L.P. FHMLS X, L.P. is the general partner of Frazier Life Sciences X, L.P. and FHMLS X, L.L.C. is the general partner of FHMLS X, L.P. The Reporting Person is one of two managing members of FHMLS X, L.L.C. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein.

SEC source: 0001974200-26-000001 · form4-01232026_050110.xml · nonDerivative · entry 2

Howe Jolanda · CIK 0001974200 · SVP, GLOBAL CONTROLLER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,042

F2 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

SEC source: 0001670138-26-000002 · form4-01232026_050108.xml · nonDerivative · entry 2

Quan Joanne · CIK 0001670138 · CHIEF MEDICAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,817

F2 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

SEC source: 0001197350-26-000001 · form4-01232026_050106.xml · nonDerivative · entry 2

BJERKHOLT ERIC · CIK 0001197350 · CHIEF FINANCIAL OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 42,127

F3 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock (or its cash equivalent, at the discretion of the Issuer).

SEC source: 0001650131-26-000002 · form4-01232026_050104.xml · nonDerivative · entry 2

Radovich Peter · CIK 0001650131 · PRESIDENT AND COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,679

F3 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.

SEC source: 0001614740-26-000002 · form4-01232026_050101.xml · nonDerivative · entry 2

Peetz Christopher · CIK 0001614740 · Director · CHIEF EXECUTIVE OFFICER

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 163,733

F2 · kind: Shares sold to cover tax withholding obligations associated with the vesting of restricted stock units.