LXRX

SEC source: 0001127602-21-008768 · form4.xml · derivative · entry 9

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 169,260

Underlying: Common Stock · 84,630 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F6 · derivative.exercise_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

F6 · derivative.expiration_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

SEC source: 0001127602-21-008768 · form4.xml · derivative · entry 8

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,380

Underlying: Common Stock · 79,380 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F5 · derivative.exercise_date: Restricted stock units vest with respect to one third of the shares subject to the restricted stock units on February 28, 2020 and vest an additional one third on February 28 of each of the two succeeding years thereafter.

F5 · derivative.expiration_date: Restricted stock units vest with respect to one third of the shares subject to the restricted stock units on February 28, 2020 and vest an additional one third on February 28 of each of the two succeeding years thereafter.

SEC source: 0001127602-21-008768 · form4.xml · derivative · entry 7

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 23,513 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F4 · derivative.exercise_date: Restricted stock units vest with respect to one third of the shares subject to the restricted stock units on February 28, 2019 and vest an additional one third on February 28 of each of the two succeeding years thereafter.

F4 · derivative.expiration_date: Restricted stock units vest with respect to one third of the shares subject to the restricted stock units on February 28, 2019 and vest an additional one third on February 28 of each of the two succeeding years thereafter.

SEC source: 0001127602-21-008768 · form4.xml · derivative · entry 6

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,362 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F3 · derivative.exercise_date: Restricted stock units vest with respect to 25% of the shares subject to the restricted stock units on February 28, 2018 and vest an additional 25% on February 28 of each of the three succeeding years thereafter.

F3 · derivative.expiration_date: Restricted stock units vest with respect to 25% of the shares subject to the restricted stock units on February 28, 2018 and vest an additional 25% on February 28 of each of the three succeeding years thereafter.

SEC source: 0001127602-21-008768 · form4.xml · nonDerivative · entry 5

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 436,713

F2 · kind: Withholding of a portion of issued shares by the Company in satisfaction of shareholder's tax withholding obligations with respect thereto.

SEC source: 0001127602-21-008768 · form4.xml · nonDerivative · entry 4

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 491,751

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-21-008768 · form4.xml · nonDerivative · entry 3

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 407,121

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-21-008768 · form4.xml · nonDerivative · entry 2

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 327,741

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-21-008768 · form4.xml · nonDerivative · entry 1

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 304,228

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-21-005885 · form4.xml · derivative · entry 2

WADE JEFFREY L · CIK 0001225767 · EVP, Corp Adm Affairs and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,600

Underlying: Common Stock · 100,600 shares

Expires 2031-02-11

F3 · derivative.exercise_date: Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant, and vests 1/48th per month for each month of service thereafter.

SEC source: 0001127602-21-005885 · form4.xml · derivative · entry 1

WADE JEFFREY L · CIK 0001225767 · EVP, Corp Adm Affairs and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,530

Underlying: Common Stock · 33,530 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

F2 · derivative.expiration_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

SEC source: 0001127602-21-005882 · form4.xml · derivative · entry 2

TYLE PRAVEEN · CIK 0001296936 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,310

Underlying: Common Stock · 96,310 shares

Expires 2031-02-11

F3 · derivative.exercise_date: Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant, and vests 1/48th per month for each month of service thereafter.

SEC source: 0001127602-21-005882 · form4.xml · derivative · entry 1

TYLE PRAVEEN · CIK 0001296936 · EVP, R&D

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,100

Underlying: Common Stock · 32,100 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

F2 · derivative.expiration_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

SEC source: 0001127602-21-005838 · form4.xml · derivative · entry 2

Tessmer James F · CIK 0001434095 · VP, Finance & Accounting

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,340

Underlying: Common Stock · 24,340 shares

Expires 2031-02-11

F3 · derivative.exercise_date: Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant, and vests 1/48th per month for each month of service thereafter.

SEC source: 0001127602-21-005838 · form4.xml · derivative · entry 1

Tessmer James F · CIK 0001434095 · VP, Finance & Accounting

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,230

Underlying: Common Stock · 16,230 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

F2 · derivative.expiration_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

SEC source: 0001127602-21-005837 · form4.xml · derivative · entry 2

MAIN ALAN J · CIK 0001227372 · EVP, Innov & Chem Sciences

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 80,780

Underlying: Common Stock · 80,780 shares

Expires 2031-02-11

F3 · derivative.exercise_date: Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant, and vests 1/48th per month for each month of service thereafter.

SEC source: 0001127602-21-005837 · form4.xml · derivative · entry 1

MAIN ALAN J · CIK 0001227372 · EVP, Innov & Chem Sciences

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,930

Underlying: Common Stock · 26,930 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

F2 · derivative.expiration_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

SEC source: 0001127602-21-005835 · form4.xml · derivative · entry 2

Crum Brian T · CIK 0001792747 · VP, General Counsel & Secr.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 78,760

Underlying: Common Stock · 78,760 shares

Expires 2031-02-11

F3 · derivative.exercise_date: Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant, and vests 1/48th per month for each month of service thereafter.

SEC source: 0001127602-21-005835 · form4.xml · derivative · entry 1

Crum Brian T · CIK 0001792747 · VP, General Counsel & Secr.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,250

Underlying: Common Stock · 26,250 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

F2 · derivative.expiration_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

SEC source: 0001127602-21-005833 · form4.xml · derivative · entry 2

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 300,000

Underlying: Common Stock · 300,000 shares

Expires 2031-02-11

F3 · derivative.exercise_date: Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant, and vests 1/48th per month for each month of service thereafter.

SEC source: 0001127602-21-005833 · form4.xml · derivative · entry 1

COATS LONNEL · CIK 0001612528 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires not disclosed

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

F2 · derivative.expiration_date: Restricted stock units vest with respect to 1/3 of the shares subject to the restricted stock units on February 28 of each of the three years following the year of grant.

SEC source: 0000899243-21-000539 · doc4.xml · nonDerivative · entry 1

Invus C.V. · CIK 0001378005 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

F1 · kind: On December 31, 2020, Invus C.V. dissolved and transferred the shares of Class A common stock of the Issuer held by it to Invus Partners, LLC.

F1 · price: On December 31, 2020, Invus C.V. dissolved and transferred the shares of Class A common stock of the Issuer held by it to Invus Partners, LLC.

SEC source: 0000899243-20-034271 · doc4.xml · nonDerivative · entry 1

Artal International S.C.A. · CIK 0001218180 · Director · 10% owner

Minne Pascal · CIK 0001460839 · Director · 10% owner

Artal International Management S.A. · CIK 0001522131 · Director · 10% owner

Artal Group S.A. · CIK 0001053906 · Director · 10% owner

Westend S.A. · CIK 0001283968 · Director · 10% owner

Stichting Administratiekantoor Westend · CIK 0001460840 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 32,259,461

F1 · kind: On December 11, 2020, Artal International S.C.A. entered into a subscription agreement with the Issuer and other parties thereto, pursuant to which Artal International S.C.A. agreed to purchase 10,937,500 shares of Class A common stock of the Issuer at a price of $3.20 per share. The purchase closed on December 16, 2020.

F2 · ownership.nature: These securities are directly held by Artal International S.C.A.

F5 · ownership.nature: Invus Public Equities Advisors, LLC is the general partner of Invus Public Equities, L.P., and Invus Advisors, L.L.C. is the general partner of Invus, L.P. Artal Treasury Limited is the managing member of Invus Public Equities Advisors, LLC. Artal International S.C.A. is the managing member of Invus Advisors, L.L.C. and, through its Geneva branch, is the sole stockholder of Artal Treasury Limited. The managing partner of Artal International S.C.A. is Artal International Management S.A. The parent company of Artal International Management S.A. is Artal Group S.A. The parent company of Artal Group S.A. is Westend S.A. The majority stockholder of Westend S.A. is Stichting Administratiekantoor Westend (the "Stichting"). Mr. Pascal Minne is the sole member of the board of the Stichting.

F6 · ownership.nature: Each of the Reporting Persons (other than to the extent it directly holds securities reported herein) disclaims beneficial ownership of the securities held by the other Reporting Persons, except to the extent of such Reporting Person's pecuniary interest therein, and, pursuant to Rule 16a-1(a)(4) under the Exchange Act, each of the Reporting Persons (other than to the extent it directly holds securities reported herein) states that the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 of the Exchange Act or for any other purpose.

F7 · ownership.nature: Due to the limitations of the electronic filing system certain Reporting Persons are filing a separate Form 4.

SEC source: 0000899243-20-034268 · doc4.xml · nonDerivative · entry 1

Invus Public Equities, L.P. · CIK 0001340097 · Director · 10% owner

Artal Treasury Ltd · CIK 0001766952 · Director · 10% owner

Invus, L.P. · CIK 0001404570 · Director · 10% owner

Invus Public Equities Advisors, LLC · CIK 0001340096 · Director · 10% owner

Invus Advisors, L.L.C. · CIK 0001404553 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 32,259,461

F1 · kind: On December 11, 2020, Artal International S.C.A. entered into a subscription agreement with the Issuer and other parties thereto, pursuant to which Artal International S.C.A. agreed to purchase 10,937,500 shares of Class A common stock of the Issuer at a price of $3.20 per share. The purchase closed on December 16, 2020.

F2 · ownership.nature: These securities are directly held by Artal International S.C.A.

F5 · ownership.nature: Invus Public Equities Advisors, LLC is the general partner of Invus Public Equities, L.P., and Invus Advisors, L.L.C. is the general partner of Invus, L.P. Artal Treasury Limited is the managing member of Invus Public Equities Advisors, LLC. Artal International S.C.A. is the managing member of Invus Advisors, L.L.C. and, through its Geneva branch, is the sole stockholder of Artal Treasury Limited. The managing partner of Artal International S.C.A. is Artal International Management S.A. The parent company of Artal International Management S.A. is Artal Group S.A. The parent company of Artal Group S.A. is Westend S.A. The majority stockholder of Westend S.A. is Stichting Administratiekantoor Westend (the "Stichting"). Mr. Pascal Minne is the sole member of the board of the Stichting.

F6 · ownership.nature: Each of the Reporting Persons (other than to the extent it directly holds securities reported herein) disclaims beneficial ownership of the securities held by the other Reporting Persons, except to the extent of such Reporting Person's pecuniary interest therein, and, pursuant to Rule 16a-1(a)(4) under the Exchange Act, each of the Reporting Persons (other than to the extent it directly holds securities reported herein) states that the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 of the Exchange Act or for any other purpose.

F7 · ownership.nature: Due to the limitations of the electronic filing system certain Reporting Persons are filing a separate Form 4.

SEC source: 0001127602-20-014562 · form4.xml · derivative · entry 4

BARKER SAM L · CIK 0001226877 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,466 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014562 · form4.xml · nonDerivative · entry 1

BARKER SAM L · CIK 0001226877 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 55,653

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-20-014572 · form4.xml · derivative · entry 4

Swain Judith L · CIK 0001413573 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,466 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014572 · form4.xml · nonDerivative · entry 1

Swain Judith L · CIK 0001413573 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,368

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-20-014570 · form4.xml · derivative · entry 4

SOBECKI CHRISTOPHER J · CIK 0001053892 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,466 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014570 · form4.xml · nonDerivative · entry 1

SOBECKI CHRISTOPHER J · CIK 0001053892 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 140,759

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-20-014568 · form4.xml · derivative · entry 4

Palantoni Frank · CIK 0001307963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,466 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014568 · form4.xml · nonDerivative · entry 1

Palantoni Frank · CIK 0001307963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,368

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-20-014566 · form4.xml · derivative · entry 4

NIES ALAN S · CIK 0001270260 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,466 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014566 · form4.xml · nonDerivative · entry 1

NIES ALAN S · CIK 0001270260 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,082

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-20-014565 · form4.xml · derivative · entry 4

LEFKOWITZ ROBERT J MD · CIK 0001226385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,466 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014565 · form4.xml · nonDerivative · entry 1

LEFKOWITZ ROBERT J MD · CIK 0001226385 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,368

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-20-014563 · form4.xml · derivative · entry 5

DEBBANE RAYMOND · CIK 0001053890 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,466 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014563 · form4.xml · nonDerivative · entry 1

DEBBANE RAYMOND · CIK 0001053890 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 316,883

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-20-014560 · form4.xml · derivative · entry 4

Amouyal Philippe · CIK 0001376854 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 3,466 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of common stock.

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014560 · form4.xml · nonDerivative · entry 1

Amouyal Philippe · CIK 0001376854 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,368

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001127602-20-014562 · form4.xml · derivative · entry 3

BARKER SAM L · CIK 0001226877 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,638

Underlying: Common Stock · 10,638 shares

Expires not disclosed

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014562 · form4.xml · derivative · entry 2

BARKER SAM L · CIK 0001226877 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,115

Underlying: Common Stock · 18,115 shares

Expires 2030-04-24

F1 · derivative.exercise_date: Option vests with respect to one third of the shares subject to the option on each of the first three anniversaries of the grant date.

SEC source: 0001127602-20-014572 · form4.xml · derivative · entry 3

Swain Judith L · CIK 0001413573 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,638

Underlying: Common Stock · 10,638 shares

Expires not disclosed

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014572 · form4.xml · derivative · entry 2

Swain Judith L · CIK 0001413573 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,115

Underlying: Common Stock · 18,115 shares

Expires 2030-04-24

F1 · derivative.exercise_date: Option vests with respect to one third of the shares subject to the option on each of the first three anniversaries of the grant date.

SEC source: 0001127602-20-014570 · form4.xml · derivative · entry 3

SOBECKI CHRISTOPHER J · CIK 0001053892 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,638

Underlying: Common Stock · 10,638 shares

Expires not disclosed

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014570 · form4.xml · derivative · entry 2

SOBECKI CHRISTOPHER J · CIK 0001053892 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,115

Underlying: Common Stock · 18,115 shares

Expires 2030-04-24

F1 · derivative.exercise_date: Option vests with respect to one third of the shares subject to the option on each of the first three anniversaries of the grant date.

SEC source: 0001127602-20-014568 · form4.xml · derivative · entry 3

Palantoni Frank · CIK 0001307963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,638

Underlying: Common Stock · 10,638 shares

Expires not disclosed

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014568 · form4.xml · derivative · entry 2

Palantoni Frank · CIK 0001307963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,115

Underlying: Common Stock · 18,115 shares

Expires 2030-04-24

F1 · derivative.exercise_date: Option vests with respect to one third of the shares subject to the option on each of the first three anniversaries of the grant date.

SEC source: 0001127602-20-014566 · form4.xml · derivative · entry 3

NIES ALAN S · CIK 0001270260 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,638

Underlying: Common Stock · 10,638 shares

Expires not disclosed

F2 · derivative.exercise_date: Restricted stock unit vests with respect to 100% of the shares subject to the restricted stock unit on the first anniversary of the grant date.

F3 · derivative.expiration_date: Each restricted stock unit represents a contingent right to receive one share of common stock.

SEC source: 0001127602-20-014566 · form4.xml · derivative · entry 2

NIES ALAN S · CIK 0001270260 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,115

Underlying: Common Stock · 18,115 shares

Expires 2030-04-24

F1 · derivative.exercise_date: Option vests with respect to one third of the shares subject to the option on each of the first three anniversaries of the grant date.