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Nasdaq · USD

KYMR

Kymera Therapeutics, Inc.

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Tapewire entity
3545
SEC CIK
0001815442
Parsed reports
296

Last 12 months

Inside the activity.

2 purchase rows · 274 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 2025229
Jan 202603
Feb 202607
Mar 2026037
Apr 2026022
May 202608
Jun 20260152
Jul 202607
Aug 202600
Sep 202603
Oct 202606

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
April 09, 2026 Filed Apr 10, 2026 20:45 UTC
Goodman NoahChief Business Officer
Exercise / conversionCommon Stock 2,500 $21.05 $52,625.00
Disclosure

SEC source: 0001193125-26-151393 · ownership.xml · nonDerivative · entry 1

Goodman Noah · CIK 0002060075 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,806.438

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 23:00 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 4,600 $0.00 Strike: $14.18 $0.00
Disclosure

SEC source: 0001193125-26-138372 · ownership.xml · derivative · entry 7

Ridloff Elena · CIK 0001772518 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,600 shares

Expires 2032-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 11, 2025 adopted by the reporting person.

F4 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 23:00 UTC SaleCommon Stock 1,200 $86.05 $103,260.00
Disclosure

SEC source: 0001193125-26-138372 · ownership.xml · nonDerivative · entry 5

Ridloff Elena · CIK 0001772518 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 11, 2025 adopted by the reporting person.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 23:00 UTC SaleCommon Stock 3,400 $85.19 $289,661.64
Disclosure

SEC source: 0001193125-26-138372 · ownership.xml · nonDerivative · entry 4

Ridloff Elena · CIK 0001772518 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,200

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 11, 2025 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.00 to $85.97, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 23:00 UTC Exercise / conversionCommon Stock 4,600 $14.18 $65,228.00
Disclosure

SEC source: 0001193125-26-138372 · ownership.xml · nonDerivative · entry 3

Ridloff Elena · CIK 0001772518 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,600

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 11, 2025 adopted by the reporting person.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 14,640 $0.00 Strike: $29.64 $0.00
Disclosure

SEC source: 0001193125-26-138371 · ownership.xml · derivative · entry 7

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,633

Underlying: Common Stock · 14,640 shares

Expires 2033-05-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F4 · derivative.exercise_date: Twenty-five percent (25%) of the shares underlying this stock option vested on May 22, 2024 and the remaining shares shall vest in equal monthly installments over the remaining thirty-six (36) months, subject to the reporting person's continued employment through each vesting date.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 1,100 $86.05 $94,655.00
Disclosure

SEC source: 0001193125-26-138371 · ownership.xml · nonDerivative · entry 5

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,202

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 13,540 $85.41 $1,156,510.98
Disclosure

SEC source: 0001193125-26-138371 · ownership.xml · nonDerivative · entry 4

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 62,302

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.00 to $85.97, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionCommon Stock 14,640 $29.64 $433,929.60
Disclosure

SEC source: 0001193125-26-138371 · ownership.xml · nonDerivative · entry 3

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 75,842

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

Read SEC document
March 31, 2026 Filed Apr 1, 2026 23:00 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 7,400 $0.00 Strike: $14.18 $0.00
Disclosure

SEC source: 0001193125-26-138372 · ownership.xml · derivative · entry 6

Ridloff Elena · CIK 0001772518 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 4,600

Underlying: Common Stock · 7,400 shares

Expires 2032-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 11, 2025 adopted by the reporting person.

F4 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
March 31, 2026 Filed Apr 1, 2026 23:00 UTC SaleCommon Stock 7,400 $85.37 $631,738.74
Disclosure

SEC source: 0001193125-26-138372 · ownership.xml · nonDerivative · entry 2

Ridloff Elena · CIK 0001772518 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 11, 2025 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.04 to $85.64, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 31, 2026 Filed Apr 1, 2026 23:00 UTC Exercise / conversionCommon Stock 7,400 $14.18 $104,932.00
Disclosure

SEC source: 0001193125-26-138372 · ownership.xml · nonDerivative · entry 1

Ridloff Elena · CIK 0001772518 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,400

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 11, 2025 adopted by the reporting person.

Read SEC document
March 31, 2026 Filed Apr 1, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 7,600 $0.00 Strike: $29.64 $0.00
Disclosure

SEC source: 0001193125-26-138371 · ownership.xml · derivative · entry 6

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 83,273

Underlying: Common Stock · 7,600 shares

Expires 2033-05-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F4 · derivative.exercise_date: Twenty-five percent (25%) of the shares underlying this stock option vested on May 22, 2024 and the remaining shares shall vest in equal monthly installments over the remaining thirty-six (36) months, subject to the reporting person's continued employment through each vesting date.

Read SEC document
March 31, 2026 Filed Apr 1, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 7,600 $85.38 $648,881.92
Disclosure

SEC source: 0001193125-26-138371 · ownership.xml · nonDerivative · entry 2

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,202

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.02 to $85.60, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 31, 2026 Filed Apr 1, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionCommon Stock 7,600 $29.64 $225,264.00
Disclosure

SEC source: 0001193125-26-138371 · ownership.xml · nonDerivative · entry 1

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,802

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

Read SEC document
March 25, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 24,727 $0.00 Strike: $29.64 $0.00
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · derivative · entry 10

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 90,873

Underlying: Common Stock · 24,727 shares

Expires 2033-05-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F7 · derivative.exercise_date: Twenty-five percent (25%) of the shares underlying this stock option vested on May 22, 2024 and the remaining shares shall vest in equal monthly installments over the remaining thirty-six (36) months, subject to the reporting person's continued employment through each vesting date.

Read SEC document
March 25, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 24,727 $80.26 $1,984,554.40
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · nonDerivative · entry 8

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,202

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $80.00 to $80.86, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 25, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionCommon Stock 24,727 $29.64 $732,908.28
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · nonDerivative · entry 7

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 85,929

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

Read SEC document
March 23, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 84,400 $0.00 Strike: $29.64 $0.00
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · derivative · entry 9

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 115,600

Underlying: Common Stock · 84,400 shares

Expires 2033-05-22

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F7 · derivative.exercise_date: Twenty-five percent (25%) of the shares underlying this stock option vested on May 22, 2024 and the remaining shares shall vest in equal monthly installments over the remaining thirty-six (36) months, subject to the reporting person's continued employment through each vesting date.

Read SEC document
March 23, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 1,200 $80.05 $96,060.00
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · nonDerivative · entry 6

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,202

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

Read SEC document
March 23, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 6,105 $79.87 $487,608.79
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · nonDerivative · entry 5

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 62,402

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $79.01 to $80.00, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 23, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 8,214 $78.40 $643,950.49
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · nonDerivative · entry 4

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,507

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $77.98 to $78.91, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 23, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 52,975 $77.21 $4,089,982.55
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · nonDerivative · entry 3

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 76,721

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $76.95 to $77.93, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 23, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 22,756 $76.73 $1,746,133.87
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · nonDerivative · entry 2

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 129,696

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $75.96 to $76,94, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 23, 2026 Filed Mar 25, 2026 21:15 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionCommon Stock 84,400 $29.64 $2,501,616.00
Disclosure

SEC source: 0001193125-26-124367 · ownership.xml · nonDerivative · entry 1

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 152,452

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

Read SEC document
March 20, 2026 Filed Mar 20, 2026 22:30 UTC Exercise / conversionStock Option (Right to Buy) · Derivative 2,500 $0.00 Strike: $49.10 $0.00
Disclosure

SEC source: 0001193125-26-118032 · ownership.xml · derivative · entry 5

Esposito Pamela · CIK 0001744425 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,500 shares

Expires 2031-06-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 17, 2025 adopted by the reporting person.

F5 · derivative.exercise_date: The shares underlying this stock option are fully vested and exercisable.

Read SEC document
March 20, 2026 Filed Mar 20, 2026 22:30 UTC SaleCommon Stock 1,200 $79.94 $95,933.04
Disclosure

SEC source: 0001193125-26-118032 · ownership.xml · nonDerivative · entry 4

Esposito Pamela · CIK 0001744425 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 17, 2025 adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $79.73 to $80.27, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 20, 2026 Filed Mar 20, 2026 22:30 UTC SaleCommon Stock 600 $79.24 $47,546.34
Disclosure

SEC source: 0001193125-26-118032 · ownership.xml · nonDerivative · entry 3

Esposito Pamela · CIK 0001744425 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,200

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 17, 2025 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $78.70 to $79.63, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 20, 2026 Filed Mar 20, 2026 22:30 UTC SaleCommon Stock 700 $77.71 $54,397.77
Disclosure

SEC source: 0001193125-26-118032 · ownership.xml · nonDerivative · entry 2

Esposito Pamela · CIK 0001744425 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 1,800

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 17, 2025 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $77.46 to $77.98, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range.

Read SEC document
March 20, 2026 Filed Mar 20, 2026 22:30 UTC Exercise / conversionCommon Stock 2,500 $49.10 $122,750.00
Disclosure

SEC source: 0001193125-26-118032 · ownership.xml · nonDerivative · entry 1

Esposito Pamela · CIK 0001744425 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 2,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated September 17, 2025 adopted by the reporting person.

Read SEC document
March 11, 2026 Filed Mar 11, 2026 22:51 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionStock Option (Right to Buy) · Derivative 20,000 $0.00 Strike: $43.50 $0.00
Disclosure

SEC source: 0001193125-26-102630 · ownership.xml · derivative · entry 5

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 60,548

Underlying: Common Stock · 20,000 shares

Expires 2034-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F5 · derivative.exercise_date: The shares underlying this stock option shall vest in thirty-six (36) equal monthly installments following March 1, 2024, subject to the reporting person's continued employment through each vesting date.

Read SEC document
March 11, 2026 Filed Mar 11, 2026 22:51 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 11,111 $83.72 $930,207.36
Disclosure

SEC source: 0001193125-26-102630 · ownership.xml · nonDerivative · entry 4

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 68,052

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $83.47 to $84.21, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 11, 2026 Filed Mar 11, 2026 22:51 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 12,882 $83.10 $1,070,510.95
Disclosure

SEC source: 0001193125-26-102630 · ownership.xml · nonDerivative · entry 3

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 79,163

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $82.47 to $83.46, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 11, 2026 Filed Mar 11, 2026 22:51 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 1,765 $82.13 $144,955.04
Disclosure

SEC source: 0001193125-26-102630 · ownership.xml · nonDerivative · entry 2

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 92,045

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $81.47 to $82.46, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 11, 2026 Filed Mar 11, 2026 22:51 UTC
Chadwick Jeremy GChief Operating Officer
Exercise / conversionCommon Stock 20,000 $43.50 $870,000.00
Disclosure

SEC source: 0001193125-26-102630 · ownership.xml · nonDerivative · entry 1

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 93,810

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These transactions were effected pursuant to a Rule 10b5-1 trading plan dated December 10, 2025 adopted by the reporting person.

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March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 358 $86.62 $31,011.64
Disclosure

SEC source: 0001193125-26-091985 · ownership.xml · nonDerivative · entry 8

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 73,810

F3 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $86.48 to $86.97, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 1,150 $85.78 $98,647.81
Disclosure

SEC source: 0001193125-26-091985 · ownership.xml · nonDerivative · entry 7

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,168

F3 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.45 to $86.43, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 2,017 $85.04 $171,518.42
Disclosure

SEC source: 0001193125-26-091985 · ownership.xml · nonDerivative · entry 6

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,318

F3 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $84.4475 to $85.44, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Chadwick Jeremy GChief Operating Officer
SaleCommon Stock 394 $84.00 $33,094.62
Disclosure

SEC source: 0001193125-26-091985 · ownership.xml · nonDerivative · entry 5

Chadwick Jeremy G · CIK 0001388406 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 77,335

F3 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $83.36 to $84.3338, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Gollob JaredChief Medical Officer
SaleCommon Stock 447 $86.62 $38,721.24
Disclosure

SEC source: 0001193125-26-091983 · ownership.xml · nonDerivative · entry 8

Gollob Jared · CIK 0001821198 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 117,134

F2 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $86.48 to $86.97, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Gollob JaredChief Medical Officer
SaleCommon Stock 1,437 $85.78 $123,266.87
Disclosure

SEC source: 0001193125-26-091983 · ownership.xml · nonDerivative · entry 7

Gollob Jared · CIK 0001821198 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 117,581

F2 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.45 to $86.43, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Gollob JaredChief Medical Officer
SaleCommon Stock 2,519 $85.04 $214,206.69
Disclosure

SEC source: 0001193125-26-091983 · ownership.xml · nonDerivative · entry 6

Gollob Jared · CIK 0001821198 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 119,018

F2 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $84.4475 to $85.44, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Gollob JaredChief Medical Officer
SaleCommon Stock 492 $84.00 $41,326.28
Disclosure

SEC source: 0001193125-26-091983 · ownership.xml · nonDerivative · entry 5

Gollob Jared · CIK 0001821198 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 121,537

F2 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $83.36 to $84.3338, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Jacobs Bruce N.Chief Financial Officer
SaleCommon Stock 447 $86.62 $38,721.24
Disclosure

SEC source: 0001193125-26-091982 · ownership.xml · nonDerivative · entry 8

Jacobs Bruce N. · CIK 0001821074 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 232,588

F2 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $86.48 to $86.97, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Jacobs Bruce N.Chief Financial Officer
SaleCommon Stock 1,437 $85.78 $123,266.87
Disclosure

SEC source: 0001193125-26-091982 · ownership.xml · nonDerivative · entry 7

Jacobs Bruce N. · CIK 0001821074 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 233,035

F2 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.45 to $86.43, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Jacobs Bruce N.Chief Financial Officer
SaleCommon Stock 2,519 $85.04 $214,206.69
Disclosure

SEC source: 0001193125-26-091982 · ownership.xml · nonDerivative · entry 6

Jacobs Bruce N. · CIK 0001821074 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 234,472

F2 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $84.4475 to $85.44, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Read SEC document
March 04, 2026 Filed Mar 4, 2026 23:00 UTC
Jacobs Bruce N.Chief Financial Officer
SaleCommon Stock 492 $84.00 $41,326.28
Disclosure

SEC source: 0001193125-26-091982 · ownership.xml · nonDerivative · entry 5

Jacobs Bruce N. · CIK 0001821074 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 236,991

F2 · kind: Represents shares required to be sold by the reporting person to cover tax withholding obligations in connection with the vesting of RSUs. Such sales were automatic and not in the discretion of the reporting person.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $83.36 to $84.3338, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

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March 02, 2026 Filed Mar 4, 2026 23:00 UTC
Mainolfi NelloDirector · Chief Executive Officer
GrantStock Option (Right to Buy) · Derivative 215,000 $0.00 Strike: $90.10 $0.00
Disclosure

SEC source: 0001193125-26-091980 · ownership.xml · derivative · entry 1

Mainolfi Nello · CIK 0001821189 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 215,000

Underlying: Common Stock · 215,000 shares

Expires 2036-03-01

F1 · derivative.exercise_date: The shares underlying this stock option shall vest in forty-eight (48) equal monthly installments following March 2, 2026, subject to the reporting person's continued employment through each vesting date.

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March 02, 2026 Filed Mar 4, 2026 23:00 UTC
Adams BrianChief Legal Officer
GrantStock Option (Right to Buy) · Derivative 8,250 $0.00 Strike: $90.10 $0.00
Disclosure

SEC source: 0001193125-26-091986 · ownership.xml · derivative · entry 2

Adams Brian · CIK 0001636994 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,250

Underlying: Common Stock · 8,250 shares

Expires 2036-03-01

F2 · derivative.exercise_date: The shares underlying this stock option shall vest in fourty-eight (48) equal monthly installments following March 2, 2026, subject to the reporting person's continued employment through each vesting date.

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March 02, 2026 Filed Mar 4, 2026 23:00 UTC
Adams BrianChief Legal Officer
GrantCommon Stock 4,125 $0.00 $0.00
Disclosure

SEC source: 0001193125-26-091986 · ownership.xml · nonDerivative · entry 1

Adams Brian · CIK 0001636994 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,625

F1 · shares: Represents restricted stock units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's common stock upon vesting and settlement. The RSUs shall vest in four equal annual installments following March 2, 2026, subject to the reporting person's continued employment through each vesting date.

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.