KRRO

SEC source: 0001193125-26-104719 · ownership.xml · nonDerivative · entry 1

New Enterprise Associates 17, L.P. · CIK 0001768564 · 10% owner

NEA Partners 17, L.P. · CIK 0001796820 · 10% owner

NEA 17 GP, LLC · CIK 0001796821 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.direct: The securities are directly held by New Enterprise Associates 17, L.P. ("NEA 17") and are indirectly held by NEA Partners 17, L.P. ("NEA Partners 17"), the sole general partner of NEA 17, NEA 17 GP, LLC ("NEA 17 GP"), the sole general partner of NEA Partners 17, and the individual managers of NEA 17 GP (NEA Partners 17, NEA 17 GP and the individual managers of NEA 17 GP (collectively, the "Managers") together, the "Indirect Reporting Persons"). The Mangers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony Florence, Jr., Mohamad Makhzoumi, Edward Mathers, Scott Sandell, Paul Walker and Rick Yang. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Indirect Reporting Persons have no pecuniary interest.

SEC source: 0001193125-26-104720 · ownership.xml · derivative · entry 2

SANDELL SCOTT D · CIK 0001237289 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 242,945

Underlying: Common Stock · 242,945 shares

Expires not disclosed

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F3 · derivative.exercise_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F3 · derivative.expiration_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104720 · ownership.xml · nonDerivative · entry 1

SANDELL SCOTT D · CIK 0001237289 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104716 · ownership.xml · derivative · entry 2

BASKETT FOREST · CIK 0001277631 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 242,945

Underlying: Common Stock · 242,945 shares

Expires not disclosed

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F3 · derivative.exercise_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F3 · derivative.expiration_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104716 · ownership.xml · nonDerivative · entry 1

BASKETT FOREST · CIK 0001277631 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104715 · ownership.xml · derivative · entry 2

Mathers Edward T · CIK 0001328625 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 242,945

Underlying: Common Stock · 242,945 shares

Expires not disclosed

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F3 · derivative.exercise_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F3 · derivative.expiration_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104715 · ownership.xml · nonDerivative · entry 1

Mathers Edward T · CIK 0001328625 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104714 · ownership.xml · derivative · entry 2

Walker Paul Edward · CIK 0001553150 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 242,945

Underlying: Common Stock · 242,945 shares

Expires not disclosed

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F3 · derivative.exercise_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F3 · derivative.expiration_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104714 · ownership.xml · nonDerivative · entry 1

Walker Paul Edward · CIK 0001553150 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104712 · ownership.xml · derivative · entry 2

Florence Anthony A. Jr. · CIK 0001559827 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 242,945

Underlying: Common Stock · 242,945 shares

Expires not disclosed

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F3 · derivative.exercise_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F3 · derivative.expiration_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104712 · ownership.xml · nonDerivative · entry 1

Florence Anthony A. Jr. · CIK 0001559827 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104718 · ownership.xml · derivative · entry 2

Behbahani Ali · CIK 0001613867 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 242,945

Underlying: Common Stock · 242,945 shares

Expires not disclosed

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F3 · derivative.exercise_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F3 · derivative.expiration_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104718 · ownership.xml · nonDerivative · entry 1

Behbahani Ali · CIK 0001613867 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104713 · ownership.xml · derivative · entry 2

Makhzoumi Mohamad · CIK 0001630226 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 242,945

Underlying: Common Stock · 242,945 shares

Expires not disclosed

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F3 · derivative.exercise_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F3 · derivative.expiration_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104713 · ownership.xml · nonDerivative · entry 1

Makhzoumi Mohamad · CIK 0001630226 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104717 · ownership.xml · derivative · entry 2

Chang Carmen · CIK 0001746342 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 242,945

Underlying: Common Stock · 242,945 shares

Expires not disclosed

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F3 · derivative.exercise_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F3 · derivative.expiration_date: The Pre-Funded Warrants are exercisable at any time after their issuance; provided, however, that the Pre-Funded Warrants may not be exercised to the extent such exercise would cause the number of shares of the Issuer's Common Stock owned by the holder (together with its affiliates and certain other related parties) to exceed 9.99% of the total number of shares of the Issuer's Common Stock immediately after giving effect to such exercise, which percentage may be increased or decreased at the option of the holder upon 61 days' prior notice to the Issuer, not to exceed 19.99%.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-104717 · ownership.xml · nonDerivative · entry 1

Chang Carmen · CIK 0001746342 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See Note 2

Disclosed balance after: 1,297,893

F1 · kind: Acquired from the Issuer on March 10, 2026 pursuant to a Subscription Agreement dated March 9, 2026.

F2 · ownership.nature: The Reporting Person is a manager of NEA 17 GP, LLC, which is the sole general partner of NEA Partners 17, L.P. ("NEA Partners 17"). NEA Partners 17 is the sole general partner of New Enterprise Associates 17, L.P. ("NEA 17"), the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 17 in which the Reporting Person has no pecuniary interest.

SEC source: 0001193125-26-035541 · ownership.xml · derivative · entry 1

Dolan Oliver · CIK 0002053835 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2036-02-01

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-26-035518 · ownership.xml · derivative · entry 1

Cerio Jeffrey · CIK 0002033618 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,000

Underlying: Common Stock · 23,000 shares

Expires 2036-02-01

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-26-035591 · ownership.xml · derivative · entry 3

Aiyar Ram · CIK 0001997920 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 80,000

Underlying: Common Stock · 80,000 shares

Expires 2036-02-01

F3 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-26-035591 · ownership.xml · nonDerivative · entry 1

Aiyar Ram · CIK 0001997920 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

F1 · shares: Represents shares of common stock issuable upon settlement of a restricted stock unit (RSU) granted under the Issuer's 2023 Stock Option and Incentive Plan (the 2023 Plan) that will vest as follows: 50% on August 3, 2026 and 50% on February 1, 2027, in each case subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-26-035564 · ownership.xml · derivative · entry 1

Vincent Loic A · CIK 0002063400 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2036-02-01

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-26-035481 · ownership.xml · derivative · entry 1

Chappell Todd · CIK 0001997992 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 38,000

Underlying: Common Stock · 38,000 shares

Expires 2036-02-01

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001193125-25-320841 · ownership.xml · nonDerivative · entry 1

Dolan Oliver · CIK 0002053835 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,482

F1 · security: Represents shares of common stock issuable upon settlement of a restricted stock unit (RSU) granted under the Issuer's 2023 Stock Option and Incentive Plan (the 2023 Plan) that will vest as follows: 50% on June 15, 2026 and 50% on December 15, 2026, in each case subject to the reporting person maintaining a continuous Service Relationship (as defined in the 2023 Plan) through each such date.

SEC source: 0001193125-25-320851 · ownership.xml · nonDerivative · entry 1

Cerio Jeffrey · CIK 0002033618 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,902

F1 · security: Represents shares of common stock issuable upon settlement of a restricted stock unit (RSU) granted under the Issuer's 2023 Stock Option and Incentive Plan (the 2023 Plan) that will vest as follows: 50% on June 15, 2026 and 50% on December 15, 2026, in each case subject to the reporting person maintaining a continuous Service Relationship (as defined in the 2023 Plan) through each such date.

SEC source: 0001193125-25-320864 · ownership.xml · nonDerivative · entry 1

Chappell Todd · CIK 0001997992 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,132

F1 · security: Represents shares of common stock issuable upon settlement of a restricted stock unit (RSU) granted under the Issuer's 2023 Stock Option and Incentive Plan (the 2023 Plan) that will vest as follows: 50% on June 15, 2026 and 50% on December 15, 2026, in each case subject to the reporting person maintaining a continuous Service Relationship (as defined in the 2023 Plan) through each such date.

SEC source: 0001193125-25-320859 · ownership.xml · nonDerivative · entry 1

Vincent Loic A · CIK 0002063400 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,715

F1 · security: Represents shares of common stock issuable upon settlement of a restricted stock unit (RSU) granted under the Issuer's 2023 Stock Option and Incentive Plan (the 2023 Plan) that will vest as follows: 50% on June 15, 2026 and 50% on December 15, 2026, in each case subject to the reporting person maintaining a continuous Service Relationship (as defined in the 2023 Plan) through each such date.

SEC source: 0000950170-25-085424 · ownership.xml · derivative · entry 1

FORMELA JEAN FRANCOIS · CIK 0001030575 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,010

Underlying: Common Stock · 6,010 shares

Expires 2035-06-10

F1 · derivative.exercise_date: The shares subject to the option vest in full on the earlier of (i) the one-year anniversary of the grant date or (ii) the date of the next annual meeting of stockholders, subject to continued service as a non-employee director through the applicable vesting date.

SEC source: 0000950170-25-085480 · ownership.xml · derivative · entry 1

Meyers Rachel · CIK 0002001472 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,010

Underlying: Common Stock · 6,010 shares

Expires 2035-06-10

F1 · derivative.exercise_date: The shares subject to the option vest in full on the earlier of (i) the one-year anniversary of the grant date or (ii) the date of the next annual meeting of stockholders, subject to continued service as a non-employee director through the applicable vesting date.

SEC source: 0000950170-25-085455 · ownership.xml · derivative · entry 1

Bermingham Nessan · CIK 0001377759 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,010

Underlying: Common Stock · 6,010 shares

Expires 2035-06-10

F1 · derivative.exercise_date: The shares subject to the option vest in full on the earlier of (i) the one-year anniversary of the grant date or (ii) the date of the next annual meeting of stockholders, subject to continued service as a non-employee director through the applicable vesting date.

SEC source: 0000950170-25-085411 · ownership.xml · derivative · entry 1

PEARSON TIMOTHY R · CIK 0001528617 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,010

Underlying: Common Stock · 6,010 shares

Expires 2035-06-10

F1 · derivative.exercise_date: The shares subject to the option vest in full on the earlier of (i) the one-year anniversary of the grant date or (ii) the date of the next annual meeting of stockholders, subject to continued service as a non-employee director through the applicable vesting date.

SEC source: 0000950170-25-085495 · ownership.xml · derivative · entry 1

Behbahani Ali · CIK 0001613867 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,010

Underlying: Common Stock · 6,010 shares

Expires 2035-06-10

F1 · derivative.exercise_date: The shares subject to the option vest in full on the earlier of (i) the one-year anniversary of the grant date or (ii) the date of the next annual meeting of stockholders, subject to continued service as a non-employee director through the applicable vesting date.

SEC source: 0000950170-25-085435 · ownership.xml · derivative · entry 1

Knobil Katharine · CIK 0001768011 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,010

Underlying: Common Stock · 6,010 shares

Expires 2035-06-10

F1 · derivative.exercise_date: The shares subject to the option vest in full on the earlier of (i) the one-year anniversary of the grant date or (ii) the date of the next annual meeting of stockholders, subject to continued service as a non-employee director through the applicable vesting date.

SEC source: 0000950170-25-048848 · ownership.xml · derivative · entry 1

Dolan Oliver · CIK 0002053835 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 20,000

Underlying: Common Stock · 20,000 shares

Expires 2035-03-26

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from March 27, 2025, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-048847 · ownership.xml · derivative · entry 1

Vincent Loic A · CIK 0002063400 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 70,000

Underlying: Common Stock · 70,000 shares

Expires 2035-03-30

F1 · derivative.exercise_date: The shares subject to the option vest as to 25% of the shares on March 31, 2026, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date

SEC source: 0000950170-25-014574 · ownership.xml · derivative · entry 1

Cerio Jeffrey · CIK 0002033618 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,000

Underlying: Common Stock · 29,000 shares

Expires 2035-02-02

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 3, 2025, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-014478 · ownership.xml · derivative · entry 1

Olugemo Olukemi · CIK 0002022212 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 42,000

Underlying: Common Stock · 42,000 shares

Expires 2035-02-02

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 3, 2025, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-014551 · ownership.xml · derivative · entry 1

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2035-02-02

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 3, 2025, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-014517 · ownership.xml · derivative · entry 1

Aiyar Ram · CIK 0001997920 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2035-02-02

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 3, 2025, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-25-014515 · ownership.xml · derivative · entry 1

Chappell Todd · CIK 0001997992 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,500

Underlying: Common Stock · 34,500 shares

Expires 2035-02-02

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from February 3, 2025, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-24-125822 · ownership.xml · derivative · entry 3

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 30,807

Underlying: Common Stock · 800 shares

Expires 2031-05-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

F2 · derivative.exercise_date: The shares subject to the option vest as to 25% of the shares on May 11, 2022, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-24-125822 · ownership.xml · nonDerivative · entry 2

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

SEC source: 0000950170-24-125822 · ownership.xml · nonDerivative · entry 1

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 800

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

SEC source: 0000950170-24-115723 · ownership.xml · derivative · entry 15

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 45,594

Underlying: Common Stock · 953 shares

Expires 2033-11-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

F11 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments commencing from November 3, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-24-115723 · ownership.xml · derivative · entry 14

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,607

Underlying: Common Stock · 9,263 shares

Expires 2031-05-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

F10 · derivative.exercise_date: The shares subject to the option vest as to 25% of the shares on May 11, 2022, with the remainder vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0000950170-24-115723 · ownership.xml · nonDerivative · entry 13

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

SEC source: 0000950170-24-115723 · ownership.xml · nonDerivative · entry 12

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

F9 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $81.20 to $82.00, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the Issuer, any security holder of the Issuer, or the SEC staff upon request.

SEC source: 0000950170-24-115723 · ownership.xml · nonDerivative · entry 11

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 342

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

F8 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $80.15 to $81.14, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the Issuer, any security holder of the Issuer, or the SEC staff upon request.

SEC source: 0000950170-24-115723 · ownership.xml · nonDerivative · entry 10

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 5,303

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

F7 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $79.12 to $80.115, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the Issuer, any security holder of the Issuer, or the SEC staff upon request.

SEC source: 0000950170-24-115723 · ownership.xml · nonDerivative · entry 9

Agarwal Vineet · CIK 0001997973 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,118

F1 · kind: The reported transactions occurred automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 19, 2024.

F6 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $78.07 to $78.935, inclusive. Full information regarding the number of shares sold at each separate price can be furnished to the Issuer, any security holder of the Issuer, or the SEC staff upon request.