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KPTI

Karyopharm Therapeutics Inc.

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781
SEC CIK
0001503802
Parsed reports
479

Last 12 months

Inside the activity.

0 purchase rows · 20 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202500
Dec 202500
Jan 202602
Feb 202602
Mar 202606
Apr 202601
May 202606
Jun 202600
Jul 202601
Aug 202600
Sep 202601
Oct 202601

Latest available

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
May 21, 2021 Filed May 21, 2021 21:32 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 23,900 $0.00 Strike: $9.42 $0.00
Disclosure

SEC source: 0001209191-21-035025 · doc4.xml · derivative · entry 1

Dolsten Mikael · CIK 0001437590 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,900

Underlying: Common Stock · 23,900 shares

Expires 2031-05-20

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on the earlier of May 21, 2022 or the next annual meeting of stockholders of Karyopharm Therapeutics Inc. (the "Issuer"), provided that the reporting person continues to serve as a director of the Issuer through such date.

Read SEC document
May 21, 2021 Filed May 21, 2021 21:33 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 23,900 $0.00 Strike: $9.42 $0.00
Disclosure

SEC source: 0001209191-21-035026 · doc4.xml · derivative · entry 1

Greene Barry E · CIK 0001291963 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,900

Underlying: Common Stock · 23,900 shares

Expires 2031-05-20

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on the earlier of May 21, 2022 or the next annual meeting of stockholders of Karyopharm Therapeutics Inc. (the "Issuer"), provided that the reporting person continues to serve as a director of the Issuer through such date.

Read SEC document
May 21, 2021 Filed May 21, 2021 21:35 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 23,900 $0.00 Strike: $9.42 $0.00
Disclosure

SEC source: 0001209191-21-035030 · doc4.xml · derivative · entry 1

PAKIANATHAN DEEPIKA · CIK 0001270734 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,900

Underlying: Common Stock · 23,900 shares

Expires 2031-05-20

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on the earlier of May 21, 2022 or the next annual meeting of stockholders of Karyopharm Therapeutics Inc. (the "Issuer"), provided that the reporting person continues to serve as a director of the Issuer through such date.

Read SEC document
May 21, 2021 Filed May 21, 2021 21:31 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 23,900 $0.00 Strike: $9.42 $0.00
Disclosure

SEC source: 0001209191-21-035024 · doc4.xml · derivative · entry 1

BOHLIN GAREN G · CIK 0001254705 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,900

Underlying: Common Stock · 23,900 shares

Expires 2031-05-20

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on the earlier of May 21, 2022 or the next annual meeting of stockholders of Karyopharm Therapeutics Inc. (the "Issuer"), provided that the reporting person continues to serve as a director of the Issuer through such date.

Read SEC document
May 21, 2021 Filed May 21, 2021 21:36 UTC
Schor ChenDirector
GrantNonstatutory Stock Option (right to buy) · Derivative 23,900 $0.00 Strike: $9.42 $0.00
Disclosure

SEC source: 0001209191-21-035031 · doc4.xml · derivative · entry 1

Schor Chen · CIK 0001340875 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,900

Underlying: Common Stock · 23,900 shares

Expires 2031-05-20

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on the earlier of May 21, 2022 or the next annual meeting of stockholders of Karyopharm Therapeutics Inc. (the "Issuer"), provided that the reporting person continues to serve as a director of the Issuer through such date.

Read SEC document
May 21, 2021 Filed May 21, 2021 21:35 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 23,900 $0.00 Strike: $9.42 $0.00
Disclosure

SEC source: 0001209191-21-035028 · doc4.xml · derivative · entry 1

Oliger Christy J. · CIK 0001822092 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,900

Underlying: Common Stock · 23,900 shares

Expires 2031-05-20

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on the earlier of May 21, 2022 or the next annual meeting of stockholders of Karyopharm Therapeutics Inc. (the "Issuer"), provided that the reporting person continues to serve as a director of the Issuer through such date.

Read SEC document
May 21, 2021 Filed May 21, 2021 21:34 UTC GrantNonstatutory Stock Option (right to buy) · Derivative 23,900 $0.00 Strike: $9.42 $0.00
Disclosure

SEC source: 0001209191-21-035027 · doc4.xml · derivative · entry 1

Mirza Mansoor Raza · CIK 0001588389 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,900

Underlying: Common Stock · 23,900 shares

Expires 2031-05-20

F1 · derivative.exercise_date: This option vests as to 100% of the underlying shares on the earlier of May 21, 2022 or the next annual meeting of stockholders of Karyopharm Therapeutics Inc. (the "Issuer"), provided that the reporting person continues to serve as a director of the Issuer through such date.

Read SEC document
May 07, 2021 Filed May 11, 2021 12:58 UTC
Shah JatinEVP, Chief Medical Officer
PurchaseCommon Stock 23,250 $8.60 $199,991.85
Disclosure

SEC source: 0001209191-21-031481 · doc4.xml · nonDerivative · entry 1

Shah Jatin · CIK 0001782186 · EVP, Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,802

F1 · price: Represents the weighted average purchase price. These shares were purchased in multiple transactions at prices ranging from $8.5850 to $8.61, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares purchased at each separate price.

F2 · balance_after: Includes 861 shares acquired by the reporting person under the Karyopharm Therapeutics Inc. 2013 Employee Stock Purchase Plan on April 30, 2021.

Read SEC document
May 06, 2021 Filed May 10, 2021 23:57 UTC PurchaseCommon Stock 4,000 $7.82 $31,280.00
Disclosure

SEC source: 0001209191-21-031437 · doc4.xml · nonDerivative · entry 1

BOHLIN GAREN G · CIK 0001254705 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,000

Read SEC document
May 03, 2021 Filed May 5, 2021 01:06 UTC
Paulson Richard A.Director · President and CEO
GrantStock Option (right to buy) · Derivative 559,800 $0.00 Strike: $9.44 $0.00
Disclosure

SEC source: 0001209191-21-030166 · doc4.xml · derivative · entry 2

Paulson Richard A. · CIK 0001804460 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 559,800

Underlying: Common Stock · 559,800 shares

Expires 2031-05-02

F2 · derivative.exercise_date: This option was granted on May 3, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on May 3, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
May 03, 2021 Filed May 5, 2021 01:06 UTC
Paulson Richard A.Director · President and CEO
GrantCommon Stock 373,200 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-030166 · doc4.xml · nonDerivative · entry 1

Paulson Richard A. · CIK 0001804460 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 373,200

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest as to 25% of the shares on May 3, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
March 18, 2021 Filed Mar 23, 2021 11:48 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 4,000 $12.39 $49,552.80
Disclosure

SEC source: 0001209191-21-022486 · doc4.xml · nonDerivative · entry 1

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 714,826

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $12.29 to $12.56, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
March 18, 2021 Filed Mar 23, 2021 11:50 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 4,000 $12.39 $49,552.80
Disclosure

SEC source: 0001209191-21-022487 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 714,826

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the spouse of the reporting person.

F2 · price: Represents the weighted average sale price. These shares were sold in multiple transactions at prices ranging from $12.29 to $12.56, inclusive. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.

Read SEC document
February 25, 2021 Filed Mar 1, 2021 20:10 UTC
DEMAREE JOHNChief Commercial Officer
GrantStock Option (right to buy) · Derivative 43,177 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015483 · doc4.xml · derivative · entry 2

DEMAREE JOHN · CIK 0001744959 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,177

Underlying: Common Stock · 43,177 shares

Expires 2031-02-24

F3 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 1, 2021 20:10 UTC
DEMAREE JOHNChief Commercial Officer
GrantCommon Stock 15,849 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015483 · doc4.xml · nonDerivative · entry 1

DEMAREE JOHN · CIK 0001744959 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,995

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F2 · balance_after: The reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 15,849 newly awarded RSUs and 8,146 shares of common stock, which include 646 shares acquired under the Karyopharm Therapeutics Inc. 2013 Employee Stock Purchase Plan on October 31, 2020.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:13 UTC
Lewis TanyaEVP, Chief Reg. Affairs
GrantStock Option (right to buy) · Derivative 59,968 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015485 · doc4.xml · derivative · entry 2

Lewis Tanya · CIK 0001451038 · EVP, Chief Reg. Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,968

Underlying: Common Stock · 59,968 shares

Expires 2031-02-24

F3 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:13 UTC
Lewis TanyaEVP, Chief Reg. Affairs
GrantCommon Stock 22,013 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015485 · doc4.xml · nonDerivative · entry 1

Lewis Tanya · CIK 0001451038 · EVP, Chief Reg. Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 45,401

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F2 · balance_after: The reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 22,013 newly awarded RSUs, 19,245 RSUs previously reported in Table II, and 4,143 shares of common stock.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:09 UTC
Kauffman MichaelDirector · Chief Executive Officer
GrantStock Option (right to buy) · Derivative 153,500 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015481 · doc4.xml · derivative · entry 4

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 153,500

Underlying: Common Stock · 153,500 shares

Expires 2031-02-24

F4 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:09 UTC
Kauffman MichaelDirector · Chief Executive Officer
GrantStock Option (right to buy) · Derivative 153,500 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015481 · doc4.xml · derivative · entry 3

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 153,500

Underlying: Common Stock · 153,500 shares

Expires 2031-02-24

F4 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:09 UTC
Kauffman MichaelDirector · Chief Executive Officer
GrantCommon Stock 57,200 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015481 · doc4.xml · nonDerivative · entry 2

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 920,152

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F3 · balance_after: The spouse of the reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 57,200 newly awarded RSUs, 86,500 RSUs previously reported in Table II, and 776,452 shares of common stock.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:09 UTC
Kauffman MichaelDirector · Chief Executive Officer
GrantCommon Stock 57,200 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015481 · doc4.xml · nonDerivative · entry 1

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 718,826

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F2 · balance_after: The reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 57,200 newly awarded RSUs, 86,500 RSUs previously reported in Table II, and 575,126 shares of common stock.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:17 UTC
Shah JatinEVP, Chief Medical Officer
GrantStock Option (right to buy) · Derivative 59,968 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015487 · doc4.xml · derivative · entry 2

Shah Jatin · CIK 0001782186 · EVP, Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,968

Underlying: Common Stock · 59,968 shares

Expires 2031-02-24

F3 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:17 UTC
Shah JatinEVP, Chief Medical Officer
GrantCommon Stock 22,013 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015487 · doc4.xml · nonDerivative · entry 1

Shah Jatin · CIK 0001782186 · EVP, Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 107,691

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F2 · balance_after: The reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 22,013 newly awarded RSUs, 33,887 RSUs previously reported in Table II, and 51,791 shares of common stock.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:16 UTC
Mason MichaelSVP, CFO & Treasurer
GrantStock Option (right to buy) · Derivative 59,968 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015486 · doc4.xml · derivative · entry 2

Mason Michael · CIK 0001514291 · SVP, CFO & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,968

Underlying: Common Stock · 59,968 shares

Expires 2031-02-24

F3 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:16 UTC
Mason MichaelSVP, CFO & Treasurer
GrantCommon Stock 22,013 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015486 · doc4.xml · nonDerivative · entry 1

Mason Michael · CIK 0001514291 · SVP, CFO & Treasurer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,755

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F2 · balance_after: The reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 22,013 newly awarded RSUs, 24,450 RSUs previously reported in Table II, and 5,292 shares of common stock.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:12 UTC
Frenkel RanEVP, Chief Dev. Officer
GrantStock Option (right to buy) · Derivative 59,968 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015484 · doc4.xml · derivative · entry 2

Frenkel Ran · CIK 0001623108 · EVP, Chief Dev. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,968

Underlying: Common Stock · 59,968 shares

Expires 2031-02-24

F3 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:12 UTC
Frenkel RanEVP, Chief Dev. Officer
GrantCommon Stock 22,013 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015484 · doc4.xml · nonDerivative · entry 1

Frenkel Ran · CIK 0001623108 · EVP, Chief Dev. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,439

F1 · shares: Represents the award of Restricted Stock Units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F2 · balance_after: The reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 22,013 newly awarded RSUs, 36,300 RSUs previously reported in Table II, and 46,126 shares of common stock.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:09 UTC
Shacham SharonPresident & CSO
GrantStock Option (right to buy) · Derivative 153,500 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015482 · doc4.xml · derivative · entry 4

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 153,500

Underlying: Common Stock · 153,500 shares

Expires 2031-02-24

F4 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:09 UTC
Shacham SharonPresident & CSO
GrantStock Option (right to buy) · Derivative 153,500 $0.00 Strike: $14.56 $0.00
Disclosure

SEC source: 0001209191-21-015482 · doc4.xml · derivative · entry 3

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 153,500

Underlying: Common Stock · 153,500 shares

Expires 2031-02-24

F4 · derivative.exercise_date: This option was granted on February 25, 2021 pursuant to the Plan. The shares underlying this option vest as to 25% of the shares on February 25, 2022, with the remaining 75% vesting in 36 equal monthly installments thereafter.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:09 UTC
Shacham SharonPresident & CSO
GrantCommon Stock 57,200 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015482 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 718,826

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F3 · balance_after: The spouse of the reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 57,200 newly awarded RSUs, 86,500 RSUs previously reported in Table II, and 575,126 shares of common stock.

Read SEC document
February 25, 2021 Filed Mar 2, 2021 01:09 UTC
Shacham SharonPresident & CSO
GrantCommon Stock 57,200 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-015482 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 920,152

F1 · shares: Represents the award of restricted stock units ("RSUs") pursuant to the Karyopharm Therapeutics Inc. 2013 Stock Incentive Plan (the "Plan"). RSUs convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis. The RSUs vest in four equal annual installments beginning February 25, 2022.

F2 · balance_after: The reporting person has reported prior awards of RSUs in Table II of Form 4. The total reported in Column 5 includes the 57,200 newly awarded RSUs, 86,500 RSUs previously reported in Table II, and 776,452 shares of common stock.

Read SEC document
February 18, 2021 Filed Feb 23, 2021 01:09 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 9,495 $14.83 $140,822.24
Disclosure

SEC source: 0001209191-21-012960 · doc4.xml · nonDerivative · entry 2

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 776,452

F3 · kind: This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the spouse of the reporting person.

F4 · price: The sale price of the spouse of the reporting person's shares represents the weighted average price of all shares sold by a broker on February 18, 2021 on behalf of a group of employees of Karyopharm Therapeutics Inc. to satisfy the payment of withholding tax liability of such employees.

Read SEC document
February 18, 2021 Filed Feb 23, 2021 01:09 UTC
Kauffman MichaelDirector · Chief Executive Officer
SaleCommon Stock 9,495 $14.83 $140,822.24
Disclosure

SEC source: 0001209191-21-012960 · doc4.xml · nonDerivative · entry 1

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 575,126

F1 · kind: This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the reporting person.

F2 · price: The sale price of the reporting person's shares represents the weighted average price of all shares sold by a broker on February 18, 2021 on behalf of a group of employees of Karyopharm Therapeutics Inc. to satisfy the payment of withholding tax liability of such employees.

Read SEC document
February 18, 2021 Filed Feb 23, 2021 01:11 UTC
Frenkel RanEVP, Chief Dev. Officer
SaleCommon Stock 2,887 $14.83 $42,817.67
Disclosure

SEC source: 0001209191-21-012967 · doc4.xml · nonDerivative · entry 1

Frenkel Ran · CIK 0001623108 · EVP, Chief Dev. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,126

F1 · kind: This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the reporting person.

F2 · price: The sale price of the reporting person's shares represents the weighted average price of all shares sold by a broker on February 18, 2021 on behalf of a group of employees of Karyopharm Therapeutics Inc. to satisfy the payment of withholding tax liability of such employees.

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February 18, 2021 Filed Feb 23, 2021 01:12 UTC
Shah JatinEVP, Chief Medical Officer
SaleCommon Stock 1,186 $14.83 $17,589.80
Disclosure

SEC source: 0001209191-21-012968 · doc4.xml · nonDerivative · entry 1

Shah Jatin · CIK 0001782186 · EVP, Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 51,791

F1 · kind: This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the reporting person.

F2 · price: The sale price of the reporting person's shares represents the weighted average price of all shares sold by a broker on February 18, 2021 on behalf of a group of employees of Karyopharm Therapeutics Inc. to satisfy the payment of withholding tax liability of such employees.

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February 18, 2021 Filed Feb 23, 2021 01:10 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 9,495 $14.83 $140,822.24
Disclosure

SEC source: 0001209191-21-012964 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 575,126

F3 · kind: This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the spouse of the reporting person.

F4 · price: The sale price of the spouse of the reporting person's shares represents the weighted average price of all shares sold by a broker on February 18, 2021 on behalf of a group of employees of Karyopharm Therapeutics Inc. to satisfy the payment of withholding tax liability of such employees.

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February 18, 2021 Filed Feb 23, 2021 01:10 UTC
Shacham SharonPresident & CSO
SaleCommon Stock 9,495 $14.83 $140,822.24
Disclosure

SEC source: 0001209191-21-012964 · doc4.xml · nonDerivative · entry 1

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 776,452

F1 · kind: This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the reporting person.

F2 · price: The sale price of the reporting person's shares represents the weighted average price of all shares sold by a broker on February 18, 2021 on behalf of a group of employees of Karyopharm Therapeutics Inc. to satisfy the payment of withholding tax liability of such employees.

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February 15, 2021 Filed Feb 17, 2021 23:44 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionRestricted Stock Units · Derivative 21,800 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-011484 · doc4.xml · derivative · entry 6

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 43,600

Underlying: Common Stock · 21,800 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

F7 · derivative.exercise_date: On February 15, 2019, the spouse of the reporting person was granted 87,200 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the spouse of the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

F7 · derivative.expiration_date: On February 15, 2019, the spouse of the reporting person was granted 87,200 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the spouse of the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:44 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionRestricted Stock Units · Derivative 21,800 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-011484 · doc4.xml · derivative · entry 5

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,600

Underlying: Common Stock · 21,800 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

F6 · derivative.exercise_date: On February 15, 2019, the reporting person was granted 87,200 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

F6 · derivative.expiration_date: On February 15, 2019, the reporting person was granted 87,200 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:44 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionCommon Stock 21,800 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-21-011484 · doc4.xml · nonDerivative · entry 4

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 785,947

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:44 UTC
Kauffman MichaelDirector · Chief Executive Officer
Exercise / conversionCommon Stock 21,800 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-21-011484 · doc4.xml · nonDerivative · entry 2

Kauffman Michael · CIK 0001364719 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 584,621

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:48 UTC
Shah JatinEVP, Chief Medical Officer
Exercise / conversionRestricted Stock Units · Derivative 4,850 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-011494 · doc4.xml · derivative · entry 3

Shah Jatin · CIK 0001782186 · EVP, Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,700

Underlying: Common Stock · 4,850 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

F4 · derivative.exercise_date: On February 15, 2019, the reporting person was granted 19,400 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

F4 · derivative.expiration_date: On February 15, 2019, the reporting person was granted 19,400 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:48 UTC
Shah JatinEVP, Chief Medical Officer
Exercise / conversionCommon Stock 4,850 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-21-011494 · doc4.xml · nonDerivative · entry 2

Shah Jatin · CIK 0001782186 · EVP, Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,977

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:47 UTC
Frenkel RanEVP, Chief Dev. Officer
Exercise / conversionRestricted Stock Units · Derivative 9,675 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-011490 · doc4.xml · derivative · entry 3

Frenkel Ran · CIK 0001623108 · EVP, Chief Dev. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,350

Underlying: Common Stock · 9,675 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

F4 · derivative.exercise_date: On February 15, 2019, the reporting person was granted 38,700 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

F4 · derivative.expiration_date: On February 15, 2019, the reporting person was granted 38,700 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:47 UTC
Frenkel RanEVP, Chief Dev. Officer
Exercise / conversionCommon Stock 9,675 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-21-011490 · doc4.xml · nonDerivative · entry 2

Frenkel Ran · CIK 0001623108 · EVP, Chief Dev. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,013

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:45 UTC
Shacham SharonPresident & CSO
Exercise / conversionRestricted Stock Units · Derivative 21,800 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-011486 · doc4.xml · derivative · entry 6

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 43,600

Underlying: Common Stock · 21,800 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

F7 · derivative.exercise_date: On February 15, 2019, the spouse of the reporting person was granted 87,200 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the spouse of the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

F7 · derivative.expiration_date: On February 15, 2019, the spouse of the reporting person was granted 87,200 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the spouse of the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:45 UTC
Shacham SharonPresident & CSO
Exercise / conversionRestricted Stock Units · Derivative 21,800 $0.00 $0.00
Disclosure

SEC source: 0001209191-21-011486 · doc4.xml · derivative · entry 5

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,600

Underlying: Common Stock · 21,800 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

F6 · derivative.exercise_date: On February 15, 2019, the reporting person was granted 87,200 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

F6 · derivative.expiration_date: On February 15, 2019, the reporting person was granted 87,200 restricted stock units, vesting in four equal annual installments beginning on the first anniversary of the grant date. 25% of the restricted stock units vested on February 15, 2021. Vested shares will be delivered to the reporting person as soon as practicable following the vesting date, but in any event within 30 days of such date.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:45 UTC
Shacham SharonPresident & CSO
Exercise / conversionCommon Stock 21,800 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-21-011486 · doc4.xml · nonDerivative · entry 4

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Indirect · By Spouse

Disclosed balance after: 584,621

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

Read SEC document
February 15, 2021 Filed Feb 17, 2021 23:45 UTC
Shacham SharonPresident & CSO
Exercise / conversionCommon Stock 21,800 Not disclosed Not disclosed
Disclosure

SEC source: 0001209191-21-011486 · doc4.xml · nonDerivative · entry 2

Shacham Sharon · CIK 0001588438 · President & CSO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 785,947

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · price: Restricted stock units convert into Karyopharm Therapeutics Inc. common stock on a one-for-one basis.

Read SEC document
February 11, 2021 Filed Feb 17, 2021 23:49 UTC
Lewis TanyaEVP, Chief Reg. Affairs
SaleCommon Stock 2,046 $15.52 $31,752.08
Disclosure

SEC source: 0001209191-21-011496 · doc4.xml · nonDerivative · entry 1

Lewis Tanya · CIK 0001451038 · EVP, Chief Reg. Affairs

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,143

F1 · kind: This transaction was a broker-assisted sale of shares to satisfy the payment of withholding tax liability incurred upon the vesting of restricted stock units and does not represent a discretionary trade by the reporting person.

F2 · price: The sale price of the reporting person's shares represents the weighted average price of all shares sold by a broker on February 11, 2021 on behalf of a group of employees of Karyopharm Therapeutics Inc. to satisfy the payment of withholding tax liability of such employees.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.