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JANX

Janux Therapeutics, Inc.

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4864
SEC CIK
0001817713
Parsed reports
166

Last 12 months

Inside the activity.

0 purchase rows · 11 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
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MonthPurchasesSales
Nov 202501
Dec 202502
Jan 202606
Feb 202600
Mar 202600
Apr 202600
May 202601
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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
October 16, 2024 Filed Oct 18, 2024 22:51 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 4,968 $17.00 $84,456.00
Disclosure

SEC source: 0001415889-24-025436 · form4-10182024_101021.xml · nonDerivative · entry 7

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,855

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
October 16, 2024 Filed Oct 18, 2024 22:51 UTC
Lichter Jay10% owner
SaleCommon Stock 30,094 $50.61 $1,523,057.34
Disclosure

SEC source: 0001415889-24-025436 · form4-10182024_101021.xml · nonDerivative · entry 6

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures SPV I, LP

Disclosed balance after: 2,789,272

F5 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $50.46 to $51.25 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F4 · ownership.nature: The securities are directly held by Avalon BioVentures SPV I, LP ("ABV SPV"). ABV SPV I GP LLC ("ABV SPV GP") is the general partner of ABV SPV and may be deemed to beneficially own the securities held by ABV SPV. Mr. Lichter is a managing member of ABV SPV GP and shares voting and investment power with respect to the securities held by ABV SPV. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 16, 2024 Filed Oct 18, 2024 22:51 UTC
Lichter Jay10% owner
SaleCommon Stock 5,710 $50.61 $288,983.10
Disclosure

SEC source: 0001415889-24-025436 · form4-10182024_101021.xml · nonDerivative · entry 5

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures I, LP

Disclosed balance after: 529,173

F5 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $50.46 to $51.25 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The securities are directly held by Avalon BioVentures I, LP ("ABV I"). Avalon BioVentures GP LLC ("ABV GP") is the general partner of ABV I and may be deemed to beneficially own the securities held by ABV I. Mr. Lichter is a managing member of ABV GP and shares voting and investment power with respect to the securities held by ABV I. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 16, 2024 Filed Oct 18, 2024 22:51 UTC
Lichter Jay10% owner
SaleCommon Stock 29,474 $50.61 $1,491,679.14
Disclosure

SEC source: 0001415889-24-025436 · form4-10182024_101021.xml · nonDerivative · entry 4

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,731,817

F5 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $50.46 to $51.25 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F2 · ownership.direct: The securities are directly held by Avalon Ventures XI, L.P. ("Avalon Ventures"). Avalon Ventures XI GP, LLC ("Avalon XI GP") is the general partner of Avalon Ventures and may be deemed to beneficially own the securities held by Avalon Ventures. Mr. Lichter is a managing member of Avalon XI GP and shares voting and investment power with respect to the securities held by Avalon Ventures. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 16, 2024 Filed Oct 18, 2024 22:51 UTC
Lichter Jay10% owner
SaleCommon Stock 61,445 $49.69 $3,053,202.05
Disclosure

SEC source: 0001415889-24-025436 · form4-10182024_101021.xml · nonDerivative · entry 3

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures SPV I, L.P.

Disclosed balance after: 2,819,366

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $49.50 to $50.45 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F4 · ownership.nature: The securities are directly held by Avalon BioVentures SPV I, LP ("ABV SPV"). ABV SPV I GP LLC ("ABV SPV GP") is the general partner of ABV SPV and may be deemed to beneficially own the securities held by ABV SPV. Mr. Lichter is a managing member of ABV SPV GP and shares voting and investment power with respect to the securities held by ABV SPV. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 16, 2024 Filed Oct 18, 2024 22:51 UTC
Lichter Jay10% owner
SaleCommon Stock 11,657 $49.69 $579,236.33
Disclosure

SEC source: 0001415889-24-025436 · form4-10182024_101021.xml · nonDerivative · entry 2

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures I, LP

Disclosed balance after: 534,883

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $49.50 to $50.45 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The securities are directly held by Avalon BioVentures I, LP ("ABV I"). Avalon BioVentures GP LLC ("ABV GP") is the general partner of ABV I and may be deemed to beneficially own the securities held by ABV I. Mr. Lichter is a managing member of ABV GP and shares voting and investment power with respect to the securities held by ABV I. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
October 16, 2024 Filed Oct 18, 2024 22:51 UTC
Lichter Jay10% owner
SaleCommon Stock 60,179 $49.69 $2,990,294.51
Disclosure

SEC source: 0001415889-24-025436 · form4-10182024_101021.xml · nonDerivative · entry 1

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,761,291

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $49.50 to $50.45 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F2 · ownership.direct: The securities are directly held by Avalon Ventures XI, L.P. ("Avalon Ventures"). Avalon Ventures XI GP, LLC ("Avalon XI GP") is the general partner of Avalon Ventures and may be deemed to beneficially own the securities held by Avalon Ventures. Mr. Lichter is a managing member of Avalon XI GP and shares voting and investment power with respect to the securities held by Avalon Ventures. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 123 $0.00 Strike: $39.80 $0.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · derivative · entry 30

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,716

Underlying: Common Stock · 123 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Immediately exercisable.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 181 $0.00 Strike: $13.22 $0.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · derivative · entry 29

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,560

Underlying: Common Stock · 181 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Immediately exercisable.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 181 $0.00 Strike: $10.73 $0.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · derivative · entry 28

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,560

Underlying: Common Stock · 181 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Immediately exercisable.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 434 $0.00 Strike: $17.00 $0.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · derivative · entry 27

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,744

Underlying: Common Stock · 434 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Immediately exercisable.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 958 $46.24 $44,297.92
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 22

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,887

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.24 to $46.31 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 123 $39.80 $4,895.40
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 21

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,845

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 181 $13.22 $2,392.82
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 20

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,722

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 181 $10.73 $1,942.13
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 19

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,541

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 30, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 434 $17.00 $7,378.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 18

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,360

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Sep 27, 2024 19:31 UTC
DiRaimondo ThomasChief Scientific Officer
SaleCommon Stock 675 $47.22 $31,876.54
Disclosure

SEC source: 0001415889-24-024076 · form4-09272024_110948.xml · nonDerivative · entry 2

DiRaimondo Thomas · CIK 0002005618 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 97,938

F1 · kind: The shares were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 28, 2024.

F4 · price: The weighted average sale price for the transaction reported was $47.2245 and the range of prices were between $46.79 and $47.77. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided.

Read SEC document
September 27, 2024 Filed Sep 27, 2024 19:31 UTC
DiRaimondo ThomasChief Scientific Officer
SaleCommon Stock 4,325 $46.21 $199,839.65
Disclosure

SEC source: 0001415889-24-024076 · form4-09272024_110948.xml · nonDerivative · entry 1

DiRaimondo Thomas · CIK 0002005618 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 98,613

F1 · kind: The shares were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 28, 2024.

F2 · price: The weighted average sale price for the transaction reported was $46.2057 and the range of prices were between $45.70 and $46.69. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided.

F3 · balance_after: Includes 1,406 shares acquired under the Issuer's 2021 Employee Stock Purchase Plan on May 15, 2024.

Read SEC document
September 27, 2024 Filed Sep 27, 2024 23:32 UTC
Meyer Andrew HollmanChief Business Officer
Exercise / conversionStock Option (right to buy) · Derivative 50,000 $0.00 Strike: $4.21 $0.00
Disclosure

SEC source: 0001415889-24-024078 · form4-09272024_110955.xml · derivative · entry 3

Meyer Andrew Hollman · CIK 0001864159 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,667

Underlying: Common Stock · 50,000 shares

Expires 2031-03-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: Immediately exercisable.

Read SEC document
September 27, 2024 Filed Sep 27, 2024 23:32 UTC
Meyer Andrew HollmanChief Business Officer
SaleCommon Stock 50,000 $45.96 $2,297,755.00
Disclosure

SEC source: 0001415889-24-024078 · form4-09272024_110955.xml · nonDerivative · entry 2

Meyer Andrew Hollman · CIK 0001864159 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 67,592

F2 · price: The weighted average sale price for the transaction reported was $45.9551 and the range of prices were between $45.55 and $46.50. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided.

Read SEC document
September 27, 2024 Filed Sep 27, 2024 23:32 UTC
Meyer Andrew HollmanChief Business Officer
Exercise / conversionCommon Stock 50,000 $4.21 $210,500.00
Disclosure

SEC source: 0001415889-24-024078 · form4-09272024_110955.xml · nonDerivative · entry 1

Meyer Andrew Hollman · CIK 0001864159 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 117,592

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 1,189 shares acquired under the Issuer's 2021 Employee Stock Purchase Plan (the "Plan") on November 15, 2021, 1,752 shares acquired under the Plan on May 13, 2022, 2,401 shares acquired under the Plan on May 15, 2023 and 2,834 shares acquired under the Plan on May 15, 2024.

Read SEC document
September 27, 2024 Filed Sep 27, 2024 23:30 UTC
Campbell David AlanDirector · President and CEO
SaleCommon Stock 795 $47.84 $38,031.53
Disclosure

SEC source: 0001415889-24-024074 · form4-09272024_110948.xml · nonDerivative · entry 3

Campbell David Alan · CIK 0001864158 · Director · President and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,054

F1 · kind: The shares were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 21, 2024.

F4 · price: The weighted average sale price for the transaction reported was $47.8384 and the range of prices were between $47.56 and $48.135. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided.

Read SEC document
September 27, 2024 Filed Sep 27, 2024 23:30 UTC
Campbell David AlanDirector · President and CEO
SaleCommon Stock 5,248 $46.86 $245,895.04
Disclosure

SEC source: 0001415889-24-024074 · form4-09272024_110948.xml · nonDerivative · entry 2

Campbell David Alan · CIK 0001864158 · Director · President and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 307,849

F1 · kind: The shares were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 21, 2024.

F3 · price: The weighted average sale price for the transaction reported was $46.855 and the range of prices were between $46.565 and $47.54. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided.

Read SEC document
September 27, 2024 Filed Sep 27, 2024 23:30 UTC
Campbell David AlanDirector · President and CEO
SaleCommon Stock 18,957 $46.09 $873,714.86
Disclosure

SEC source: 0001415889-24-024074 · form4-09272024_110948.xml · nonDerivative · entry 1

Campbell David Alan · CIK 0001864158 · Director · President and CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 313,097

F1 · kind: The shares were sold pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 21, 2024.

F2 · price: The weighted average sale price for the transaction reported was $46.0893 and the range of prices were between $45.55 and $46.54. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of shares sold at each separate price will be provided.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 234 $0.00 Strike: $39.80 $0.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · derivative · entry 26

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,839

Underlying: Common Stock · 234 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Immediately exercisable.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 345 $0.00 Strike: $13.22 $0.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · derivative · entry 25

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,741

Underlying: Common Stock · 345 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Immediately exercisable.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 345 $0.00 Strike: $10.73 $0.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · derivative · entry 24

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,741

Underlying: Common Stock · 345 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Immediately exercisable.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 828 $0.00 Strike: $17.00 $0.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · derivative · entry 23

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 28,178

Underlying: Common Stock · 828 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F11 · derivative.exercise_date: Immediately exercisable.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 1,826 $46.19 $84,342.94
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 17

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,926

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.11 to $46.22 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 234 $39.80 $9,313.20
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 16

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,752

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 345 $13.22 $4,560.90
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 15

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,518

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 345 $10.73 $3,701.85
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 14

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,173

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
Exercise / conversionCommon Stock 828 $17.00 $14,076.00
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 13

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,828

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · ownership.direct: The securities are directly held by Mr. Lichter.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 1,542 $47.74 $73,615.08
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 12

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures SPV I, L.P.

Disclosed balance after: 2,880,811

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $47.28 to $47.97 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F4 · ownership.nature: The securities are directly held by Avalon BioVentures SPV I, LP ("ABV SPV"). ABV SPV I GP LLC ("ABV SPV GP") is the general partner of ABV SPV and may be deemed to beneficially own the securities held by ABV SPV. Mr. Lichter is a managing member of ABV SPV GP and shares voting and investment power with respect to the securities held by ABV SPV. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 293 $47.74 $13,987.82
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 11

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures I, LP

Disclosed balance after: 546,540

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $47.28 to $47.97 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The securities are directly held by Avalon BioVentures I, LP ("ABV I"). Avalon BioVentures GP LLC ("ABV GP") is the general partner of ABV I and may be deemed to beneficially own the securities held by ABV I. Mr. Lichter is a managing member of ABV GP and shares voting and investment power with respect to the securities held by ABV I. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 1,511 $47.74 $72,135.14
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 10

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,821,470

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $47.28 to $47.97 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.direct: The securities are directly held by Avalon Ventures XI, L.P. ("Avalon Ventures"). Avalon Ventures XI GP, LLC ("Avalon XI GP") is the general partner of Avalon Ventures and may be deemed to beneficially own the securities held by Avalon Ventures. Mr. Lichter is a managing member of Avalon XI GP and shares voting and investment power with respect to the securities held by Avalon Ventures. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 46,861 $46.42 $2,175,287.62
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 9

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures SPV I, L.P.

Disclosed balance after: 2,882,353

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.25 to $47.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F4 · ownership.nature: The securities are directly held by Avalon BioVentures SPV I, LP ("ABV SPV"). ABV SPV I GP LLC ("ABV SPV GP") is the general partner of ABV SPV and may be deemed to beneficially own the securities held by ABV SPV. Mr. Lichter is a managing member of ABV SPV GP and shares voting and investment power with respect to the securities held by ABV SPV. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 8,894 $46.42 $412,859.48
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 8

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures I, LP

Disclosed balance after: 546,833

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.25 to $47.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The securities are directly held by Avalon BioVentures I, LP ("ABV I"). Avalon BioVentures GP LLC ("ABV GP") is the general partner of ABV I and may be deemed to beneficially own the securities held by ABV I. Mr. Lichter is a managing member of ABV GP and shares voting and investment power with respect to the securities held by ABV I. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 27, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 45,894 $46.42 $2,130,399.48
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 7

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,822,981

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.25 to $47.11 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F2 · ownership.direct: The securities are directly held by Avalon Ventures XI, L.P. ("Avalon Ventures"). Avalon Ventures XI GP, LLC ("Avalon XI GP") is the general partner of Avalon Ventures and may be deemed to beneficially own the securities held by Avalon Ventures. Mr. Lichter is a managing member of Avalon XI GP and shares voting and investment power with respect to the securities held by Avalon Ventures. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 26, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 41,661 $47.77 $1,990,145.97
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 6

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures SPV I, LP

Disclosed balance after: 2,929,214

F5 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $47.50 to $48.14 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F4 · ownership.nature: The securities are directly held by Avalon BioVentures SPV I, LP ("ABV SPV"). ABV SPV I GP LLC ("ABV SPV GP") is the general partner of ABV SPV and may be deemed to beneficially own the securities held by ABV SPV. Mr. Lichter is a managing member of ABV SPV GP and shares voting and investment power with respect to the securities held by ABV SPV. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 26, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 7,908 $47.77 $377,765.16
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 5

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures I, LP

Disclosed balance after: 555,727

F5 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $47.50 to $48.14 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The securities are directly held by Avalon BioVentures I, LP ("ABV I"). Avalon BioVentures GP LLC ("ABV GP") is the general partner of ABV I and may be deemed to beneficially own the securities held by ABV I. Mr. Lichter is a managing member of ABV GP and shares voting and investment power with respect to the securities held by ABV I. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 26, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 40,803 $47.77 $1,949,159.31
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 4

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,868,875

F5 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $47.50 to $48.14 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F2 · ownership.direct: The securities are directly held by Avalon Ventures XI, L.P. ("Avalon Ventures"). Avalon Ventures XI GP, LLC ("Avalon XI GP") is the general partner of Avalon Ventures and may be deemed to beneficially own the securities held by Avalon Ventures. Mr. Lichter is a managing member of Avalon XI GP and shares voting and investment power with respect to the securities held by Avalon Ventures. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 26, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 50,539 $46.78 $2,364,214.42
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 3

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures SPV I, L.P.

Disclosed balance after: 2,970,875

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $46.50 to $47.49 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F4 · ownership.nature: The securities are directly held by Avalon BioVentures SPV I, LP ("ABV SPV"). ABV SPV I GP LLC ("ABV SPV GP") is the general partner of ABV SPV and may be deemed to beneficially own the securities held by ABV SPV. Mr. Lichter is a managing member of ABV SPV GP and shares voting and investment power with respect to the securities held by ABV SPV. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

Read SEC document
September 26, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 9,592 $46.78 $448,713.76
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 2

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · By Avalon BioVentures I, LP

Disclosed balance after: 563,635

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $46.50 to $47.49 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F3 · ownership.nature: The securities are directly held by Avalon BioVentures I, LP ("ABV I"). Avalon BioVentures GP LLC ("ABV GP") is the general partner of ABV I and may be deemed to beneficially own the securities held by ABV I. Mr. Lichter is a managing member of ABV GP and shares voting and investment power with respect to the securities held by ABV I. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

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September 26, 2024 Filed Oct 1, 2024 00:49 UTC
Lichter Jay10% owner
SaleCommon Stock 49,497 $46.78 $2,315,469.66
Disclosure

SEC source: 0001415889-24-024119 · form4-10012024_121033.xml · nonDerivative · entry 1

Avalon Ventures XI, L.P. · CIK 0001652901 · 10% owner

Avalon BioVentures I, LP · CIK 0001873935 · 10% owner

Avalon BioVentures SPV I, L.P. · CIK 0001844550 · 10% owner

Lichter Jay · CIK 0001376355 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,909,678

F1 · price: The price reported in Column 4 is a weighted average price. These securities were sold in multiple transactions at prices ranging from $46.50 to $47.49 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of securities sold at each separate price within the range set forth in this footnote.

F2 · ownership.direct: The securities are directly held by Avalon Ventures XI, L.P. ("Avalon Ventures"). Avalon Ventures XI GP, LLC ("Avalon XI GP") is the general partner of Avalon Ventures and may be deemed to beneficially own the securities held by Avalon Ventures. Mr. Lichter is a managing member of Avalon XI GP and shares voting and investment power with respect to the securities held by Avalon Ventures. Each of the Reporting Persons disclaims beneficial ownership of these securities except to the extent of his or its respective pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purpose.

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September 13, 2024 Filed Oct 24, 2024 20:15 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 391 $0.00 Strike: $39.80 $0.00
Disclosure

SEC source: 0001415889-24-025601 · form4-10242024_041001.xml · derivative · entry 12

Lichter Jay · CIK 0001376355 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,682

Underlying: Common Stock · 391 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Immediately exercisable.

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September 13, 2024 Filed Oct 24, 2024 20:15 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 778 $0.00 Strike: $13.22 $0.00
Disclosure

SEC source: 0001415889-24-025601 · form4-10242024_041001.xml · derivative · entry 11

Lichter Jay · CIK 0001376355 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,308

Underlying: Common Stock · 778 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Immediately exercisable.

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September 13, 2024 Filed Oct 24, 2024 20:15 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 778 $0.00 Strike: $10.73 $0.00
Disclosure

SEC source: 0001415889-24-025601 · form4-10242024_041001.xml · derivative · entry 10

Lichter Jay · CIK 0001376355 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,308

Underlying: Common Stock · 778 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Immediately exercisable.

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September 13, 2024 Filed Oct 24, 2024 20:15 UTC
Lichter Jay10% owner
Exercise / conversionStock Option (right to buy) · Derivative 1,868 $0.00 Strike: $17.00 $0.00
Disclosure

SEC source: 0001415889-24-025601 · form4-10242024_041001.xml · derivative · entry 9

Lichter Jay · CIK 0001376355 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,138

Underlying: Common Stock · 1,868 shares

Expires 2027-07-19

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: Immediately exercisable.

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September 13, 2024 Filed Oct 24, 2024 20:15 UTC
Lichter Jay10% owner
SaleCommon Stock 3,815 $46.68 $178,084.20
Disclosure

SEC source: 0001415889-24-025601 · form4-10242024_041001.xml · nonDerivative · entry 5

Lichter Jay · CIK 0001376355 · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,000

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Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.