Last 12 months
Inside the activity.
0 purchase rows · 74 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 11 |
| Dec 2025 | 0 | 7 |
| Jan 2026 | 0 | 6 |
| Feb 2026 | 0 | 6 |
| Mar 2026 | 0 | 9 |
| Apr 2026 | 0 | 2 |
| May 2026 | 0 | 6 |
| Jun 2026 | 0 | 7 |
| Jul 2026 | 0 | 5 |
| Aug 2026 | 0 | 9 |
| Sep 2026 | 0 | 6 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| April 27, 2023 Filed Apr 28, 2023 23:04 UTC |
LEVY ALAN JDirector
|
GrantNon-Qualified Stock Option (right to buy) · Derivative | 1,709 | $0.00 Strike: $295.92 | $0.00 |
DisclosureSEC source: 0001035267-23-000120 · edgardoc.xml · derivative · entry 2 LEVY ALAN J · CIK 0001280627 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,709 Underlying: Common Stock · 1,709 shares Expires 2030-04-26 F1 · derivative.exercise_date: 100% of the shares subject to the option shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service as a director to the issuer. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:04 UTC |
LEVY ALAN JDirector
|
Exercise / conversionCommon Stock | 482 | $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000120 · edgardoc.xml · nonDerivative · entry 1 LEVY ALAN J · CIK 0001280627 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 25,319 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:09 UTC |
Ladd Amy LDirector
|
GrantRestricted Stock Units · Derivative | 569 | $0.00 Strike: $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000122 · edgardoc.xml · derivative · entry 4 Ladd Amy L · CIK 0001781750 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 569 Underlying: Common Stock · 569 shares Expires not disclosed F2 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. F2 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:09 UTC |
Ladd Amy LDirector
|
Exercise / conversionRestricted Stock Units · Derivative | 482 | $0.00 Strike: $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000122 · edgardoc.xml · derivative · entry 3 Ladd Amy L · CIK 0001781750 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 482 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. F2 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:09 UTC |
Ladd Amy LDirector
|
GrantNon-Qualified Stock Option (right to buy) · Derivative | 1,709 | $0.00 Strike: $295.92 | $0.00 |
DisclosureSEC source: 0001035267-23-000122 · edgardoc.xml · derivative · entry 2 Ladd Amy L · CIK 0001781750 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,709 Underlying: Common Stock · 1,709 shares Expires 2030-04-26 F1 · derivative.exercise_date: 100% of the shares subject to the option shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service as a director to the issuer. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:09 UTC |
Ladd Amy LDirector
|
Exercise / conversionCommon Stock | 482 | $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000122 · edgardoc.xml · nonDerivative · entry 1 Ladd Amy L · CIK 0001781750 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,202 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:13 UTC |
NACHTSHEIM JAMI KDirector
|
GrantRestricted Stock Units · Derivative | 569 | $0.00 Strike: $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000124 · edgardoc.xml · derivative · entry 4 NACHTSHEIM JAMI K · CIK 0001223017 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 569 Underlying: Common Stock · 569 shares Expires not disclosed F2 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. F2 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:13 UTC |
NACHTSHEIM JAMI KDirector
|
Exercise / conversionRestricted Stock Units · Derivative | 482 | $0.00 Strike: $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000124 · edgardoc.xml · derivative · entry 3 NACHTSHEIM JAMI K · CIK 0001223017 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 482 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. F2 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:13 UTC |
NACHTSHEIM JAMI KDirector
|
GrantNon-Qualified Stock Option (right to buy) · Derivative | 1,709 | $0.00 Strike: $295.92 | $0.00 |
DisclosureSEC source: 0001035267-23-000124 · edgardoc.xml · derivative · entry 2 NACHTSHEIM JAMI K · CIK 0001223017 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,709 Underlying: Common Stock · 1,709 shares Expires 2030-04-26 F1 · derivative.exercise_date: 100% of the shares subject to the option shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service as a director to the issuer. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:13 UTC |
NACHTSHEIM JAMI KDirector
|
Exercise / conversionCommon Stock | 482 | $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000124 · edgardoc.xml · nonDerivative · entry 1 NACHTSHEIM JAMI K · CIK 0001223017 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 5,063 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:20 UTC |
Reed Monica PDirector
|
GrantRestricted Stock Units · Derivative | 569 | $0.00 Strike: $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000126 · edgardoc.xml · derivative · entry 4 Reed Monica P · CIK 0001854171 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 569 Underlying: Common Stock · 569 shares Expires not disclosed F2 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. F2 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:20 UTC |
Reed Monica PDirector
|
Exercise / conversionRestricted Stock Units · Derivative | 482 | $0.00 Strike: $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000126 · edgardoc.xml · derivative · entry 3 Reed Monica P · CIK 0001854171 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 482 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. F2 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:20 UTC |
Reed Monica PDirector
|
GrantNon-Qualified Stock Option (right to buy) · Derivative | 1,709 | $0.00 Strike: $295.92 | $0.00 |
DisclosureSEC source: 0001035267-23-000126 · edgardoc.xml · derivative · entry 2 Reed Monica P · CIK 0001854171 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,709 Underlying: Common Stock · 1,709 shares Expires 2030-04-26 F1 · derivative.exercise_date: 100% of the shares subject to the option shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service as a director to the issuer. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:20 UTC |
Reed Monica PDirector
|
Exercise / conversionCommon Stock | 482 | $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000126 · edgardoc.xml · nonDerivative · entry 1 Reed Monica P · CIK 0001854171 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,037 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:31 UTC |
RUBASH MARK JDirector
|
GrantRestricted Stock Units · Derivative | 569 | $0.00 Strike: $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000128 · edgardoc.xml · derivative · entry 4 RUBASH MARK J · CIK 0001209186 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 569 Underlying: Common Stock · 569 shares Expires not disclosed F2 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. F2 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:31 UTC |
RUBASH MARK JDirector
|
Exercise / conversionRestricted Stock Units · Derivative | 482 | $0.00 Strike: $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000128 · edgardoc.xml · derivative · entry 3 RUBASH MARK J · CIK 0001209186 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 482 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · derivative.exercise_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. F2 · derivative.expiration_date: 100% of the RSUs shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:31 UTC |
RUBASH MARK JDirector
|
GrantNon-Qualified Stock Option (right to buy) · Derivative | 1,709 | $0.00 Strike: $295.92 | $0.00 |
DisclosureSEC source: 0001035267-23-000128 · edgardoc.xml · derivative · entry 2 RUBASH MARK J · CIK 0001209186 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,709 Underlying: Common Stock · 1,709 shares Expires 2030-04-26 F1 · derivative.exercise_date: 100% of the shares subject to the option shall vest on the earlier of the one year anniversary of the date of grant or the next Annual Meeting of Stockholders, subject to the Reporting Person's continued service as a director to the issuer. Read SEC document |
| April 27, 2023 Filed Apr 28, 2023 23:31 UTC |
RUBASH MARK JDirector
|
Exercise / conversionCommon Stock | 482 | $0.00 | $0.00 |
DisclosureSEC source: 0001035267-23-000128 · edgardoc.xml · nonDerivative · entry 1 RUBASH MARK J · CIK 0001209186 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 15,482 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 24, 2023 Filed Apr 25, 2023 01:37 UTC |
Rosa David J.EVP Chief Strategy & Growth Of
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 54,000 | $0.00 Strike: $42.64 | $0.00 |
DisclosureSEC source: 0001035267-23-000107 · edgardoc.xml · derivative · entry 6 Rosa David J. · CIK 0001519593 · EVP Chief Strategy & Growth Of 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 54,000 shares Expires 2023-08-15 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 15, 2023. F4 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. Option shall vest 7/48 one month after the date of grant and 1/48 each month thereafter. Read SEC document |
| April 24, 2023 Filed Apr 25, 2023 01:37 UTC |
Rosa David J.EVP Chief Strategy & Growth Of
|
SaleCommon Stock | 40,764 | $299.20 | $12,196,446.13 |
DisclosureSEC source: 0001035267-23-000107 · edgardoc.xml · nonDerivative · entry 4 Rosa David J. · CIK 0001519593 · EVP Chief Strategy & Growth Of 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 155,712 F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 15, 2023. F3 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $297.79 to $301.83 as follows: 10,560 shares sold at $297.79 to $298.78; 28,240 shares sold at $298.84 to $299.84; 1,364 shares sold at $299.99 to $300.50; and 600 shares sold at $301.83. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 24, 2023 Filed Apr 25, 2023 01:37 UTC |
Rosa David J.EVP Chief Strategy & Growth Of
|
Exercise / conversionCommon Stock | 54,000 | $42.64 | $2,302,381.80 |
DisclosureSEC source: 0001035267-23-000107 · edgardoc.xml · nonDerivative · entry 3 Rosa David J. · CIK 0001519593 · EVP Chief Strategy & Growth Of 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 196,476 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 15, 2023. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:08 UTC |
Curet MyriamEVP & Chief Medical Officer
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 6,000 | $0.00 Strike: $174.26 | $0.00 |
DisclosureSEC source: 0001035267-23-000094 · edgardoc.xml · derivative · entry 8 Curet Myriam · CIK 0001632901 · EVP & Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 6,000 shares Expires 2028-08-15 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 10, 2023. F3 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. Option shall vest 7/48 one month after the date of grant and 1/48 each month thereafter. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:08 UTC |
Curet MyriamEVP & Chief Medical Officer
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,000 | $0.00 Strike: $166.62 | $0.00 |
DisclosureSEC source: 0001035267-23-000094 · edgardoc.xml · derivative · entry 7 Curet Myriam · CIK 0001632901 · EVP & Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 4,500 Underlying: Common Stock · 2,000 shares Expires 2029-08-15 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 10, 2023. F3 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. Option shall vest 7/48 one month after the date of grant and 1/48 each month thereafter. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:08 UTC |
Curet MyriamEVP & Chief Medical Officer
|
SaleCommon Stock | 505 | $300.00 | $151,500.00 |
DisclosureSEC source: 0001035267-23-000094 · edgardoc.xml · nonDerivative · entry 6 Curet Myriam · CIK 0001632901 · EVP & Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 327 F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 10, 2023. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:08 UTC |
Curet MyriamEVP & Chief Medical Officer
|
SaleCommon Stock | 1,118 | $297.92 | $333,070.65 |
DisclosureSEC source: 0001035267-23-000094 · edgardoc.xml · nonDerivative · entry 5 Curet Myriam · CIK 0001632901 · EVP & Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 832 F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 10, 2023. F2 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.54 to $299.27 as follows: 232 shares sold at $296.54 - $297.32; 666 shares sold at $297.57 - $298.50; 220 shares sold at $298.62 - $299.27. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:08 UTC |
Curet MyriamEVP & Chief Medical Officer
|
SaleCommon Stock | 6,000 | $300.00 | $1,800,006.60 |
DisclosureSEC source: 0001035267-23-000094 · edgardoc.xml · nonDerivative · entry 4 Curet Myriam · CIK 0001632901 · EVP & Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,950 F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 10, 2023. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:08 UTC |
Curet MyriamEVP & Chief Medical Officer
|
Exercise / conversionCommon Stock | 6,000 | $174.26 | $1,045,540.20 |
DisclosureSEC source: 0001035267-23-000094 · edgardoc.xml · nonDerivative · entry 3 Curet Myriam · CIK 0001632901 · EVP & Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 7,950 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 10, 2023. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:08 UTC |
Curet MyriamEVP & Chief Medical Officer
|
SaleCommon Stock | 2,000 | $300.00 | $600,002.20 |
DisclosureSEC source: 0001035267-23-000094 · edgardoc.xml · nonDerivative · entry 2 Curet Myriam · CIK 0001632901 · EVP & Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,950 F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 10, 2023. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:08 UTC |
Curet MyriamEVP & Chief Medical Officer
|
Exercise / conversionCommon Stock | 2,000 | $166.62 | $333,246.60 |
DisclosureSEC source: 0001035267-23-000094 · edgardoc.xml · nonDerivative · entry 1 Curet Myriam · CIK 0001632901 · EVP & Chief Medical Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 3,950 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: The transaction took place in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on August 10, 2023. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,000 | $0.00 Strike: $41.26 | $0.00 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · derivative · entry 10 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 3,567 Underlying: Common Stock · 2,000 shares Expires 2024-04-24 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. F5 · derivative.exercise_date: Non-statutory stock option granted pursuant to the Non-Employee Directors' Stock Option Plan. Option shall vest 100% one year after the date of grant or at the next Shareholders Meeting, whichever should take place first, provided that vesting will cease on termination of the Directors service to the Company. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,000 | $0.00 Strike: $41.26 | $0.00 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · derivative · entry 9 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 5,567 Underlying: Common Stock · 2,000 shares Expires 2024-04-24 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. F5 · derivative.exercise_date: Non-statutory stock option granted pursuant to the Non-Employee Directors' Stock Option Plan. Option shall vest 100% one year after the date of grant or at the next Shareholders Meeting, whichever should take place first, provided that vesting will cease on termination of the Directors service to the Company. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,000 | $0.00 Strike: $41.26 | $0.00 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · derivative · entry 8 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 7,567 Underlying: Common Stock · 2,000 shares Expires 2024-04-24 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. F5 · derivative.exercise_date: Non-statutory stock option granted pursuant to the Non-Employee Directors' Stock Option Plan. Option shall vest 100% one year after the date of grant or at the next Shareholders Meeting, whichever should take place first, provided that vesting will cease on termination of the Directors service to the Company. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
SaleCommon Stock | 2,000 | $297.92 | $595,836.60 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · nonDerivative · entry 6 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. F4 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.42 to $299.23 as follows: 366 shares sold at $296.42 - 297.14; 1,254 shares sold at $297.52 - $298.46; 380 shares sold at $298.63 - $299.23. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
Exercise / conversionCommon Stock | 2,000 | $41.26 | $82,515.60 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · nonDerivative · entry 5 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 2,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
SaleCommon Stock | 2,000 | $297.93 | $595,850.40 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · nonDerivative · entry 4 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. F3 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.56 to $299.20 as follows: 404 shares sold at $296.56 - 297.56; 1,201 shares sold at $297.6 - $298.59; and 395 shares sold at $298.61 - $299.20. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
Exercise / conversionCommon Stock | 2,000 | $41.26 | $82,515.60 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · nonDerivative · entry 3 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 2,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
SaleCommon Stock | 2,000 | $297.92 | $595,837.20 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · nonDerivative · entry 2 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 0 F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. F2 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.42 to $299.21 as follows: 384 shares at $296.42 - $297.12; 1,216 shares at $297.57 -$298.50; 400 shares at $298.58 - $299.21. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 21:53 UTC |
BARRATT CRAIG HDirector
|
Exercise / conversionCommon Stock | 2,000 | $41.26 | $82,515.60 |
DisclosureSEC source: 0001035267-23-000097 · edgardoc.xml · nonDerivative · entry 1 BARRATT CRAIG H · CIK 0001277620 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 2,000 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on March 1, 2024. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,184 | $0.00 Strike: $245.60 | $0.00 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · derivative · entry 17 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 4,566 Underlying: Common Stock · 2,184 shares Expires 2031-02-26 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F7 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. The option vests 1/8th six months after the date of grant and 1/48th monthly thereafter. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 1,086 | $0.00 Strike: $242.34 | $0.00 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · derivative · entry 16 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 996 Underlying: Common Stock · 1,086 shares Expires 2030-08-28 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F9 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. Option shall vest 7/48 one month after the date of grant and 1/48 each month thereafter. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 2,444 | $0.00 Strike: $208.90 | $0.00 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · derivative · entry 15 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 6,579 Underlying: Common Stock · 2,444 shares Expires 2029-08-28 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F9 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. Option shall vest 7/48 one month after the date of grant and 1/48 each month thereafter. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 273 | $0.00 Strike: $179.70 | $0.00 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · derivative · entry 14 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,176 Underlying: Common Stock · 273 shares Expires 2030-05-11 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F8 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. The grant vests 25% on the first anniversary of the date of grant and monthly thereafter, over a four year period of time. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
Exercise / conversionNon-Qualified Stock Option (right to buy) · Derivative | 273 | $0.00 Strike: $177.99 | $0.00 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · derivative · entry 13 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 996 Underlying: Common Stock · 273 shares Expires 2030-02-28 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F7 · derivative.exercise_date: Non-statutory stock option granted pursuant to the 2010 Incentive Award Plan. The option vests 1/8th six months after the date of grant and 1/48th monthly thereafter. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
SaleCommon Stock | 1,167 | $297.90 | $347,644.98 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · nonDerivative · entry 12 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 7,065 F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F6 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.39 to $299.22 as follows: 216 shares sold at $296.39 to $297.12; 705 shares sold at $297.42 to $298.41; and 246 shares sold at $298.50 to $299.22. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
SaleCommon Stock | 1,196 | $297.91 | $356,302.27 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · nonDerivative · entry 11 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 8,232 F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F5 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.59 to $299.27 as follows: 271 shares sold at $296.59 to $297.41; 725 shares sold at $297.66 to $298.62; and 200 shares sold at $298.68 to $299.27. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
SaleCommon Stock | 2,444 | $297.93 | $728,133.83 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · nonDerivative · entry 10 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 9,428 F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F4 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.52 to $299.30 as follows: 612 shares sold at $296.52 to $297.52; 1.413 shares sold at $297.57 to $298.50; and 419 shares sold at $298.63 to $299.30. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
Exercise / conversionCommon Stock | 2,444 | $208.90 | $510,551.60 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · nonDerivative · entry 9 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 11,872 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
SaleCommon Stock | 273 | $298.00 | $81,353.67 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · nonDerivative · entry 8 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 9,428 F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F3 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.61 to $299.31 as follows: 116 shares sold at $296.61 to $297.00; 370 shares sold at $297.78 to $298.74; and 60 shares sold at $298.99 to $299.31. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
Exercise / conversionCommon Stock | 273 | $177.99 | $48,590.37 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · nonDerivative · entry 7 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 9,701 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. Read SEC document |
| April 21, 2023 Filed Apr 24, 2023 22:10 UTC |
DeSantis RobertEVP & Chief Product Officer
|
SaleCommon Stock | 273 | $298.00 | $81,353.67 |
DisclosureSEC source: 0001035267-23-000099 · edgardoc.xml · nonDerivative · entry 6 DeSantis Robert · CIK 0001808942 · EVP & Chief Product Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 9,428 F1 · kind: These shares were sold in accordance with a Trading Plan that complies with SEC Rule 10b5-1 and expires on November 21, 2023. F3 · price: The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $296.61 to $299.31 as follows: 116 shares sold at $296.61 to $297.00; 370 shares sold at $297.78 to $298.74; and 60 shares sold at $298.99 to $299.31. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.