IRLA

SEC source: 0001209191-20-063615 · doc4.xml · derivative · entry 9

Holsinger Leslie · CIK 0001770821 · Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-12-10

F3 · derivative.exercise_date: 50% of the shares will vest on March 31, 2023 provided that the Issuer's Compensation Committee has determined that Performance Condition No. 1 (as defined below) has been met, and 50% of the shares will vest on March 31, 2024 provided that the Issuer's Compensation Committee has determined that Performance Condition No. 2 (as defined below) has been met; provided further that, in each case, the grantee will have been continuously a service provider from the date of grant through each such vesting date. Performance Condition No. 1 means that the average closing price per share of the Issuer's common stock in any 45 consecutive trading day period prior to March 15, 2023 has exceeded $135 per share. Performance Condition No. 2 means that the average closing price per share of the Issuer's common stock in any 45 consecutive trading day period prior to March 15, 2024 has exceeded $170 per share.

SEC source: 0001209191-20-063615 · doc4.xml · derivative · entry 8

Holsinger Leslie · CIK 0001770821 · Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-12-10

F2 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments from the vesting commencement date, subject to the grantee's continuous service to the Issuer on each such date.

SEC source: 0001209191-20-063604 · doc4.xml · derivative · entry 2

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-12-10

F2 · derivative.exercise_date: 50% of the shares will vest on March 31, 2023 provided that the Issuer's Compensation Committee has determined that Performance Condition No. 1 (as defined below) has been met, and 50% of the shares will vest on March 31, 2024 provided that the Issuer's Compensation Committee has determined that Performance Condition No. 2 (as defined below) has been met; provided further that, in each case, the grantee will have been continuously a service provider from the date of grant through each such vesting date. Performance Condition No. 1 means that the average closing price per share of the Issuer's common stock in any 45 consecutive trading day period prior to March 15, 2023 has exceeded $135 per share. Performance Condition No. 2 means that the average closing price per share of the Issuer's common stock in any 45 consecutive trading day period prior to March 15, 2024 has exceeded $170 per share.

SEC source: 0001209191-20-063604 · doc4.xml · derivative · entry 1

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-12-10

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments from the vesting commencement date, subject to the grantee's continuous service to the Issuer on each such date.

SEC source: 0001209191-20-063602 · doc4.xml · derivative · entry 2

Dominy Stephen S. · CIK 0001770860 · Director · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-12-10

F2 · derivative.exercise_date: 50% of the shares will vest on March 31, 2023 provided that the Issuer's Compensation Committee has determined that Performance Condition No. 1 (as defined below) has been met, and 50% of the shares will vest on March 31, 2024 provided that the Issuer's Compensation Committee has determined that Performance Condition No. 2 (as defined below) has been met; provided further that, in each case, the grantee will have been continuously a service provider from the date of grant through each such vesting date. Performance Condition No. 1 means that the average closing price per share of the Issuer's common stock in any 45 consecutive trading day period prior to March 15, 2023 has exceeded $135 per share. Performance Condition No. 2 means that the average closing price per share of the Issuer's common stock in any 45 consecutive trading day period prior to March 15, 2024 has exceeded $170 per share.

SEC source: 0001209191-20-063602 · doc4.xml · derivative · entry 1

Dominy Stephen S. · CIK 0001770860 · Director · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-12-10

F1 · derivative.exercise_date: The shares subject to the option vest in 48 equal monthly installments from the vesting commencement date, subject to the grantee's continuous service to the Issuer on each such date.

SEC source: 0001209191-20-063277 · doc4.xml · derivative · entry 2

Holsinger Leslie · CIK 0001770821 · Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,794

Underlying: Common Stock · 3,500 shares

Expires 2026-05-09

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The option vested at the rate of 25% of the shares on April 4, 2017, and the remaining 75% of shares vested in equal monthly installments beginning on May 4, 2017 until all the shares were fully vested on April 4, 2020.

SEC source: 0001209191-20-063277 · doc4.xml · nonDerivative · entry 1

Holsinger Leslie · CIK 0001770821 · Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001779453-20-000005 · primary_doc.xml · nonDerivative · entry 2

EPIQ Capital Group, LLC · CIK 0001779453 · IA/Managing Member of 10% Owne

Boeding Chad · CIK 0001779451 · Managing Member of Managing Me

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Mr. Boeding as Trustee of the Boeding Family Trust

Disclosed balance after: 2,860,967

F1 · ownership.direct: The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own more than 10% of the common stock of the issuer. Mr. Boeding is the Manager of EPIQ. EPIQ is filing this Form 4 on behalf of itself and Mr. Boeding jointly, but not as a group. CTYM, CTEPQ and Mr. Boeding disclaims beneficial ownership of the shares reported herein for purposes of Section 16 of the Securities Exchange Act of 1934 except to the extent of its or his pecuniary interest therein, if any. This report shall not be deemed an admission that any of the Reporting Persons is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

SEC source: 0001779453-20-000005 · primary_doc.xml · nonDerivative · entry 1

EPIQ Capital Group, LLC · CIK 0001779453 · IA/Managing Member of 10% Owne

Boeding Chad · CIK 0001779451 · Managing Member of Managing Me

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Mr. Boeding as Trustee of the Boeding Family Trust

Disclosed balance after: 2,858,527

F1 · ownership.direct: The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own more than 10% of the common stock of the issuer. Mr. Boeding is the Manager of EPIQ. EPIQ is filing this Form 4 on behalf of itself and Mr. Boeding jointly, but not as a group. CTYM, CTEPQ and Mr. Boeding disclaims beneficial ownership of the shares reported herein for purposes of Section 16 of the Securities Exchange Act of 1934 except to the extent of its or his pecuniary interest therein, if any. This report shall not be deemed an admission that any of the Reporting Persons is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

SEC source: 0001209191-20-035425 · doc4.xml · derivative · entry 1

YOUNG KEVIN · CIK 0001303643 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,029

Underlying: Common Stock · 11,029 shares

Expires 2030-06-07

F1 · derivative.exercise_date: This option shall fully vest on the one-year anniversary of the grant date, subject to the reporting person's continued services as a member of the board of directors of Cortexyme, Inc. through such vesting date.

SEC source: 0001209191-20-035423 · doc4.xml · derivative · entry 1

RYAN UNA S · CIK 0001255349 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,029

Underlying: Common Stock · 11,029 shares

Expires 2030-06-07

F1 · derivative.exercise_date: This option shall fully vest on the one-year anniversary of the grant date, subject to the reporting person's continued services as a member of the board of directors of Cortexyme, Inc. through such vesting date.

SEC source: 0001209191-20-035424 · doc4.xml · derivative · entry 1

Senner Christopher J. · CIK 0001648367 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,029

Underlying: Common Stock · 11,029 shares

Expires 2030-06-07

F1 · derivative.exercise_date: This option shall fully vest on the one-year anniversary of the grant date, subject to the reporting person's continued services as a member of the board of directors of Cortexyme, Inc. through such vesting date.

SEC source: 0001209191-20-035421 · doc4.xml · derivative · entry 1

McLoughlin Margaret · CIK 0001770823 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,029

Underlying: Common Stock · 11,029 shares

Expires 2030-06-07

F1 · derivative.exercise_date: This option shall fully vest on the one-year anniversary of the grant date, subject to the reporting person's continued services as a member of the board of directors of Cortexyme, Inc. through such vesting date.

SEC source: 0001209191-20-035419 · doc4.xml · derivative · entry 1

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,029

Underlying: Common Stock · 11,029 shares

Expires 2030-06-07

F1 · derivative.exercise_date: This option shall fully vest on the one-year anniversary of the grant date, subject to the reporting person's continued services as a member of the board of directors of Cortexyme, Inc. through such vesting date.

SEC source: 0001209191-20-035104 · doc4.xml · nonDerivative · entry 3

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,747,109

F4 · price: The range of prices for the shares of Common Stock is from $43.61 to $44.10. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-035104 · doc4.xml · nonDerivative · entry 2

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,722,235

F3 · price: The range of prices for the shares of Common Stock is from $42.61 to $43.60. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-035104 · doc4.xml · nonDerivative · entry 1

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,711,593

F1 · price: The range of prices for the shares of Common Stock is from $41.58 to $42.55. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0000078003-20-000038 · primary_doc.xml · nonDerivative · entry 1

PFIZER INC · CIK 0000078003 · 10% owner

Pfizer Strategic Investment Holdings LLC · CIK 0001776115 · 10% owner

Pfizer Ventures (US) LLC · CIK 0001776087 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,879,973

F1 · shares: All of the shares disposed of were sold by Pfizer Inc. ("Pfizer")

F2 · balance_after: Represents 2,410,071 shares held of record by Pfizer Ventures (US) LLC, a controlled affiliate of Pfizer, 254,205 shares held of record by Pfizer, and 215,697 shares held of record by Pfizer Strategic Investment Holdings LLC, a controlled affiliate of Pfizer.

F3 · ownership.direct: Each Reporting Person disclaims beneficial ownership of securities reported on this Form 4, except to the extent of its respective pecuniary interest therein.

SEC source: 0001209191-20-032970 · doc4.xml · derivative · entry 2

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,091

Underlying: Common Stock · 5,515 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The option vested as to 25% of the shares on December 16, 2019, with the remaining 75% of shares vesting in equal monthly installments beginning on January 16, 2020 and ending on December 16, 2022.

SEC source: 0001209191-20-032970 · doc4.xml · nonDerivative · entry 1

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,261

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001779453-20-000002 · primary_doc.xml · nonDerivative · entry 4

EPIQ Capital Group, LLC · CIK 0001779453 · IA/Managing Member of 10% Owne

Boeding Chad · CIK 0001779451 · Managing Member of 10% Owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Mr. Boeding as Trustee for the Boeding Family Trust

Disclosed balance after: 2,851,927

F1 · ownership.direct: The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own +10% of the common stock of the issuer. Mr. Boeding is the Managing Member of EPIQ. EPIQ is filing this Form 4 on behalf of itself and Mr. Boeding jointly, but not as a group, and each reporting person expressly disclaims membership in a group, within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended.

SEC source: 0001779453-20-000002 · primary_doc.xml · nonDerivative · entry 3

EPIQ Capital Group, LLC · CIK 0001779453 · IA/Managing Member of 10% Owne

Boeding Chad · CIK 0001779451 · Managing Member of 10% Owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Mr. Boeding as Trustee for the Boeding Family Trust

Disclosed balance after: 2,849,842

F1 · ownership.direct: The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own +10% of the common stock of the issuer. Mr. Boeding is the Managing Member of EPIQ. EPIQ is filing this Form 4 on behalf of itself and Mr. Boeding jointly, but not as a group, and each reporting person expressly disclaims membership in a group, within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended.

SEC source: 0001779453-20-000002 · primary_doc.xml · nonDerivative · entry 2

EPIQ Capital Group, LLC · CIK 0001779453 · IA/Managing Member of 10% Owne

Boeding Chad · CIK 0001779451 · Managing Member of 10% Owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Mr. Boeding as Trustee for the Boeding Family Trust

Disclosed balance after: 2,849,322

F1 · ownership.direct: The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own +10% of the common stock of the issuer. Mr. Boeding is the Managing Member of EPIQ. EPIQ is filing this Form 4 on behalf of itself and Mr. Boeding jointly, but not as a group, and each reporting person expressly disclaims membership in a group, within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended.

SEC source: 0001779453-20-000002 · primary_doc.xml · nonDerivative · entry 1

EPIQ Capital Group, LLC · CIK 0001779453 · IA/Managing Member of 10% Owne

Boeding Chad · CIK 0001779451 · Managing Member of 10% Owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Mr. Boeding as Trustee for the Boeding Family Trust

Disclosed balance after: 2,848,905

F1 · ownership.direct: The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own +10% of the common stock of the issuer. Mr. Boeding is the Managing Member of EPIQ. EPIQ is filing this Form 4 on behalf of itself and Mr. Boeding jointly, but not as a group, and each reporting person expressly disclaims membership in a group, within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 9

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,697,984

F9 · price: The range of prices for the shares of Common Stock is from $55.90 to $56.87. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 8

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,665,090

F8 · price: The range of prices for the shares of Common Stock is from $54.895 to $55.77. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 7

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,659,184

F7 · price: The range of prices for the shares of Common Stock is from $53.65 to $54.53. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 6

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,658,784

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 5

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,658,684

F6 · price: The range of prices for the shares of Common Stock is from $51.95 to $52.57. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 4

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,658,184

F5 · price: The range of prices for the shares of Common Stock is from $50.38 to $51.36. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 3

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,657,184

F4 · price: The range of prices for the shares of Common Stock is from $48.70 to $49.625. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 2

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,655,584

F3 · price: The range of prices for the shares of Common Stock is from $47.68 to $48.64. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-030688 · doc4.xml · nonDerivative · entry 1

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,654,599

F1 · price: The range of prices for the shares of Common Stock is from $45.80 to $46.75. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price.

F2 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-029819 · doc4.xml · derivative · entry 1

McDowell Caryn Gordon · CIK 0001674232 · Chief Legal & Adm. Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 200,000

Underlying: Common Stock · 200,000 shares

Expires 2030-05-13

F1 · derivative.exercise_date: Twenty-five percent (25%) of the shares subject to the stock option shall vest on May 5, 2021 with the remaining vesting monthly over the next 36 months.

SEC source: 0001209191-20-030020 · doc4.xml · derivative · entry 1

LOWE CHRISTOPHER P. · CIK 0001376260 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2030-05-13

F1 · derivative.exercise_date: 1/48th of the total number of shares subject to this option will vest and become exercisable on each monthly anniversary of the vesting start date, beginning March 29, 2020.

SEC source: 0001209191-20-030022 · doc4.xml · derivative · entry 1

Holsinger Leslie · CIK 0001770821 · Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 30,000

Underlying: Common Stock · 30,000 shares

Expires 2030-05-13

F1 · derivative.exercise_date: 1/48th of the total number of shares subject to this option will vest and become exercisable on each monthly anniversary of the vesting start date, beginning March 29, 2020.

SEC source: 0001209191-20-023626 · doc4.xml · derivative · entry 2

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 109,606

Underlying: Common Stock · 5,515 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The option will vest as to 25% of the shares on December 16, 2019, with the remaining 75% of shares vesting in equal monthly installments beginning on January 16, 2020 and ending on December 16, 2022.

SEC source: 0001209191-20-023626 · doc4.xml · nonDerivative · entry 1

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,746

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-20-008073 · doc4.xml · nonDerivative · entry 1

Lamond David · CIK 0001770790 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By Blue Devil Trust dated 12/03/2010

Disclosed balance after: 1,653,336

F1 · ownership.nature: Mr. Lamond is the trustee of Blue Devil Trust dated 12/03/2010 (the "Trust") and holds sole voting and dispositive power with respect to the shares held of record by the Trust.

SEC source: 0001209191-20-008070 · doc4.xml · derivative · entry 3

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 115,121

Underlying: Common Stock · 17,231 shares

Expires 2029-02-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The option will vest as to 25% of the shares on December 16, 2019, with the remaining 75% of shares vesting in equal monthly installments beginning on January 16, 2020 and ending on December 16, 2022.

SEC source: 0001209191-20-008070 · doc4.xml · nonDerivative · entry 1

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,231

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-20-008065 · doc4.xml · derivative · entry 1

LOWE CHRISTOPHER P. · CIK 0001376260 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-02-05

F1 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest and become exercisable monthly over four years.

SEC source: 0001209191-20-008069 · doc4.xml · derivative · entry 1

Gafric Kristen · CIK 0001770840 · SVP, Legal & Administration

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-02-05

F1 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest and become exercisable monthly over four years.

SEC source: 0001209191-20-008070 · doc4.xml · derivative · entry 2

Detke Michael J. · CIK 0001770786 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-02-05

F1 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest and become exercisable monthly over four years.

SEC source: 0001209191-20-008068 · doc4.xml · derivative · entry 1

Dominy Stephen S. · CIK 0001770860 · Director · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-02-05

F1 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest and become exercisable monthly over four years.

SEC source: 0001209191-20-008066 · doc4.xml · derivative · entry 1

Holsinger Leslie · CIK 0001770821 · Executive Vice President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2030-02-05

F1 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest and become exercisable monthly over four years.

SEC source: 0001209191-20-008064 · doc4.xml · derivative · entry 1

Lynch Casey · CIK 0001770783 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 175,000

Underlying: Common Stock · 175,000 shares

Expires 2030-02-05

F1 · derivative.exercise_date: 1/48th of the shares subject to the option shall vest and become exercisable monthly over four years.

SEC source: 0001779453-20-000001 · primary_doc.xml · nonDerivative · entry 1

EPIQ Capital Group, LLC · CIK 0001779453 · IA/Managing Member of 10% Owne

Boeding Chad · CIK 0001779451 · Managing Member of Managing Me

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · By Mr. Boeding as Trustee for the Mitsou Peterson-Cushing 2019 Irrevocable Trust

Disclosed balance after: 2,843,237

F1 · kind: Shares were distributed in kind to the beneficiary of the Trust.

F3 · price: Shares distributed in kind. Reported price is the average of the high and low price for the day.

F2 · ownership.direct: The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own +10% of the common stock of the issuer. Mr. Boeding is the Managing Member of EPIQ. EPIQ is filing this Form 4 on behalf of itself and Mr. Boeding jointly, but not as a group, and each reporting person expressly disclaims membership in a group, within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended.

SEC source: 0001779453-19-000003 · primary_doc.xml · nonDerivative · entry 4

EPIQ Capital Group, LLC · CIK 0001779453 · IA/Managing Member 10% owner

Boeding Chad · CIK 0001779451 · Managing Member of IA

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 2,834,561

F1 · ownership.direct: The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own +10% of the common stock of the issuer. Mr. Boeding is the Managing Member of EPIQ. EPIQ is filing this Form 4 on behalf of itself and Mr. Boeding jointly, but not as a group, and each reporting person expressly disclaims membership in a group, within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended.

F2 · ownership.direct: Beneficially owned directly by Mr. Boeding.