ILMN

SEC source: 0001127602-25-008707 · form4.xml · derivative · entry 3

Dhingra Ankur · CIK 0001849682 · SVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,437

Underlying: Common Stock · 11,437 shares

Expires 2028-01-02

F4 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F4 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008707 · form4.xml · derivative · entry 2

Dhingra Ankur · CIK 0001849682 · SVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,437

Underlying: Common Stock · 11,437 shares

Expires 2028-01-02

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001127602-25-008707 · form4.xml · nonDerivative · entry 1

Dhingra Ankur · CIK 0001849682 · SVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,806

F1 · shares: Grant of restricted stock units shall vest as follows: 25% of the shares subject to the award shall vest on each of February 15, 2026, February 15, 2027, February 15, 2028, and February 15, 2029, subject to awardee's continuing status as a service provider on such dates.

F2 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Mr. Dhingra's unvested RSUs were increased by 177 units as a result of such adjustment.

SEC source: 0001127602-25-008702 · form4.xml · derivative · entry 3

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,496

Underlying: Common Stock · 8,496 shares

Expires 2028-01-02

F4 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F4 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008702 · form4.xml · derivative · entry 2

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,496

Underlying: Common Stock · 8,496 shares

Expires 2028-01-02

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001127602-25-008702 · form4.xml · nonDerivative · entry 1

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,687

F1 · shares: Grant of restricted stock units shall vest as follows: 25% of the shares subject to the award shall vest on each of February 15, 2026, February 15, 2027, February 15, 2028, and February 15, 2029, subject to awardee's continuing status as a service provider on such dates.

F2 · balance_after: Balance includes 192 shares acquired through Employee Stock Purchase Plan.

SEC source: 0001127602-25-008700 · form4.xml · derivative · entry 3

Ericksen Scott D · CIK 0001950482 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,218

Underlying: Common Stock · 2,218 shares

Expires 2028-01-02

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008700 · form4.xml · derivative · entry 2

Ericksen Scott D · CIK 0001950482 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,218

Underlying: Common Stock · 2,218 shares

Expires 2028-01-02

F2 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F2 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001127602-25-008700 · form4.xml · nonDerivative · entry 1

Ericksen Scott D · CIK 0001950482 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,692

F1 · shares: Grant of restricted stock units shall vest as follows: 25% of the shares subject to the award shall vest on each of February 15, 2026, February 15, 2027, February 15, 2028, and February 15, 2029, subject to awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008699 · form4.xml · derivative · entry 3

Pegels Kevin Carl · CIK 0001892104 · Chief of Global Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,496

Underlying: Common Stock · 8,496 shares

Expires 2028-01-02

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008699 · form4.xml · derivative · entry 2

Pegels Kevin Carl · CIK 0001892104 · Chief of Global Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,496

Underlying: Common Stock · 8,496 shares

Expires 2028-01-02

F2 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F2 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001127602-25-008699 · form4.xml · nonDerivative · entry 1

Pegels Kevin Carl · CIK 0001892104 · Chief of Global Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,075

F1 · shares: Grant of restricted stock units shall vest as follows: 25% of the shares subject to the award shall vest on each of February 15, 2026, February 15, 2027, February 15, 2028, and February 15, 2029, subject to awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008696 · form4.xml · derivative · entry 3

Rollins Carissa · CIK 0001916557 · SVP, Chief Information Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,496

Underlying: Common Stock · 8,496 shares

Expires 2028-01-02

F4 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F4 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008696 · form4.xml · derivative · entry 2

Rollins Carissa · CIK 0001916557 · SVP, Chief Information Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,496

Underlying: Common Stock · 8,496 shares

Expires 2028-01-02

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001127602-25-008696 · form4.xml · nonDerivative · entry 1

Rollins Carissa · CIK 0001916557 · SVP, Chief Information Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,560

F1 · shares: Grant of restricted stock units shall vest as follows: 25% of the shares subject to the award shall vest on each of February 15, 2026, February 15, 2027, February 15, 2028, and February 15, 2029, subject to awardee's continuing status as a service provider on such dates.

F2 · balance_after: Balance includes 192 shares acquired through Employee Stock Purchase Plan.

SEC source: 0001127602-25-008695 · form4.xml · derivative · entry 3

Thaysen Jacob · CIK 0001625263 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,493

Underlying: Common Stock · 33,493 shares

Expires 2028-01-02

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008695 · form4.xml · derivative · entry 2

Thaysen Jacob · CIK 0001625263 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,493

Underlying: Common Stock · 33,493 shares

Expires 2028-01-02

F2 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F2 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001127602-25-008695 · form4.xml · nonDerivative · entry 1

Thaysen Jacob · CIK 0001625263 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,040

F1 · shares: Grant of restricted stock units shall vest as follows: 25% of the shares subject to the award shall vest on each of February 15, 2026, February 15, 2027, February 15, 2028, and February 15, 2029, subject to awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008692 · form4.xml · derivative · entry 3

Wedel Christensen Jakob · CIK 0002020721 · SVP, Strategy/Corp Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,516

Underlying: Common Stock · 7,516 shares

Expires 2028-01-02

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 2, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-008692 · form4.xml · derivative · entry 2

Wedel Christensen Jakob · CIK 0002020721 · SVP, Strategy/Corp Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,516

Underlying: Common Stock · 7,516 shares

Expires 2028-01-02

F2 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F2 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2025-2027 with vesting on January 2, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2025-2027, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001127602-25-008692 · form4.xml · nonDerivative · entry 1

Wedel Christensen Jakob · CIK 0002020721 · SVP, Strategy/Corp Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,741

F1 · shares: Grant of restricted stock units shall vest as follows: 25% of the shares subject to the award shall vest on each of February 15, 2026, February 15, 2027, February 15, 2028, and February 15, 2029, subject to awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-25-007589 · form4.xml · nonDerivative · entry 1

ARNOLD FRANCES · CIK 0001665419 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,127

F1 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Dr. Arnold's unvested RSUs were increased by 53 units as a result of such adjustment.

SEC source: 0001127602-25-005785 · form4.xml · nonDerivative · entry 1

Wedel Christensen Jakob · CIK 0002020721 · SVP, Strategy/Corp Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,299

SEC source: 0001127602-25-005784 · form4.xml · nonDerivative · entry 2

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,212

SEC source: 0001127602-25-005784 · form4.xml · nonDerivative · entry 1

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 13,968

SEC source: 0001127602-25-005780 · form4.xml · nonDerivative · entry 1

Davies Scott M · CIK 0002040663 · Interim General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,929

SEC source: 0001127602-25-005781 · form4.xml · nonDerivative · entry 1

Barnard Steven · CIK 0001990125 · SVP, Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 25,518

SEC source: 0001127602-25-005779 · form4.xml · nonDerivative · entry 1

Ericksen Scott D · CIK 0001950482 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,257

SEC source: 0001127602-25-005778 · form4.xml · nonDerivative · entry 1

Pegels Kevin Carl · CIK 0001892104 · Chief of Global Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,792

F1 · security: Includes unvested Restricted Stock Units granted prior to appointment as Section 16 Officer.

SEC source: 0001127602-25-005777 · form4.xml · nonDerivative · entry 1

Rollins Carissa · CIK 0001916557 · SVP, Chief Information Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,085

SEC source: 0001127602-25-005776 · form4.xml · nonDerivative · entry 1

Thaysen Jacob · CIK 0001625263 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 42,331

SEC source: 0001127602-25-000938 · form4.xml · nonDerivative · entry 1

Ericksen Scott D · CIK 0001950482 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 9,529

SEC source: 0001127602-25-000937 · form4.xml · nonDerivative · entry 1

Barnard Steven · CIK 0001990125 · SVP, Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 26,047

SEC source: 0001127602-25-000936 · form4.xml · nonDerivative · entry 1

Davies Scott M · CIK 0002040663 · Interim General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,336

SEC source: 0001127602-25-000935 · form4.xml · nonDerivative · entry 1

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,612

SEC source: 0001127602-25-000136 · form4.xml · nonDerivative · entry 1

Ullem Scott B. · CIK 0001446989 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,891

F1 · shares: Mr. Ullem elected to receive 100% of his 2024 board and committee cash retainer fees in Illumina stock. The number of shares issued in lieu of cash is based on the quotient of (i) the cash compensation otherwise payable for the immediately completed quarter divided by (ii) the volume weighted average closing price per share during the immediately completed quarter, calculated by reference to each trading day during such quarter. The amount reported on this Form represents Mr. Ullem's 4th quarter 2024 retainer fees.

SEC source: 0001127602-24-028864 · form4.xml · nonDerivative · entry 1

Wedel Christensen Jakob · CIK 0002020721 · SVP, Strategy/Corp Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,759

F1 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Mr. Wedel's unvested RSUs were increased by 142 units as a result of such adjustment.

SEC source: 0001127602-24-026774 · form4.xml · nonDerivative · entry 1

Davies Scott M · CIK 0002040663 · Interim General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,404

SEC source: 0001127602-24-026776 · form4.xml · nonDerivative · entry 1

Rollins Carissa · CIK 0001916557 · SVP, Chief Information Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,598

F1 · balance_after: Balance includes 62 shares acquired through Employee Stock Purchase Plan.

F2 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Ms. Rollin's unvested RSUs were increased by 202 units as a result of such adjustment.

SEC source: 0001127602-24-026775 · form4.xml · nonDerivative · entry 1

Barnard Steven · CIK 0001990125 · SVP, Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,115

SEC source: 0001127602-24-026773 · form4.xml · nonDerivative · entry 1

Ericksen Scott D · CIK 0001950482 · VP, Chief Accounting Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,597

F1 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Mr. Ericksen's unvested RSUs were increased by 150 units as a result of such adjustment.

SEC source: 0001127602-24-026772 · form4.xml · nonDerivative · entry 1

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,680

F1 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Ms. Leckman's unvested RSUs were increased by 245 units as a result of such adjustment.

SEC source: 0001127602-24-026771 · form4.xml · nonDerivative · entry 1

Pegels Kevin Carl · CIK 0001892104 · Chief of Global Operations

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,357

F1 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Mr. Pegels's unvested RSUs were increased by 210 units as a result of such adjustment.

SEC source: 0001127602-24-025339 · form4.xml · nonDerivative · entry 1

Thaysen Jacob · CIK 0001625263 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 44,395

F1 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Mr. Thaysen's unvested RSUs were increased by 746 units as a result of such adjustment.

SEC source: 0001127602-24-024722 · form4.xml · nonDerivative · entry 1

Ullem Scott B. · CIK 0001446989 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,733

F1 · shares: Mr. Ullem elected to receive 100% of his 2024 board and committee cash retainer fees in Illumina stock. The number of shares issued in lieu of cash is based on the quotient of (i) the cash compensation otherwise payable for the immediately completed quarter divided by (ii) the volume weighted average closing price per share during the immediately completed quarter, calculated by reference to each trading day during such quarter. The amount reported on this Form represents Mr. Ullem's 3rd quarter 2024 retainer fees.

SEC source: 0001127602-24-024096 · form4.xml · nonDerivative · entry 1

Dadswell Charles · CIK 0001575229 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Indirect · By The Charles Dadswell Trust

Disclosed balance after: 20,586

SEC source: 0001127602-24-023698 · form4.xml · nonDerivative · entry 1

Barnard Steven · CIK 0001990125 · SVP, Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 27,591

F1 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Mr. Barnard's unvested RSUs were increased by 296 units as a result of such adjustment.

SEC source: 0001127602-24-022485 · form4.xml · nonDerivative · entry 1

Dadswell Charles · CIK 0001575229 · SVP, General Counsel

10b5-1 filing: Plan reported

Ownership: Indirect · By The Charles Dadswell Trust

Disclosed balance after: 21,575

F1 · balance_after: In connection with Illumina's spin out of Grail, Inc., which was completed on June 24, 2024, all unvested equity award units were adjusted pursuant to Illumina's Amended and Restated 2015 Stock and Incentive Plan. Mr. Dadswell's unvested RSUs were increased by 266 units as a result of such adjustment.

SEC source: 0001127602-24-020256 · form4.xml · derivative · entry 7

Cunningham Everett · CIK 0001564777 · SVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,430

Underlying: Common Stock · 18,430 shares

Expires 2027-01-03

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 3, 2027. The number of shares issued will range from 0% to 200% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 3, 2027, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending January 3, 2027. The number of shares issued will range from 0% to 200% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending January 3, 2027, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001127602-24-020256 · form4.xml · derivative · entry 6

Cunningham Everett · CIK 0001564777 · SVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,430

Underlying: Common Stock · 18,430 shares

Expires 2027-01-03

F2 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2024-2026 with vesting on January 3, 2027 . The number of shares issued will range from 0% to 200% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2024-2026 , relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F2 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average operating margin for fiscal years 2024-2026 with vesting on January 3, 2027 . The number of shares issued will range from 0% to 200% of the amount specified above, based on the Company's actual three-year average operating margin for fiscal years 2024-2026 , relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.