ILMN

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 11

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,229,508

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $164.14 to $165.09.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 10

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,236,396

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $163.13 to $164.09.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 9

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,256,228

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $162.05 to $162.98.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 8

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,258,453

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $161.05 to $162.03.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 7

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,263,709

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $160.05 to $161.03.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 6

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,268,288

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $159.05 to $160.04.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001110803-26-000130 · form4.xml · nonDerivative · entry 1

Davies Scott M · CIK 0002040663 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,568

SEC source: 0001110803-26-000129 · form4.xml · nonDerivative · entry 2

Ericksen Scott D · CIK 0001950482 · VP, Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,446

SEC source: 0001011438-26-000371 · form4.xml · derivative · entry 21

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 0

Underlying: Common Stock · 24,562 shares

Expires 2028-02-11

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 28, 2026, upon final termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $3,841,496.80, representing $156.40 per share for each of the 24,562 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $2,525,464.84, representing $102.82 for each of such 24,562 notional shares.

F4 · kind: The final termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder.

F3 · price: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 28, 2026, upon final termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $3,841,496.80, representing $156.40 per share for each of the 24,562 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $2,525,464.84, representing $102.82 for each of such 24,562 notional shares.

F3 · derivative.exercise_date: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 28, 2026, upon final termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $3,841,496.80, representing $156.40 per share for each of the 24,562 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $2,525,464.84, representing $102.82 for each of such 24,562 notional shares.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 5

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,280,048

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $157.85 to $158.77.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,390,472

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $156.85 to $157.84.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,462,458

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $155.85 to $156.84. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (5)-(21) to this Form 4.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,500,048

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 28, 2026, upon final termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $3,841,496.80, representing $156.40 per share for each of the 24,562 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $2,525,464.84, representing $102.82 for each of such 24,562 notional shares.

F4 · kind: The final termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,524,610

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 28, 2026, upon final termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $3,841,496.80, representing $156.40 per share for each of the 24,562 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $2,525,464.84, representing $102.82 for each of such 24,562 notional shares.

F4 · kind: The final termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001110803-26-000129 · form4.xml · nonDerivative · entry 1

Ericksen Scott D · CIK 0001950482 · VP, Chief Accounting Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,946

SEC source: 0001110803-26-000121 · form4.xml · nonDerivative · entry 1

KING DAVID P · CIK 0001275654 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,072

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest on the earlier of (i) the one year anniversary of the date of grant of the award and (ii) the date immediately preceding the date of the annual meeting of the company's stockholders for the year following the year of grant of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000120 · form4.xml · nonDerivative · entry 1

SIEGEL SUSAN E · CIK 0001240363 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,535

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest on the earlier of (i) the one year anniversary of the date of grant of the award and (ii) the date immediately preceding the date of the annual meeting of the company's stockholders for the year following the year of grant of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000119 · form4.xml · nonDerivative · entry 1

Ullem Scott B. · CIK 0001446989 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,863

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest on the earlier of (i) the one year anniversary of the date of grant of the award and (ii) the date immediately preceding the date of the annual meeting of the company's stockholders for the year following the year of grant of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000118 · form4.xml · nonDerivative · entry 1

SCHILLER PHILIP W · CIK 0001214110 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,220

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest on the earlier of (i) the one year anniversary of the date of grant of the award and (ii) the date immediately preceding the date of the annual meeting of the company's stockholders for the year following the year of grant of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000117 · form4.xml · nonDerivative · entry 1

RICHO ANNA · CIK 0001199306 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,527

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest on the earlier of (i) the one year anniversary of the date of grant of the award and (ii) the date immediately preceding the date of the annual meeting of the company's stockholders for the year following the year of grant of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000116 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,638

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest the date prior to the annual meeting of the company's stockholders in the year of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000115 · form4.xml · nonDerivative · entry 1

Gottlieb Scott · CIK 0001411359 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 14,795

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest the date prior to the annual meeting of the company's stockholders in the year of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000114 · form4.xml · nonDerivative · entry 2

DORSA CAROLINE · CIK 0001181174 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 15,754

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest on the earlier of (i) the one year anniversary of the date of grant of the award and (ii) the date immediately preceding the date of the annual meeting of the company's stockholders for the year following the year of grant of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000114 · form4.xml · nonDerivative · entry 1

DORSA CAROLINE · CIK 0001181174 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,682

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 11

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,500,048

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $147.50 to $148.06.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 10

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,500,228

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $146.50 to $147.49.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 9

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,514,004

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $145.50 to $146.49.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 8

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,539,356

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $144.50 to $145.49.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 7

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,592,132

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $143.50 to $144.49.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 6

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,604,441

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $148 to $148.49.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 5

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,609,751

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $147 to $147.98.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,616,275

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $145.75 to $146.74.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,669,885

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $144.75 to $145.73. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (5)-(13) to this Form 4.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · derivative · entry 13

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 24,562

Underlying: Common Stock · 255,378 shares

Expires 2028-02-11

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F4 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 24,562 shares of common stock from the counterparty at $102.82 per share.

F3 · price: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F3 · derivative.exercise_date: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,829,508

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F4 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 24,562 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000335 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,084,886

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 12, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $36,942,981.48, representing $144.66 per share for each of the 255,378 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $26,257,965.96, representing $102.82 for each of such 255,378 notional shares.

F4 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 24,562 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · derivative · entry 7

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 279,940

Underlying: Common Stock · 79,568 shares

Expires 2028-02-11

F4 · kind: In addition, on May 11, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $11,414,029.60, representing $143.45 per share for each of the 79,568 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $8,181,181.76, representing $102.82 for each of such 79,568 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F4 · price: In addition, on May 11, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $11,414,029.60, representing $143.45 per share for each of the 79,568 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $8,181,181.76, representing $102.82 for each of such 79,568 notional shares.

F3 · derivative.exercise_date: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,829,508

F4 · kind: In addition, on May 11, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $11,414,029.60, representing $143.45 per share for each of the 79,568 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $8,181,181.76, representing $102.82 for each of such 79,568 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,909,076

F4 · kind: In addition, on May 11, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $11,414,029.60, representing $143.45 per share for each of the 79,568 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $8,181,181.76, representing $102.82 for each of such 79,568 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · derivative · entry 6

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 359,508

Underlying: Common Stock · 9,236 shares

Expires 2028-02-11

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F3 · price: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F3 · derivative.exercise_date: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,829,508

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000273 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,838,744

F3 · kind: As previously reported, the Corvex Funds had entered into equity swaps that represented an aggregate economic long-side exposure comparable to a notional interest in 368,744 shares of common stock of the Issuer. Under the terms of the swaps, the value to be received or paid upon termination of a swap will be determined by the difference in the market price per notional share of common stock on the date of termination as compared to the cost of such notional share of common stock at the time of entry into the swap. On May 7, 2026, upon partial termination of the swaps as reported in Table II above, the swaps counterparty paid to the Corvex Funds $1,295,349, representing $140.25 per share for each of the 9,236 notional shares subject to the termination (the market price of the common stock on the date of the partial termination), offset by $949,645.52, representing $102.82 for each of such 9,236 notional shares.

F5 · kind: The partial termination of the equity swaps and the reported purchases of common stock in connection therewith are deemed exempt from Section 16(b) of the Securities Exchange Act of 1934 pursuant to Rule 16b-6(b) thereunder. The remaining swaps terminate on February 11, 2028, and have a cost basis of $102.82 per notional share of common stock. All balances will be settled in cash by default. At the option of the Corvex Funds, the remaining portion of the swaps may be physically settled by the Corvex Funds acquiring 279,940 shares of common stock from the counterparty at $102.82 per share.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001110803-26-000094 · form4.xml · nonDerivative · entry 2

Wedel Christensen Jakob · CIK 0002020721 · SVP, Strategy/Corp Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,056

SEC source: 0001110803-26-000094 · form4.xml · nonDerivative · entry 1

Wedel Christensen Jakob · CIK 0002020721 · SVP, Strategy/Corp Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 15,756

SEC source: 0001110803-26-000084 · form4.xml · nonDerivative · entry 1

Ullem Scott B. · CIK 0001446989 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,791

F1 · shares: Mr. Ullem elected to receive 100% of his 2026 board and committee cash retainer fees in Illumina stock. The number of shares issued in lieu of cash is based on the quotient of (i) the cash compensation otherwise payable for the immediately completed quarter divided by (ii) the volume weighted average closing price per share during the immediately completed quarter, calculated by reference to each trading day during such quarter. The amount reported on this Form represents Mr. Ullem's 1st quarter 2026 retainer fees.

SEC source: 0001110803-26-000083 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,566

F1 · shares: Mr. Meister elected to receive 100% of his 2026 board and committee cash retainer fees in Illumina stock. The number of shares issued in lieu of cash is based on the quotient of (i) the cash compensation otherwise payable for the immediately completed quarter divided by (ii) the volume weighted average closing price per share during the immediately completed quarter, calculated by reference to each trading day during such quarter. The amount reported on this Form represents Mr. Meister's 1st quarter 2026 retainer fees.

SEC source: 0001110803-26-000074 · form4.xml · derivative · entry 3

Barnard Steven · CIK 0001990125 · SVP, Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,871

Underlying: Common Stock · 8,871 shares

Expires 2028-12-31

F4 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending December 31, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F4 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending December 31, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001110803-26-000074 · form4.xml · derivative · entry 2

Barnard Steven · CIK 0001990125 · SVP, Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,871

Underlying: Common Stock · 8,871 shares

Expires 2028-12-31

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average consolidated non-GAAP earnings per share growth for fiscal years 2026-2028 with vesting on December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average consolidated non-GAAP earnings per share growth for fiscal years 2026-2028, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average consolidated non-GAAP earnings per share growth for fiscal years 2026-2028 with vesting on December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average consolidated non-GAAP earnings per share growth for fiscal years 2026-2028, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001110803-26-000074 · form4.xml · nonDerivative · entry 1

Barnard Steven · CIK 0001990125 · SVP, Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 41,335

F1 · shares: Grant of restricted stock units shall vest as follows: 25% of the shares subject to the award shall vest on each of February 15, 2027, February 15, 2028, February 15, 2029, and February 15, 2030, subject to awardee's continuing status as a service provider on such dates.

F2 · balance_after: Balance includes 297 shares acquired through Employee Stock Purchase Plan.

SEC source: 0001110803-26-000073 · form4.xml · derivative · entry 3

Davies Scott M · CIK 0002040663 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,824

Underlying: Common Stock · 6,824 shares

Expires 2028-12-31

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending December 31, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending December 31, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.