ILMN

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 11

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,821,261

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $213.14 to $214.13.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 10

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,893,200

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $212.14 to $213.12.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 9

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,923,005

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $211.14 to $212.13.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 8

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,957,014

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $210.11 to $211.09.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 7

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,980,652

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $209.11 to $210.10.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 6

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,989,730

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $208.02 to $209.01.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 5

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,993,293

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $207.01 to $207.91.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 1,994,425

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $204.72 to $205.11.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,007,238

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $203.65 to $204.61.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,011,997

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $202.59 to $203.58.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-361476 · ownership.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,069,541

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $201.59 to $202.58. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (3)-(30) to this Form 4.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001110803-26-000173 · form4.xml · nonDerivative · entry 1

Wedel Christensen Jakob · CIK 0002020721 · SVP, Strategy/Corp Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 14,023

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 14

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,089,425

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $202.60 to $203.50.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 13

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,091,875

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $201.60 to $202.58.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 12

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,103,247

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $200.60 to $201.59.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 11

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,133,645

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $199.60 to $200.59.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 10

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,252,398

F13 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $198.60 to $199.59.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 9

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,320,445

F12 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $197.60 to $198.59.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001110803-26-000169 · form4.xml · derivative · entry 3

Sullivan Michael C · CIK 0002147356 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,254

Underlying: Common Stock · 5,254 shares

Expires 2028-12-31

F3 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending December 31, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

F3 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's relative total shareholder return for the fiscal year ending December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the company's relative total shareholder return for the fiscal year ending December 31, 2028, relative to pre-defined objectives, subject to the awardee's continuing status as a service provider on such dates.

SEC source: 0001110803-26-000169 · form4.xml · derivative · entry 2

Sullivan Michael C · CIK 0002147356 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,254

Underlying: Common Stock · 5,254 shares

Expires 2028-12-31

F2 · derivative.exercise_price: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average consolidated non-GAAP earnings per share growth for fiscal years 2026-2028 with vesting on December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average consolidated non-GAAP earnings per share growth for fiscal years 2026-2028, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

F2 · derivative.exercise_date: Each performance stock unit represents a contingent right to receive one share of common stock based on the Company's three-year average consolidated non-GAAP earnings per share growth for fiscal years 2026-2028 with vesting on December 31, 2028. The number of shares issued will range from 0% to 250% of the amount specified above, based on the Company's actual three-year average consolidated non-GAAP earnings per share growth for fiscal years 2026-2028, relative to pre-defined objectives, subject to awardee's continuing to be a service provider on such dates.

SEC source: 0001110803-26-000169 · form4.xml · nonDerivative · entry 1

Sullivan Michael C · CIK 0002147356 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 4,503

F1 · shares: Grant of restricted stock units with 25% of the shares subject to the award vesting on each of the first, second, third and fourth anniversaries of the date of grant, subject to the awardee's continuing to be a service provider on such dates.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 8

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,372,694

F11 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $203.00 to $203.44.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 7

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,440,682

F10 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $202.00 to $202.99.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 6

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,488,868

F9 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $201.00 to $201.99.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 5

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,556,593

F8 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $200.00 to $200.99.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 4

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,593,835

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $199.00 to $199.96.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 3

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,628,995

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $198.00 to $198.98.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 2

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,795,496

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $197.00 to $197.99.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001193125-26-338361 · ownership.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,823,350

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $196.00 to $196.99. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (3) and (5) to (17) to this Form 4.

F4 · balance_after: Our Section 16 filings inadvertently reported that the reporting person indirectly owned 100 fewer shares of common stock. The correct number of shares indirectly owned prior to the sales reported on this filing was 2,830,552 shares of common stock. The amount reported in Column 5 reflects such correction.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001110803-26-000161 · form4.xml · nonDerivative · entry 1

Davies Scott M · CIK 0002040663 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,338

SEC source: 0001110803-26-000148 · form4.xml · nonDerivative · entry 1

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 6,780

F1 · shares: Mr. Meister elected to receive 100% of his 2026 board and committee cash retainer fees in Illumina stock. The number of shares issued in lieu of cash is based on the quotient of (i) the cash compensation otherwise payable for the immediately completed quarter divided by (ii) the volume weighted average closing price per share during the immediately completed quarter, calculated by reference to each trading day during such quarter. The amount reported on this Form represents Mr. Meister's 2nd quarter 2026 retainer fees.

SEC source: 0001110803-26-000147 · form4.xml · nonDerivative · entry 1

Ullem Scott B. · CIK 0001446989 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 11,030

F1 · shares: Mr. Ullem elected to receive 100% of his 2026 board and committee cash retainer fees in Illumina stock. The number of shares issued in lieu of cash is based on the quotient of (i) the cash compensation otherwise payable for the immediately completed quarter divided by (ii) the volume weighted average closing price per share during the immediately completed quarter, calculated by reference to each trading day during such quarter. The amount reported on this Form represents Mr. Ullem's 2nd quarter 2026 retainer fees.

SEC source: 0001110803-26-000144 · form4.xml · nonDerivative · entry 1

Davies Scott M · CIK 0002040663 · Chief Legal Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 20,953

SEC source: 0001110803-26-000142 · form4.xml · nonDerivative · entry 1

Skovronsky Daniel · CIK 0001741474 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,674

F1 · shares: Grant of restricted stock units. 100% of the shares subject to the restricted stock unit award shall vest on the earlier of (i) the one year anniversary of the date of grant of the award and (ii) the date immediately preceding the date of the annual meeting of the company's stockholders for the year following the year of grant of the award, provided, in each case, that the awardee continues to serve as a director on such date.

SEC source: 0001110803-26-000134 · form4.xml · nonDerivative · entry 5

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,259

SEC source: 0001110803-26-000134 · form4.xml · nonDerivative · entry 4

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,261

SEC source: 0001110803-26-000134 · form4.xml · nonDerivative · entry 3

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,300

F3 · price: Weighted average sale price representing 78 shares sold ranging from $163.35 to $163.36 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

SEC source: 0001110803-26-000134 · form4.xml · nonDerivative · entry 2

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,378

F2 · price: Weighted average sale price representing 374 shares sold ranging from $162.31 to $163.25 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

SEC source: 0001110803-26-000134 · form4.xml · nonDerivative · entry 1

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 21,752

F1 · price: Weighted average sale price representing 290 shares sold ranging from $161.30 to $162.19 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

SEC source: 0001110803-26-000132 · form4.xml · nonDerivative · entry 3

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,042

F3 · price: Weighted average sale price representing 290 shares sold ranging from $162.66 to $163.33 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

SEC source: 0001110803-26-000132 · form4.xml · nonDerivative · entry 2

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,332

F2 · price: Weighted average sale price representing 318 shares sold ranging from $161.65 to $162.26 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

SEC source: 0001110803-26-000132 · form4.xml · nonDerivative · entry 1

Leckman Patricia · CIK 0002015062 · SVP, Chief People Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 22,650

F1 · price: Weighted average sale price representing 176 shares sold ranging from $160.30 to $161.24 per share. Number of shares sold at each separate price will be made available to the SEC staff, the issuer, or a security holder of the issuer upon request.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 19

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,830,452

F21 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $165.00 to $165.95.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 18

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,845,924

F20 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $164.00 to $164.99.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 17

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,933,577

F19 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $163.00 to $163.99.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 16

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,995,190

F18 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $162.00 to $162.99.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 15

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,065,452

F17 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $165.20 to $165.43.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 14

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,067,413

F16 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $164.19 to $165.18.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 13

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,160,290

F15 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $163.19 to $164.18.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.

SEC source: 0001011438-26-000371 · form4.xml · nonDerivative · entry 12

Meister Keith A. · CIK 0001307631 · Director

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,166,488

F14 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions within the range of $162.19 to $163.16.

F1 · ownership.nature: These securities of Illumina, Inc. (the "Issuer") are held for the accounts of certain private investment funds (collectively, the "Corvex Funds") for which Corvex Management LP ("Corvex") acts as investment adviser, including Corvex Master Fund LP and Corvex Select Equity Master Fund LP. The general partner of Corvex is controlled by Keith Meister.

F2 · ownership.nature: For the purposes of this filing, each of Corvex and Mr. Meister disclaims beneficial ownership of the reported securities except to the extent of his or its pecuniary interest therein. This filing shall not be deemed an admission that Corvex or Mr. Meister is the beneficial owner of any of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise.