Last 12 months
Inside the activity.
0 purchase rows · 0 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 0 |
| Dec 2025 | 0 | 0 |
| Jan 2026 | 0 | 0 |
| Feb 2026 | 0 | 0 |
| Mar 2026 | 0 | 0 |
| Apr 2026 | 0 | 0 |
| May 2026 | 0 | 0 |
| Jun 2026 | 0 | 0 |
| Jul 2026 | 0 | 0 |
| Aug 2026 | 0 | 0 |
| Sep 2026 | 0 | 0 |
| Oct 2026 | 0 | 0 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| September 21, 2026 Filed Sep 22, 2026 21:59 UTC |
Coll Crespo BlasCHIEF MEDICAL OFFICER
|
SaleAmerican Depositary Shares · Derivative | 4,008 | $36.15 | $144,872.77 |
DisclosureSEC source: 0002037144-26-000004 · form4-09222026_090944.xml · derivative · entry 4 Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 1,157 Underlying: Ordinary Shares · 12,024 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F6 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 30, 2026. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 21:59 UTC |
Coll Crespo BlasCHIEF MEDICAL OFFICER
|
ConversionAmerican Depositary Shares · Derivative | 4,008 | $0.00 | $0.00 |
DisclosureSEC source: 0002037144-26-000004 · form4-09222026_090944.xml · derivative · entry 3 Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 5,165 Underlying: Ordinary Shares · 12,024 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F4 · shares: 12,024 Ordinary Shares were converted into 4,008 American Depositary Shares as reported in Table II. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| September 21, 2026 Filed Sep 22, 2026 21:59 UTC |
Coll Crespo BlasCHIEF MEDICAL OFFICER
|
ConversionOrdinary Shares | 12,024 | $0.00 | $0.00 |
DisclosureSEC source: 0002037144-26-000004 · form4-09222026_090944.xml · nonDerivative · entry 2 Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 258,228 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F4 · shares: 12,024 Ordinary Shares were converted into 4,008 American Depositary Shares as reported in Table II. Read SEC document |
| September 18, 2026 Filed Sep 22, 2026 21:59 UTC |
Coll Crespo BlasCHIEF MEDICAL OFFICER
|
Tax withholdingOrdinary Shares | 10,626 | $11.67 | $124,005.42 |
DisclosureSEC source: 0002037144-26-000004 · form4-09222026_090944.xml · nonDerivative · entry 1 Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 270,252 F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer. F2 · shares: Represents shares withheld by the Issuer to satisfy income tax obligations associated with the vesting of a restricted share unit award. F3 · price: Reflects price per share in Ordinary Shares. Read SEC document |
| September 01, 2026 Filed Sep 3, 2026 01:18 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 100 | $47.83 | $4,783.00 |
DisclosureSEC source: 0001962926-26-000009 · form4-09032026_010924.xml · derivative · entry 7 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 0 Underlying: Ordinary Shares · 100 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| September 01, 2026 Filed Sep 3, 2026 01:18 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 4,539 | $47.20 | $214,254.42 |
DisclosureSEC source: 0001962926-26-000009 · form4-09032026_010924.xml · derivative · entry 6 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 100 Underlying: Ordinary Shares · 4,539 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F10 · price: The weighted average sale price for the transaction reported was $47.2030, and the range of prices were between $46.80 and $47.76. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| September 01, 2026 Filed Sep 3, 2026 01:18 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 1,300 | $45.86 | $59,623.46 |
DisclosureSEC source: 0001962926-26-000009 · form4-09032026_010924.xml · derivative · entry 5 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 4,639 Underlying: Ordinary Shares · 1,300 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F9 · price: The weighted average sale price for the transaction reported was $45.8642 and the range of prices were between $45.63 and $46.38. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| September 01, 2026 Filed Sep 3, 2026 01:18 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionAmerican Depositary Shares · Derivative | 5,939 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000009 · form4-09032026_010924.xml · derivative · entry 4 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 5,939 Underlying: Ordinary Shares · 5,939 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F6 · shares: 17,817 Ordinary Shares, which were acquired upon exercise of a share option, were converted into 5,939 American Depositary Shares. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| September 01, 2026 Filed Sep 3, 2026 01:18 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionShare Option (right to buy) · Derivative | 17,817 | $0.00 Strike: $0.34 | $0.00 |
DisclosureSEC source: 0001962926-26-000009 · form4-09032026_010924.xml · derivative · entry 3 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 125,081 Underlying: Ordinary Shares · 17,817 shares Expires 2029-09-10 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Reflects price per share in Ordinary Shares. F3 · derivative.exercise_date: 1/4 of the Ordinary Shares vested one year after July 22, 2019 (the "Vesting Commencement Date"); the balance of the Ordinary Shares vested in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date. F4 · balance_after: This reflects the number of Ordinary Shares remaining under the share option following the partial exercise of the share option for 17,817 Ordinary Shares. Read SEC document |
| September 01, 2026 Filed Sep 3, 2026 01:18 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionOrdinary Shares | 17,817 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000009 · form4-09032026_010924.xml · nonDerivative · entry 2 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 228,960 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · shares: The Ordinary Shares were converted into American Depositary Shares as reported in Table II. Read SEC document |
| September 01, 2026 Filed Sep 3, 2026 01:18 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionOrdinary Shares | 17,817 | $0.34 | $6,057.78 |
DisclosureSEC source: 0001962926-26-000009 · form4-09032026_010924.xml · nonDerivative · entry 1 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 246,777 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Reflects price per share in Ordinary Shares. Read SEC document |
| August 18, 2026 Filed Aug 20, 2026 00:23 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 400 | $55.05 | $22,020.00 |
DisclosureSEC source: 0001962926-26-000008 · form4-08202026_120854.xml · derivative · entry 7 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 0 Underlying: Ordinary Shares · 1,200 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F11 · price: The weighted average sale price for the transaction reported was $55.05 and the range of prices were between $54.85 and $55.15. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| August 18, 2026 Filed Aug 20, 2026 00:23 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 519 | $54.20 | $28,128.24 |
DisclosureSEC source: 0001962926-26-000008 · form4-08202026_120854.xml · derivative · entry 6 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 400 Underlying: Ordinary Shares · 1,557 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F10 · price: The weighted average sale price for the transaction reported was $54.1970, and the range of prices were between $53.80 and $54.7950. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| August 18, 2026 Filed Aug 20, 2026 00:23 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 3,020 | $53.13 | $160,461.66 |
DisclosureSEC source: 0001962926-26-000008 · form4-08202026_120854.xml · derivative · entry 5 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 919 Underlying: Ordinary Shares · 9,060 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F9 · price: The weighted average sale price for the transaction reported was $53.133 and the range of prices were between $52.77 and $53.70. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| August 18, 2026 Filed Aug 20, 2026 00:23 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionAmerican Depositary Shares · Derivative | 3,939 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000008 · form4-08202026_120854.xml · derivative · entry 4 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 3,939 Underlying: Ordinary Shares · 11,817 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F6 · shares: 11,817 Ordinary Shares, which were acquired upon exercise of a share option, were converted into 3,939 American Depositary Shares. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| August 18, 2026 Filed Aug 20, 2026 00:23 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionShare Option (right to buy) · Derivative | 11,817 | $0.00 Strike: $0.34 | $0.00 |
DisclosureSEC source: 0001962926-26-000008 · form4-08202026_120854.xml · derivative · entry 3 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 142,898 Underlying: Ordinary Shares · 11,817 shares Expires 2029-09-10 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Reflects price per share in Ordinary Shares. F3 · derivative.exercise_date: 1/4 of the Ordinary Shares vested one year after July 22, 2019 (the "Vesting Commencement Date"); the balance of the Ordinary Shares vested in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date. F4 · balance_after: This reflects the number of Ordinary Shares remaining under the share option following the partial exercise of the share option for 11,817 Ordinary Shares. Read SEC document |
| August 18, 2026 Filed Aug 20, 2026 00:23 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionOrdinary Shares | 11,817 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000008 · form4-08202026_120854.xml · nonDerivative · entry 2 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 228,960 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · shares: The Ordinary Shares were converted into American Depositary Shares as reported in Table II. Read SEC document |
| August 18, 2026 Filed Aug 20, 2026 00:23 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionOrdinary Shares | 11,817 | $0.34 | $4,017.78 |
DisclosureSEC source: 0001962926-26-000008 · form4-08202026_120854.xml · nonDerivative · entry 1 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 240,777 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Reflects price per share in Ordinary Shares. Read SEC document |
| August 06, 2026 Filed Aug 7, 2026 20:08 UTC |
Berrios John JosephChief Commercial Officer
|
GrantShare option (right to buy) · Derivative | 174,612 | $0.00 Strike: $17.54 | $0.00 |
DisclosureSEC source: 0002148420-26-000006 · form4-08072026_080836.xml · derivative · entry 2 Berrios John Joseph · CIK 0002148420 · Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 174,612 Underlying: Ordinary Shares · 174,612 shares Expires 2036-08-05 F3 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs. F4 · derivative.exercise_date: One-fourth of the shares vest on the first anniversary of August 6, 2026, and the remaining shares shall vest in thirty-six (36) equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date. F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
| August 06, 2026 Filed Aug 7, 2026 20:08 UTC |
Berrios John JosephChief Commercial Officer
|
GrantOrdinary Shares | 140,766 | $0.00 | $0.00 |
DisclosureSEC source: 0002148420-26-000006 · form4-08072026_080836.xml · nonDerivative · entry 1 Berrios John Joseph · CIK 0002148420 · Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 140,766 F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer. F2 · kind: Represents the grant of restricted share units ("RSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer. The RSUs vest 1/4th annually on each anniversary of August 6, 2026, subject to Reporting Person's continued service on such dates. Read SEC document |
| August 04, 2026 Filed Aug 5, 2026 20:49 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 839 | $50.03 | $41,974.33 |
DisclosureSEC source: 0001962926-26-000007 · form4-08052026_080829.xml · derivative · entry 6 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 0 Underlying: Ordinary Shares · 2,517 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F10 · price: The weighted average sale price for the transaction reported was $50.0290, and the range of prices were between $49.69 and $50.33. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| August 04, 2026 Filed Aug 5, 2026 20:49 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 3,100 | $49.29 | $152,785.67 |
DisclosureSEC source: 0001962926-26-000007 · form4-08052026_080829.xml · derivative · entry 5 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 839 Underlying: Ordinary Shares · 9,300 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F9 · price: The weighted average sale price for the transaction reported was $49.2857 and the range of prices were between $48.66 and $49.65. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| August 04, 2026 Filed Aug 5, 2026 20:49 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionAmerican Depositary Shares · Derivative | 3,939 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000007 · form4-08052026_080829.xml · derivative · entry 4 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 3,939 Underlying: Ordinary Shares · 11,817 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F6 · shares: 11,817 Ordinary Shares, which were acquired upon exercise of a share option, were converted into 3,939 American Depositary Shares. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| August 04, 2026 Filed Aug 5, 2026 20:49 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionShare Option (right to buy) · Derivative | 11,817 | $0.00 Strike: $0.34 | $0.00 |
DisclosureSEC source: 0001962926-26-000007 · form4-08052026_080829.xml · derivative · entry 3 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 154,715 Underlying: Ordinary Shares · 11,817 shares Expires 2029-09-10 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Reflects price per share in Ordinary Shares. F3 · derivative.exercise_date: 1/4 of the Ordinary Shares vested one year after July 22, 2019 (the "Vesting Commencement Date"); the balance of the Ordinary Shares vested in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date. F4 · balance_after: This reflects the number of Ordinary Shares remaining under the share option following the partial exercise of the share option for 11,817 Ordinary Shares. Read SEC document |
| August 04, 2026 Filed Aug 5, 2026 20:49 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionOrdinary Shares | 11,817 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000007 · form4-08052026_080829.xml · nonDerivative · entry 2 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 228,960 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · shares: The Ordinary Shares were converted into American Depositary Shares as reported in Table II. Read SEC document |
| August 04, 2026 Filed Aug 5, 2026 20:49 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionOrdinary Shares | 11,817 | $0.34 | $4,017.78 |
DisclosureSEC source: 0001962926-26-000007 · form4-08052026_080829.xml · nonDerivative · entry 1 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 240,777 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Reflects price per share in Ordinary Shares. Read SEC document |
| July 22, 2026 Filed Jul 24, 2026 13:11 UTC |
FMR LLC10% owner · See Remark 1
|
SaleAmerican Depositary Shares · Derivative | 16,085 | $50.07 | $805,375.95 |
DisclosureSEC source: 0001193125-26-315240 · ownership.xml · derivative · entry 5 FMR LLC · CIK 0000315066 · 10% owner · See Remark 1 10b5-1 filing: No plan indicated Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP Disclosed balance after: 16,086 Underlying: Ordinary Shares · 48,255 shares Expires not disclosed F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. F2 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $50.05 to $50.20. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information. F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Read SEC document |
| July 22, 2026 Filed Jul 24, 2026 13:11 UTC |
FMR LLC10% owner · See Remark 1
|
SaleAmerican Depositary Shares · Derivative | 1,367 | $50.07 | $68,445.69 |
DisclosureSEC source: 0001193125-26-315240 · ownership.xml · derivative · entry 4 FMR LLC · CIK 0000315066 · 10% owner · See Remark 1 10b5-1 filing: No plan indicated Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP Disclosed balance after: 1,369 Underlying: Ordinary Shares · 4,101 shares Expires not disclosed F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. F2 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $50.05 to $50.20. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information. F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Read SEC document |
| July 14, 2026 Filed Jul 15, 2026 22:57 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 1,600 | $51.71 | $82,734.08 |
DisclosureSEC source: 0001962926-26-000006 · form4-07152026_100751.xml · derivative · entry 6 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 0 Underlying: Ordinary Shares · 4,800 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F10 · price: The weighted average sale price for the transaction reported was $51.7088, and the range of prices were between $51.32 and $52.27. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| July 14, 2026 Filed Jul 15, 2026 22:57 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 6,278 | $50.80 | $318,894.78 |
DisclosureSEC source: 0001962926-26-000006 · form4-07152026_100751.xml · derivative · entry 5 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 1,600 Underlying: Ordinary Shares · 18,834 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F9 · price: The weighted average sale price for the transaction reported was $50.7956 and the range of prices were between $50.31 and $51.30. Upon request by the SEC staff, the Issuer, or any security holder of the Issuer, full information regarding the number of American Depositary Shares sold at each price will be provided. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| July 14, 2026 Filed Jul 15, 2026 22:57 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionAmerican Depositary Shares · Derivative | 7,878 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000006 · form4-07152026_100751.xml · derivative · entry 4 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 7,878 Underlying: Ordinary Shares · 23,634 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F6 · shares: 23,634 Ordinary Shares, which were acquired upon exercise of a share option, were converted into 7,878 American Depositary Shares. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| July 14, 2026 Filed Jul 15, 2026 22:57 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionShare Option (right to buy) · Derivative | 23,634 | $0.00 Strike: $0.34 | $0.00 |
DisclosureSEC source: 0001962926-26-000006 · form4-07152026_100751.xml · derivative · entry 3 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 166,532 Underlying: Ordinary Shares · 23,634 shares Expires 2029-09-10 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Reflects price per share in Ordinary Shares. F3 · derivative.exercise_date: 1/4 of the Ordinary Shares vested one year after July 22, 2019 (the "Vesting Commencement Date"); the balance of the Ordinary Shares vested in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date. F4 · balance_after: This reflects the number of Ordinary Shares remaining under the share option following the partial exercise of the share option for 23,634 Ordinary Shares. Read SEC document |
| July 14, 2026 Filed Jul 15, 2026 22:57 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionOrdinary Shares | 23,634 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000006 · form4-07152026_100751.xml · nonDerivative · entry 2 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 228,960 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · shares: The Ordinary Shares were converted into American Depositary Shares as reported in Table II. Read SEC document |
| July 14, 2026 Filed Jul 15, 2026 22:57 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionOrdinary Shares | 23,634 | $0.34 | $8,035.56 |
DisclosureSEC source: 0001962926-26-000006 · form4-07152026_100751.xml · nonDerivative · entry 1 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 252,594 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Reflects price per share in Ordinary Shares. Read SEC document |
| June 25, 2026 Filed Jun 30, 2026 00:32 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
SaleAmerican Depositary Shares · Derivative | 7,878 | $49.08 | $386,645.94 |
DisclosureSEC source: 0001962926-26-000005 · form4-06302026_120631.xml · derivative · entry 5 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 0 Underlying: Ordinary Shares · 23,634 shares Expires not disclosed F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F7 · kind: The American Depositary Shares were sold pursuant to a Rule 10b5-1 trading plan entered into on March 26, 2026. F8 · price: Reflects price per share in American Depositary Shares. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| June 25, 2026 Filed Jun 30, 2026 00:32 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionAmerican Depositary Shares · Derivative | 7,878 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000005 · form4-06302026_120631.xml · derivative · entry 4 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 7,878 Underlying: Ordinary Shares · 23,634 shares Expires not disclosed Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F5 · derivative.exercise_price: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F6 · shares: 23,634 Ordinary Shares, which were acquired upon exercise of a share option, were converted into 7,878 American Depositary Shares. F5 · derivative.exercise_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. F5 · derivative.expiration_date: Each American Depositary Share is convertible at any time, at the holder's election, into three Ordinary Shares of the Issuer. The American Depositary Shares have no expiration date. Read SEC document |
| June 25, 2026 Filed Jun 30, 2026 00:32 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionShare Option (right to buy) · Derivative | 23,634 | $0.00 Strike: $0.34 | $0.00 |
DisclosureSEC source: 0001962926-26-000005 · form4-06302026_120631.xml · derivative · entry 3 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 190,166 Underlying: Ordinary Shares · 23,634 shares Expires 2029-09-10 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_price: Reflects price per share in Ordinary Shares. F3 · derivative.exercise_date: 1/4 of the Ordinary Shares vested one year after July 22, 2019 (the "Vesting Commencement Date"); the balance of the Ordinary Shares vested in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date. F4 · balance_after: This reflects the number of Ordinary Shares remaining under the share option following the partial exercise of the share option for 23,634 Ordinary Shares. Read SEC document |
| June 25, 2026 Filed Jun 30, 2026 00:32 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
ConversionOrdinary Shares | 23,634 | $0.00 | $0.00 |
DisclosureSEC source: 0001962926-26-000005 · form4-06302026_120631.xml · nonDerivative · entry 2 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 228,960 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F2 · shares: The Ordinary Shares were converted into American Depositary Shares as reported in Table II. Read SEC document |
| June 25, 2026 Filed Jun 30, 2026 00:32 UTC |
Lin XichenCHIEF SCIENTIFIC OFFICER
|
Exercise / conversionOrdinary Shares | 23,634 | $0.34 | $8,035.56 |
DisclosureSEC source: 0001962926-26-000005 · form4-06302026_120631.xml · nonDerivative · entry 1 Lin Xichen · CIK 0001962926 · CHIEF SCIENTIFIC OFFICER 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 252,594 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · price: Reflects price per share in Ordinary Shares. Read SEC document |
| June 17, 2026 Filed Jun 18, 2026 21:00 UTC |
WELCH DANIEL GDirector
|
GrantShare Option (right to buy) · Derivative | 39,453 | $0.00 Strike: $15.00 | $0.00 |
DisclosureSEC source: 0001206199-26-000002 · form4-06182026_050603.xml · derivative · entry 1 WELCH DANIEL G · CIK 0001206199 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 39,453 Underlying: Ordinary Shares · 39,453 shares Expires 2036-06-16 F1 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's American Depositary Shares ("ADSs"). F2 · derivative.exercise_date: The shares vest in equal monthly installments over the 12 months following June 17, 2026, provided that the grant will in any case be fully vested on the date immediately prior to the date of the Issuer's 2027 annual shareholder meeting, F3 · derivative.underlying_shares: The Ordinary Shares of the Issuer may be represented by ADSs. Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
| June 17, 2026 Filed Jun 18, 2026 21:00 UTC |
LOVE TED WDirector
|
GrantShare Option (right to buy) · Derivative | 39,453 | $0.00 Strike: $15.00 | $0.00 |
DisclosureSEC source: 0001188919-26-000010 · form4-06182026_050611.xml · derivative · entry 1 LOVE TED W · CIK 0001188919 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 39,453 Underlying: Ordinary Shares · 39,453 shares Expires 2036-06-16 F1 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's American Depositary Shares ("ADSs"). F2 · derivative.exercise_date: The shares vest in equal monthly installments over the 12 months following June 17, 2026, provided that the grant will in any case be fully vested on the date immediately prior to the date of the Issuer's 2027 annual shareholder meeting, F3 · derivative.underlying_shares: The Ordinary Shares of the Issuer may be represented by ADSs. Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
| June 17, 2026 Filed Jun 18, 2026 21:00 UTC |
DOBMEIER ERICDirector
|
GrantShare Option (right to buy) · Derivative | 39,453 | $0.00 Strike: $15.00 | $0.00 |
DisclosureSEC source: 0001202785-26-000004 · form4-06182026_050606.xml · derivative · entry 1 DOBMEIER ERIC · CIK 0001202785 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 39,453 Underlying: Ordinary Shares · 39,453 shares Expires 2036-06-16 F1 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's American Depositary Shares ("ADSs"). F2 · derivative.exercise_date: The shares vest in equal monthly installments over the 12 months following June 17, 2026, provided that the grant will in any case be fully vested on the date immediately prior to the date of the Issuer's 2027 annual shareholder meeting, F3 · derivative.underlying_shares: The Ordinary Shares of the Issuer may be represented by ADSs. Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
| June 17, 2026 Filed Jun 18, 2026 21:00 UTC |
TETLOW SHARONDirector
|
GrantShare Option (right to buy) · Derivative | 39,453 | $0.00 Strike: $15.00 | $0.00 |
DisclosureSEC source: 0001328565-26-000002 · form4-06182026_050604.xml · derivative · entry 1 TETLOW SHARON · CIK 0001328565 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 39,453 Underlying: Ordinary Shares · 39,453 shares Expires 2036-06-16 F1 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's American Depositary Shares ("ADSs"). F2 · derivative.exercise_date: The shares vest in equal monthly installments over the 12 months following June 17, 2026, provided that the grant will in any case be fully vested on the date immediately prior to the date of the Issuer's 2027 annual shareholder meeting, F3 · derivative.underlying_shares: The Ordinary Shares of the Issuer may be represented by ADSs. Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
| June 17, 2026 Filed Jun 18, 2026 21:00 UTC |
Russell Angus C.Director
|
GrantShare Option (right to buy) · Derivative | 39,453 | $0.00 Strike: $15.00 | $0.00 |
DisclosureSEC source: 0001534002-26-000002 · form4-06182026_050614.xml · derivative · entry 1 Russell Angus C. · CIK 0001534002 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 39,453 Underlying: Ordinary Shares · 39,453 shares Expires 2036-06-16 F1 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's American Depositary Shares ("ADSs"). F2 · derivative.exercise_date: The shares vest in equal monthly installments over the 12 months following June 17, 2026, provided that the grant will in any case be fully vested on the date immediately prior to the date of the Issuer's 2027 annual shareholder meeting, F3 · derivative.underlying_shares: The Ordinary Shares of the Issuer may be represented by ADSs. Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
| June 17, 2026 Filed Jun 18, 2026 21:00 UTC |
Waldstreicher JoanneDirector
|
GrantShare Option (right to buy) · Derivative | 39,453 | $0.00 Strike: $15.00 | $0.00 |
DisclosureSEC source: 0001962413-26-000002 · form4-06182026_050609.xml · derivative · entry 1 Waldstreicher Joanne · CIK 0001962413 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 39,453 Underlying: Ordinary Shares · 39,453 shares Expires 2036-06-16 F1 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's American Depositary Shares ("ADSs"). F2 · derivative.exercise_date: The shares vest in equal monthly installments over the 12 months following June 17, 2026, provided that the grant will in any case be fully vested on the date immediately prior to the date of the Issuer's 2027 annual shareholder meeting, F3 · derivative.underlying_shares: The Ordinary Shares of the Issuer may be represented by ADSs. Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
| April 15, 2026 Filed Apr 23, 2026 20:21 UTC |
Lang MatthewCOO & GC
|
GrantShare option (right to buy) · Derivative | 223,776 | $0.00 Strike: $18.08 | $0.00 |
DisclosureSEC source: 0001712069-26-000007 · form4-04232026_080401.xml · derivative · entry 2 Lang Matthew · CIK 0001712069 · COO & GC 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 223,776 Underlying: Ordinary Shares · 223,776 shares Expires 2036-04-14 F3 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs. F4 · derivative.exercise_date: One-fourth of the shares vest on the first anniversary of April 15, 2026, and the remaining shares shall vest in thirty-six (36) equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date. F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
| April 15, 2026 Filed Apr 23, 2026 20:21 UTC |
Lang MatthewCOO & GC
|
GrantOrdinary Shares | 184,614 | $0.00 | $0.00 |
DisclosureSEC source: 0001712069-26-000007 · form4-04232026_080401.xml · nonDerivative · entry 1 Lang Matthew · CIK 0001712069 · COO & GC 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 184,614 F1 · security: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer. F2 · kind: Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer. The RSUs vest 1/4th annually on each anniversary of April 15, 2026, subject to Reporting Person's continued service on such dates. Read SEC document |
| April 14, 2026 Filed Apr 16, 2026 18:17 UTC |
FMR LLC10% owner · See Remark 1
|
SaleAmerican Depositary Shares · Derivative | 16,085 | $55.07 | $885,800.95 |
DisclosureSEC source: 0001193125-26-158649 · ownership.xml · derivative · entry 5 FMR LLC · CIK 0000315066 · 10% owner · See Remark 1 10b5-1 filing: No plan indicated Ownership: Indirect · F-Prime Capital Partners Life Sciences Fund VI LP Disclosed balance after: 32,171 Underlying: Ordinary Shares · 48,255 shares Expires not disclosed F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. F2 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $55.00 to $55.20. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information. F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Read SEC document |
| April 14, 2026 Filed Apr 16, 2026 18:17 UTC |
FMR LLC10% owner · See Remark 1
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SaleAmerican Depositary Shares · Derivative | 1,367 | $55.07 | $75,280.69 |
DisclosureSEC source: 0001193125-26-158649 · ownership.xml · derivative · entry 4 FMR LLC · CIK 0000315066 · 10% owner · See Remark 1 10b5-1 filing: No plan indicated Ownership: Indirect · F-Prime Capital Partners Life Sciences Advisors Fund VI LP Disclosed balance after: 2,736 Underlying: Ordinary Shares · 4,101 shares Expires not disclosed F1 · derivative.exercise_price: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. F2 · price: The price reported for this transaction is the weighted average price of multiple trades at prices ranging from $55.00 to $55.20. FMR LLC hereby undertakes to provide upon request by the Commission staff, the issuer, or a security holder of the issuer full information. F1 · derivative.exercise_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. F1 · derivative.expiration_date: Reported securities are represented by American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Read SEC document |
| March 19, 2026 Filed Mar 23, 2026 16:30 UTC |
Coll Crespo BlasCHIEF MEDICAL OFFICER
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GrantEmployee Stock Option (right to buy) · Derivative | 93,984 | $0.00 Strike: $16.82 | $0.00 |
DisclosureSEC source: 0002037144-26-000003 · form4-03232026_040308.xml · derivative · entry 2 Coll Crespo Blas · CIK 0002037144 · CHIEF MEDICAL OFFICER 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 93,984 Underlying: Ordinary Shares · 93,984 shares Expires 2036-03-18 F3 · derivative.exercise_price: The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs. F4 · derivative.exercise_date: 1/4th of the shares subject to the option shall vest March 1, 2027, and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date. F1 · derivative.underlying: The Ordinary Shares of the Issuer may be represented by American Depositary Shares ('ADSs"). Each ADS represents three Ordinary Shares of the Issuer. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.