GKOS

SEC source: 0001415889-23-002646 · form4-02152023_110224.xml · nonDerivative · entry 1

Navratil Tomas · CIK 0001920053 · CHIEF DEVELOPMENT OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 40,652

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 31,341 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-001599 · form4-01302023_100104.xml · nonDerivative · entry 2

Burns Thomas William · CIK 0001644557 · Director · CHAIRMAN & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 679,062

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 75,481 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-001599 · form4-01302023_100104.xml · nonDerivative · entry 1

Burns Thomas William · CIK 0001644557 · Director · CHAIRMAN & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 679,783

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

SEC source: 0001415889-23-001601 · form4-01302023_100129.xml · nonDerivative · entry 4

Navratil Tomas · CIK 0001920053 · CHIEF DEVELOPMENT OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,008

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 32,368 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-001601 · form4-01302023_100129.xml · nonDerivative · entry 3

Navratil Tomas · CIK 0001920053 · CHIEF DEVELOPMENT OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 41,364

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

SEC source: 0001415889-23-000993 · form4-01132023_100115.xml · nonDerivative · entry 1

Thurman Alex R. · CIK 0001920061 · SVP & CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,176

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 24,414 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000997 · form4-01132023_100118.xml · nonDerivative · entry 2

Gilliam Joseph E · CIK 0001705850 · PRESIDENT & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,374

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 78,097 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000997 · form4-01132023_100118.xml · nonDerivative · entry 1

Gilliam Joseph E · CIK 0001705850 · PRESIDENT & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 104,533

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 78,097 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000995 · form4-01132023_100143.xml · nonDerivative · entry 2

Burns Thomas William · CIK 0001644557 · Director · CHAIRMAN & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 681,585

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 82,775 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000995 · form4-01132023_100143.xml · nonDerivative · entry 1

Burns Thomas William · CIK 0001644557 · Director · CHAIRMAN & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 681,911

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 82,775 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-001601 · form4-01302023_100129.xml · nonDerivative · entry 2

Navratil Tomas · CIK 0001920053 · CHIEF DEVELOPMENT OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,249

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

SEC source: 0001415889-23-001601 · form4-01302023_100129.xml · nonDerivative · entry 1

Navratil Tomas · CIK 0001920053 · CHIEF DEVELOPMENT OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 42,638

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

SEC source: 0001415889-23-000434 · form4-01042023_110142.xml · nonDerivative · entry 1

Hoffmeister David F · CIK 0001305975 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,401

F1 · security: Represents a grant of restricted stock units received by the Reporting Person in lieu of annual director retainer fees pursuant to a stock-for-fees election under the Issuer's Director Compensation Policy. The units will vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 5,936 restricted stock units that have not vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000450 · form4-01042023_110107.xml · nonDerivative · entry 1

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,495

F1 · security: Represents a grant of restricted stock units received by the Reporting Person in lieu of annual director retainer fees pursuant to a stock-for-fees election under the Issuer's Director Compensation Policy. The units will vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 5,936 restricted stock units that have not vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000420 · form4-01042023_110145.xml · nonDerivative · entry 1

WEISNER AIMEE S · CIK 0001227308 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,278

F1 · security: Represents a grant of restricted stock units received by the Reporting Person in lieu of annual director retainer fees pursuant to a stock-for-fees election under the Issuer's Director Compensation Policy. The units will vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 10,753 restricted stock units that have not vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000469 · form4-01052023_010148.xml · nonDerivative · entry 1

Torres Denice · CIK 0001820278 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,301

F1 · security: Represents a grant of restricted stock units received by the Reporting Person in lieu of annual director retainer fees pursuant to a stock-for-fees election under the Issuer's Director Compensation Policy. The units will vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 7,990 restricted stock units that have not vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000444 · form4-01042023_110104.xml · nonDerivative · entry 1

WEN LEANA · CIK 0001847598 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,301

F1 · security: Represents a grant of restricted stock units received by the Reporting Person in lieu of annual director retainer fees pursuant to a stock-for-fees election under the Issuer's Director Compensation Policy. The units will vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Consists of restricted stock units that have not vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000440 · form4-01042023_110127.xml · nonDerivative · entry 1

WEN LEANA · CIK 0001847598 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,301

F1 · security: Represents a grant of restricted stock units received by the Reporting Person in lieu of annual director retainer fees pursuant to a stock-for-fees election under the Issuer's Director Compensation Policy. The units will vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 7,990 restricted stock units that have not vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000400 · form4-01042023_110138.xml · nonDerivative · entry 1

Stapley Marc · CIK 0001539796 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,086

F1 · security: Represents a grant of restricted stock units received by the Reporting Person in lieu of annual director retainer fees pursuant to a stock-for-fees election under the Issuer's Director Compensation Policy. The units will vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 9,830 restricted stock units that have not vested or been delivered to the Reporting Person.

SEC source: 0001415889-23-000386 · form4-01042023_100145.xml · nonDerivative · entry 1

Foley Mark J · CIK 0001529196 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,550

F1 · security: Represents a grant of restricted stock units received by the Reporting Person in lieu of annual director retainer fees pursuant to a stock-for-fees election under the Issuer's Director Compensation Policy. The units will vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 7,312 restricted stock units that have not vested or been delivered to the Reporting Person.

SEC source: 0001415889-22-012788 · form4-12202022_121255.xml · derivative · entry 1

Thurman Alex R. · CIK 0001920061 · SVP & CHIEF FINANCIAL OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,148

Underlying: Common Stock · 9,148 shares

Expires 2032-03-24

F1 · shares: Represents a portion of an option to purchase shares of common stock previously granted by the Issuer on March 24, 2022, the vesting of which was subject to the Issuer's achievement of certain pre-determined operational targets over a multi-year performance period. The Compensation, Nominating and Governance Committee of the Issuer's Board of Directors determined on December 15, 2022 that certain of the operational targets had been achieved. The number of shares of common stock subject to the stock option as reported herein consists of the portion of the award that was earned based upon the achievement of the operational targets.

F2 · derivative.exercise_date: 70% of the portion of the option reported herein will vest and become exercisable in January 2023 and the remaining 30% will vest and become exercisable in March 2023.

SEC source: 0001415889-22-012790 · form4-12202022_121207.xml · derivative · entry 1

Gilliam Joseph E · CIK 0001705850 · PRESIDENT & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 18,295

Underlying: Common Stock · 18,295 shares

Expires 2032-03-24

F1 · shares: Represents a portion of an option to purchase shares of common stock previously granted by the Issuer on March 24, 2022, the vesting of which was subject to the Issuer's achievement of certain pre-determined operational targets over a multi-year performance period. The Compensation, Nominating and Governance Committee of the Issuer's Board of Directors determined on December 15, 2022 that certain of the operational targets had been achieved. The number of shares of common stock subject to the stock option as reported herein consists of the portion of the award that was earned based upon the achievement of the operational targets.

F2 · derivative.exercise_date: 70% of the portion of the option reported herein will vest and become exercisable in January 2023, and the remaining 30% will vest and become exercisable in March 2023.

SEC source: 0001415889-22-012786 · form4-12202022_121244.xml · derivative · entry 2

Burns Thomas William · CIK 0001644557 · Director · CHAIRMAN & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,039

Underlying: Common Stock · 21,039 shares

Expires 2032-03-24

F3 · shares: Represents a portion of an option to purchase shares of common stock previously granted by the Issuer on March 24, 2022, the vesting of which was subject to the Issuer's achievement of certain pre-determined operational targets over a multi-year performance period. The Compensation Committee determined on December 15, 2022 that certain of the operational targets had been achieved. The number of shares of common stock subject to the stock option as reported herein consists of the portion of the award that was earned based upon the achievement of the operational targets.

F4 · derivative.exercise_date: 70% of the portion of the option reported herein will vest and become exercisable in January 2023, and the remaining 30% will vest and become exercisable in March 2023.

SEC source: 0001415889-22-012786 · form4-12202022_121244.xml · nonDerivative · entry 1

Burns Thomas William · CIK 0001644557 · Director · CHAIRMAN & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 684,705

F1 · shares: Represents shares of common stock underlying a portion of an award of restricted stock units previously granted by the Issuer on March 24, 2022, the vesting of which was subject to the Issuer's achievement of certain pre-determined operational targets over a multi-year performance period. The Compensation, Nominating and Governance Committee of the Issuer's Board of Directors (the "Compensation Committee") determined on December 15, 2022 that certain of the operational targets had been achieved. The number of shares of common stock reported herein consists of the portion of the award that was earned based upon the achievement of the operational targets. 70% of the number of shares of common stock reported herein will vest and be delivered in January 2023, and the remaining 30% will vest and be delivered in March 2023.

F2 · balance_after: Includes 91,279 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-22-012792 · form4-12202022_121229.xml · nonDerivative · entry 1

Navratil Tomas · CIK 0001920053 · CHIEF DEVELOPMENT OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 43,937

F1 · shares: Represents shares of common stock underlying a portion of an award of restricted stock units previously granted by the Issuer on March 24, 2022, the vesting of which was subject to the Issuer's achievement of certain pre-determined operational targets over a multi-year performance period. The Compensation, Nominating and Governance Committee of the Issuer's Board of Directors determined on December 15, 2022 that certain of the operational targets had been achieved. The number of shares of common stock reported herein consists of the portion of the award that was earned based upon the achievement of the operational targets. 70% of the number of shares of common stock reported herein will vest and be delivered in January 2023 and the remaining 30% will vest and be delivered in March 2023.

F2 · balance_after: Includes 40,131 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-22-012083 · form4-12062022_121225.xml · nonDerivative · entry 2

Gilliam Joseph E · CIK 0001705850 · PRESIDENT & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 105,328

F3 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer on March 18, 2021.

F4 · balance_after: Includes 80,428 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-22-012081 · form4-12062022_121213.xml · nonDerivative · entry 2

Burns Thomas William · CIK 0001644557 · Director · CHAIRMAN & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 674,285

F3 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer on March 18, 2021.

F4 · balance_after: Includes 80,859 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-22-012085 · form4-12062022_121214.xml · nonDerivative · entry 2

Navratil Tomas · CIK 0001920053 · CHIEF DEVELOPMENT OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 38,802

F3 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer on March 18, 2021.

F4 · balance_after: Includes 34,996 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-22-012083 · form4-12062022_121225.xml · nonDerivative · entry 1

Gilliam Joseph E · CIK 0001705850 · PRESIDENT & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 106,006

F1 · shares: Represents shares of common stock underlying a portion of an award of restricted stock units previously granted by the Issuer on March 18, 2021, the vesting of which was subject to the Issuer's achievement of certain pre-determined operational targets over a multi-year performance period. The Compensation Committee determined on September 15, 2022 that one of the operational targets had been achieved. The Reporting Person elected to receive this performance grant in the form of restricted stock units. The number of shares reported herein consists of the portion of the award that was deemed earned based upon the achievement of the operational target. 50% of the number of shares of common stock reported herein vested and was delivered on November 25, 2022 and the remaining 50% will vest and be delivered on August 2, 2023.

F2 · balance_after: Includes 82,371 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-22-012081 · form4-12062022_121213.xml · nonDerivative · entry 1

Burns Thomas William · CIK 0001644557 · Director · CHAIRMAN & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 678,108

F1 · shares: Represents shares of common stock underlying a portion of an award of restricted stock units previously granted by the Issuer on March 18, 2021, the vesting of which was subject to the Issuer's achievement of certain pre-determined operational targets over a multi-year performance period. The Compensation Committee determined on September 15, 2022 that one of the operational targets had been achieved. The Reporting Person elected to receive this performance grant in the form of restricted stock units. The number of shares reported herein consists of the portion of the award that was deemed earned based upon the achievement of the operational target. 50% of the number of shares of common stock reported herein vested and was delivered on November 25, 2022 and the remaining 50% will vest and be delivered on August 2, 2023.

F2 · balance_after: Includes 88,568 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001415889-22-012085 · form4-12062022_121214.xml · nonDerivative · entry 1

Navratil Tomas · CIK 0001920053 · CHIEF DEVELOPMENT OFFICER

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 39,140

F1 · shares: Represents shares of common stock underlying a portion of an award of restricted stock units previously granted by the Issuer on March 18, 2021, the vesting of which was subject to the Issuer's achievement of certain pre-determined operational targets over a multi-year performance period. The Compensation Committee determined on September 15, 2022 that one of the operational targets had been achieved. The Reporting Person elected to receive this performance grant in the form of restricted stock units. The number of shares reported herein consists of the portion of the award that was deemed earned based upon the achievement of the operational target. 50% of the number of shares of common stock reported herein vested and was delivered on November 25, 2022 and the remaining 50% will vest and be delivered on August 2, 2023.

F2 · balance_after: Includes 35,971 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0000899243-22-029268 · doc4.xml · nonDerivative · entry 2

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By InterWest Venture Management Company

Disclosed balance after: 16,347

F1 · kind: The Reporting Person transferred these shares to InterWest Venture Management Company ("IVMC") for no consideration, pursuant to an agreement between the Reporting Person and InterWest Partners X, LP ("IP10") relating to compensation received in connection with his service as director of the Issuer.

F2 · ownership.nature: Consists of shares owned by IVMC. The Reporting Person is an officer, director and shareholder of IVMC and has sole voting and investment control over the shares held by IVMC.

SEC source: 0000899243-22-029268 · doc4.xml · nonDerivative · entry 1

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,923

F1 · kind: The Reporting Person transferred these shares to InterWest Venture Management Company ("IVMC") for no consideration, pursuant to an agreement between the Reporting Person and InterWest Partners X, LP ("IP10") relating to compensation received in connection with his service as director of the Issuer.

F3 · balance_after: Includes 4,364 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0000899243-22-028000 · doc4.xml · nonDerivative · entry 5

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By InterWest Partners IX, LP

Disclosed balance after: 0

F4 · price: The price represents the weighted-average price of the shares sold in multiple transactions ranging from $52.77 to $53.165 per share, inclusive. The Reporting Person undertakes to provide the Issuer, a security holder of the Issuer, or the Staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

F5 · ownership.nature: Consists of shares owned by InterWest Partners IX, LP ("IP9"). The Reporting Person is a Managing Director of InterWest Management Partners IX, LLC, the general partner of IP9. The Reporting Person has shared voting and investment control over shares owned by IP9, and disclaims beneficial ownership of those securities, except to the extent of his pecuniary interest therein.

SEC source: 0000899243-22-028000 · doc4.xml · nonDerivative · entry 4

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,305

F2 · kind: Represents pro rata in-kind distribution by IMP10 without consideration to its members in accordance with the terms of the InterWest Management Partners X, LLC Operating Agreement. Includes 19,045 shares distributed to the Reporting Person.

F7 · balance_after: Includes 6,746 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0000899243-22-028000 · doc4.xml · nonDerivative · entry 3

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · InterWest Management Partners X, LLC

Disclosed balance after: 0

F2 · kind: Represents pro rata in-kind distribution by IMP10 without consideration to its members in accordance with the terms of the InterWest Management Partners X, LLC Operating Agreement. Includes 19,045 shares distributed to the Reporting Person.

F3 · ownership.nature: The shares are owned by IP10. The general partner of IP10 is IMP10. The Reporting Person has shared voting and investment control over shares owned by IP10, and disclaims beneficial ownership of those securities, except to the extent of his pecuniary interest therein.

SEC source: 0000899243-22-028000 · doc4.xml · nonDerivative · entry 2

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · InterWest Management Partners X, LLC

Disclosed balance after: 83,955

F1 · kind: Represents pro rata in-kind distribution by InterWest Partners X, LP ("IP10") without consideration to its limited and general partners in accordance with the terms of the InterWest Partners X, LP Limited Partnership Agreement. Includes 83,955 shares distributed to InterWest Management Partners X, LLC ("IMP10") its general partner.

F3 · ownership.nature: The shares are owned by IP10. The general partner of IP10 is IMP10. The Reporting Person has shared voting and investment control over shares owned by IP10, and disclaims beneficial ownership of those securities, except to the extent of his pecuniary interest therein.

SEC source: 0000899243-22-028000 · doc4.xml · nonDerivative · entry 1

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · InterWest Partners X, LP

Disclosed balance after: 0

F1 · kind: Represents pro rata in-kind distribution by InterWest Partners X, LP ("IP10") without consideration to its limited and general partners in accordance with the terms of the InterWest Partners X, LP Limited Partnership Agreement. Includes 83,955 shares distributed to InterWest Management Partners X, LLC ("IMP10") its general partner.

F3 · ownership.nature: The shares are owned by IP10. The general partner of IP10 is IMP10. The Reporting Person has shared voting and investment control over shares owned by IP10, and disclaims beneficial ownership of those securities, except to the extent of his pecuniary interest therein.

SEC source: 0001104659-22-068665 · tm2217841-3_4seq1.xml · nonDerivative · entry 1

Hoffmeister David F · CIK 0001305975 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,829

F1 · security: Represents a grant of restricted stock units that vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 8,201 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001104659-22-068662 · tm2217841-1_4seq1.xml · nonDerivative · entry 1

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,260

F1 · security: Represents a grant of restricted stock units that vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 6,746 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001104659-22-068669 · tm2217841-6_4seq1.xml · nonDerivative · entry 1

WEISNER AIMEE S · CIK 0001227308 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 22,706

F1 · security: Represents a grant of restricted stock units that vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 8,201 restricted stock units that have not yet vested or been delivered to the Reporting Person, and 980 restricted stock units that have vested but have not yet been delivered to the Reporting Person based upon the Reporting Person's election to defer delivery.

SEC source: 0001104659-22-068670 · tm2217841-7_4seq1.xml · nonDerivative · entry 1

WEN LEANA · CIK 0001847598 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,729

F1 · security: Represents a grant of restricted stock units that vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Consists of 10,254 restricted stock units that have not yet vested or been delivered to the Reporting Person, and 1,475 restricted stock units that have vested but have not yet been delivered to the Reporting Person based upon the Reporting Person's election to defer delivery.

SEC source: 0001104659-22-068667 · tm2217841-5_4seq1.xml · nonDerivative · entry 1

Foley Mark J · CIK 0001529196 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,602

F1 · security: Represents a grant of restricted stock units that vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 9,232 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001104659-22-068666 · tm2217841-4_4seq1.xml · nonDerivative · entry 1

Torres Denice · CIK 0001820278 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,729

F1 · security: Represents a grant of restricted stock units that vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 10,255 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001104659-22-068664 · tm2217841-2_4seq1.xml · nonDerivative · entry 1

Stapley Marc · CIK 0001539796 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 26,186

F1 · security: Represents a grant of restricted stock units that vest in full on the one-year anniversary of the grant date and are payable in an equivalent number of shares of the Issuer's common stock.

F2 · balance_after: Includes 8,504 restricted stock units that have not yet vested or been delivered to the Reporting Person, and 1,184 restricted stock units that have vested but have not yet been delivered to the Reporting Person based upon the Reporting Person's election to defer delivery.

SEC source: 0000899243-22-018663 · doc4.xml · nonDerivative · entry 2

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Indirect · By InterWest Venture Management Co.

Disclosed balance after: 13,965

F1 · kind: The Reporting Person transferred these shares to InterWest Venture Management Company ("IVMC") for no consideration, pursuant to an agreement between the Reporting Person and InterWest Partners X, LP ("IP10") relating to compensation received in connection with his service as director of the Issuer.

F2 · ownership.nature: The shares are owned by IVMC. The Reporting Person is an officer, director and the sole shareholder of IVMC and has sole voting and investment control over the shares held by IVMC.

SEC source: 0000899243-22-018663 · doc4.xml · nonDerivative · entry 1

Kliman Gilbert H · CIK 0001293171 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,896

F1 · kind: The Reporting Person transferred these shares to InterWest Venture Management Company ("IVMC") for no consideration, pursuant to an agreement between the Reporting Person and InterWest Partners X, LP ("IP10") relating to compensation received in connection with his service as director of the Issuer.

F5 · balance_after: Includes 2,382 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001104659-22-048497 · tm2213003-4_4seq1.xml · nonDerivative · entry 1

Gilliam Joseph E · CIK 0001705850 · President & COO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,614

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 75,979 restricted stock units that have not yet vested or been delivered to the Reporting Person.

SEC source: 0001104659-22-048494 · tm2213003-2_4seq1.xml · nonDerivative · entry 1

Burns Thomas William · CIK 0001644557 · Director · Chief Executive Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 662,691

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 73,151 RSUs that have not yet vested and been delivered to the Reporting Person.

SEC source: 0001104659-22-048495 · tm2213003-3_4seq1.xml · nonDerivative · entry 1

Navratil Tomas · CIK 0001920053 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,191

F1 · shares: Consists of shares withheld by the Issuer with respect to tax withholding obligations of the Reporting Person upon vesting and delivery of shares of common stock underlying restricted stock units previously granted by the Issuer.

F2 · balance_after: Includes 34,022 restricted stock units that have not yet vested or been delivered to the Reporting Person.