FATE

SEC source: 0001209191-21-028259 · doc4.xml · nonDerivative · entry 1

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 423,793

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

SEC source: 0001209191-21-027545 · doc4.xml · nonDerivative · entry 3

Chu Yu-Waye · CIK 0001854586 · Senior VP Clinical Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 64,800

F1 · shares: Required number of shares sold by the reporting person to cover tax withholding obligations in connection with the vesting of 7,500 shares of Common Stock underlying RSUs granted to the reporting person on April 15, 2019. This sale was made pursuant to an irrevocable election by the reporting person to satisfy tax withholding obligations through a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F4 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $83.635 to $84.61 per share. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001209191-21-027545 · doc4.xml · nonDerivative · entry 2

Chu Yu-Waye · CIK 0001854586 · Senior VP Clinical Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 66,300

F1 · shares: Required number of shares sold by the reporting person to cover tax withholding obligations in connection with the vesting of 7,500 shares of Common Stock underlying RSUs granted to the reporting person on April 15, 2019. This sale was made pursuant to an irrevocable election by the reporting person to satisfy tax withholding obligations through a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F3 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $82.6175 to $83.23 per share. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0001209191-21-027545 · doc4.xml · nonDerivative · entry 1

Chu Yu-Waye · CIK 0001854586 · Senior VP Clinical Development

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 67,200

F1 · shares: Required number of shares sold by the reporting person to cover tax withholding obligations in connection with the vesting of 7,500 shares of Common Stock underlying RSUs granted to the reporting person on April 15, 2019. This sale was made pursuant to an irrevocable election by the reporting person to satisfy tax withholding obligations through a "sell to cover" transaction and does not represent a discretionary trade by the reporting person.

F2 · price: The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $81.395 to $82.205 per share. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000899243-21-014635 · doc4.xml · derivative · entry 12

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 10,458

Underlying: Common Stock · 1,851 shares

Expires 2023-08-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F11 · derivative.exercise_date: 1/2 of the shares subject to this option vested in 48 equal monthly installments beginning on November 4, 2013. The remaining 1/2 of the shares are divided into five equal parts, and 1/5 of such remaining shares vested in 24 equal monthly installments following the Issuer's achievement of one of the five specified performance based milestones.

SEC source: 0000899243-21-014635 · doc4.xml · derivative · entry 11

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 28,149 shares

Expires 2026-01-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F10 · derivative.exercise_date: The shares subject to this option vested in 48 equal monthly installments beginning on February 8, 2016.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 10

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 108,048

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F9 · price: Represents the weighted average sale price of the shares sold ranging from $87.36 to $87.53 per share.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 9

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 108,448

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F8 · price: Represents the weighted average sale price of the shares sold ranging from $86.34 to $87.32 per share.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 8

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 113,747

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F7 · price: Represents the weighted average sale price of the shares sold ranging from $85.34 to $86.33 per share.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 7

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 118,582

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F6 · price: Represents the weighted average sale price of the shares sold ranging from $84.08 to $84.97 per share.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 6

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,782

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F5 · price: Represents the weighted average sale price of the shares sold ranging from $83.08 to $84.06 per share.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 5

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 124,272

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F4 · price: Represents the weighted average sale price of the shares sold ranging from $82.08 to $83.07 per share.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 4

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 128,828

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F3 · price: Represents the weighted average sale price of the shares sold ranging from $81.02 to $81.85 per share.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 3

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 137,048

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F2 · price: Represents the weighted average sale price of the shares sold ranging from $80.02 to $81.00 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price within the ranges set forth in footnotes 2 through 9.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 2

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 138,048

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

SEC source: 0000899243-21-014635 · doc4.xml · nonDerivative · entry 1

TAHL CINDY · CIK 0001655472 · See Remarks

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 136,197

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

SEC source: 0000899243-21-011920 · doc4.xml · derivative · entry 7

Valamehr Bahram · CIK 0001748177 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,156

Underlying: Common Stock · 25,000 shares

Expires 2026-01-07

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 sales plan adopted by the Reporting Person on June 9, 2020.

F7 · derivative.exercise_date: This option is fully vested.

SEC source: 0000899243-21-011920 · doc4.xml · nonDerivative · entry 6

Valamehr Bahram · CIK 0001748177 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 95,740

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 sales plan adopted by the Reporting Person on June 9, 2020.

F6 · price: Represents the weighted average sale price of the shares sold from $94.40 to $94.90 per share.

SEC source: 0000899243-21-011920 · doc4.xml · nonDerivative · entry 5

Valamehr Bahram · CIK 0001748177 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 96,758

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 sales plan adopted by the Reporting Person on June 9, 2020.

F5 · price: Represents the weighted average sale price of the shares sold from $93.31 to $94.29 per share.

SEC source: 0000899243-21-011920 · doc4.xml · nonDerivative · entry 4

Valamehr Bahram · CIK 0001748177 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 99,963

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 sales plan adopted by the Reporting Person on June 9, 2020.

F4 · price: Represents the weighted average sale price of the shares sold from $92.31 to $93.27 per share.

SEC source: 0000899243-21-011920 · doc4.xml · nonDerivative · entry 3

Valamehr Bahram · CIK 0001748177 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 108,367

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 sales plan adopted by the Reporting Person on June 9, 2020.

F3 · price: Represents the weighted average sale price of the shares sold from $91.30 to $92.29 per share.

SEC source: 0000899243-21-011920 · doc4.xml · nonDerivative · entry 2

Valamehr Bahram · CIK 0001748177 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,783

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 sales plan adopted by the Reporting Person on June 9, 2020.

F2 · price: Represents the weighted average sale price of the shares sold from $90.30 to $91.29 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer or a security holder of he Issuer, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes 2 through 6.

SEC source: 0000899243-21-011920 · doc4.xml · nonDerivative · entry 1

Valamehr Bahram · CIK 0001748177 · Chief Development Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 120,740

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 sales plan adopted by the Reporting Person on June 9, 2020.

F1 · price: This transaction was effected pursuant to a Rule 10b5-1 sales plan adopted by the Reporting Person on June 9, 2020.

SEC source: 0001209191-21-018932 · doc4.xml · nonDerivative · entry 8

Shoemaker Daniel D · CIK 0001586892 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,020

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 12, 2020.

SEC source: 0001209191-21-018932 · doc4.xml · nonDerivative · entry 7

Shoemaker Daniel D · CIK 0001586892 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 73,820

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 12, 2020.

F8 · price: Represents the weighted average sale price of the shares sold ranging from $84.99 to $85.81 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-018932 · doc4.xml · nonDerivative · entry 6

Shoemaker Daniel D · CIK 0001586892 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 76,720

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 12, 2020.

F7 · price: Represents the weighted average sale price of the shares sold ranging from $83.775 to $84.76 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-018932 · doc4.xml · nonDerivative · entry 5

Shoemaker Daniel D · CIK 0001586892 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 79,448

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 12, 2020.

F6 · price: Represents the weighted average sale price of the shares sold ranging from $82.74 to $83.68 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-018932 · doc4.xml · nonDerivative · entry 4

Shoemaker Daniel D · CIK 0001586892 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,928

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 12, 2020.

F5 · price: Represents the weighted average sale price of the shares sold ranging from $81.19 to $82.15 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-018932 · doc4.xml · nonDerivative · entry 3

Shoemaker Daniel D · CIK 0001586892 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 84,921

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 12, 2020.

F4 · price: Represents the weighted average sale price of the shares sold ranging from $80.12 to $81.09 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-018932 · doc4.xml · nonDerivative · entry 2

Shoemaker Daniel D · CIK 0001586892 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 90,095

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 12, 2020.

F3 · price: Represents the weighted average sale price of the shares sold ranging from $79.09 to $80.08 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-018932 · doc4.xml · nonDerivative · entry 1

Shoemaker Daniel D · CIK 0001586892 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 94,722

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 12, 2020.

F2 · price: Represents the weighted average sale price of the shares sold ranging from $78.08 to $79.02 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-012326 · doc4.xml · derivative · entry 7

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,846

Underlying: Common Stock · 20,000 shares

Expires 2024-01-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F8 · price: Not applicable.

F7 · derivative.exercise_date: This option is fully vested.

SEC source: 0001209191-21-012326 · doc4.xml · nonDerivative · entry 6

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 393,793

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F6 · price: Represents the weighted average sale price of the shares sold ranging from $102.86 to $103.66 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-012326 · doc4.xml · nonDerivative · entry 5

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 399,340

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F5 · price: Represents the weighted average sale price of the shares sold ranging from $101.85 to $102.84 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-012326 · doc4.xml · nonDerivative · entry 4

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 407,942

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F4 · price: Represents the weighted average sale price of the shares sold ranging from $100.83 to $101.82 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-012326 · doc4.xml · nonDerivative · entry 3

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 410,544

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F3 · price: Represents the weighted average sale price of the shares sold ranging from $99.825 to $100.81 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-012326 · doc4.xml · nonDerivative · entry 2

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 412,392

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F2 · price: Represents the weighted average sale price of the shares sold ranging from $98.65 to $99.645 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-012326 · doc4.xml · nonDerivative · entry 1

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 413,793

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

SEC source: 0001209191-21-004957 · doc4.xml · derivative · entry 20

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,846

Underlying: Common Stock · 20,000 shares

Expires 2024-01-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F16 · price: Not applicable.

F17 · derivative.exercise_date: This option is fully vested.

SEC source: 0001209191-21-004957 · doc4.xml · derivative · entry 19

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 170,000

Underlying: Common Stock · 10,000 shares

Expires 2027-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F16 · price: Not applicable.

F17 · derivative.exercise_date: This option is fully vested.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 16

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 393,793

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F14 · price: Represents the weighted average sale price of the shares sold ranging from $99.81 to $100.45 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 15

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 396,868

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F13 · price: Represents the weighted average sale price of the shares sold ranging from $98.80 to $99.76 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 14

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 403,388

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F12 · price: Represents the weighted average sale price of the shares sold ranging from $97.80 to $98.79 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 13

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 411,026

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F11 · price: Represents the weighted average sale price of the shares sold ranging from $96.77 to $97.75 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 12

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 423,793

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 11

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 403,793

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

SEC source: 0001209191-21-004957 · doc4.xml · derivative · entry 18

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,000

Underlying: Common Stock · 30,000 shares

Expires 2027-01-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F16 · price: Not applicable.

F17 · derivative.exercise_date: This option is fully vested.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 10

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 393,793

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F10 · price: Represents the weighted average sale price of the shares sold ranging from $106.84 to $107.07 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 9

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 393,993

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F9 · price: Represents the weighted average sale price of the shares sold ranging from $105.75 to $106.47 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.

SEC source: 0001209191-21-004957 · doc4.xml · nonDerivative · entry 8

Wolchko J Scott · CIK 0001586893 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 394,638

F2 · kind: This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2020.

F8 · price: Represents the weighted average sale price of the shares sold ranging from $104.75 to $105.73 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price.