ENGN

SEC source: 0001552781-26-000501 · ownership.xml · nonDerivative · entry 1

Grossman William · CIK 0001730229 · Director · Interim Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,102

SEC source: 0000929638-26-002257 · form4.xml · derivative · entry 1

Joustra Wouter · CIK 0001897813 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Shares · 31,000 shares

Expires 2036-06-16

F1 · derivative.exercise_date: This option vests fully on the earlier of (i) the first anniversary of the vesting commencement date, which was June 9, 2026 or (ii) the registrant's 2027 annual meeting of shareholders.

SEC source: 0000929638-26-002258 · form4.xml · derivative · entry 1

Heffernan Michael Thomas · CIK 0001448914 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Shares · 31,000 shares

Expires 2036-06-16

F1 · derivative.exercise_date: This option vests fully on the earlier of (i) the first anniversary of the vesting commencement date, which was June 9, 2026 or (ii) the registrant's 2027 annual meeting of shareholders.

SEC source: 0000929638-26-002263 · form4.xml · derivative · entry 1

Astley-Sparke Philip · CIK 0001376491 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Shares · 31,000 shares

Expires 2036-06-16

F1 · derivative.exercise_date: This option vests fully on the earlier of (i) the first anniversary of the vesting commencement date, which was June 9, 2026 or (ii) the registrant's 2027 annual meeting of shareholders.

SEC source: 0000929638-26-002256 · form4.xml · derivative · entry 1

Zoth Lota S. · CIK 0001278219 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Shares · 31,000 shares

Expires 2036-06-16

F1 · derivative.exercise_date: This option vests fully on the earlier of (i) the first anniversary of the vesting commencement date, which was June 9, 2026 or (ii) the registrant's 2027 annual meeting of shareholders.

SEC source: 0000929638-26-002259 · form4.xml · derivative · entry 1

HASTINGS PAUL J · CIK 0001309702 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Shares · 31,000 shares

Expires 2036-06-16

F1 · derivative.exercise_date: This option vests fully on the earlier of (i) the first anniversary of the vesting commencement date, which was June 9, 2026 or (ii) the registrant's 2027 annual meeting of shareholders.

SEC source: 0000929638-26-002261 · form4.xml · derivative · entry 1

Glickman Richard M · CIK 0001352637 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Shares · 31,000 shares

Expires 2036-06-16

F1 · derivative.exercise_date: This option vests fully on the earlier of (i) the first anniversary of the vesting commencement date, which was June 9, 2026 or (ii) the registrant's 2027 annual meeting of shareholders.

SEC source: 0000929638-26-002262 · form4.xml · derivative · entry 1

BRUNK GERALD A · CIK 0001380226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Shares · 31,000 shares

Expires 2036-06-16

F1 · derivative.exercise_date: This option vests fully on the earlier of (i) the first anniversary of the vesting commencement date, which was June 9, 2026 or (ii) the registrant's 2027 annual meeting of shareholders.

SEC source: 0000929638-26-002260 · form4.xml · derivative · entry 2

Grossman William · CIK 0001730229 · Director · Interim Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 200,000

Underlying: Common Shares · 200,000 shares

Expires 2036-06-16

F2 · derivative.exercise_date: This option vests monthly in substantially equal amounts on the 12th day of each month for 12 consecutive months, subject to the reporting person's continued service as Interim Chief Medical Officer at the time of each vesting. These options were granted to the reporting person in connection with his appointment as the Interim Chief Medical Officer of the Company.

SEC source: 0000929638-26-002260 · form4.xml · derivative · entry 1

Grossman William · CIK 0001730229 · Director · Interim Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,000

Underlying: Common Shares · 31,000 shares

Expires 2036-06-16

F1 · derivative.exercise_date: This option vests fully on the earlier of (i) the first anniversary of the vesting commencement date, which was June 9, 2026 or (ii) the registrant's 2027 annual meeting of shareholders. These options were granted to the reporting person on June 16, 2026 for his service as a non-executive director, consistent with annual grants made to other non-executive directors of the board.

SEC source: 0000929638-26-000478 · form4.xml · derivative · entry 1

Boyd Matthew Ross · CIK 0002077001 · Chief Regulatory Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 195,000

Underlying: Common Shares · 195,000 shares

Expires 2036-01-30

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-26-000479 · form4.xml · derivative · entry 1

Connolly Joan · CIK 0002041481 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 195,000

Underlying: Common Shares · 195,000 shares

Expires 2036-01-30

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-26-000481 · form4.xml · derivative · entry 1

Daws D. Ryan · CIK 0001598602 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 220,000

Underlying: Common Shares · 220,000 shares

Expires 2036-01-30

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-26-000480 · form4.xml · derivative · entry 1

Cooper Ronald Harold Wilfred · CIK 0001676880 · Director · CEO & President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 801,000

Underlying: Common Shares · 801,000 shares

Expires 2036-01-30

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-26-000477 · form4.xml · derivative · entry 1

Buck Jill · CIK 0001780426 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 195,000

Underlying: Common Shares · 195,000 shares

Expires 2036-01-30

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-26-000483 · form4.xml · derivative · entry 1

Giguere Lee · CIK 0001796465 · Chief Legal Ofc. and Corp Secy

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 195,000

Underlying: Common Shares · 195,000 shares

Expires 2036-01-30

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-26-000484 · form4.xml · derivative · entry 1

CHEUNG ANTHONY TZEYEW · CIK 0001998684 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 195,000

Underlying: Common Shares · 195,000 shares

Expires 2036-01-30

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-26-000482 · form4.xml · derivative · entry 1

Nichols Alexander Julian · CIK 0001998744 · Chief Strategy & Ops. Ofc

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 195,000

Underlying: Common Shares · 195,000 shares

Expires 2036-01-30

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-25-003710 · form4.xml · derivative · entry 1

Sweiti Hussein · CIK 0002088436 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 600,000

Underlying: Common Shares · 600,000 shares

Expires 2035-09-30

F1 · derivative.exercise_date: Non-qualified stock option grant awarded as an inducement award outside of the Amended and Restated enGene Holdings Inc. 2023 Incentive Equity Plan in accordance with NASDAQ Listing Rule 5635(c)(4). This option vests at 25% on September 29, 2026, which is the first anniversary of the employment commencement date, with the remaining portion to vest monthly over the remaining three years, subject to the reporting person's continued service.

SEC source: 0000929638-25-002557 · form4.xml · derivative · entry 1

Heffernan Michael Thomas · CIK 0001448914 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Shares · 45,000 shares

Expires 2035-07-08

F1 · derivative.exercise_date: This option vests at 1/3 on each of the first, second and third anniversaries of Mr. Heffernan's date of appointment to the Board, which was July 8, 2025.

SEC source: 0000929638-25-002558 · form4.xml · derivative · entry 1

Astley-Sparke Philip · CIK 0001376491 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Shares · 45,000 shares

Expires 2035-07-08

F1 · derivative.exercise_date: This option vests at 1/3 on each of the first, second and third anniversaries of Mr. Astley-Sparke's date of appointment to the Board, which was July 8, 2025.

SEC source: 0000929638-25-002556 · form4.xml · derivative · entry 1

Grossman William · CIK 0001730229 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 45,000

Underlying: Common Shares · 45,000 shares

Expires 2035-07-08

F1 · derivative.exercise_date: This option vests at 1/3 on each of the first, second and third anniversaries of Dr. Grossman's date of appointment to the Board, which was July 8, 2025.

SEC source: 0000929638-25-002554 · form4.xml · derivative · entry 1

Buck Jill · CIK 0001780426 · Chief Development Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Shares · 100,000 shares

Expires 2035-07-08

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-25-002586 · form4.xml · derivative · entry 1

Boyd Matthew Ross · CIK 0002077001 · Chief Regulatory Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Shares · 100,000 shares

Expires 2035-07-08

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-25-002251 · form4.xml · derivative · entry 1

Joustra Wouter · CIK 0001897813 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Shares · 22,500 shares

Expires 2035-06-16

F1 · derivative.exercise_date: This option fully vests on the earlier of (i) the first anniversary of the date vesting commenced, which was June 10, 2025; or (ii) the 2026 Annual Meeting of Shareholders.

SEC source: 0000929638-25-002247 · form4.xml · derivative · entry 1

Bos Jasper · CIK 0001897789 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Shares · 22,500 shares

Expires 2035-06-16

F1 · derivative.exercise_date: This option fully vests on the earlier of (i) the first anniversary of the date vesting commenced, which was June 10, 2025; or (ii) the 2026 Annual Meeting of Shareholders.

SEC source: 0000929638-25-002253 · form4.xml · derivative · entry 1

Zoth Lota S. · CIK 0001278219 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Shares · 22,500 shares

Expires 2035-06-16

F1 · derivative.exercise_date: This option fully vests on the earlier of (i) the first anniversary of the date vesting commenced, which was June 10, 2025; or (ii) the 2026 Annual Meeting of Shareholders.

SEC source: 0000929638-25-002250 · form4.xml · derivative · entry 1

HASTINGS PAUL J · CIK 0001309702 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Shares · 22,500 shares

Expires 2035-06-16

F1 · derivative.exercise_date: This option fully vests on the earlier of (i) the first anniversary of the date vesting commenced, which was June 10, 2025; or (ii) the 2026 Annual Meeting of Shareholders..

SEC source: 0000929638-25-002249 · form4.xml · derivative · entry 1

Glickman Richard M · CIK 0001352637 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Shares · 22,500 shares

Expires 2035-06-16

F1 · derivative.exercise_date: This option fully vests on the earlier of (i) the first anniversary of the date vesting commenced, which was June 10, 2025; or (ii) the 2026 Annual Meeting of Shareholders.

SEC source: 0000929638-25-002248 · form4.xml · derivative · entry 1

BRUNK GERALD A · CIK 0001380226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,500

Underlying: Common Shares · 22,500 shares

Expires 2035-06-16

F1 · derivative.exercise_date: This option fully vests on the earlier of (i) the first anniversary of the date vesting commenced, which was June 10, 2025; or (ii) the 2026 Annual Meeting of Shareholders.

F2 · ownership.direct: These options are held of record by Mr. Brunk for the benefit of Lumira Ventures III, L.P. ("Lumira III"), Lumira Ventures III (International), L.P. ("Lumira III Int'l"), Lumira Ventures IV, L.P. ("Lumira IV"), Lumira Ventures IV (International), L.P. ("Lumira IV Int'l"), Merck Lumira Biosciences Fund, L.P. ("Merck-Lumira"), Merck Lumira Biosciences Fund (Quebec), L.P. ("Merck-Lumira B" and, together with Lumira III, Lumira III Int'l, Lumira IV, Lumira IV Int'l, and Merck-Lumira, the "Lumira Entities"). Mr. Brunk expressly disclaims beneficial ownership of these securities.

SEC source: 0000929638-25-002252 · form4.xml · derivative · entry 1

Pott Amy · CIK 0001787363 · Chief Global Comm. Ofc.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 400,000

Underlying: Common Shares · 400,000 shares

Expires 2035-06-16

F1 · derivative.exercise_date: Non-qualified stock option grant awarded as an inducement award outside of the Amended and Restated enGene Holdings Inc. 2023 Incentive Equity Plan in accordance with NASDAQ Listing Rule 5635(c)(4). This option vests at 25% on May 27, 2026, which is the first anniversary of the employment commencement date, with the remaining portion to vest monthly over the remaining three years, subject to the reporting person's continued service.

SEC source: 0000929638-25-000481 · form4.xml · derivative · entry 1

Pruthi Raj Som · CIK 0002030291 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 280,000

Underlying: Common Shares · 280,000 shares

Expires 2035-01-29

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-25-000478 · form4.xml · derivative · entry 1

Daws D. Ryan · CIK 0001598602 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 280,000

Underlying: Common Shares · 280,000 shares

Expires 2035-01-29

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-25-000476 · form4.xml · derivative · entry 1

Cooper Ronald Harold Wilfred · CIK 0001676880 · Director · CEO & President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 850,000

Underlying: Common Shares · 850,000 shares

Expires 2035-01-29

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-25-000479 · form4.xml · derivative · entry 1

Giguere Lee · CIK 0001796465 · Chief Legal Ofc. and Corp Secy

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Common Shares · 250,000 shares

Expires 2035-01-29

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-25-000480 · form4.xml · derivative · entry 1

Nichols Alexander Julian · CIK 0001998744 · Chief Strategy & Ops. Ofc

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Common Shares · 250,000 shares

Expires 2035-01-29

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000929638-25-000477 · form4.xml · derivative · entry 1

CHEUNG ANTHONY TZEYEW · CIK 0001998684 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Common Shares · 250,000 shares

Expires 2035-01-29

F1 · derivative.exercise_date: This option vests monthly in substantially equal amounts for 48 months, subject to the reporting person's continued service.

SEC source: 0000950170-24-120079 · ownership.xml · nonDerivative · entry 1

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 3,032,430

F1 · kind: On October 30, 2024, Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief") acquired 561,797 Common Shares in a private placement by the Issuer pursuant to the terms of a Subscription Agreement dated October 24, 2024.

F2 · ownership.direct: Shares held by Forbion Cooperatief. Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000929638-24-003557 · form4.xml · derivative · entry 1

Connolly Joan · CIK 0002041481 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 210,000

Underlying: Common Shares · 210,000 shares

Expires 2034-10-21

F1 · derivative.exercise_date: Non-qualified stock option grant awarded pursuant to the Employment Agreement dated October 21, 2024 between Ms. Connolly and enGene USA, Inc. as an inducement award outside of the Amended and Restated enGene Holdings Inc. 2023 Incentive Equity Plan in accordance with NASDAQ Listing Rule 5635(c)(4). This option vests at 25% on October 21, 2025, which is the first anniversary of the employment commencement date, with the remaining portion to vest monthly over the remaining three years, subject to Ms. Connolly's continued service.

SEC source: 0000929638-24-003559 · form4.xml · derivative · entry 1

CHEUNG ANTHONY TZEYEW · CIK 0001998684 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Shares · 100,000 shares

Expires 2034-10-21

F1 · derivative.exercise_date: This option vests at 25% on October 21, 2025, which is the first anniversary of the grant date, with the remaining portion to vest monthly over the remaining three years, subject to Dr. Cheung's continued service.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 13

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,470,633

F13 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.59 to $6.60, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 12

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,469,833

F12 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.42 to $6.60, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 11

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,457,989

F11 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.50 to $6.62, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 10

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,451,992

F10 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.435 to $6.585, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 9

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,446,223

F9 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.07 to $6.67, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 8

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,436,070

F8 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.30 to $6.60, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 7

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,400,791

F7 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.97 to $6.60, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000929638-24-003358 · form4.xml · nonDerivative · entry 1

Cooper Ronald Harold Wilfred · CIK 0001676880 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,000

F1 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.50 to $5.97, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in footnote (1) to this Form 4.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 6

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,059,459

F6 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $6.31 to $6.40, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000950170-24-115607 · ownership.xml · nonDerivative · entry 5

Forbion Growth Opportunities Fund I Cooperatief U.A. · CIK 0001911047 · 10% owner

Forbion Growth Management B.V. · CIK 0001918318 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 2,056,216

F5 · price: The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.31 to $6.30, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range.

F2 · ownership.direct: Shares held by Forbion Growth Opportunities Fund I Cooperatief U.A. ("Forbion Cooperatief"). Forbion Growth Management B.V. ("Forbion Management") is the sole director of Forbion Cooperatief and exercises voting and investment power through its investment committee (the "Management Investment Committee"), consisting of S. Slootweg, van Osch, G. J. Mulder, V. van Houten, D.A.F. Kersten, N.L. Luneborg, W.S.J. Joustra and J.M. Bos. None of the members of the Management Investment Committee has individual voting and investment power with respect to the securities reported herein. Each Reporting Person disclaims beneficial ownership of the securities reported herein, except to the extent of its pecuniary interest therein, if any.