DYN

SEC source: 0001209191-23-058666 · doc4.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 124,228

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 11, 2023.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $12.00 to $12.05, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range(s) set forth in this footnote of this Form 4.

SEC source: 0001209191-23-058328 · doc4.xml · nonDerivative · entry 2

Farwell Wildon · CIK 0001847941 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 169,096

F4 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 14, 2023.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.37 to $10.75, inclusive.

F3 · balance_after: Includes 145,667 unvested RSUs.

SEC source: 0001209191-23-058326 · doc4.xml · nonDerivative · entry 1

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 176,585

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.72 to $10.81, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 146,805 unvested RSUs.

SEC source: 0001209191-23-058332 · doc4.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 126,604

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.72 to $10.82, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 124,213 unvested RSUs.

SEC source: 0001209191-23-058330 · doc4.xml · nonDerivative · entry 1

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 155,518

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.72 to $10.82, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0001209191-23-058329 · doc4.xml · nonDerivative · entry 1

HIGH SUSANNA GATTI · CIK 0001691005 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 187,882

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.72 to $10.82, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 157,029 unvested RSUs.

SEC source: 0001209191-23-058328 · doc4.xml · nonDerivative · entry 1

Farwell Wildon · CIK 0001847941 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 170,074

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.72 to $10.82, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 145,667 unvested RSUs.

SEC source: 0001209191-23-058327 · doc4.xml · nonDerivative · entry 1

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 584,971

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.72 to $10.83, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0001209191-23-057671 · doc4.xml · nonDerivative · entry 2

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 127,984

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 11, 2023.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $12.00 to $12.04, inclusive.

SEC source: 0001209191-23-057671 · doc4.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 129,856

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 11, 2023.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $12.00 to $12.04, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range(s) set forth in this footnote of this Form 4.

SEC source: 0001209191-23-055521 · doc4.xml · derivative · entry 2

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,495

Underlying: Common Stock · 36,495 shares

Expires 2033-11-14

F3 · derivative.exercise_date: This option was granted on November 15, 2023. The shares underlying the option are scheduled to vest over four years in equal monthly installments through November 15, 2027.

SEC source: 0001209191-23-055521 · doc4.xml · nonDerivative · entry 1

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 178,052

F1 · shares: Consists of shares of Common Stock issuable under 93,718 restricted stock units ("RSUs"). Each RSU represents the right to receive one share of Common Stock upon vesting. These RSUs are scheduled to vest in equal quarterly installments over four years with the first installment vesting on February 15, 2024.

F2 · balance_after: Includes 151,588 unvested RSUs.

SEC source: 0001209191-23-055533 · doc4.xml · derivative · entry 2

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 34,946

Underlying: Common Stock · 34,946 shares

Expires 2033-11-14

F3 · derivative.exercise_date: This option was granted on November 15, 2023. The shares underlying the option are scheduled to vest over four years in equal monthly installments through November 15, 2027.

SEC source: 0001209191-23-055533 · doc4.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 130,537

F1 · shares: Consists of shares of Common Stock issuable under 89,742 restricted stock units ("RSUs"). Each RSU represents the right to receive one share of Common Stock upon vesting. These RSUs are scheduled to vest in equal quarterly installments over four years with the first installment vesting on February 15, 2024.

F2 · balance_after: Includes 127,193 unvested RSUs.

SEC source: 0001209191-23-055526 · doc4.xml · derivative · entry 2

HIGH SUSANNA GATTI · CIK 0001691005 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 36,952

Underlying: Common Stock · 36,952 shares

Expires 2033-11-14

F3 · derivative.exercise_date: This option was granted on November 15, 2023. The shares underlying the option are scheduled to vest over four years in equal monthly installments through November 15, 2027.

SEC source: 0001209191-23-055526 · doc4.xml · nonDerivative · entry 1

HIGH SUSANNA GATTI · CIK 0001691005 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 189,498

F1 · shares: Consists of shares of Common Stock issuable under 94,893 restricted stock units ("RSUs"). Each RSU represents the right to receive one share of Common Stock upon vesting. These RSUs are scheduled to vest in equal quarterly installments over four years with the first installment vesting on February 15, 2024.

F2 · balance_after: Includes 162,299 unvested RSUs.

SEC source: 0001209191-23-055530 · doc4.xml · derivative · entry 2

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 37,445

Underlying: Common Stock · 37,445 shares

Expires 2033-11-14

F3 · derivative.exercise_date: This option was granted on November 15, 2023. The shares underlying the option are scheduled to vest over four years in equal monthly installments through November 15, 2027.

SEC source: 0001209191-23-055530 · doc4.xml · nonDerivative · entry 1

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 156,763

F1 · shares: Consists of shares of Common Stock issuable under 96,158 restricted stock units ("RSUs"). Each RSU represents the right to receive one share of Common Stock upon vesting. These RSUs are scheduled to vest in equal quarterly installments over four years with the first installment vesting on February 15, 2024.

F2 · balance_after: Includes 147,149 unvested RSUs.

SEC source: 0001209191-23-055524 · doc4.xml · derivative · entry 2

Farwell Wildon · CIK 0001847941 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,131

Underlying: Common Stock · 32,131 shares

Expires 2033-11-14

F3 · derivative.exercise_date: This option was granted on November 15, 2023. The shares underlying the option are scheduled to vest over four years in equal monthly installments through November 15, 2027.

SEC source: 0001209191-23-055524 · doc4.xml · nonDerivative · entry 1

Farwell Wildon · CIK 0001847941 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 171,762

F1 · shares: Consists of shares of Common Stock issuable under 82,512 restricted stock units ("RSUs"). Each RSU represents the right to receive one share of Common Stock upon vesting. These RSUs are scheduled to vest in equal quarterly installments over four years with the first installment vesting on February 15, 2024.

F2 · balance_after: Includes 149,311 unvested RSUs.

SEC source: 0001209191-23-055523 · doc4.xml · derivative · entry 2

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 139,750

Underlying: Common Stock · 139,750 shares

Expires 2033-11-14

F3 · derivative.exercise_date: This option was granted on November 15, 2023. The shares underlying the option are scheduled to vest over four years in equal monthly installments through November 15, 2027.

SEC source: 0001209191-23-055523 · doc4.xml · nonDerivative · entry 1

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 592,556

F1 · shares: Consists of shares of Common Stock issuable under 358,877 restricted stock units ("RSUs"). Each RSU represents the right to receive one share of Common Stock upon vesting. These RSUs are scheduled to vest in equal quarterly installments over four years with the first installment vesting on February 15, 2024.

F2 · balance_after: Includes 569,116 unvested RSUs.

SEC source: 0001209191-23-054194 · doc4.xml · nonDerivative · entry 1

HIGH SUSANNA GATTI · CIK 0001691005 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 94,605

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 10, 2023.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $7.12 to $7.60, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range(s) set forth in this footnote of this Form 4.

SEC source: 0001209191-23-050168 · doc4.xml · nonDerivative · entry 1

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 84,334

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on September 17, 2020. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 57,870 unvested RSUs.

SEC source: 0001209191-23-050174 · doc4.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,795

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on September 17, 2020. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 37,451 unvested RSUs.

SEC source: 0001209191-23-050172 · doc4.xml · nonDerivative · entry 1

HIGH SUSANNA GATTI · CIK 0001691005 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 104,544

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on September 17, 2020. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 67,406 unvested RSUs.

SEC source: 0001209191-23-050173 · doc4.xml · nonDerivative · entry 1

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 60,605

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on September 17, 2020. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 50,991 unvested RSUs.

SEC source: 0001209191-23-050169 · doc4.xml · nonDerivative · entry 1

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 233,679

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on September 17, 2020. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 210,239 unvested RSUs.

SEC source: 0001209191-23-049356 · doc4.xml · nonDerivative · entry 1

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,770

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.08 to $10.43, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 62,692 unvested RSUs.

SEC source: 0001209191-23-049362 · doc4.xml · nonDerivative · entry 1

Farwell Wildon · CIK 0001847941 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 89,250

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.07 to $10.43, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 66,799 unvested RSUs.

SEC source: 0001209191-23-049361 · doc4.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 42,085

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.07 to $10.43, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 40,317 unvested RSUs.

SEC source: 0001209191-23-049360 · doc4.xml · nonDerivative · entry 1

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,866

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.08 to $10.43, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range(s) set forth in this footnote of this Form 4.

F2 · balance_after: Includes 55,244 unvested RSUs.

SEC source: 0001209191-23-049359 · doc4.xml · nonDerivative · entry 1

HIGH SUSANNA GATTI · CIK 0001691005 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,216

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.09 to $10.43, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 76,382 unvested RSUs.

SEC source: 0001209191-23-049357 · doc4.xml · nonDerivative · entry 1

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 245,711

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $10.09 to $10.43, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 236,996 unvested RSUs.

SEC source: 0000950170-24-042032 · ownership.xml · derivative · entry 1

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 35,000

Underlying: Common Stock · 35,000 shares

Expires 2033-07-10

F1 · date: This transaction is being reported late due to an inadvertent administrative error.

F2 · derivative.exercise_date: This option award was granted on July 11, 2023 and vests over four years in equal monthly installments, with the first vesting occurring on August 1, 2023 and the remaining vesting occurring each month subsequent to the first vesting date, subject to continuous service.

SEC source: 0001209191-23-037487 · doc4.xml · nonDerivative · entry 4

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 43,482

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $12.00 to $12.16, inclusive.

SEC source: 0001209191-23-037163 · doc4.xml · nonDerivative · entry 1

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 87,254

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 67,475 unvested RSUs.

SEC source: 0001209191-23-037167 · doc4.xml · nonDerivative · entry 2

McNeill Jonathan · CIK 0001824673 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 63,132

F4 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F3 · balance_after: Includes 59,326 unvested RSUs.

SEC source: 0001209191-23-037166 · doc4.xml · nonDerivative · entry 1

HIGH SUSANNA GATTI · CIK 0001691005 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 108,851

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 81,652 unvested RSUs.

SEC source: 0001209191-23-037165 · doc4.xml · nonDerivative · entry 1

Farwell Wildon · CIK 0001847941 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,957

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 70,443 unvested RSUs.

SEC source: 0001209191-23-037487 · doc4.xml · derivative · entry 5

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 38,740

Underlying: Common Stock · 40,000 shares

Expires 2030-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option was granted on January 6, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on December 2, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0001209191-23-037487 · doc4.xml · nonDerivative · entry 3

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,482

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $12.75 to $13.05, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (1) and (2) of this Form 4.

SEC source: 0001209191-23-037487 · doc4.xml · nonDerivative · entry 2

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 93,482

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-23-037487 · doc4.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,482

F1 · shares: Represents shares automatically sold by the Reporting Person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted to the Reporting Person on December 10, 2021 and December 9, 2022. The automatic sale of the Reporting Person's shares is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the Reporting Person.

F2 · balance_after: Includes 43,297 unvested RSUs.

SEC source: 0001209191-23-036544 · doc4.xml · derivative · entry 12

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 69,719

Underlying: Common Stock · 171,360 shares

Expires 2023-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option was granted on January 6, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on October 12, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0001209191-23-036544 · doc4.xml · nonDerivative · entry 9

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 253,383

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $12.18 to $13.14, inclusive.

SEC source: 0001209191-23-036544 · doc4.xml · nonDerivative · entry 8

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 441,131

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-23-037167 · doc4.xml · nonDerivative · entry 1

McNeill Jonathan · CIK 0001824673 · See Remarks

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 64,391

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 7, 2022.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $12.95 to $13.03, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range(s) set forth in this footnote of this Form 4.

F3 · balance_after: Includes 59,326 unvested RSUs.

SEC source: 0001209191-23-036544 · doc4.xml · derivative · entry 11

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 241,079

Underlying: Common Stock · 76,582 shares

Expires 2030-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: The option was granted on January 6, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on October 12, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0001209191-23-036544 · doc4.xml · nonDerivative · entry 7

Brumm Joshua T · CIK 0001528826 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 269,771

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $13.00 to $13.64, inclusive.