DYN

SEC source: 0001415889-24-004467 · form4-02202024_110225.xml · nonDerivative · entry 5

Atlas Venture Fund XI, L.P. · CIK 0001708269 · 10% owner

Atlas Venture Associates XI, L.P. · CIK 0001780068 · 10% owner

Atlas Venture Associates XI, LLC · CIK 0001780067 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,815,965

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Atlas Venture Fund XI, L.P. on January 10, 2024.

F7 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $23.16 to $24.01 inclusive.

F3 · ownership.direct: The shares are held directly by Atlas Venture Fund XI, L.P. ("Atlas Venture Fund XI"). The general partner of Atlas Venture Fund XI is Atlas Venture Associates XI, L.P. ("AVA XI LP"). Atlas Venture Associates XI, LLC ("AVA XI LLC") is the general partner of AVA XI LP. Each of AVA XI LP and AVA XI LLC disclaims Section 16 beneficial ownership of the securities held by Atlas Venture Fund XI, except to the extent of its pecuniary interest therein, if any.

SEC source: 0001415889-24-004467 · form4-02202024_110225.xml · nonDerivative · entry 4

Atlas Venture Fund XI, L.P. · CIK 0001708269 · 10% owner

Atlas Venture Associates XI, L.P. · CIK 0001780068 · 10% owner

Atlas Venture Associates XI, LLC · CIK 0001780067 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,819,475

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Atlas Venture Fund XI, L.P. on January 10, 2024.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.117 to $23.09 inclusive.

F3 · ownership.direct: The shares are held directly by Atlas Venture Fund XI, L.P. ("Atlas Venture Fund XI"). The general partner of Atlas Venture Fund XI is Atlas Venture Associates XI, L.P. ("AVA XI LP"). Atlas Venture Associates XI, LLC ("AVA XI LLC") is the general partner of AVA XI LP. Each of AVA XI LP and AVA XI LLC disclaims Section 16 beneficial ownership of the securities held by Atlas Venture Fund XI, except to the extent of its pecuniary interest therein, if any.

SEC source: 0001415889-24-004471 · form4-02202024_110236.xml · nonDerivative · entry 3

Rhodes Jason P · CIK 0001577014 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · See footnote

Disclosed balance after: 6,985,504

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Atlas Venture Fund XI, L.P. on January 10, 2024.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.878 to $23.54 inclusive.

F3 · ownership.nature: The shares are held directly by Atlas Venture Fund XI, L.P. ("Atlas Venture Fund XI"). The general partner of Atlas Venture Fund XI is Atlas Venture Associates XI, L.P. ("AVA XI LP"). Atlas Venture Associates XI, LLC ("AVA XI LLC") is the general partner of AVA XI LP. The Reporting Person is a member of AVA XI LLC and disclaims beneficial ownership of such securities held by Atlas Venture Fund XI, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001415889-24-004467 · form4-02202024_110225.xml · nonDerivative · entry 3

Atlas Venture Fund XI, L.P. · CIK 0001708269 · 10% owner

Atlas Venture Associates XI, L.P. · CIK 0001780068 · 10% owner

Atlas Venture Associates XI, LLC · CIK 0001780067 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 6,985,504

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Atlas Venture Fund XI, L.P. on January 10, 2024.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $22.878 to $23.54 inclusive.

F3 · ownership.direct: The shares are held directly by Atlas Venture Fund XI, L.P. ("Atlas Venture Fund XI"). The general partner of Atlas Venture Fund XI is Atlas Venture Associates XI, L.P. ("AVA XI LP"). Atlas Venture Associates XI, LLC ("AVA XI LLC") is the general partner of AVA XI LP. Each of AVA XI LP and AVA XI LLC disclaims Section 16 beneficial ownership of the securities held by Atlas Venture Fund XI, except to the extent of its pecuniary interest therein, if any.

SEC source: 0001415889-24-004471 · form4-02202024_110236.xml · nonDerivative · entry 2

Rhodes Jason P · CIK 0001577014 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · See footnote

Disclosed balance after: 7,148,211

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Atlas Venture Fund XI, L.P. on January 10, 2024.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $24.40 to $24.51 inclusive.

F3 · ownership.nature: The shares are held directly by Atlas Venture Fund XI, L.P. ("Atlas Venture Fund XI"). The general partner of Atlas Venture Fund XI is Atlas Venture Associates XI, L.P. ("AVA XI LP"). Atlas Venture Associates XI, LLC ("AVA XI LLC") is the general partner of AVA XI LP. The Reporting Person is a member of AVA XI LLC and disclaims beneficial ownership of such securities held by Atlas Venture Fund XI, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001415889-24-004471 · form4-02202024_110236.xml · nonDerivative · entry 1

Rhodes Jason P · CIK 0001577014 · Director

10b5-1 filing: Plan reported

Ownership: Indirect · See footnote

Disclosed balance after: 7,150,324

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Atlas Venture Fund XI, L.P. on January 10, 2024.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $23.40 to $24.3943 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (4), (5), (6) and (7).

F3 · ownership.nature: The shares are held directly by Atlas Venture Fund XI, L.P. ("Atlas Venture Fund XI"). The general partner of Atlas Venture Fund XI is Atlas Venture Associates XI, L.P. ("AVA XI LP"). Atlas Venture Associates XI, LLC ("AVA XI LLC") is the general partner of AVA XI LP. The Reporting Person is a member of AVA XI LLC and disclaims beneficial ownership of such securities held by Atlas Venture Fund XI, except to the extent of his pecuniary interest therein, if any.

SEC source: 0001415889-24-004467 · form4-02202024_110225.xml · nonDerivative · entry 2

Atlas Venture Fund XI, L.P. · CIK 0001708269 · 10% owner

Atlas Venture Associates XI, L.P. · CIK 0001780068 · 10% owner

Atlas Venture Associates XI, LLC · CIK 0001780067 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,148,211

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Atlas Venture Fund XI, L.P. on January 10, 2024.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $24.40 to $24.51 inclusive.

F3 · ownership.direct: The shares are held directly by Atlas Venture Fund XI, L.P. ("Atlas Venture Fund XI"). The general partner of Atlas Venture Fund XI is Atlas Venture Associates XI, L.P. ("AVA XI LP"). Atlas Venture Associates XI, LLC ("AVA XI LLC") is the general partner of AVA XI LP. Each of AVA XI LP and AVA XI LLC disclaims Section 16 beneficial ownership of the securities held by Atlas Venture Fund XI, except to the extent of its pecuniary interest therein, if any.

SEC source: 0001415889-24-004467 · form4-02202024_110225.xml · nonDerivative · entry 1

Atlas Venture Fund XI, L.P. · CIK 0001708269 · 10% owner

Atlas Venture Associates XI, L.P. · CIK 0001780068 · 10% owner

Atlas Venture Associates XI, LLC · CIK 0001780067 · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,150,324

F1 · kind: This transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Atlas Venture Fund XI, L.P. on January 10, 2024.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $23.40 to $24.3943 inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (4), (5), (6) and (7).

F3 · ownership.direct: The shares are held directly by Atlas Venture Fund XI, L.P. ("Atlas Venture Fund XI"). The general partner of Atlas Venture Fund XI is Atlas Venture Associates XI, L.P. ("AVA XI LP"). Atlas Venture Associates XI, LLC ("AVA XI LLC") is the general partner of AVA XI LP. Each of AVA XI LP and AVA XI LLC disclaims Section 16 beneficial ownership of the securities held by Atlas Venture Fund XI, except to the extent of its pecuniary interest therein, if any.

SEC source: 0000950170-24-015259 · ownership.xml · nonDerivative · entry 1

Farwell Wildon · CIK 0001847941 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 163,503

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 14, 2023.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $25.00 to $25.16, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote of this Form 4.

F3 · balance_after: Includes 145,667 unvested RSUs.

SEC source: 0000950170-24-009406 · ownership.xml · nonDerivative · entry 2

Brumm Joshua T · CIK 0001528826 · Director · CEO & President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 563,471

F1 · kind: This transaction was a charitable donation to a third party effective January 29, 2024 in which no value was received in return.

F2 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-009406 · ownership.xml · nonDerivative · entry 1

Brumm Joshua T · CIK 0001528826 · Director · CEO & President

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 564,971

F1 · kind: This transaction was a charitable donation to a third party effective January 29, 2024 in which no value was received in return.

F2 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-008063 · ownership.xml · nonDerivative · entry 1

Farwell Wildon · CIK 0001847941 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 168,996

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 14, 2023.

F2 · balance_after: Includes 145,667 unvested RSUs.

SEC source: 0000950170-24-008062 · ownership.xml · derivative · entry 4

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 28,528

Underlying: Common Stock · 20,000 shares

Expires 2029-02-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: The option was granted on February 26, 2019. The shares underlying the option vest over four years, with 25% of the shares vesting on February 1, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0000950170-24-008062 · ownership.xml · nonDerivative · entry 3

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,618

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $25.01 to $25.25, inclusive.

F1 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0000950170-24-008062 · ownership.xml · nonDerivative · entry 2

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,796

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $24.00 to $24.99, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the footnotes of this Form 4.

F1 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0000950170-24-008062 · ownership.xml · nonDerivative · entry 1

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 163,618

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0000950170-24-008061 · ownership.xml · derivative · entry 3

Scalzo Richard William · CIK 0001789545 · SVP, Head of Finance & Admin.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 12,740

Underlying: Common Stock · 13,000 shares

Expires 2030-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option was granted on January 6, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on December 2, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0000950170-24-008061 · ownership.xml · nonDerivative · entry 2

Scalzo Richard William · CIK 0001789545 · SVP, Head of Finance & Admin.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 124,228

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 11, 2023.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $24.00 to $25.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote of this Form 4.

F1 · balance_after: Includes 124,213 unvested RSUs.

SEC source: 0000950170-24-008061 · ownership.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · SVP, Head of Finance & Admin.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 137,228

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 124,213 unvested RSUs.

SEC source: 0000950170-24-003943 · ownership.xml · nonDerivative · entry 2

Kersten Dirk · CIK 0001823682 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 1,428,571

F2 · ownership.nature: The shares are held directly by Forbion Growth Opportunities Fund II Cooperatief U.A ("FGO II "). Forbion Growth II Management B.V. ("FGO II Management") the director of FGO II, may be deemed to have voting and dispositive power over the shares held by FGO II. Investment decisions with respect to the shares held by FGO II can be made by FCPM III Services B.V., the director of FGO II Management, which may delegate such powers to its investment committee which may delegate such powers to the authorized representatives of FGO II Management. Messrs. Slootweg, van Osch, Mulder, van Houten, Reithinger and Boorsma (the "Partners") are partners of FCPM III Services B.V., which acts as the investment advisor to the directors of FGO II. The Reporting Person is a partner of FGO II Management and a member of the investment committee of FGO II Management. The Reporting Person disclaims beneficial ownership of the shares, except to the extent of his pecuniary interest therein.

SEC source: 0000950170-24-003943 · ownership.xml · nonDerivative · entry 1

Kersten Dirk · CIK 0001823682 · Director · 10% owner

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnote

Disclosed balance after: 6,416,793

F1 · ownership.nature: The shares are held directly by Forbion Capital Fund IV Cooperatief U.A ("FCF IV"). Forbion IV Management B.V. ("Forbion Management") the director of FCF IV, may be deemed to have voting and dispositive power over the shares held by FCF IV. Investment decisions with respect to the shares held by FCF IV can be made by FCPM III Services B.V., the director of Forbion Management, which may delegate such powers to its investment committee which may delegate such powers to the authorized representatives of Forbion Management. Messrs. Slootweg, van Osch, Mulder, van Houten, Reithinger and Boorsma (the "Partners") are partners of FCPM III Services B.V., which acts as the investment advisor to the directors of FCF IV. The Reporting Person is a partner of Forbion Management and a member of the investment committee of Forbion Management. The Reporting Person disclaims beneficial ownership of the shares, except to the extent of his pecuniary interest therein.

SEC source: 0000950170-24-002279 · ownership.xml · nonDerivative · entry 6

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 156,806

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 30, 2023.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $18.00 to $18.45, inclusive.

F1 · balance_after: Includes 146,805 unvested RSUs.

SEC source: 0000950170-24-002279 · ownership.xml · nonDerivative · entry 5

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 199,259

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 146,805 unvested RSUs.

SEC source: 0000950170-24-002280 · ownership.xml · derivative · entry 11

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 107,863

Underlying: Common Stock · 200,000 shares

Expires 2030-07-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F8 · derivative.exercise_date: The option was granted on July 31, 2020. The shares underlying the option vest over four years in equal quarterly installments through July 31, 2024.

SEC source: 0000950170-24-002280 · ownership.xml · derivative · entry 10

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 18,536 shares

Expires 2030-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option was granted on January 6, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on October 12, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0000950170-24-002280 · ownership.xml · nonDerivative · entry 8

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 584,971

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $19.00 to $19.25, inclusive.

F1 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-002280 · ownership.xml · nonDerivative · entry 7

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 623,272

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $18.00 to $18.93, inclusive.

F1 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-002280 · ownership.xml · nonDerivative · entry 6

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 803,507

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-002280 · ownership.xml · nonDerivative · entry 5

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 603,507

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-002278 · ownership.xml · derivative · entry 8

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 48,528

Underlying: Common Stock · 2,009 shares

Expires 2029-02-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option was granted on February 26, 2019. The shares underlying the option vest over four years, with 25% of the shares vesting on February 1, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0000950170-24-002278 · ownership.xml · nonDerivative · entry 6

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,618

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F6 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $18.00 to $18.07, inclusive.

F3 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0000950170-24-002278 · ownership.xml · nonDerivative · entry 5

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 145,627

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0000950170-24-002279 · ownership.xml · derivative · entry 7

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 53,100

Underlying: Common Stock · 45,326 shares

Expires 2030-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option was granted on January 6, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on January 27, 2021 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0000950170-24-002279 · ownership.xml · nonDerivative · entry 4

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 176,585

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 30, 2023.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $20.50 to $20.56, inclusive.

F1 · balance_after: Includes 146,805 unvested RSUs.

SEC source: 0000950170-24-002279 · ownership.xml · nonDerivative · entry 3

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 181,946

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 30, 2023.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $19.00 to $19.25, inclusive.

F1 · balance_after: Includes 146,805 unvested RSUs.

SEC source: 0000950170-24-002279 · ownership.xml · nonDerivative · entry 2

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 206,529

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 30, 2023.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $18.00 to $18.50, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the footnotes of this Form 4.

F1 · balance_after: Includes 146,805 unvested RSUs.

SEC source: 0000950170-24-002279 · ownership.xml · nonDerivative · entry 1

Beskrovnaya Oxana · CIK 0001824542 · Chief Scientific Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 221,911

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 146,805 unvested RSUs.

SEC source: 0000950170-24-002280 · ownership.xml · derivative · entry 9

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 18,536

Underlying: Common Stock · 51,183 shares

Expires 2030-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option was granted on January 6, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on October 12, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0000950170-24-002280 · ownership.xml · nonDerivative · entry 4

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 584,971

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $20.50 to $20.58, inclusive.

F1 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-002280 · ownership.xml · nonDerivative · entry 3

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 600,997

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $19.00 to $19.25, inclusive.

F1 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-002280 · ownership.xml · nonDerivative · entry 2

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 620,772

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $18.00 to $18.65, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the footnotes of this Form 4.

F1 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-002280 · ownership.xml · nonDerivative · entry 1

Brumm Joshua T · CIK 0001528826 · CEO & President

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 636,154

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 552,729 unvested RSUs.

SEC source: 0000950170-24-002278 · ownership.xml · derivative · entry 7

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 50,537

Underlying: Common Stock · 17,991 shares

Expires 2029-02-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: The option was granted on February 26, 2019. The shares underlying the option vest over four years, with 25% of the shares vesting on February 1, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0000950170-24-002278 · ownership.xml · nonDerivative · entry 4

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,618

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F5 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $19.00 to $19.25, inclusive.

F3 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0000950170-24-002278 · ownership.xml · nonDerivative · entry 3

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 153,918

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F4 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $18.00 to $18.50, inclusive.

F3 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0000950170-24-002278 · ownership.xml · nonDerivative · entry 2

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 161,609

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · balance_after: Includes 143,067 unvested RSUs.

SEC source: 0000950170-24-002277 · ownership.xml · derivative · entry 3

Scalzo Richard William · CIK 0001789545 · SVP, Head of Finance & Admin.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 25,740

Underlying: Common Stock · 13,000 shares

Expires 2030-01-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: The option was granted on January 6, 2020. The shares underlying the option vest over four years, with 25% of the shares vesting on December 2, 2020 and the remaining shares vesting in equal quarterly installments thereafter.

SEC source: 0000950170-24-002277 · ownership.xml · nonDerivative · entry 2

Scalzo Richard William · CIK 0001789545 · SVP, Head of Finance & Admin.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 124,228

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on July 11, 2023.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $18.50 to $19.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote of this Form 4.

F1 · balance_after: Includes 124,213 unvested RSUs.

SEC source: 0000950170-24-002277 · ownership.xml · nonDerivative · entry 1

Scalzo Richard William · CIK 0001789545 · SVP, Head of Finance & Admin.

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 137,228

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 124,213 unvested RSUs.

SEC source: 0000950170-24-002278 · ownership.xml · nonDerivative · entry 1

McNeill Jonathan · CIK 0001824673 · Chief Business Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 143,618

F1 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 29, 2023.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices within the range of $12.76 to $13.50, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in the footnotes of this Form 4.

F3 · balance_after: Includes 143,067 unvested RSUs.