Last 12 months
Inside the activity.
0 purchase rows · 83 sale rows
Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.Monthly counts
| Month | Purchases | Sales |
|---|---|---|
| Nov 2025 | 0 | 4 |
| Dec 2025 | 0 | 9 |
| Jan 2026 | 0 | 3 |
| Feb 2026 | 0 | 2 |
| Mar 2026 | 0 | 17 |
| Apr 2026 | 0 | 8 |
| May 2026 | 0 | 9 |
| Jun 2026 | 0 | 8 |
| Jul 2026 | 0 | 9 |
| Aug 2026 | 0 | 4 |
| Sep 2026 | 0 | 8 |
| Oct 2026 | 0 | 2 |
Latest available
Insider transactions
Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”
The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.
| Transaction date | Owner / reported role | Activity / security | Shares / units | Reported price | Reported value | Details |
|---|---|---|---|---|---|---|
| April 15, 2026 Filed Apr 15, 2026 22:37 UTC |
Wysenski NancyDirector
|
GrantCommon Stock | 95 | $65.37 | $6,210.15 |
DisclosureSEC source: 0001061983-26-000042 · form4.xml · nonDerivative · entry 1 Wysenski Nancy · CIK 0001294596 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 31,066 F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested. Read SEC document |
| April 15, 2026 Filed Apr 15, 2026 22:35 UTC |
Kaye Edward M. MDDirector
|
GrantCommon Stock | 191 | $65.37 | $12,485.67 |
DisclosureSEC source: 0001061983-26-000040 · form4.xml · nonDerivative · entry 1 Kaye Edward M. MD · CIK 0001522780 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 10,365 F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested. Read SEC document |
| April 15, 2026 Filed Apr 15, 2026 22:36 UTC |
WIERENGA WENDELLDirector
|
GrantCommon Stock | 95 | $65.37 | $6,210.15 |
DisclosureSEC source: 0001061983-26-000041 · form4.xml · nonDerivative · entry 1 WIERENGA WENDELL · CIK 0001239956 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 32,637 F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested. Read SEC document |
| April 15, 2026 Filed Apr 15, 2026 22:34 UTC |
HENDERSON JOHN TDirector
|
GrantCommon Stock | 325 | $65.37 | $21,245.25 |
DisclosureSEC source: 0001061983-26-000039 · form4.xml · nonDerivative · entry 1 HENDERSON JOHN T · CIK 0001226488 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 75,237 F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested. Read SEC document |
| April 15, 2026 Filed Apr 15, 2026 22:33 UTC |
Harrington Robert ArthurDirector
|
GrantCommon Stock | 191 | $65.37 | $12,485.67 |
DisclosureSEC source: 0001061983-26-000038 · form4.xml · nonDerivative · entry 1 Harrington Robert Arthur · CIK 0001923988 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 18,930 F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested. Read SEC document |
| April 15, 2026 Filed Apr 15, 2026 21:27 UTC |
Blum Robert IDirector · President & CEO
|
SaleCommon Stock | 7,500 | $65.38 | $490,350.00 |
DisclosureSEC source: 0001061983-26-000035 · form4.xml · nonDerivative · entry 1 Blum Robert I · CIK 0001288859 · Director · President & CEO 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 415,330 Read SEC document |
| April 15, 2026 Filed Apr 15, 2026 22:32 UTC |
Daly James MDirector
|
GrantCommon Stock | 191 | $65.37 | $12,485.67 |
DisclosureSEC source: 0001061983-26-000037 · form4.xml · nonDerivative · entry 1 Daly James M · CIK 0001560782 · Director 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 388 F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested. Read SEC document |
| April 15, 2026 Filed Apr 15, 2026 21:29 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 7,449 | $66.02 | $491,782.98 |
DisclosureSEC source: 0001061983-26-000036 · form4.xml · nonDerivative · entry 1 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 58,555 Read SEC document |
| April 07, 2026 Filed Apr 8, 2026 20:18 UTC |
Malik Fady IbrahamEVP Research & Development
|
Exercise / conversionNon-Qualified Stock Option (Right to Buy) · Derivative | 1,000 | $0.00 Strike: $10.60 | $0.00 |
DisclosureSEC source: 0001061983-26-000034 · form4.xml · derivative · entry 6 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 0 Underlying: Common Stock · 1,000 shares Expires 2027-02-28 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 07, 2026 Filed Apr 8, 2026 20:18 UTC |
Malik Fady IbrahamEVP Research & Development
|
Exercise / conversionNon-Qualified Stock Option (Right to Buy) · Derivative | 3,500 | $0.00 Strike: $7.80 | $0.00 |
DisclosureSEC source: 0001061983-26-000034 · form4.xml · derivative · entry 5 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 58,386 Underlying: Common Stock · 3,500 shares Expires 2028-02-27 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 07, 2026 Filed Apr 8, 2026 20:18 UTC |
Malik Fady IbrahamEVP Research & Development
|
SaleCommon Stock | 1,000 | $64.75 | $64,750.00 |
DisclosureSEC source: 0001061983-26-000034 · form4.xml · nonDerivative · entry 4 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 153,902 Read SEC document |
| April 07, 2026 Filed Apr 8, 2026 20:18 UTC |
Malik Fady IbrahamEVP Research & Development
|
Exercise / conversionCommon Stock | 1,000 | $10.60 | $10,600.00 |
DisclosureSEC source: 0001061983-26-000034 · form4.xml · nonDerivative · entry 3 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 154,902 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 07, 2026 Filed Apr 8, 2026 20:18 UTC |
Malik Fady IbrahamEVP Research & Development
|
SaleCommon Stock | 3,500 | $65.21 | $228,235.00 |
DisclosureSEC source: 0001061983-26-000034 · form4.xml · nonDerivative · entry 2 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 153,902 Read SEC document |
| April 07, 2026 Filed Apr 8, 2026 20:18 UTC |
Malik Fady IbrahamEVP Research & Development
|
Exercise / conversionCommon Stock | 3,500 | $7.80 | $27,300.00 |
DisclosureSEC source: 0001061983-26-000034 · form4.xml · nonDerivative · entry 1 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 157,402 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| April 01, 2026 Filed Apr 1, 2026 20:34 UTC |
Blum Robert IDirector · President & CEO
|
SaleCommon Stock | 7,500 | $66.63 | $499,725.00 |
DisclosureSEC source: 0001061983-26-000031 · form4.xml · nonDerivative · entry 1 Blum Robert I · CIK 0001288859 · Director · President & CEO 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 422,830 Read SEC document |
| March 31, 2026 Filed Mar 31, 2026 20:21 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 3,639 | $65.00 | $236,535.00 |
DisclosureSEC source: 0001061983-26-000030 · form4.xml · nonDerivative · entry 1 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 66,004 Read SEC document |
| March 18, 2026 Filed Mar 18, 2026 20:55 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 1,930 | $62.07 | $119,795.10 |
DisclosureSEC source: 0001061983-26-000025 · form4.xml · nonDerivative · entry 1 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 78,185 Read SEC document |
| March 17, 2026 Filed Mar 18, 2026 21:46 UTC |
Lee SungEVP, Chief Financial Officer
|
SaleCommon Stock | 4,935 | $62.15 | $306,710.25 |
DisclosureSEC source: 0001061983-26-000029 · form4.xml · nonDerivative · entry 1 Lee Sung · CIK 0001793200 · EVP, Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 87,127 F1 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting. Read SEC document |
| March 17, 2026 Filed Mar 18, 2026 21:43 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 2,916 | $62.15 | $181,229.40 |
DisclosureSEC source: 0001061983-26-000028 · form4.xml · nonDerivative · entry 2 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 71,573 F2 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting. Read SEC document |
| March 17, 2026 Filed Mar 18, 2026 21:43 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 5,626 | $62.15 | $349,655.90 |
DisclosureSEC source: 0001061983-26-000028 · form4.xml · nonDerivative · entry 1 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 74,489 F1 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting. Read SEC document |
| March 17, 2026 Filed Mar 18, 2026 21:40 UTC |
Malik Fady IbrahamEVP Research & Development
|
SaleCommon Stock | 4,397 | $62.15 | $273,273.55 |
DisclosureSEC source: 0001061983-26-000027 · form4.xml · nonDerivative · entry 2 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 153,902 F2 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting. Read SEC document |
| March 17, 2026 Filed Mar 18, 2026 21:40 UTC |
Malik Fady IbrahamEVP Research & Development
|
SaleCommon Stock | 7,636 | $62.15 | $474,577.40 |
DisclosureSEC source: 0001061983-26-000027 · form4.xml · nonDerivative · entry 1 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 158,299 F1 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting. Read SEC document |
| March 17, 2026 Filed Mar 18, 2026 21:37 UTC |
Blum Robert IDirector · President & CEO
|
SaleCommon Stock | 23,928 | $62.15 | $1,487,125.20 |
DisclosureSEC source: 0001061983-26-000026 · form4.xml · nonDerivative · entry 2 Blum Robert I · CIK 0001288859 · Director · President & CEO 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 430,330 F2 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting. Read SEC document |
| March 17, 2026 Filed Mar 18, 2026 21:37 UTC |
Blum Robert IDirector · President & CEO
|
SaleCommon Stock | 12,673 | $62.15 | $787,626.95 |
DisclosureSEC source: 0001061983-26-000026 · form4.xml · nonDerivative · entry 1 Blum Robert I · CIK 0001288859 · Director · President & CEO 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 454,258 F1 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting. Read SEC document |
| March 16, 2026 Filed Mar 16, 2026 21:14 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 1,709 | $61.03 | $104,300.27 |
DisclosureSEC source: 0001061983-26-000019 · form4.xml · nonDerivative · entry 1 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 46,149 Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:05 UTC |
Lee SungEVP, Chief Financial Officer
|
GrantNon-Qualified Stock Option (Right to Buy) · Derivative | 29,480 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000021 · form4.xml · derivative · entry 3 Lee Sung · CIK 0001793200 · EVP, Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 29,480 Underlying: Common Stock · 29,480 shares Expires 2036-03-14 F3 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:05 UTC |
Lee SungEVP, Chief Financial Officer
|
GrantIncentive Stock Option (Right to Buy) · Derivative | 1,665 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000021 · form4.xml · derivative · entry 2 Lee Sung · CIK 0001793200 · EVP, Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,665 Underlying: Common Stock · 1,665 shares Expires 2036-03-14 F2 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:05 UTC |
Lee SungEVP, Chief Financial Officer
|
GrantCommon Stock | 20,646 | $0.00 | $0.00 |
DisclosureSEC source: 0001061983-26-000021 · form4.xml · nonDerivative · entry 1 Lee Sung · CIK 0001793200 · EVP, Chief Financial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 92,062 F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:11 UTC |
Blum Robert IDirector · President & CEO
|
GrantNon-Qualified Stock Option (Right to Buy) · Derivative | 111,864 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000024 · form4.xml · derivative · entry 5 Blum Robert I · CIK 0001288859 · Director · President & CEO 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 111,864 Underlying: Common Stock · 111,864 shares Expires 2036-03-14 F5 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:11 UTC |
Blum Robert IDirector · President & CEO
|
GrantIncentive Stock Option (Right to Buy) · Derivative | 1,665 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000024 · form4.xml · derivative · entry 4 Blum Robert I · CIK 0001288859 · Director · President & CEO 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,665 Underlying: Common Stock · 1,665 shares Expires 2036-03-14 F4 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:11 UTC |
Blum Robert IDirector · President & CEO
|
GrantCommon Stock | 75,258 | $0.00 | $0.00 |
DisclosureSEC source: 0001061983-26-000024 · form4.xml · nonDerivative · entry 1 Blum Robert I · CIK 0001288859 · Director · President & CEO 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 466,931 F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:08 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
GrantNon-Qualified Stock Option (Right to Buy) · Derivative | 29,480 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000023 · form4.xml · derivative · entry 4 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 29,480 Underlying: Common Stock · 29,480 shares Expires 2036-03-14 F4 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:08 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
GrantIncentive Stock Option (Right to Buy) · Derivative | 1,665 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000023 · form4.xml · derivative · entry 3 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,665 Underlying: Common Stock · 1,665 shares Expires 2036-03-14 F3 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:08 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
GrantCommon Stock | 13,320 | $0.00 | $0.00 |
DisclosureSEC source: 0001061983-26-000023 · form4.xml · nonDerivative · entry 2 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 81,824 F2 · kind: Special supplemental equity award comprised of restricted stock units ("RSUs" that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 50% of the RSUs on the 1-year anniversary of the grant date and 50% of the RSUs on the 2-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:08 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
GrantCommon Stock | 20,646 | $0.00 | $0.00 |
DisclosureSEC source: 0001061983-26-000023 · form4.xml · nonDerivative · entry 1 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 68,504 F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:06 UTC |
Hessekiel JeffreyChief Legal & Admin Officer
|
GrantNon-Qualified Stock Option (Right to Buy) · Derivative | 22,820 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000022 · form4.xml · derivative · entry 3 Hessekiel Jeffrey · CIK 0001599803 · Chief Legal & Admin Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 22,820 Underlying: Common Stock · 22,820 shares Expires 2036-03-14 F3 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:06 UTC |
Hessekiel JeffreyChief Legal & Admin Officer
|
GrantIncentive Stock Option (Right to Buy) · Derivative | 8,325 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000022 · form4.xml · derivative · entry 2 Hessekiel Jeffrey · CIK 0001599803 · Chief Legal & Admin Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 8,325 Underlying: Common Stock · 8,325 shares Expires 2036-03-14 F2 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:06 UTC |
Hessekiel JeffreyChief Legal & Admin Officer
|
GrantCommon Stock | 20,646 | $0.00 | $0.00 |
DisclosureSEC source: 0001061983-26-000022 · form4.xml · nonDerivative · entry 1 Hessekiel Jeffrey · CIK 0001599803 · Chief Legal & Admin Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 107,943 F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:03 UTC |
Malik Fady IbrahamEVP Research & Development
|
GrantNon-Qualified Stock Option (Right to Buy) · Derivative | 39,527 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000020 · form4.xml · derivative · entry 3 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 39,527 Underlying: Common Stock · 39,527 shares Expires 2036-03-14 F3 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:03 UTC |
Malik Fady IbrahamEVP Research & Development
|
GrantIncentive Stock Option (Right to Buy) · Derivative | 1,665 | $0.00 Strike: $60.06 | $0.00 |
DisclosureSEC source: 0001061983-26-000020 · form4.xml · derivative · entry 2 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 1,665 Underlying: Common Stock · 1,665 shares Expires 2036-03-14 F2 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 15, 2026 Filed Mar 17, 2026 20:03 UTC |
Malik Fady IbrahamEVP Research & Development
|
GrantCommon Stock | 27,306 | $0.00 | $0.00 |
DisclosureSEC source: 0001061983-26-000020 · form4.xml · nonDerivative · entry 1 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 165,935 F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan. Read SEC document |
| March 09, 2026 Filed Mar 10, 2026 22:05 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 2,582 | $60.72 | $156,779.04 |
DisclosureSEC source: 0001061983-26-000018 · form4.xml · nonDerivative · entry 1 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 47,858 F1 · kind: Sell to cover transaction to satisfy company tax withholding obligations upon vesting of RSUs. Read SEC document |
| March 09, 2026 Filed Mar 10, 2026 22:03 UTC |
Malik Fady IbrahamEVP Research & Development
|
SaleCommon Stock | 2,907 | $60.72 | $176,513.04 |
DisclosureSEC source: 0001061983-26-000017 · form4.xml · nonDerivative · entry 1 Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 138,629 F1 · kind: Sell to cover transaction to satisfy company tax withholding obligations upon vesting of RSUs. Read SEC document |
| March 09, 2026 Filed Mar 10, 2026 22:00 UTC |
Blum Robert IDirector · President & CEO
|
SaleCommon Stock | 7,931 | $60.72 | $481,570.32 |
DisclosureSEC source: 0001061983-26-000016 · form4.xml · nonDerivative · entry 1 Blum Robert I · CIK 0001288859 · Director · President & CEO 10b5-1 filing: No plan indicated Ownership: Direct Disclosed balance after: 391,673 F1 · kind: Sell to cover transaction to satisfy company tax withholding obligations upon vesting of RSUs. Read SEC document |
| March 05, 2026 Filed Mar 5, 2026 21:27 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
Exercise / conversionNon-Qualified Stock Option (Right to Buy) · Derivative | 15,000 | $0.00 Strike: $23.26 | $0.00 |
DisclosureSEC source: 0001061983-26-000015 · form4.xml · derivative · entry 6 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 69,000 Underlying: Common Stock · 15,000 shares Expires 2031-03-31 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. F1 · derivative.exercise_date: Stock options will vest over 4 years from the date of the grant, with 1/4th of the shares underlying the reporting person's option vesting on the one-year anniversary of the grant date and the remaining shares thereafter vesting monthly at a rate of 1/48th of the shares underlying the reporting person's option over the subsequent 36 months, subject to the reporting person's continued employment with the Issuer. Read SEC document |
| March 05, 2026 Filed Mar 5, 2026 21:27 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
Exercise / conversionNon-Qualified Stock Option (Right to Buy) · Derivative | 11,000 | $0.00 Strike: $39.13 | $0.00 |
DisclosureSEC source: 0001061983-26-000015 · form4.xml · derivative · entry 5 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 24,403 Underlying: Common Stock · 11,000 shares Expires 2033-03-06 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| March 05, 2026 Filed Mar 5, 2026 21:27 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
Exercise / conversionCommon Stock | 15,000 | $23.26 | $348,900.00 |
DisclosureSEC source: 0001061983-26-000015 · form4.xml · nonDerivative · entry 4 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 65,440 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
| March 05, 2026 Filed Mar 5, 2026 21:27 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 11,000 | $61.88 | $680,680.00 |
DisclosureSEC source: 0001061983-26-000015 · form4.xml · nonDerivative · entry 3 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 50,440 Read SEC document |
| March 05, 2026 Filed Mar 5, 2026 21:27 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
SaleCommon Stock | 15,000 | $61.87 | $928,050.00 |
DisclosureSEC source: 0001061983-26-000015 · form4.xml · nonDerivative · entry 2 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 61,440 Read SEC document |
| March 05, 2026 Filed Mar 5, 2026 21:27 UTC |
Callos AndrewEVP, Chief Commercial Officer
|
Exercise / conversionCommon Stock | 11,000 | $39.13 | $430,430.00 |
DisclosureSEC source: 0001061983-26-000015 · form4.xml · nonDerivative · entry 1 Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer 10b5-1 filing: Plan reported Ownership: Direct Disclosed balance after: 76,440 Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event. Read SEC document |
Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.