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Nasdaq · USD

CYTK

CYTOKINETICS INC

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Tapewire entity
3528
SEC CIK
0001061983
Parsed reports
875

Last 12 months

Inside the activity.

0 purchase rows · 83 sale rows

Disclosed non-derivative P/S rows, by transaction month. Includes amendments and private transactions.
Monthly counts
MonthPurchasesSales
Nov 202504
Dec 202509
Jan 202603
Feb 202602
Mar 2026017
Apr 202608
May 202609
Jun 202608
Jul 202609
Aug 202604
Sep 202608
Oct 202602

Latest available

Insider transactions

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Purchases/sales include open-market and private transactions. Plan disclosure applies to the filing; individual rows may differ. “Not disclosed” is not “unplanned.”

The cutoff filters transaction history only. Company summaries and owner relationships show the latest available disclosures. Parser corrections can improve historical records.

Transaction dateOwner / reported roleActivity / securityShares / unitsReported priceReported valueDetails
April 15, 2026 Filed Apr 15, 2026 22:37 UTC GrantCommon Stock 95 $65.37 $6,210.15
Disclosure

SEC source: 0001061983-26-000042 · form4.xml · nonDerivative · entry 1

Wysenski Nancy · CIK 0001294596 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 31,066

F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:35 UTC GrantCommon Stock 191 $65.37 $12,485.67
Disclosure

SEC source: 0001061983-26-000040 · form4.xml · nonDerivative · entry 1

Kaye Edward M. MD · CIK 0001522780 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 10,365

F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:36 UTC GrantCommon Stock 95 $65.37 $6,210.15
Disclosure

SEC source: 0001061983-26-000041 · form4.xml · nonDerivative · entry 1

WIERENGA WENDELL · CIK 0001239956 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 32,637

F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:34 UTC GrantCommon Stock 325 $65.37 $21,245.25
Disclosure

SEC source: 0001061983-26-000039 · form4.xml · nonDerivative · entry 1

HENDERSON JOHN T · CIK 0001226488 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 75,237

F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:33 UTC GrantCommon Stock 191 $65.37 $12,485.67
Disclosure

SEC source: 0001061983-26-000038 · form4.xml · nonDerivative · entry 1

Harrington Robert Arthur · CIK 0001923988 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,930

F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 21:27 UTC
Blum Robert IDirector · President & CEO
SaleCommon Stock 7,500 $65.38 $490,350.00
Disclosure

SEC source: 0001061983-26-000035 · form4.xml · nonDerivative · entry 1

Blum Robert I · CIK 0001288859 · Director · President & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 415,330

Read SEC document
April 15, 2026 Filed Apr 15, 2026 22:32 UTC
Daly James MDirector
GrantCommon Stock 191 $65.37 $12,485.67
Disclosure

SEC source: 0001061983-26-000037 · form4.xml · nonDerivative · entry 1

Daly James M · CIK 0001560782 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 388

F1 · kind: Shares of common stock granted pursuant to Director Equity in Lieu of Cash Retainer Program. Shares are fully vested.

Read SEC document
April 15, 2026 Filed Apr 15, 2026 21:29 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 7,449 $66.02 $491,782.98
Disclosure

SEC source: 0001061983-26-000036 · form4.xml · nonDerivative · entry 1

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 58,555

Read SEC document
April 07, 2026 Filed Apr 8, 2026 20:18 UTC
Malik Fady IbrahamEVP Research & Development
Exercise / conversionNon-Qualified Stock Option (Right to Buy) · Derivative 1,000 $0.00 Strike: $10.60 $0.00
Disclosure

SEC source: 0001061983-26-000034 · form4.xml · derivative · entry 6

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,000 shares

Expires 2027-02-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 07, 2026 Filed Apr 8, 2026 20:18 UTC
Malik Fady IbrahamEVP Research & Development
Exercise / conversionNon-Qualified Stock Option (Right to Buy) · Derivative 3,500 $0.00 Strike: $7.80 $0.00
Disclosure

SEC source: 0001061983-26-000034 · form4.xml · derivative · entry 5

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 58,386

Underlying: Common Stock · 3,500 shares

Expires 2028-02-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 07, 2026 Filed Apr 8, 2026 20:18 UTC
Malik Fady IbrahamEVP Research & Development
SaleCommon Stock 1,000 $64.75 $64,750.00
Disclosure

SEC source: 0001061983-26-000034 · form4.xml · nonDerivative · entry 4

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 153,902

Read SEC document
April 07, 2026 Filed Apr 8, 2026 20:18 UTC
Malik Fady IbrahamEVP Research & Development
Exercise / conversionCommon Stock 1,000 $10.60 $10,600.00
Disclosure

SEC source: 0001061983-26-000034 · form4.xml · nonDerivative · entry 3

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 154,902

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 07, 2026 Filed Apr 8, 2026 20:18 UTC
Malik Fady IbrahamEVP Research & Development
SaleCommon Stock 3,500 $65.21 $228,235.00
Disclosure

SEC source: 0001061983-26-000034 · form4.xml · nonDerivative · entry 2

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 153,902

Read SEC document
April 07, 2026 Filed Apr 8, 2026 20:18 UTC
Malik Fady IbrahamEVP Research & Development
Exercise / conversionCommon Stock 3,500 $7.80 $27,300.00
Disclosure

SEC source: 0001061983-26-000034 · form4.xml · nonDerivative · entry 1

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 157,402

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
April 01, 2026 Filed Apr 1, 2026 20:34 UTC
Blum Robert IDirector · President & CEO
SaleCommon Stock 7,500 $66.63 $499,725.00
Disclosure

SEC source: 0001061983-26-000031 · form4.xml · nonDerivative · entry 1

Blum Robert I · CIK 0001288859 · Director · President & CEO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 422,830

Read SEC document
March 31, 2026 Filed Mar 31, 2026 20:21 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 3,639 $65.00 $236,535.00
Disclosure

SEC source: 0001061983-26-000030 · form4.xml · nonDerivative · entry 1

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 66,004

Read SEC document
March 18, 2026 Filed Mar 18, 2026 20:55 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 1,930 $62.07 $119,795.10
Disclosure

SEC source: 0001061983-26-000025 · form4.xml · nonDerivative · entry 1

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 78,185

Read SEC document
March 17, 2026 Filed Mar 18, 2026 21:46 UTC
Lee SungEVP, Chief Financial Officer
SaleCommon Stock 4,935 $62.15 $306,710.25
Disclosure

SEC source: 0001061983-26-000029 · form4.xml · nonDerivative · entry 1

Lee Sung · CIK 0001793200 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 87,127

F1 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting.

Read SEC document
March 17, 2026 Filed Mar 18, 2026 21:43 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 2,916 $62.15 $181,229.40
Disclosure

SEC source: 0001061983-26-000028 · form4.xml · nonDerivative · entry 2

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 71,573

F2 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting.

Read SEC document
March 17, 2026 Filed Mar 18, 2026 21:43 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 5,626 $62.15 $349,655.90
Disclosure

SEC source: 0001061983-26-000028 · form4.xml · nonDerivative · entry 1

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 74,489

F1 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting.

Read SEC document
March 17, 2026 Filed Mar 18, 2026 21:40 UTC
Malik Fady IbrahamEVP Research & Development
SaleCommon Stock 4,397 $62.15 $273,273.55
Disclosure

SEC source: 0001061983-26-000027 · form4.xml · nonDerivative · entry 2

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,902

F2 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting.

Read SEC document
March 17, 2026 Filed Mar 18, 2026 21:40 UTC
Malik Fady IbrahamEVP Research & Development
SaleCommon Stock 7,636 $62.15 $474,577.40
Disclosure

SEC source: 0001061983-26-000027 · form4.xml · nonDerivative · entry 1

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 158,299

F1 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting.

Read SEC document
March 17, 2026 Filed Mar 18, 2026 21:37 UTC
Blum Robert IDirector · President & CEO
SaleCommon Stock 23,928 $62.15 $1,487,125.20
Disclosure

SEC source: 0001061983-26-000026 · form4.xml · nonDerivative · entry 2

Blum Robert I · CIK 0001288859 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 430,330

F2 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting.

Read SEC document
March 17, 2026 Filed Mar 18, 2026 21:37 UTC
Blum Robert IDirector · President & CEO
SaleCommon Stock 12,673 $62.15 $787,626.95
Disclosure

SEC source: 0001061983-26-000026 · form4.xml · nonDerivative · entry 1

Blum Robert I · CIK 0001288859 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 454,258

F1 · kind: Company compelled sell-to-cover transaction to satisfy tax withholding obligations attributable to RSU vesting.

Read SEC document
March 16, 2026 Filed Mar 16, 2026 21:14 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 1,709 $61.03 $104,300.27
Disclosure

SEC source: 0001061983-26-000019 · form4.xml · nonDerivative · entry 1

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 46,149

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:05 UTC
Lee SungEVP, Chief Financial Officer
GrantNon-Qualified Stock Option (Right to Buy) · Derivative 29,480 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000021 · form4.xml · derivative · entry 3

Lee Sung · CIK 0001793200 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,480

Underlying: Common Stock · 29,480 shares

Expires 2036-03-14

F3 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:05 UTC
Lee SungEVP, Chief Financial Officer
GrantIncentive Stock Option (Right to Buy) · Derivative 1,665 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000021 · form4.xml · derivative · entry 2

Lee Sung · CIK 0001793200 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,665

Underlying: Common Stock · 1,665 shares

Expires 2036-03-14

F2 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:05 UTC
Lee SungEVP, Chief Financial Officer
GrantCommon Stock 20,646 $0.00 $0.00
Disclosure

SEC source: 0001061983-26-000021 · form4.xml · nonDerivative · entry 1

Lee Sung · CIK 0001793200 · EVP, Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 92,062

F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:11 UTC
Blum Robert IDirector · President & CEO
GrantNon-Qualified Stock Option (Right to Buy) · Derivative 111,864 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000024 · form4.xml · derivative · entry 5

Blum Robert I · CIK 0001288859 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 111,864

Underlying: Common Stock · 111,864 shares

Expires 2036-03-14

F5 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:11 UTC
Blum Robert IDirector · President & CEO
GrantIncentive Stock Option (Right to Buy) · Derivative 1,665 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000024 · form4.xml · derivative · entry 4

Blum Robert I · CIK 0001288859 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,665

Underlying: Common Stock · 1,665 shares

Expires 2036-03-14

F4 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:11 UTC
Blum Robert IDirector · President & CEO
GrantCommon Stock 75,258 $0.00 $0.00
Disclosure

SEC source: 0001061983-26-000024 · form4.xml · nonDerivative · entry 1

Blum Robert I · CIK 0001288859 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 466,931

F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:08 UTC
Callos AndrewEVP, Chief Commercial Officer
GrantNon-Qualified Stock Option (Right to Buy) · Derivative 29,480 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000023 · form4.xml · derivative · entry 4

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,480

Underlying: Common Stock · 29,480 shares

Expires 2036-03-14

F4 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:08 UTC
Callos AndrewEVP, Chief Commercial Officer
GrantIncentive Stock Option (Right to Buy) · Derivative 1,665 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000023 · form4.xml · derivative · entry 3

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,665

Underlying: Common Stock · 1,665 shares

Expires 2036-03-14

F3 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:08 UTC
Callos AndrewEVP, Chief Commercial Officer
GrantCommon Stock 13,320 $0.00 $0.00
Disclosure

SEC source: 0001061983-26-000023 · form4.xml · nonDerivative · entry 2

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 81,824

F2 · kind: Special supplemental equity award comprised of restricted stock units ("RSUs" that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 50% of the RSUs on the 1-year anniversary of the grant date and 50% of the RSUs on the 2-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:08 UTC
Callos AndrewEVP, Chief Commercial Officer
GrantCommon Stock 20,646 $0.00 $0.00
Disclosure

SEC source: 0001061983-26-000023 · form4.xml · nonDerivative · entry 1

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 68,504

F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:06 UTC
Hessekiel JeffreyChief Legal & Admin Officer
GrantNon-Qualified Stock Option (Right to Buy) · Derivative 22,820 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000022 · form4.xml · derivative · entry 3

Hessekiel Jeffrey · CIK 0001599803 · Chief Legal & Admin Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 22,820

Underlying: Common Stock · 22,820 shares

Expires 2036-03-14

F3 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:06 UTC
Hessekiel JeffreyChief Legal & Admin Officer
GrantIncentive Stock Option (Right to Buy) · Derivative 8,325 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000022 · form4.xml · derivative · entry 2

Hessekiel Jeffrey · CIK 0001599803 · Chief Legal & Admin Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,325

Underlying: Common Stock · 8,325 shares

Expires 2036-03-14

F2 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:06 UTC
Hessekiel JeffreyChief Legal & Admin Officer
GrantCommon Stock 20,646 $0.00 $0.00
Disclosure

SEC source: 0001061983-26-000022 · form4.xml · nonDerivative · entry 1

Hessekiel Jeffrey · CIK 0001599803 · Chief Legal & Admin Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 107,943

F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:03 UTC
Malik Fady IbrahamEVP Research & Development
GrantNon-Qualified Stock Option (Right to Buy) · Derivative 39,527 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000020 · form4.xml · derivative · entry 3

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,527

Underlying: Common Stock · 39,527 shares

Expires 2036-03-14

F3 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:03 UTC
Malik Fady IbrahamEVP Research & Development
GrantIncentive Stock Option (Right to Buy) · Derivative 1,665 $0.00 Strike: $60.06 $0.00
Disclosure

SEC source: 0001061983-26-000020 · form4.xml · derivative · entry 2

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 1,665

Underlying: Common Stock · 1,665 shares

Expires 2036-03-14

F2 · kind: Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 15, 2026 Filed Mar 17, 2026 20:03 UTC
Malik Fady IbrahamEVP Research & Development
GrantCommon Stock 27,306 $0.00 $0.00
Disclosure

SEC source: 0001061983-26-000020 · form4.xml · nonDerivative · entry 1

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 165,935

F1 · kind: Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan.

Read SEC document
March 09, 2026 Filed Mar 10, 2026 22:05 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 2,582 $60.72 $156,779.04
Disclosure

SEC source: 0001061983-26-000018 · form4.xml · nonDerivative · entry 1

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 47,858

F1 · kind: Sell to cover transaction to satisfy company tax withholding obligations upon vesting of RSUs.

Read SEC document
March 09, 2026 Filed Mar 10, 2026 22:03 UTC
Malik Fady IbrahamEVP Research & Development
SaleCommon Stock 2,907 $60.72 $176,513.04
Disclosure

SEC source: 0001061983-26-000017 · form4.xml · nonDerivative · entry 1

Malik Fady Ibraham · CIK 0001551778 · EVP Research & Development

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 138,629

F1 · kind: Sell to cover transaction to satisfy company tax withholding obligations upon vesting of RSUs.

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March 09, 2026 Filed Mar 10, 2026 22:00 UTC
Blum Robert IDirector · President & CEO
SaleCommon Stock 7,931 $60.72 $481,570.32
Disclosure

SEC source: 0001061983-26-000016 · form4.xml · nonDerivative · entry 1

Blum Robert I · CIK 0001288859 · Director · President & CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 391,673

F1 · kind: Sell to cover transaction to satisfy company tax withholding obligations upon vesting of RSUs.

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March 05, 2026 Filed Mar 5, 2026 21:27 UTC
Callos AndrewEVP, Chief Commercial Officer
Exercise / conversionNon-Qualified Stock Option (Right to Buy) · Derivative 15,000 $0.00 Strike: $23.26 $0.00
Disclosure

SEC source: 0001061983-26-000015 · form4.xml · derivative · entry 6

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,000

Underlying: Common Stock · 15,000 shares

Expires 2031-03-31

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: Stock options will vest over 4 years from the date of the grant, with 1/4th of the shares underlying the reporting person's option vesting on the one-year anniversary of the grant date and the remaining shares thereafter vesting monthly at a rate of 1/48th of the shares underlying the reporting person's option over the subsequent 36 months, subject to the reporting person's continued employment with the Issuer.

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March 05, 2026 Filed Mar 5, 2026 21:27 UTC
Callos AndrewEVP, Chief Commercial Officer
Exercise / conversionNon-Qualified Stock Option (Right to Buy) · Derivative 11,000 $0.00 Strike: $39.13 $0.00
Disclosure

SEC source: 0001061983-26-000015 · form4.xml · derivative · entry 5

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 24,403

Underlying: Common Stock · 11,000 shares

Expires 2033-03-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:27 UTC
Callos AndrewEVP, Chief Commercial Officer
Exercise / conversionCommon Stock 15,000 $23.26 $348,900.00
Disclosure

SEC source: 0001061983-26-000015 · form4.xml · nonDerivative · entry 4

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 65,440

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:27 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 11,000 $61.88 $680,680.00
Disclosure

SEC source: 0001061983-26-000015 · form4.xml · nonDerivative · entry 3

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 50,440

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:27 UTC
Callos AndrewEVP, Chief Commercial Officer
SaleCommon Stock 15,000 $61.87 $928,050.00
Disclosure

SEC source: 0001061983-26-000015 · form4.xml · nonDerivative · entry 2

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 61,440

Read SEC document
March 05, 2026 Filed Mar 5, 2026 21:27 UTC
Callos AndrewEVP, Chief Commercial Officer
Exercise / conversionCommon Stock 11,000 $39.13 $430,430.00
Disclosure

SEC source: 0001061983-26-000015 · form4.xml · nonDerivative · entry 1

Callos Andrew · CIK 0001852129 · EVP, Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 76,440

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

Read SEC document

Value uses the disclosed total when available, otherwise shares × reported transaction price. It is not an estimate of exercise cash cost or investment performance.