CRBU

SEC source: 0001917391-24-000009 · wk-form4_1724184417.xml · derivative · entry 1

Albertson Tina M. · CIK 0001917391 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,000

Underlying: Common Stock · 300,000 shares

Expires 2034-08-18

F1 · derivative.exercise_date: 25% of the options will vest upon the one-year anniversary of the grant date, August 19, 2025, and 1/48th will vest monthly thereafter over the 36-month period following the one-year cliff, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001628280-24-006412 · wk-form4_1708639705.xml · derivative · entry 1

Sacks Natalie · CIK 0001683811 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,500

Underlying: Common Stock · 39,500 shares

Expires 2034-02-19

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 20, 2025, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001628280-24-006416 · wk-form4_1708639949.xml · derivative · entry 1

Zheng Ran · CIK 0001885914 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,500

Underlying: Common Stock · 39,500 shares

Expires 2034-02-19

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 20, 2025, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001628280-24-006421 · wk-form4_1708640281.xml · derivative · entry 3

Haurwitz Rachel E. · CIK 0001670579 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 546,950

Underlying: Common Stock · 546,950 shares

Expires 2034-02-19

F3 · derivative.exercise_date: 25% of the options will vest upon the one-year anniversary of the grant date, February 20, 2025, and 1/48th will vest monthly thereafter over the 36-month period following the one-year cliff, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001628280-24-006421 · wk-form4_1708640281.xml · nonDerivative · entry 1

Haurwitz Rachel E. · CIK 0001670579 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 158,700

F1 · shares: This reflects restricted stock units ("RSUs") that vest in four equal annual installments beginning on February 20, 2025, subject to the reporting person's continued services to the Issuer through the applicable vesting dates. The RSUs will be settled in stock within 30 days after each vesting date.

SEC source: 0001628280-24-006402 · wk-form4_1708638851.xml · derivative · entry 1

Braunstein Scott · CIK 0001643875 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,500

Underlying: Common Stock · 39,500 shares

Expires 2034-02-19

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 20, 2025, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001628280-24-006429 · wk-form4_1708640636.xml · derivative · entry 2

MCCLUNG BARBARA G · CIK 0001231321 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,000

Underlying: Common Stock · 153,000 shares

Expires 2034-02-19

F2 · derivative.exercise_date: 25% of the options will vest upon the one-year anniversary of the grant date, February 20, 2025, and 1/48th will vest monthly thereafter over the 36-month period following the one-year cliff, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001628280-24-006429 · wk-form4_1708640636.xml · nonDerivative · entry 1

MCCLUNG BARBARA G · CIK 0001231321 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 409,566

F1 · shares: This reflects restricted stock units ("RSUs") that vest in four equal annual installments beginning on February 20, 2025, subject to the reporting person's continued services to the Issuer through the applicable vesting dates. The RSUs will be settled in stock within 30 days after each vesting date.

SEC source: 0001628280-24-006405 · wk-form4_1708639013.xml · derivative · entry 1

GUGGENHIME ANDREW · CIK 0001230724 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,500

Underlying: Common Stock · 39,500 shares

Expires 2034-02-19

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 20, 2025, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001628280-24-006433 · wk-form4_1708640897.xml · derivative · entry 2

O'Byrne Jason · CIK 0001871145 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,000

Underlying: Common Stock · 153,000 shares

Expires 2034-02-19

F3 · derivative.exercise_date: 25% of the options will vest upon the one-year anniversary of the grant date, February 20, 2025, and 1/48th will vest monthly thereafter over the 36-month period following the one-year cliff, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001628280-24-006433 · wk-form4_1708640897.xml · nonDerivative · entry 1

O'Byrne Jason · CIK 0001871145 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,224

F1 · shares: This reflects restricted stock units ("RSUs") that vest in four equal annual installments beginning on February 20, 2025, subject to the reporting person's continued services to the Issuer through the applicable vesting dates. The RSUs will be settled in stock within 30 days after each vesting date.

F2 · balance_after: Includes 1,888 shares purchased pursuant to the Issuer's 2021 Employee Stock Purchase Plan on February 15, 2022 for $9.85 per share.

SEC source: 0001628280-24-006425 · wk-form4_1708640476.xml · derivative · entry 2

Khan Ruhi Ahmad · CIK 0001891113 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,000

Underlying: Common Stock · 153,000 shares

Expires 2034-02-19

F2 · derivative.exercise_date: 25% of the options will vest upon the one-year anniversary of the grant date, February 20, 2025, and 1/48th will vest monthly thereafter over the 36-month period following the one-year cliff, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001628280-24-006425 · wk-form4_1708640476.xml · nonDerivative · entry 1

Khan Ruhi Ahmad · CIK 0001891113 · Chief Business Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 33,000

F1 · shares: This reflects restricted stock units ("RSUs") that vest in four equal annual installments beginning on February 20, 2025, subject to the reporting person's continued services to the Issuer through the applicable vesting dates. The RSUs will be settled in stock within 30 days after each vesting date.

SEC source: 0001628280-24-006419 · wk-form4_1708640094.xml · derivative · entry 2

Kanner Steven · CIK 0001871131 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 153,000

Underlying: Common Stock · 153,000 shares

Expires 2034-02-19

F2 · derivative.exercise_date: 25% of the options will vest upon the one-year anniversary of the grant date, February 20, 2025, and 1/48th will vest monthly thereafter over the 36-month period following the one-year cliff, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001628280-24-006419 · wk-form4_1708640094.xml · nonDerivative · entry 1

Kanner Steven · CIK 0001871131 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 387,037

F1 · shares: This reflects restricted stock units ("RSUs") that vest in four equal annual installments beginning on February 20, 2025, subject to the reporting person's continued services to the Issuer through the applicable vesting dates. The RSUs will be settled in stock within 30 days after each vesting date.

SEC source: 0001628280-24-006414 · wk-form4_1708639829.xml · derivative · entry 1

Whiting Nancy · CIK 0001880609 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,500

Underlying: Common Stock · 39,500 shares

Expires 2034-02-19

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 20, 2025, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001628280-24-006411 · wk-form4_1708639530.xml · derivative · entry 1

Richardson-Heron Dara · CIK 0001893193 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,500

Underlying: Common Stock · 39,500 shares

Expires 2034-02-19

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 20, 2025, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001628280-24-006407 · wk-form4_1708639272.xml · derivative · entry 1

JOHNSON DAVID LEE · CIK 0001733883 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,500

Underlying: Common Stock · 39,500 shares

Expires 2034-02-19

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 20, 2025, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001871131-24-000002 · wk-form4_1707429995.xml · derivative · entry 2

Kanner Steven · CIK 0001871131 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,623

Underlying: Common Stock · 30,577 shares

Expires 2029-09-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: 1/4th of the shares subject to this option vested on October 1, 2020 and an additional 1/48th of the aggregate number of shares subject to the option have vested or will vest on the corresponding day of each month thereafter, subject to the reporting person's continued services to the Issuer through the applicable vesting dates.

SEC source: 0001871131-24-000002 · wk-form4_1707429995.xml · nonDerivative · entry 1

Kanner Steven · CIK 0001871131 · Chief Scientific Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 354,037

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001754067-24-000006 · wk-form4_1704834615.xml · derivative · entry 1

Kelly Timothy P · CIK 0001754067 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,000

Underlying: Common Stock · 300,000 shares

Expires 2034-01-07

F1 · derivative.exercise_date: 25% of the shares subject to the option shall vest on January 1, 2025, and the remaining shares subject to the option shall vest monthly thereafter (1/48 of the shares per month for the 36 months following the one-year cliff), subject to the Reporting Person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-23-000073 · wk-form4_1686342698.xml · derivative · entry 3

Haurwitz Rachel E. · CIK 0001670579 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 96,350

Underlying: Common Stock · 10,000 shares

Expires 2023-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 1/4th of the shares subject to this option vested on June 12, 2019 and an additional 1/48th of the aggregate number of shares subject to the option vested on the corresponding day of each month thereafter until the option became fully vested on June 12, 2022.

SEC source: 0001619856-23-000073 · wk-form4_1686342698.xml · nonDerivative · entry 1

Haurwitz Rachel E. · CIK 0001670579 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 40,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001619856-23-000039 · wf-form4_167951616420908.xml · derivative · entry 3

Haurwitz Rachel E. · CIK 0001670579 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 106,350

Underlying: Common Stock · 10,000 shares

Expires 2023-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 1/4th of the shares subject to this option vested on June 12, 2019 and an additional 1/48th of the aggregate number of shares subject to the option vested on the corresponding day of each month thereafter until the option became fully vested on June 12, 2022.

SEC source: 0001619856-23-000039 · wf-form4_167951616420908.xml · nonDerivative · entry 1

Haurwitz Rachel E. · CIK 0001670579 · Director · President and CEO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 30,000

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001619856-23-000024 · wf-form4_167719030244436.xml · derivative · entry 1

Sacks Natalie · CIK 0001683811 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,500

Underlying: Common Stock · 21,500 shares

Expires 2033-02-20

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 21, 2024, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001619856-23-000019 · wf-form4_167719010634615.xml · derivative · entry 1

Zheng Ran · CIK 0001885914 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,500

Underlying: Common Stock · 21,500 shares

Expires 2033-02-20

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 21, 2024, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001619856-23-000028 · wf-form4_167719043346430.xml · derivative · entry 1

Haurwitz Rachel E. · CIK 0001670579 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 510,500

Underlying: Common Stock · 510,500 shares

Expires 2033-02-20

F1 · derivative.exercise_date: The shares subject to this option will vest in equal monthly installments starting on the first monthly anniversary of the grant date until the option is fully vested on February 21, 2027, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-23-000023 · wf-form4_167719023966401.xml · derivative · entry 1

Braunstein Scott · CIK 0001643875 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,500

Underlying: Common Stock · 21,500 shares

Expires 2033-02-20

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 21, 2024, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001619856-23-000021 · wf-form4_167719018333486.xml · derivative · entry 1

MCCLUNG BARBARA G · CIK 0001231321 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,000

Underlying: Common Stock · 131,000 shares

Expires 2033-02-20

F1 · derivative.exercise_date: The shares subject to this option will vest in equal monthly installments starting on the first monthly anniversary of the grant date until the option is fully vested on February 21, 2027, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-23-000022 · wf-form4_167719020813142.xml · derivative · entry 1

GUGGENHIME ANDREW · CIK 0001230724 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,500

Underlying: Common Stock · 21,500 shares

Expires 2033-02-20

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 21, 2024, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001619856-23-000027 · wf-form4_167719039206421.xml · derivative · entry 1

Kanner Steven · CIK 0001871131 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,000

Underlying: Common Stock · 131,000 shares

Expires 2033-02-20

F1 · derivative.exercise_date: The shares subject to this option will vest in equal monthly installments starting on the first monthly anniversary of the grant date until the option is fully vested on February 21, 2027, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-23-000025 · wf-form4_167719032608820.xml · derivative · entry 1

Khan Ruhi Ahmad · CIK 0001891113 · Chief Business Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,000

Underlying: Common Stock · 131,000 shares

Expires 2033-02-20

F1 · derivative.exercise_date: The shares subject to this option will vest in equal monthly installments starting on the first monthly anniversary of the grant date until the option is fully vested on February 21, 2027, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-23-000026 · wf-form4_167719034786758.xml · derivative · entry 1

Richardson-Heron Dara · CIK 0001893193 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,500

Underlying: Common Stock · 21,500 shares

Expires 2033-02-20

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 21, 2024, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001619856-23-000020 · wf-form4_167719014984142.xml · derivative · entry 1

Rizvi Syed Ali-aamir · CIK 0001897621 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,000

Underlying: Common Stock · 131,000 shares

Expires 2033-02-20

F1 · derivative.exercise_date: The shares subject to this option will vest in equal monthly installments starting on the first monthly anniversary of the grant date until the option is fully vested on February 21, 2027, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-23-000018 · wf-form4_167718885507722.xml · derivative · entry 1

Whiting Nancy · CIK 0001880609 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,500

Underlying: Common Stock · 21,500 shares

Expires 2033-02-20

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 21, 2024, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001619856-23-000017 · wf-form4_167718882178453.xml · derivative · entry 1

O'Byrne Jason · CIK 0001871145 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 131,000

Underlying: Common Stock · 131,000 shares

Expires 2033-02-20

F1 · derivative.exercise_date: The shares subject to this option will vest in equal monthly installments starting on the first monthly anniversary of the grant date until the option is fully vested on February 21, 2027, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-23-000016 · wf-form4_167718878109697.xml · derivative · entry 1

JOHNSON DAVID LEE · CIK 0001733883 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,500

Underlying: Common Stock · 21,500 shares

Expires 2033-02-20

F1 · derivative.exercise_date: One-twelfth of the shares subject to this option will vest on each monthly anniversary of the grant date such that the option will be fully vested on February 21, 2024, subject to the reporting person continuing to provide service to the Issuer through each such vesting date.

SEC source: 0001619856-23-000002 · wf-form4_167424918505378.xml · nonDerivative · entry 1

Rizvi Syed Ali-aamir · CIK 0001897621 · Chief Medical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 59,373

F1 · shares: Represents the number of shares sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units as provided in standing "sell to cover" instructions.

SEC source: 0001619856-22-000031 · wf-form4_167002566431978.xml · derivative · entry 2

Kanner Steven · CIK 0001871131 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 52,200

Underlying: Common Stock · 21,401 shares

Expires 2029-09-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: 1/4th of the shares subject to this option vested on October 1, 2020 and an additional 1/48th of the aggregate number of shares subject to the option have vested or will vest on the corresponding day of each month thereafter, subject to the reporting person's continued services to the Issuer through the applicable vesting dates.

SEC source: 0001619856-22-000031 · wf-form4_167002566431978.xml · nonDerivative · entry 1

Kanner Steven · CIK 0001871131 · Chief Scientific Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 323,460

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001619856-22-000003 · wf-form4_166517721515147.xml · derivative · entry 5

Fischesser Ryan · CIK 0001871155 · VP of Finance and Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,337

Underlying: Common Stock · 2,839 shares

Expires 2031-03-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 1/4th of the shares subject to this option vested on January 1, 2022 and an additional 1/48th of the aggregate number of shares subject to the option have vested or will vest on the corresponding day of each month thereafter until the option is fully vested on January 1, 2025, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-22-000003 · wf-form4_166517721515147.xml · derivative · entry 4

Fischesser Ryan · CIK 0001871155 · VP of Finance and Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 1,704

Underlying: Common Stock · 2,839 shares

Expires 2029-03-18

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: 1/4th of the shares subject to this option vested on January 1, 2020 and an additional 1/48th of the aggregate number of shares subject to the option have vested or will vest on the corresponding day of each month thereafter until the option is fully vested on January 1, 2023, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-22-000003 · wf-form4_166517721515147.xml · nonDerivative · entry 3

Fischesser Ryan · CIK 0001871155 · VP of Finance and Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 116,044

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · balance_after: Includes 4,848 shares represented by restricted stock units ("RSUs") that vest in two equal annual installments beginning on August 22, 2023, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-22-000003 · wf-form4_166517721515147.xml · nonDerivative · entry 2

Fischesser Ryan · CIK 0001871155 · VP of Finance and Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 113,205

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · balance_after: Includes 4,848 shares represented by restricted stock units ("RSUs") that vest in two equal annual installments beginning on August 22, 2023, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001619856-22-000003 · wf-form4_166517721515147.xml · nonDerivative · entry 1

Fischesser Ryan · CIK 0001871155 · VP of Finance and Controller

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 110,366

F1 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.67 to $10.94, inclusive. The reporting person undertakes to provide to Caribou Biosciences, Inc., any security holder of Caribou Biosciences, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote (1) to this Form 4.

F2 · balance_after: Includes 4,848 shares represented by restricted stock units ("RSUs") that vest in two equal annual installments beginning on August 22, 2023, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001209191-22-050315 · doc4.xml · derivative · entry 4

MCCLUNG BARBARA G · CIK 0001231321 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 47,318

Underlying: Common Stock · 27,518 shares

Expires 2029-09-30

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The shares subject to this option have vested or will vest in equal monthly installments until the option is fully vested on October 1, 2023, subject to the reporting person's continued service to the Issuer through the applicable vesting dates.

SEC source: 0001209191-22-050315 · doc4.xml · derivative · entry 3

MCCLUNG BARBARA G · CIK 0001231321 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 77 shares

Expires 2028-06-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The shares subject to this option vested in equal monthly installments until the option became fully vested on June 12, 2022.

SEC source: 0001209191-22-050315 · doc4.xml · nonDerivative · entry 2

MCCLUNG BARBARA G · CIK 0001231321 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 376,566

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-22-050315 · doc4.xml · nonDerivative · entry 1

MCCLUNG BARBARA G · CIK 0001231321 · Chief Legal Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 349,048

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.