BCAX

SEC source: 0001628280-26-015421 · wk-form4_1772755729.xml · nonDerivative · entry 4

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 148,318

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

SEC source: 0001628280-26-015419 · wk-form4_1772755592.xml · derivative · entry 6

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 52,913

Underlying: Common Stock · 16,300 shares

Expires 2023-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F3 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-015419 · wk-form4_1772755592.xml · nonDerivative · entry 4

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 55,286

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.45 to $18.72, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-015419 · wk-form4_1772755592.xml · nonDerivative · entry 3

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 71,586

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

SEC source: 0001628280-26-015778 · wk-form4_1772843254.xml · derivative · entry 7

Mazumdar Claire · CIK 0002034671 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 233,476

Underlying: Common Stock · 2,631 shares

Expires 2033-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F5 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-015778 · wk-form4_1772843254.xml · nonDerivative · entry 2

Mazumdar Claire · CIK 0002034671 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 339,392

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.73 to $18.77, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-015778 · wk-form4_1772843254.xml · nonDerivative · entry 1

Mazumdar Claire · CIK 0002034671 · Director · Chief Executive Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 342,023

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

SEC source: 0001628280-26-015423 · wk-form4_1772755827.xml · derivative · entry 4

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 125,334

Underlying: Common Stock · 12,892 shares

Expires 2033-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F3 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-015423 · wk-form4_1772755827.xml · nonDerivative · entry 3

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 205,141

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.00 to $18.32, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-015423 · wk-form4_1772755827.xml · nonDerivative · entry 2

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 209,641

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.00 to $18.32, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-015423 · wk-form4_1772755827.xml · nonDerivative · entry 1

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 222,533

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

SEC source: 0001628280-26-015421 · wk-form4_1772755729.xml · derivative · entry 7

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 82,747

Underlying: Common Stock · 6,237 shares

Expires 2033-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

F5 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-015421 · wk-form4_1772755729.xml · derivative · entry 6

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 58,144

Underlying: Common Stock · 7,318 shares

Expires 2033-04-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

F4 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following April 5, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-015421 · wk-form4_1772755729.xml · nonDerivative · entry 3

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 145,355

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.15 to $18.31, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-015421 · wk-form4_1772755729.xml · nonDerivative · entry 2

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 158,910

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

SEC source: 0001628280-26-015421 · wk-form4_1772755729.xml · nonDerivative · entry 1

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 152,673

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

SEC source: 0001628280-26-015419 · wk-form4_1772755592.xml · derivative · entry 5

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,213

Underlying: Common Stock · 200 shares

Expires 2023-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F3 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-015419 · wk-form4_1772755592.xml · nonDerivative · entry 2

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 55,286

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

SEC source: 0001628280-26-015419 · wk-form4_1772755592.xml · nonDerivative · entry 1

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 55,486

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

SEC source: 0001231919-26-000231 · form4-03022026_090351.xml · derivative · entry 3

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · Director · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · Director · 10% owner

RA Capital Nexus Fund III, L.P. · CIK 0001883840 · Director

Kolchinsky Peter · CIK 0001384859 · Director · 10% owner

Shah Rajeev M. · CIK 0001619841 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See Footnotes

Disclosed balance after: 2,200,000

Underlying: Common Stock · 2,200,000 shares

Expires not disclosed

F4 · derivative.exercise_date: The Pre-Funded Warrants have no expiration date and are exercisable at any time after the date of issuance. A holder of Pre-Funded Warrants may not exercise the Pre-Funded Warrant if the holder, together with its affiliates, would beneficially own more than 9.99% of the number of shares of common stock outstanding immediately after giving effect to such exercise.

F4 · derivative.expiration_date: The Pre-Funded Warrants have no expiration date and are exercisable at any time after the date of issuance. A holder of Pre-Funded Warrants may not exercise the Pre-Funded Warrant if the holder, together with its affiliates, would beneficially own more than 9.99% of the number of shares of common stock outstanding immediately after giving effect to such exercise.

F1 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund") and RA Capital Nexus Fund III, L.P. (the "Nexus Fund III"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. Each of the Adviser, the Adviser GP, the Fund, the Nexus Fund III, Dr. Kolchinsky and Mr. Shah disclaims beneficial ownership of any of the reported securities, except to the extent of its or his respective pecuniary interest therein.

F2 · ownership.nature: Held directly by the Fund.

SEC source: 0001231919-26-000231 · form4-03022026_090351.xml · nonDerivative · entry 1

RA CAPITAL MANAGEMENT, L.P. · CIK 0001346824 · Director · 10% owner

RA Capital Healthcare Fund LP · CIK 0001315082 · Director · 10% owner

RA Capital Nexus Fund III, L.P. · CIK 0001883840 · Director

Kolchinsky Peter · CIK 0001384859 · Director · 10% owner

Shah Rajeev M. · CIK 0001619841 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: No plan indicated

Ownership: Indirect · See footnotes

Disclosed balance after: 4,603,418

F1 · ownership.nature: RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund") and RA Capital Nexus Fund III, L.P. (the "Nexus Fund III"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. Each of the Adviser, the Adviser GP, the Fund, the Nexus Fund III, Dr. Kolchinsky and Mr. Shah disclaims beneficial ownership of any of the reported securities, except to the extent of its or his respective pecuniary interest therein.

F2 · ownership.nature: Held directly by the Fund.

SEC source: 0001628280-26-012823 · wk-form4_1772226833.xml · derivative · entry 4

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 138,226

Underlying: Common Stock · 3,108 shares

Expires 2033-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F3 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-012823 · wk-form4_1772226833.xml · nonDerivative · entry 3

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 209,641

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.00 to $18.14, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-012823 · wk-form4_1772226833.xml · nonDerivative · entry 2

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 210,164

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.00 to $18.14, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-012823 · wk-form4_1772226833.xml · nonDerivative · entry 1

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 213,272

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

SEC source: 0001628280-26-005474 · wk-form4_1770240841.xml · derivative · entry 1

Meisner Lara · CIK 0001883986 · Chief Legal Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,000

Underlying: Common Stock · 90,000 shares

Expires 2036-02-02

F1 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-005487 · wk-form4_1770241082.xml · derivative · entry 1

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 300,000

Underlying: Common Stock · 300,000 shares

Expires 2036-02-02

F1 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-005477 · wk-form4_1770240906.xml · derivative · entry 1

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 125,000

Underlying: Common Stock · 125,000 shares

Expires 2036-02-02

F1 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-005484 · wk-form4_1770241022.xml · derivative · entry 1

Mazumdar Claire · CIK 0002034671 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 450,000

Underlying: Common Stock · 450,000 shares

Expires 2036-02-02

F1 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-005479 · wk-form4_1770240967.xml · derivative · entry 1

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2036-02-02

F1 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following February 2, 2026, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-003419 · wk-form4_1769463288.xml · nonDerivative · entry 1

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 210,164

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.00 to $18.19, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-003418 · wk-form4_1769463219.xml · derivative · entry 3

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 65,462

Underlying: Common Stock · 1,882 shares

Expires 2033-04-05

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

F3 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following April 5, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-26-003418 · wk-form4_1769463219.xml · nonDerivative · entry 2

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 145,355

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.15 to $18.18, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0001628280-26-003418 · wk-form4_1769463219.xml · nonDerivative · entry 1

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 147,237

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

SEC source: 0001628280-26-002656 · wk-form4_1768945958.xml · nonDerivative · entry 1

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 213,992

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

SEC source: 0001628280-25-059045 · wk-form4_1767046687.xml · derivative · entry 2

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 39,909

Underlying: Common Stock · 25,000 shares

Expires 2032-10-04

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following October 4, 2022, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-25-059045 · wk-form4_1767046687.xml · nonDerivative · entry 1

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 214,141

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is an ISO exercise and hold to acquire and retain direct share ownership of the issuer.

SEC source: 0001628280-25-059035 · wk-form4_1767046215.xml · derivative · entry 2

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 98,987

Underlying: Common Stock · 19,789 shares

Expires 2033-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · derivative.exercise_date: 25% of the shares underlying this option vested on July 24, 2024, with the remainder vesting in twelve equal quarterly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0001628280-25-059035 · wk-form4_1767046215.xml · nonDerivative · entry 1

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 55,286

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This is an ISO exercise and hold to acquire and retain direct share ownership of the issuer.

SEC source: 0002034668-25-000012 · wk-form4_1766523739.xml · derivative · entry 3

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 88,984

Underlying: Common Stock · 9,200 shares

Expires 2033-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

F3 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0002034668-25-000012 · wk-form4_1766523739.xml · nonDerivative · entry 2

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 145,355

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.15 to $18.45, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0002034668-25-000012 · wk-form4_1766523739.xml · nonDerivative · entry 1

Hyep Ivan · CIK 0002034668 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 154,555

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.

SEC source: 0002034671-25-000012 · wk-form4_1766098974.xml · derivative · entry 2

Mazumdar Claire · CIK 0002034671 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 565,512

Underlying: Common Stock · 29,500 shares

Expires 2033-12-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following December 14, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0002034671-25-000012 · wk-form4_1766098974.xml · nonDerivative · entry 1

Mazumdar Claire · CIK 0002034671 · Director · Chief Executive Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 339,392

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0002034665-25-000011 · wk-form4_1765921919.xml · derivative · entry 4

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 141,334

Underlying: Common Stock · 8,000 shares

Expires 2033-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F3 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0002034665-25-000011 · wk-form4_1765921919.xml · nonDerivative · entry 3

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 189,141

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.55 to $18.88, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0002034665-25-000011 · wk-form4_1765921919.xml · nonDerivative · entry 2

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 193,641

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F2 · price: The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.55 to $18.88, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

SEC source: 0002034665-25-000011 · wk-form4_1765921919.xml · nonDerivative · entry 1

Cohlhepp Ryan · CIK 0002034665 · Director · President and COO

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 201,641

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

SEC source: 0002034679-25-000006 · wk-form4_1764113985.xml · derivative · entry 9

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 69,413

Underlying: Common Stock · 906 shares

Expires 2023-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F4 · derivative.exercise_date: The shares underlying this option vest in sixteen equal quarterly installments following August 8, 2023, subject to the Reporting Person's continued service on each such vesting date.

SEC source: 0002034679-25-000006 · wk-form4_1764113985.xml · derivative · entry 8

Raben David · CIK 0002034679 · Chief Medical Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 118,776

Underlying: Common Stock · 4,594 shares

Expires 2033-08-08

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on February 12, 2025.

F3 · derivative.exercise_date: 25% of the shares underlying this option vested on July 24, 2024, with the remainder vesting in twelve equal quarterly installments thereafter, subject to the Reporting Person's continued service on each such vesting date.