AXSM

SEC source: 0001193125-26-174417 · ownership.xml · derivative · entry 1

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 24,081

Underlying: Common Stock · 24,081 shares

Expires not disclosed

F1 · derivative.exercise_price: Each performance stock unit ("PSU") represents a contingent right to receive one share of the Issuer's common stock.

F2 · derivative.exercise_date: Each PSU will vest upon achievement of certain sales and commercial launch milestones, subject to the reporting person's continued service as of each vesting date.

F2 · derivative.expiration_date: Each PSU will vest upon achievement of certain sales and commercial launch milestones, subject to the reporting person's continued service as of each vesting date.

SEC source: 0001193125-26-174412 · ownership.xml · derivative · entry 1

Pizzie Nick · CIK 0001742143 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 8,188

Underlying: Common Stock · 8,188 shares

Expires not disclosed

F1 · derivative.exercise_price: Each performance stock unit ("PSU") represents a contingent right to receive one share of the Issuer's common stock.

F2 · derivative.exercise_date: Each PSU will vest upon achievement of certain sales and commercial launch milestones, subject to the reporting person's continued service as of each vesting date.

F2 · derivative.expiration_date: Each PSU will vest upon achievement of certain sales and commercial launch milestones, subject to the reporting person's continued service as of each vesting date.

SEC source: 0001193125-26-083606 · ownership.xml · derivative · entry 1

Maizel Ari · CIK 0002042289 · Chief Commercial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,385

Underlying: Common Stock · 16,385 shares

Expires 2036-02-26

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

F2 · derivative.exercise_date: 25% of the RSUs will vest on the one (1) year anniversary of the date of grant. The remaining RSUs will vest in three substantially equal annual installments, such that the RSUs will be fully vested on February 26, 2030. Vested shares will be delivered to the reporting person upon the earlier of (i) the closing of a Change in Control (as defined in the Issuer's 2025 Long-Term Incentive Plan ("2025 Plan")), (ii) the reporting person's separation of service from the Issuer (including termination with or without Cause (as defined in the 2025 Plan), or termination due to death or Total and Permanent Disability (as defined in the 2025 Plan)), or (iii) seven (7) years from the date of grant.

SEC source: 0001193125-26-083607 · ownership.xml · derivative · entry 1

Murdock Hunter R. · CIK 0001934008 · General Counsel

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 16,385

Underlying: Common Stock · 16,385 shares

Expires 2036-02-26

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

F2 · derivative.exercise_date: 25% of the RSUs will vest on the one (1) year anniversary of the date of grant. The remaining RSUs will vest in three substantially equal annual installments, such that the RSUs will be fully vested on February 26, 2030. Vested shares will be delivered to the reporting person upon the earlier of (i) the closing of a Change in Control (as defined in the Issuer's 2025 Long-Term Incentive Plan ("2025 Plan")), (ii) the reporting person's separation of service from the Issuer (including termination with or without Cause (as defined in the 2025 Plan), or termination due to death or Total and Permanent Disability (as defined in the 2025 Plan)), or (iii) seven (7) years from the date of grant.

SEC source: 0001193125-26-083605 · ownership.xml · derivative · entry 1

Jacobson Mark L. · CIK 0001805812 · Chief Operating Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 19,663

Underlying: Common Stock · 19,663 shares

Expires 2036-02-26

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

F2 · derivative.exercise_date: 25% of the RSUs will vest on the one (1) year anniversary of the date of grant. The remaining RSUs will vest in three substantially equal annual installments, such that the RSUs will be fully vested on February 26, 2030. Vested shares will be delivered to the reporting person upon the earlier of (i) the closing of a Change in Control (as defined in the Issuer's 2025 Long-Term Incentive Plan ("2025 Plan")), (ii) the reporting person's separation of service from the Issuer (including termination with or without Cause (as defined in the 2025 Plan), or termination due to death or Total and Permanent Disability (as defined in the 2025 Plan)), or (iii) seven (7) years from the date of grant.

SEC source: 0001193125-26-083586 · ownership.xml · derivative · entry 3

Jacobson Mark L. · CIK 0001805812 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 35,378 shares

Expires 2028-03-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-083586 · ownership.xml · nonDerivative · entry 2

Jacobson Mark L. · CIK 0001805812 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F4 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $160.10 and $163.42.

SEC source: 0001193125-26-083586 · ownership.xml · nonDerivative · entry 1

Jacobson Mark L. · CIK 0001805812 · Chief Operating Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 35,378

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-083587 · ownership.xml · nonDerivative · entry 1

Coleman Mark · CIK 0001658379 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 47,140

F1 · kind: Represents the sale of underlying shares of previously exercised stock options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan, which has now been completed.

F3 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $160.33 and $162.26.

SEC source: 0001193125-26-083609 · ownership.xml · derivative · entry 1

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 54,623

Underlying: Common Stock · 54,623 shares

Expires 2036-02-26

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

F2 · derivative.exercise_date: 25% of the RSUs will vest on the one (1) year anniversary of the date of grant. The remaining RSUs will vest in three substantially equal annual installments, such that the RSUs will be fully vested on February 26, 2030. Vested shares will be delivered to the reporting person upon the earlier of (i) the closing of a Change in Control (as defined in the Issuer's 2025 Long-Term Incentive Plan ("2025 Plan")), (ii) the reporting person's separation of service from the Issuer (including termination with or without Cause (as defined in the 2025 Plan), or termination due to death or Total and Permanent Disability (as defined in the 2025 Plan)), or (iii) seven (7) years from the date of grant.

SEC source: 0001193125-26-083608 · ownership.xml · derivative · entry 1

Pizzie Nick · CIK 0001742143 · Chief Financial Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 18,570

Underlying: Common Stock · 18,570 shares

Expires 2036-02-26

F1 · derivative.exercise_price: Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

F2 · derivative.exercise_date: 25% of the RSUs will vest on the one (1) year anniversary of the date of grant. The remaining RSUs will vest in three substantially equal annual installments, such that the RSUs will be fully vested on February 26, 2030. Vested shares will be delivered to the reporting person upon the earlier of (i) the closing of a Change in Control (as defined in the Issuer's 2025 Long-Term Incentive Plan ("2025 Plan")), (ii) the reporting person's separation of service from the Issuer (including termination with or without Cause (as defined in the 2025 Plan), or termination due to death or Total and Permanent Disability (as defined in the 2025 Plan)), or (iii) seven (7) years from the date of grant.

SEC source: 0001193125-26-072481 · ownership.xml · derivative · entry 3

Coleman Mark · CIK 0001658379 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 7,721

Underlying: Common Stock · 6,250 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents the exercise of stock options, prior to the 10-year expiration date, for cash and hold of underlying shares.

SEC source: 0001193125-26-072481 · ownership.xml · nonDerivative · entry 1

Coleman Mark · CIK 0001658379 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 72,140

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents the exercise of stock options, prior to the 10-year expiration date, for cash and hold of underlying shares.

SEC source: 0001193125-26-064681 · ownership.xml · derivative · entry 3

Coleman Mark · CIK 0001658379 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 13,971

Underlying: Common Stock · 12,485 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents the exercise of stock options, prior to the 10-year expiration date, for cash and hold of underlying shares.

SEC source: 0001193125-26-064681 · ownership.xml · nonDerivative · entry 1

Coleman Mark · CIK 0001658379 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 65,890

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents the exercise of stock options, prior to the 10-year expiration date, for cash and hold of underlying shares.

SEC source: 0001193125-26-045110 · ownership.xml · derivative · entry 3

Coleman Mark · CIK 0001658379 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 5,193 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents the exercise of stock options, prior to the 10-year expiration date, for cash and hold of underlying shares.

SEC source: 0001193125-26-045110 · ownership.xml · nonDerivative · entry 1

Coleman Mark · CIK 0001658379 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 53,405

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents the exercise of stock options, prior to the 10-year expiration date, for cash and hold of underlying shares.

SEC source: 0001193125-26-033973 · ownership.xml · derivative · entry 4

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 32,410 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan, which has now been completed.

SEC source: 0001193125-26-033973 · ownership.xml · nonDerivative · entry 2

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,229

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan, which has now been completed.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F4 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $183.85 and $186.89.

SEC source: 0001193125-26-033973 · ownership.xml · nonDerivative · entry 1

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 39,639

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan, which has now been completed.

SEC source: 0001193125-26-021378 · ownership.xml · derivative · entry 4

Pizzie Nick · CIK 0001742143 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 105,000

Underlying: Common Stock · 12,000 shares

Expires 2028-05-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-021378 · ownership.xml · nonDerivative · entry 2

Pizzie Nick · CIK 0001742143 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 42,588

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F4 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $185.09 and $191.12.

F5 · balance_after: Includes the prior purchase of shares of common stock pursuant to the Issuer's Employee Stock Purchase Plan.

SEC source: 0001193125-26-021378 · ownership.xml · nonDerivative · entry 1

Pizzie Nick · CIK 0001742143 · Chief Financial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 54,588

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents an exercise of stock options which was held for 8 years and exercised prior to the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F5 · balance_after: Includes the prior purchase of shares of common stock pursuant to the Issuer's Employee Stock Purchase Plan.

SEC source: 0001193125-26-021377 · ownership.xml · derivative · entry 3

Maizel Ari · CIK 0002042289 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 31,210

Underlying: Common Stock · 7,500 shares

Expires 2033-09-25

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-021377 · ownership.xml · nonDerivative · entry 2

Maizel Ari · CIK 0002042289 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

F1 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F2 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F3 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $183.70 and $184.81.

SEC source: 0001193125-26-021377 · ownership.xml · nonDerivative · entry 1

Maizel Ari · CIK 0002042289 · Chief Commercial Officer

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-006695 · ownership.xml · derivative · entry 10

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 32,410

Underlying: Common Stock · 31,261 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-006695 · ownership.xml · nonDerivative · entry 6

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,229

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F6 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $168.15 and $173.17.

SEC source: 0001193125-26-006695 · ownership.xml · nonDerivative · entry 5

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 38,490

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-006695 · ownership.xml · derivative · entry 9

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 63,671

Underlying: Common Stock · 29,450 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-006695 · ownership.xml · nonDerivative · entry 4

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,229

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F5 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $170.36 and $175.26.

SEC source: 0001193125-26-006695 · ownership.xml · nonDerivative · entry 3

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 36,679

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-006695 · ownership.xml · derivative · entry 8

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 93,121

Underlying: Common Stock · 78,703 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-006695 · ownership.xml · nonDerivative · entry 2

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,229

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F4 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $168.58 and $178.60.

SEC source: 0001193125-26-006695 · ownership.xml · nonDerivative · entry 1

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 85,932

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-001181 · ownership.xml · derivative · entry 7

Saad Mark E · CIK 0001295913 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 31,346 shares

Expires 2027-03-15

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents an exercise of stock options prior to the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-001181 · ownership.xml · derivative · entry 6

Saad Mark E · CIK 0001295913 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 6,231 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents an exercise of stock options prior to the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-001181 · ownership.xml · nonDerivative · entry 4

Saad Mark E · CIK 0001295913 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,002

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F4 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $165.00 and $166.09.

SEC source: 0001193125-26-001181 · ownership.xml · nonDerivative · entry 3

Saad Mark E · CIK 0001295913 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 41,348

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents an exercise of stock options prior to the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-26-001181 · ownership.xml · nonDerivative · entry 2

Saad Mark E · CIK 0001295913 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 10,002

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F4 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $165.00 and $166.09.

SEC source: 0001193125-26-001181 · ownership.xml · nonDerivative · entry 1

Saad Mark E · CIK 0001295913 · Director

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 16,233

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Represents an exercise of stock options prior to the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-25-308354 · ownership.xml · derivative · entry 10

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 171,824

Underlying: Common Stock · 10,558 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-25-308354 · ownership.xml · nonDerivative · entry 6

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,229

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F6 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $146.77 and $149.41.

SEC source: 0001193125-25-308354 · ownership.xml · nonDerivative · entry 5

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 17,787

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-25-308354 · ownership.xml · derivative · entry 9

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 182,382

Underlying: Common Stock · 20,163 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-25-308354 · ownership.xml · nonDerivative · entry 4

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,229

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F5 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $142.66 and $148.39.

SEC source: 0001193125-25-308354 · ownership.xml · nonDerivative · entry 3

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 27,392

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-25-308354 · ownership.xml · derivative · entry 8

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 202,545

Underlying: Common Stock · 49,252 shares

Expires 2026-05-27

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

SEC source: 0001193125-25-308354 · ownership.xml · nonDerivative · entry 2

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 7,229

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.

F3 · kind: Represents the subsequent sale of the underlying shares of the aforementioned exercise of stock options.

F4 · price: Represents the weighted average sale price of a series of open market transactions with sale prices ranging between $141.79 and $149.23.

SEC source: 0001193125-25-308354 · ownership.xml · nonDerivative · entry 1

TABUTEAU HERRIOT · CIK 0001219927 · Director · Chief Executive Officer · 10% owner

10b5-1 filing: Plan reported

Ownership: Direct

Disclosed balance after: 56,481

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Necessary exercise of stock options set to expire due to attainment of the 10-year expiration date of such options.

F2 · kind: Such transaction was pursuant to a pre-approved 10b5-1 plan.