AWHL

SEC source: 0001623017-18-000003 · primary_doc.xml · nonDerivative · entry 1

Palmieri Valerie Barber · CIK 0001623017 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,063

SEC source: 0001162956-18-000002 · primary_doc.xml · nonDerivative · entry 2

LAFRANCE JAMES T · CIK 0001162956 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 301,418

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F3 · price: The sale reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $0.4710 to $0.5150 per share. The reporting person undertakes to provide to Vermillion, any security holder of Vermillion or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001725914-18-000002 · primary_doc.xml · nonDerivative · entry 1

Beechey Robert Harry · CIK 0001725914 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

F1 · price: The purchase reported in column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $0.515713 to $0.519931 per share. The reporting person undertakes to provide to Vermillion, any security holder of Vermillion or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0001162956-18-000002 · primary_doc.xml · nonDerivative · entry 1

LAFRANCE JAMES T · CIK 0001162956 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 318,845

F1 · shares: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.

F2 · price: The sale reported in column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $0.5150 to $0.5156 per share. The reporting person undertakes to provide to Vermillion, any security holder of Vermillion or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each price within the range set forth in this footnote.

SEC source: 0000905148-18-000588 · form4.xml · derivative · entry 10

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler Grandchildren LLC

Disclosed balance after: 0

Underlying: Common Stock · 245,800 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share..

F8 · derivative.expiration_date: The Preferred Stock has no expiration date.

F4 · ownership.nature: These Shares and Preferred Stock are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000588 · form4.xml · derivative · entry 9

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler GC 2010 Continuation Trust

Disclosed balance after: 0

Underlying: Common Stock · 54,700 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share..

F8 · derivative.expiration_date: The Preferred Stock has no expiration date.

F3 · ownership.nature: These Shares and Preferred Stock are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000588 · form4.xml · derivative · entry 8

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Therese Heidi Schuler Trust

Disclosed balance after: 2,458

Underlying: Common Stock · 245,800 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share..

F8 · derivative.expiration_date: The Preferred Stock has no expiration date.

F2 · ownership.nature: These Shares and Preferred Stock are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000588 · form4.xml · derivative · entry 7

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Tanya Eva Schuler Trust

Disclosed balance after: 0

Underlying: Common Stock · 245,900 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share..

F8 · derivative.expiration_date: The Preferred Stock has no expiration date.

F1 · ownership.nature: These shares of Common Stock ("Shares") and Series B Convertible Preferred Stock ("Preferred Stock") are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000588 · form4.xml · nonDerivative · entry 4

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler Grandchildren LLC

Disclosed balance after: 1,253,177

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share..

F4 · ownership.nature: These Shares and Preferred Stock are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000588 · form4.xml · nonDerivative · entry 3

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler GC 2010 Continuation Trust

Disclosed balance after: 1,040,068

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share..

F3 · ownership.nature: These Shares and Preferred Stock are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000588 · form4.xml · nonDerivative · entry 2

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Therese Heidi Schuler Trust

Disclosed balance after: 3,796,957

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share..

F2 · ownership.nature: These Shares and Preferred Stock are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000588 · form4.xml · nonDerivative · entry 1

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Tanya Eva Schuler Trust

Disclosed balance after: 3,797,057

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share..

F1 · ownership.nature: These shares of Common Stock ("Shares") and Series B Convertible Preferred Stock ("Preferred Stock") are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000587 · form4.xml · derivative · entry 2

SCHULER JACK W · CIK 0001021412 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 3,961,900 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share.

F2 · derivative.expiration_date: The Preferred Stock had no expiration date.

F3 · ownership.nature: These shares of Common Stock ("Shares") and Preferred Stock are directly held by the Jack W. Schuler Living Trust. Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0000905148-18-000587 · form4.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 17,378,242

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: On June 21, 2018, as a result of receipt of the Requisite Stockholder Approval (defined and described further in the reporting person's amendment to Schedule 13D filed on April 19, 2018), each share of Series B Convertible Preferred Stock ("Preferred Stock") automatically converted into 100 shares of Common Stock, reflecting a conversion price equal to $1.00 per share.

F3 · ownership.nature: These shares of Common Stock ("Shares") and Preferred Stock are directly held by the Jack W. Schuler Living Trust. Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0000905148-18-000456 · form4.xml · derivative · entry 10

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler Grandchildren LLC

Disclosed balance after: 2,458

Underlying: Common Stock · 245,800 shares

Expires not disclosed

F7 · derivative.exercise_price: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F7 · derivative.exercise_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F7 · derivative.expiration_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F4 · ownership.nature: These Shares and Preferred Stock are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000456 · form4.xml · derivative · entry 9

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler GC 2010 Continuation Trust

Disclosed balance after: 547

Underlying: Common Stock · 54,700 shares

Expires not disclosed

F7 · derivative.exercise_price: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F7 · derivative.exercise_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F7 · derivative.expiration_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F3 · ownership.nature: These Shares and Preferred Stock are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000456 · form4.xml · derivative · entry 8

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Therese Heidi Schuler Trust

Disclosed balance after: 2,458

Underlying: Common Stock · 245,800 shares

Expires not disclosed

F7 · derivative.exercise_price: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F7 · derivative.exercise_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F7 · derivative.expiration_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F2 · ownership.nature: These Shares and Preferred Stock are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000456 · form4.xml · derivative · entry 7

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Tanya Eva Schuler Trust

Disclosed balance after: 2,459

Underlying: Common Stock · 245,900 shares

Expires not disclosed

F7 · derivative.exercise_price: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F7 · derivative.exercise_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F7 · derivative.expiration_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F1 · ownership.nature: These shares of Common Stock ("Shares") and Series B Convertible Preferred Stock ("Preferred Stock") are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000456 · form4.xml · nonDerivative · entry 4

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler Grandchildren LLC

Disclosed balance after: 1,007,377

F4 · ownership.nature: These Shares and Preferred Stock are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000456 · form4.xml · nonDerivative · entry 3

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler GC 2010 Continuation Trust

Disclosed balance after: 985,368

F3 · ownership.nature: These Shares and Preferred Stock are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000456 · form4.xml · nonDerivative · entry 2

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Therese Heidi Schuler Trust

Disclosed balance after: 3,551,157

F2 · ownership.nature: These Shares and Preferred Stock are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000456 · form4.xml · nonDerivative · entry 1

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Tanya Eva Schuler Trust

Disclosed balance after: 3,551,157

F1 · ownership.nature: These shares of Common Stock ("Shares") and Series B Convertible Preferred Stock ("Preferred Stock") are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust.

F6 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares and Preferred Stock except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-18-000454 · form4.xml · derivative · entry 2

SCHULER JACK W · CIK 0001021412 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 39,619

Underlying: Common Stock · 3,961,900 shares

Expires not disclosed

F2 · derivative.exercise_price: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F2 · derivative.exercise_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F2 · derivative.expiration_date: Each share of Preferred Stock is initially convertible into 100 Shares automatically upon the Requisite Stockholder Approval (defined and described further in the Schedule 13D/A filed by the Reporting Person on April 19, 2018), subject to customary anti-dilution adjustments, reflecting an initial conversion price equal to $1.00 per share. The Preferred Stock has no expiration date.

F1 · ownership.nature: These shares of Common Stock ("Shares") and Series B Convertible Preferred Stock ("Preferred Stock") are directly held by the Jack W. Schuler Living Trust. Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0000905148-18-000454 · form4.xml · nonDerivative · entry 1

SCHULER JACK W · CIK 0001021412 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 13,416,342

F1 · ownership.nature: These shares of Common Stock ("Shares") and Series B Convertible Preferred Stock ("Preferred Stock") are directly held by the Jack W. Schuler Living Trust. Jack W. Schuler is the sole trustee of the Jack W. Schuler Living Trust.

SEC source: 0001725914-18-000001 · primary_doc.xml · derivative · entry 1

Beechey Robert Harry · CIK 0001725914 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Common Stock · 150,000 shares

Expires 2028-04-13

F1 · derivative.exercise_date: The option vests in four equal annual installments beginning on April 13, 2019.

SEC source: 0001637904-18-000002 · primary_doc.xml · derivative · entry 1

FERRARA FRED · CIK 0001637904 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 15,000

Underlying: Common Stock · 15,000 shares

Expires 2026-11-08

F1 · derivative.exercise_date: An option to purchase 60,000 shares of common stock was granted to the reporting person on 11/8/16, subject to the satisfaction of certain performance conditions. On 4/13/18, a portion of the performance conditions were deemed to have been met, resulting in 15,000 shares earned. The remaining option to purchase 45,000 shares was canceled. Half of the achieved portion of the option grant is immediately exercisable and the remaining 50% will vest on 12/31/18.

SEC source: 0001637904-18-000001 · primary_doc.xml · derivative · entry 1

FERRARA FRED · CIK 0001637904 · Chief Operating Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2028-04-13

F1 · derivative.exercise_date: The option vests in four equal annual installments beginning on April 13, 2019.

SEC source: 0001623017-18-000002 · primary_doc.xml · derivative · entry 1

Palmieri Valerie Barber · CIK 0001623017 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 100,000

Underlying: Common Stock · 100,000 shares

Expires 2026-11-08

F1 · derivative.exercise_date: An option to purchase 350,000 shares of common stock was granted to the reporting person on 11/8/16, subject to the satisfaction of certain performance conditions. On 4/13/18, a portion of the performance conditions were deemed to have been met, resulting in 100,000 shares earned. The remaining option to purchase 250,000 shares was canceled. Half of the achieved portion of the option grant is immediately exercisable and the remaining 50% will vest on 12/31/18.

SEC source: 0001623017-18-000001 · primary_doc.xml · derivative · entry 1

Palmieri Valerie Barber · CIK 0001623017 · Director · President & CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 450,000

Underlying: Common Stock · 450,000 shares

Expires 2028-04-13

F1 · derivative.exercise_date: The option vests in four equal annual installments beginning on April 13, 2019.

SEC source: 0001562762-18-000133 · certent-form4.xml · nonDerivative · entry 1

Jordan Veronica GH · CIK 0001381123 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 175,517

F1 · shares: The shares of common stock represent restricted stock units with contingent right to receive one share of common stock of Vermillion, Inc. for each restricted stock unit. 50% of the restricted stock units will vest on June 1, 2018, 25% of the restricted stock units will vest on September 1, 2018 and 25% of the restricted stock units will vest on December 1, 2018.

SEC source: 0001294046-18-000001 · primary_doc.xml · nonDerivative · entry 1

Burns James S · CIK 0001294046 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 362,207

F1 · shares: The shares of common stock represent restricted stock units with contingent right to receive one share of common stock of Vermillion, Inc. for each restricted stock unit. 50% of the restricted stock units will vest on June 1, 2018, 25% of the restricted stock units will vest on September 1, 2018 and 25% of the restricted stock units will vest on December 1, 2018.

SEC source: 0001488364-18-000001 · primary_doc.xml · nonDerivative · entry 1

Severinghaus Carl · CIK 0001488364 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 282,296

F1 · shares: The shares of common stock represent restricted stock units with contingent right to receive one share of common stock of Vermillion, Inc. for each restricted stock unit. 50% of the restricted stock units will vest on June 1, 2018, 25% of the restricted stock units will vest on September 1, 2018 and 25% of the restricted stock units will vest on December 1, 2018.

SEC source: 0001162956-18-000001 · primary_doc.xml · nonDerivative · entry 1

LAFRANCE JAMES T · CIK 0001162956 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 321,418

F1 · shares: The shares of common stock represent restricted stock units with contingent right to receive one share of common stock of Vermillion, Inc. for each restricted stock unit. 50% of the restricted stock units will vest on June 1, 2018, 25% of the restricted stock units will vest on September 1, 2018 and 25% of the restricted stock units will vest on December 1, 2018.

SEC source: 0001255627-18-000001 · primary_doc.xml · nonDerivative · entry 1

SCHREIBER DAVID · CIK 0001255627 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 167,405

F1 · shares: The shares of common stock represent restricted stock units with contingent right to receive one share of common stock of Vermillion, Inc. for each restricted stock unit. 50% of the restricted stock units will vest on June 1, 2018, 25% of the restricted stock units will vest on September 1, 2018 and 25% of the restricted stock units will vest on December 1, 2018.

SEC source: 0001725914-17-000002 · primary_doc.xml · derivative · entry 1

Beechey Robert Harry · CIK 0001725914 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 150,000

Underlying: Common Stock · 150,000 shares

Expires 2027-12-18

F1 · derivative.exercise_date: The option vests in four equal annual installments beginning on December 18, 2018.

SEC source: 0001623017-17-000009 · primary_doc.xml · nonDerivative · entry 1

Palmieri Valerie Barber · CIK 0001623017 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,963

F1 · shares: The purchase reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 25, 2017.

SEC source: 0001623017-17-000008 · primary_doc.xml · nonDerivative · entry 1

Palmieri Valerie Barber · CIK 0001623017 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 61,278

F1 · shares: The purchase reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 25, 2017.

SEC source: 0001623017-17-000007 · primary_doc.xml · nonDerivative · entry 1

Palmieri Valerie Barber · CIK 0001623017 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 60,584

F1 · shares: The purchase reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 25, 2017.

SEC source: 0001140361-17-034022 · doc1.xml · derivative · entry 2

FEINBERG LARRY N · CIK 0000926475 · 10% owner · * See Remarks

ORACLE PARTNERS LP · CIK 0000941901 · 10% owner · * See Remarks

Oracle Ten Fund Master, LP · CIK 0001577258 · 10% owner · * See Remarks

ORACLE INSTITUTIONAL PARTNERS L P · CIK 0000924141 · 10% owner · * See Remarks

Oracle Associates LLC · CIK 0001317217 · 10% owner · * See Remarks

ORACLE INVESTMENT MANAGEMENT INC · CIK 0001012622 · 10% owner · * See Remarks

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 0

Underlying: Common Stock · 583,333 shares

Expires 2017-08-31

F2 · price: See Exhibit 99.1, Note 2.

F1 · ownership.nature: See Exhibit 99.1, Note1.

SEC source: 0001140361-17-034022 · doc1.xml · nonDerivative · entry 1

FEINBERG LARRY N · CIK 0000926475 · 10% owner · * See Remarks

ORACLE PARTNERS LP · CIK 0000941901 · 10% owner · * See Remarks

Oracle Ten Fund Master, LP · CIK 0001577258 · 10% owner · * See Remarks

ORACLE INSTITUTIONAL PARTNERS L P · CIK 0000924141 · 10% owner · * See Remarks

Oracle Associates LLC · CIK 0001317217 · 10% owner · * See Remarks

ORACLE INVESTMENT MANAGEMENT INC · CIK 0001012622 · 10% owner · * See Remarks

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See footnote

Disclosed balance after: 9,825,289

F1 · ownership.nature: See Exhibit 99.1, Note1.

SEC source: 0000905148-17-000784 · form4.xml · derivative · entry 12

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler Grandchildren LLC

Disclosed balance after: 0

Underlying: Common Stock · 113,332 shares

Expires 2017-08-31

F5 · ownership.nature: These Shares are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · derivative · entry 11

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler GC 2010 Continuation Trust

Disclosed balance after: 0

Underlying: Common Stock · 113,332 shares

Expires 2017-08-31

F4 · ownership.nature: These Shares and Warrants are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · derivative · entry 10

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Therese Heidi Schuler Trust

Disclosed balance after: 0

Underlying: Common Stock · 571,702 shares

Expires 2017-08-31

F3 · ownership.nature: These Shares and Warrants are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · derivative · entry 9

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Tanya Eva Schuler Trust

Disclosed balance after: 0

Underlying: Common Stock · 571,702 shares

Expires 2017-08-31

F2 · ownership.nature: These Shares and Warrants are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · derivative · entry 8

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Tino Hans Schuler Trust

Disclosed balance after: 0

Underlying: Common Stock · 571,702 shares

Expires 2017-08-31

F1 · ownership.nature: These Shares of Common Stock ("Shares") and Warrants to acquire Common Stock ("Warrants") are directly owned by the Tino Hans Schuler Trust. H. George Schuler is the sole trustee of the Tino Hans Schuler Trust.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · nonDerivative · entry 5

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler Grandchildren LLC

Disclosed balance after: 353,240

F5 · ownership.nature: These Shares are directly owned by the Schuler Grandchildren LLC. H. George Schuler is the manager of the Schuler Grandchildren LLC.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · nonDerivative · entry 4

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Schuler GC 2010 Continuation Trust

Disclosed balance after: 840,003

F4 · ownership.nature: These Shares and Warrants are directly owned by the Schuler GC 2010 Continuation Trust. H. George Schuler is the sole trustee of the Schuler GC 2010 Continuation Trust.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · nonDerivative · entry 3

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Therese Heidi Schuler Trust

Disclosed balance after: 2,897,021

F3 · ownership.nature: These Shares and Warrants are directly owned by the Therese Heidi Schuler Trust. H. George Schuler is the sole trustee of the Therese Heidi Schuler Trust.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · nonDerivative · entry 2

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Tanya Eva Schuler Trust

Disclosed balance after: 2,897,021

F2 · ownership.nature: These Shares and Warrants are directly owned by the Tanya Eva Schuler Trust. H. George Schuler is the sole trustee of the Tanya Eva Schuler Trust.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

SEC source: 0000905148-17-000784 · form4.xml · nonDerivative · entry 1

Schuler Henri George · CIK 0001629151 · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · By Tino Hans Schuler Trust

Disclosed balance after: 2,897,021

F1 · ownership.nature: These Shares of Common Stock ("Shares") and Warrants to acquire Common Stock ("Warrants") are directly owned by the Tino Hans Schuler Trust. H. George Schuler is the sole trustee of the Tino Hans Schuler Trust.

F7 · ownership.nature: The reporting person disclaims beneficial ownership of these Shares except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that he is the beneficial owner of the Shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.