AURA

SEC source: 0000950170-25-109767 · ownership.xml · derivative · entry 15

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,319 shares

Expires 2030-03-16

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-109767 · ownership.xml · derivative · entry 14

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,094 shares

Expires 2029-02-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-109767 · ownership.xml · derivative · entry 13

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 4,744 shares

Expires 2028-02-21

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-109767 · ownership.xml · derivative · entry 12

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 547 shares

Expires 2027-04-12

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-109767 · ownership.xml · derivative · entry 11

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 547 shares

Expires 2026-10-26

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-109767 · ownership.xml · derivative · entry 10

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 1,094 shares

Expires 2026-04-11

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-109767 · ownership.xml · derivative · entry 9

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 2,554 shares

Expires 2025-09-03

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-109767 · ownership.xml · nonDerivative · entry 8

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 86,558

F1 · kind: On August 18, 2025, the Reporting Person exercised long held stock options to purchase 12,899 shares of the Issuer's common stock, 7,722 of which were sold to cover the exercise price of such options.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.57 to $6.80, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000950170-25-109767 · ownership.xml · nonDerivative · entry 7

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 94,280

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On August 18, 2025, the Reporting Person exercised long held stock options to purchase 12,899 shares of the Issuer's common stock, 7,722 of which were sold to cover the exercise price of such options.

SEC source: 0000950170-25-109767 · ownership.xml · nonDerivative · entry 6

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 91,961

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On August 18, 2025, the Reporting Person exercised long held stock options to purchase 12,899 shares of the Issuer's common stock, 7,722 of which were sold to cover the exercise price of such options.

SEC source: 0000950170-25-109767 · ownership.xml · nonDerivative · entry 5

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 90,867

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On August 18, 2025, the Reporting Person exercised long held stock options to purchase 12,899 shares of the Issuer's common stock, 7,722 of which were sold to cover the exercise price of such options.

SEC source: 0000950170-25-109767 · ownership.xml · nonDerivative · entry 4

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 86,123

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On August 18, 2025, the Reporting Person exercised long held stock options to purchase 12,899 shares of the Issuer's common stock, 7,722 of which were sold to cover the exercise price of such options.

SEC source: 0000950170-25-109767 · ownership.xml · nonDerivative · entry 3

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,576

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On August 18, 2025, the Reporting Person exercised long held stock options to purchase 12,899 shares of the Issuer's common stock, 7,722 of which were sold to cover the exercise price of such options.

SEC source: 0000950170-25-109767 · ownership.xml · nonDerivative · entry 2

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 85,029

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On August 18, 2025, the Reporting Person exercised long held stock options to purchase 12,899 shares of the Issuer's common stock, 7,722 of which were sold to cover the exercise price of such options.

SEC source: 0000950170-25-109767 · ownership.xml · nonDerivative · entry 1

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,935

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: On August 18, 2025, the Reporting Person exercised long held stock options to purchase 12,899 shares of the Issuer's common stock, 7,722 of which were sold to cover the exercise price of such options.

SEC source: 0000950170-25-087890 · ownership.xml · derivative · entry 5

Johnson David Michael · CIK 0001808098 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,000

Underlying: Common Stock · 17,000 shares

Expires 2035-06-17

F5 · derivative.exercise_date: This stock option will vest and become exercisable in full upon the earlier to occur of (a) June 17, 2026 or (b) the next annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service as of such vesting date.

SEC source: 0000950170-25-087890 · ownership.xml · nonDerivative · entry 1

Johnson David Michael · CIK 0001808098 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 179,167

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in full upon the earlier to occur of (a) June 17, 2026 or (b) the next annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service as of such vesting date.

SEC source: 0000950170-25-087889 · ownership.xml · derivative · entry 2

Mattessich Antony C. · CIK 0001709900 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,000

Underlying: Common Stock · 17,000 shares

Expires 2035-06-17

F2 · derivative.exercise_date: This stock option will vest and become exercisable in full upon the earlier to occur of (a) June 17, 2026 or (b) the next annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service as of such vesting date.

SEC source: 0000950170-25-087889 · ownership.xml · nonDerivative · entry 1

Mattessich Antony C. · CIK 0001709900 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,500

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in full upon the earlier to occur of (a) June 17, 2026 or (b) the next annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service as of such vesting date.

SEC source: 0000950170-25-087891 · ownership.xml · derivative · entry 2

Srivastava Sapna · CIK 0001569226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 17,000

Underlying: Common Stock · 17,000 shares

Expires 2035-06-17

F2 · derivative.exercise_date: This stock option will vest and become exercisable in full upon the earlier to occur of (a) June 17, 2026 or (b) the next annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service as of such vesting date.

SEC source: 0000950170-25-087891 · ownership.xml · nonDerivative · entry 1

Srivastava Sapna · CIK 0001569226 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 23,500

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in full upon the earlier to occur of (a) June 17, 2026 or (b) the next annual meeting of the Issuer's stockholders, subject to the Reporting Person's continued service as of such vesting date.

SEC source: 0000950170-25-081615 · ownership.xml · derivative · entry 4

de los Pinos Elisabet · CIK 0001889633 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 0

Underlying: Common Stock · 10,948 shares

Expires 2025-06-02

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These shares were acquired and/or withheld to cover the exercise price and resulting tax obligations, as applicable, in connection with a net (cashless) exercise of stock options. The stock options subject to the net exercise were to expire June 2, 2025. These transactions were completed subsequent to the execution of a Lock-Up Agreement and the shares received are subject to the provisions of that agreement.

F3 · derivative.exercise_date: This option is fully vested.

SEC source: 0000950170-25-081615 · ownership.xml · nonDerivative · entry 2

de los Pinos Elisabet · CIK 0001889633 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 483,440

F1 · kind: These shares were acquired and/or withheld to cover the exercise price and resulting tax obligations, as applicable, in connection with a net (cashless) exercise of stock options. The stock options subject to the net exercise were to expire June 2, 2025. These transactions were completed subsequent to the execution of a Lock-Up Agreement and the shares received are subject to the provisions of that agreement.

SEC source: 0000950170-25-081615 · ownership.xml · nonDerivative · entry 1

de los Pinos Elisabet · CIK 0001889633 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 493,388

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: These shares were acquired and/or withheld to cover the exercise price and resulting tax obligations, as applicable, in connection with a net (cashless) exercise of stock options. The stock options subject to the net exercise were to expire June 2, 2025. These transactions were completed subsequent to the execution of a Lock-Up Agreement and the shares received are subject to the provisions of that agreement.

SEC source: 0000950170-25-081616 · ownership.xml · derivative · entry 2

Gibney Anthony S · CIK 0001750132 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 250,000

Underlying: Common Stock · 250,000 shares

Expires 2035-06-02

F2 · derivative.exercise_date: The shares underlying this option vest as follows: 25% of the shares vest on May 13, 2026 with the remainder vesting thereafter pro-rata in 36 monthly installments, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-081616 · ownership.xml · nonDerivative · entry 1

Gibney Anthony S · CIK 0001750132 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 206,933

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in four substantially equal annual installments beginning on June 15, 2026, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-075412 · ownership.xml · derivative · entry 5

Johnson David Michael · CIK 0001808098 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 5,000 shares

Expires 2030-05-16

F1 · kind: On May 16, 2025, the Reporting Person purchased 20,000 shares of the Issuer's common stock and a warrant to purchase 5,000 shares of the Issuer's common stock at a purchase price of $4.90 in an underwritten public offering.

F1 · price: On May 16, 2025, the Reporting Person purchased 20,000 shares of the Issuer's common stock and a warrant to purchase 5,000 shares of the Issuer's common stock at a purchase price of $4.90 in an underwritten public offering.

SEC source: 0000950170-25-075412 · ownership.xml · nonDerivative · entry 1

Johnson David Michael · CIK 0001808098 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 166,167

F1 · kind: On May 16, 2025, the Reporting Person purchased 20,000 shares of the Issuer's common stock and a warrant to purchase 5,000 shares of the Issuer's common stock at a purchase price of $4.90 in an underwritten public offering.

SEC source: 0000950170-25-075403 · ownership.xml · derivative · entry 3

Gibney Anthony S · CIK 0001750132 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 12,500 shares

Expires 2030-05-16

F1 · kind: On May 16, 2025, the Reporting Person purchased 50,000 shares of the Issuer's common stock and a warrant to purchase 12,500 shares of the Issuer's common stock at a purchase price of $4.90 in an underwritten public offering.

F1 · price: On May 16, 2025, the Reporting Person purchased 50,000 shares of the Issuer's common stock and a warrant to purchase 12,500 shares of the Issuer's common stock at a purchase price of $4.90 in an underwritten public offering.

SEC source: 0000950170-25-075403 · ownership.xml · nonDerivative · entry 2

Gibney Anthony S · CIK 0001750132 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 56,933

F2 · kind: The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.

SEC source: 0000950170-25-075403 · ownership.xml · nonDerivative · entry 1

Gibney Anthony S · CIK 0001750132 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 58,452

F1 · kind: On May 16, 2025, the Reporting Person purchased 50,000 shares of the Issuer's common stock and a warrant to purchase 12,500 shares of the Issuer's common stock at a purchase price of $4.90 in an underwritten public offering.

SEC source: 0000950170-25-054953 · ownership.xml · nonDerivative · entry 1

Kilroy Conor · CIK 0001808510 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 179,313

F1 · kind: The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.48 to $5.49, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000950170-25-054954 · ownership.xml · nonDerivative · entry 1

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 81,381

F1 · kind: The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.49 to $5.57, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000950170-25-049279 · ownership.xml · derivative · entry 2

Bitetti Teresa Marie · CIK 0001977608 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,000

Underlying: Common Stock · 29,000 shares

Expires 2035-03-31

F2 · derivative.exercise_date: The shares underlying this option vest in three substantially equal annual installments beginning on March 31, 2026, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-049279 · ownership.xml · nonDerivative · entry 1

Bitetti Teresa Marie · CIK 0001977608 · Director

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 21,000

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in three substantially equal annual installments beginning on April 15, 2026, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-022654 · ownership.xml · nonDerivative · entry 1

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 82,278

F1 · kind: The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.

SEC source: 0000950170-25-022651 · ownership.xml · nonDerivative · entry 1

de los Pinos Elisabet · CIK 0001889633 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 482,440

F1 · kind: The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $7.75 to $8.00, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

SEC source: 0000950170-25-022653 · ownership.xml · nonDerivative · entry 1

Hopkins Janet Jill · CIK 0001997710 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 269,794

F1 · kind: The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.

SEC source: 0000950170-25-022655 · ownership.xml · nonDerivative · entry 1

Plavsic Mark · CIK 0001868719 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 209,456

F1 · kind: The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.

SEC source: 0000950170-25-013827 · ownership.xml · derivative · entry 2

Kilroy Conor · CIK 0001808510 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,525

Underlying: Common Stock · 59,525 shares

Expires 2035-02-02

F2 · derivative.exercise_date: The shares underlying this option vest as follows: 25% of the shares vest on February 3, 2026 with the remainder vesting thereafter pro-rata in 36 monthly installments, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-013827 · ownership.xml · nonDerivative · entry 1

Kilroy Conor · CIK 0001808510 · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 186,475

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in four substantially equal annual installments beginning on February 15, 2026, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-013825 · ownership.xml · derivative · entry 2

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 29,760

Underlying: Common Stock · 29,760 shares

Expires 2035-02-02

F2 · derivative.exercise_date: The shares underlying this option vest as follows: 25% of the shares vest on February 3, 2026 with the remainder vesting thereafter pro-rata in 36 monthly installments, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-013825 · ownership.xml · nonDerivative · entry 1

Elazzouzi Amy · CIK 0002042910 · Senior Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 83,682

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in four substantially equal annual installments beginning on February 15, 2026, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-013830 · ownership.xml · derivative · entry 3

de los Pinos Elisabet · CIK 0001889633 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 255,680

Underlying: Common Stock · 255,680 shares

Expires 2035-02-02

F4 · derivative.exercise_date: The shares underlying this option vest as follows: 25% of the shares vest on February 3, 2026 with the remainder vesting thereafter pro-rata in 36 monthly installments, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-013830 · ownership.xml · nonDerivative · entry 1

de los Pinos Elisabet · CIK 0001889633 · Director · See Remarks

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 502,661

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in four substantially equal annual installments beginning on February 15, 2026, subject to the Reporting Person's continued service as of each such vesting date.

F2 · balance_after: On November 7, 2023, the Reporting Person filed a Form 4 which incorrectly included an additional 3,649 shares in the amount of securities beneficially owned directly after the reported transaction and excluded 3,649 shares from the amount of securities beneficially owned indirectly after the reported transaction. The Reporting Person's holdings after the transactions reported on this Form 4 reflect this correction.

SEC source: 0000950170-25-013829 · ownership.xml · derivative · entry 2

Plavsic Mark · CIK 0001868719 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 59,525

Underlying: Common Stock · 59,525 shares

Expires 2035-02-02

F2 · derivative.exercise_date: The shares underlying this option vest as follows: 25% of the shares vest on February 3, 2026 with the remainder vesting thereafter pro-rata in 36 monthly installments, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-013829 · ownership.xml · nonDerivative · entry 1

Plavsic Mark · CIK 0001868719 · Chief Technology Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 211,607

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in four substantially equal annual installments beginning on February 15, 2026, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-013828 · ownership.xml · derivative · entry 2

Hopkins Janet Jill · CIK 0001997710 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 79,365

Underlying: Common Stock · 79,365 shares

Expires 2035-02-02

F2 · derivative.exercise_date: The shares underlying this option vest as follows: 25% of the shares vest on February 3, 2026 with the remainder vesting thereafter pro-rata in 36 monthly installments, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-013828 · ownership.xml · nonDerivative · entry 1

Hopkins Janet Jill · CIK 0001997710 · Chief Medical Officer

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 272,328

F1 · shares: These shares were acquired pursuant to a restricted stock unit ("RSU") award under the Issuer's 2021 Stock Option and Incentive Plan. Each RSU represents the right to receive one share of the Issuer's Common Stock. These RSUs vest in four substantially equal annual installments beginning on February 15, 2026, subject to the Reporting Person's continued service as of each such vesting date.

SEC source: 0000950170-25-007494 · ownership.xml · nonDerivative · entry 1

Elazzouzi Amy · CIK 0002042910 · Vice President, Finance

10b5-1 filing: No plan indicated

Ownership: Direct

Disclosed balance after: 38,442

F1 · kind: The sales reported on this Form 4 represent the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. Such sales were automatic and not at the discretion of the Reporting Person.

F2 · price: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $7.67 to $7.86, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.