ARQT

SEC source: 0001567619-20-019438 · doc1.xml · nonDerivative · entry 1

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 179,844

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

SEC source: 0001567619-20-018694 · doc1.xml · derivative · entry 1

Curran Terrie · CIK 0001690298 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 37,500

Underlying: Common Stock · 37,500 shares

Expires 2030-11-02

F1 · derivative.exercise_date: The option vests as to 1/3 of the total shares on each of November 2, 2021, November 2, 2022 and November 2, 2023, subject to the Reporting Person's provision of service to the Issuer on each vesting date.

SEC source: 0001567619-20-018692 · doc1.xml · derivative · entry 6

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,772

Underlying: Common Stock · 1,809 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F4 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-018692 · doc1.xml · derivative · entry 5

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,057

Underlying: Common Stock · 391 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F4 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-018692 · doc1.xml · nonDerivative · entry 3

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 178,622

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · price: The transaction was executed in multiple trades in prices ranging from $18.02 to $18.63, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-018692 · doc1.xml · nonDerivative · entry 2

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 180,822

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-018692 · doc1.xml · nonDerivative · entry 1

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 179,013

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-018207 · doc1.xml · derivative · entry 2

Lock Kenneth A. · CIK 0001801047 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 147,080

Underlying: Common Stock · 2,668 shares

Expires 2029-10-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F3 · derivative.exercise_date: The option began vesting as to 1/4 of the total shares on October 14, 2020, and then 1/48 of the total shares vest monthly thereafter, with 100% of the total shares vested and exercisable on October 14, 2023, subject to the Reporting Person's provision of service to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-018207 · doc1.xml · nonDerivative · entry 1

Lock Kenneth A. · CIK 0001801047 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,863

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F2 · balance_after: Includes 9,000 Restricted Stock Units ("RSUs"). The Reporting Person is entitled to receive one (1) share of common stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-20-018132 · doc1.xml · derivative · entry 2

Lock Kenneth A. · CIK 0001801047 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 149,748

Underlying: Common Stock · 2,695 shares

Expires 2029-10-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F3 · derivative.exercise_date: The option began vesting as to 1/4 of the total shares on October 14, 2020, and then 1/48 of the total shares vest monthly thereafter, with 100% of the total shares vested and exercisable on October 14, 2023, subject to the Reporting Person's provision of service to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-018132 · doc1.xml · nonDerivative · entry 1

Lock Kenneth A. · CIK 0001801047 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,195

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F2 · balance_after: Includes 9,000 Restricted Stock Units ("RSUs"). The Reporting Person is entitled to receive one (1) share of common stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-20-017916 · doc1.xml · derivative · entry 2

Lock Kenneth A. · CIK 0001801047 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 152,443

Underlying: Common Stock · 7,500 shares

Expires 2029-10-28

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F3 · derivative.exercise_date: The option began vesting as to 1/4 of the total shares on October 14, 2020, and then 1/48 of the total shares vest monthly thereafter, with 100% of the total shares vested and exercisable on October 14, 2023, subject to the Reporting Person's provision of service to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-017916 · doc1.xml · nonDerivative · entry 1

Lock Kenneth A. · CIK 0001801047 · Chief Commercial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,500

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F2 · balance_after: Includes 9,000 Restricted Stock Units ("RSUs"). The Reporting Person is entitled to receive one (1) share of common stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-20-017915 · doc1.xml · derivative · entry 3

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,106

Underlying: Common Stock · 1,222 shares

Expires 2028-06-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F3 · derivative.exercise_date: The option began vesting monthly over 35 months beginning July 11, 2019, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-017915 · doc1.xml · nonDerivative · entry 1

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 178,622

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

SEC source: 0000947871-20-000782 · ownership.xml · nonDerivative · entry 2

ORBIMED ADVISORS LLC · CIK 0001055951 · Director · 10% owner

ORBIMED CAPITAL LLC · CIK 0001157524 · Director · 10% owner

OrbiMed Capital GP VII LLC · CIK 0001760648 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 902,286

F1 · shares: These shares of the Issuer's common stock ("Shares") were purchased in a private placement exempt from the registration requirements of the Securities Act of 1933, as amended.

F3 · ownership.nature: This report on Form 4 is filed by OrbiMed Advisors, OrbiMed GP VII, and OrbiMed Capital LLC ("OrbiMed Capital"). Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report on Form 4 shall not be deemed an admission that any of the Reporting Persons is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose. The Reporting Persons have designated Jonathan Silverstein to serve on the Issuer's board of directors.

F4 · ownership.nature: The Shares are held of record by OrbiMed Partners Master Fund Limited ("OPM"). OrbiMed Capital is the investment manager of OPM and is a relying advisor of OrbiMed Advisors. OrbiMed Advisors and OrbiMed Capital exercise voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and Jonathan T. Silverstein, each of whom disclaims beneficial ownership of the Shares held by OPM.

SEC source: 0000947871-20-000782 · ownership.xml · nonDerivative · entry 1

ORBIMED ADVISORS LLC · CIK 0001055951 · Director · 10% owner

ORBIMED CAPITAL LLC · CIK 0001157524 · Director · 10% owner

OrbiMed Capital GP VII LLC · CIK 0001760648 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,267,564

F1 · shares: These shares of the Issuer's common stock ("Shares") were purchased in a private placement exempt from the registration requirements of the Securities Act of 1933, as amended.

F2 · ownership.nature: The Shares are held of record by OrbiMed Private Investments VII, LP ("OPI VII"). OrbiMed Capital GP VII LLC ("OrbiMed GP VII") is the general partner of OPI VII and OrbiMed Advisors LLC ("OrbiMed Advisors") is the managing member of OrbiMed GP VII. OrbiMed GP VII and OrbiMed Advisors may be deemed to have voting and investment power over the securities held by OPI VII and may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and Jonathan T. Silverstein, each of whom disclaims beneficial ownership of the Shares held by OPI VII.

F3 · ownership.nature: This report on Form 4 is filed by OrbiMed Advisors, OrbiMed GP VII, and OrbiMed Capital LLC ("OrbiMed Capital"). Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. This report on Form 4 shall not be deemed an admission that any of the Reporting Persons is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose. The Reporting Persons have designated Jonathan Silverstein to serve on the Issuer's board of directors.

SEC source: 0000947871-20-000781 · ownership.xml · nonDerivative · entry 2

SILVERSTEIN JONATHAN · CIK 0001171005 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 902,286

F1 · shares: These shares of the Issuer's common stock ("Shares") were purchased in a private placement exempt from the registration requirements of the Securities Act of 1933, as amended.

F3 · ownership.nature: The Reporting Person is the designated representative of OrbiMed Advisors, OrbiMed GP VII, and OrbiMed Capital LLC ("OrbiMed Capital") on the Issuer's board of directors. Each of OrbiMed GP VII, OrbiMed Advisors, OrbiMed Capital LLC, and the Reporting Person disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its or his pecuniary interest therein, if any. This report on Form 4 shall not be deemed an admission that any such entity or person is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

F4 · ownership.nature: The Shares are held of record by OrbiMed Partners Master Fund Limited ("OPM"). OrbiMed Capital is the investment manager of OPM and is a relying adviser of OrbiMed Advisors. OrbiMed Advisors and OrbiMed Capital exercise voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and the Reporting Person, each of whom disclaims beneficial ownership of the Shares held by OPM.

SEC source: 0000947871-20-000781 · ownership.xml · nonDerivative · entry 1

SILVERSTEIN JONATHAN · CIK 0001171005 · Director · 10% owner

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 4,267,564

F1 · shares: These shares of the Issuer's common stock ("Shares") were purchased in a private placement exempt from the registration requirements of the Securities Act of 1933, as amended.

F2 · ownership.nature: The Shares are held of record by OrbiMed Private Investments VII, LP ("OPI VII"). OrbiMed Capital GP VII LLC ("OrbiMed GP VII"), is the general partner of OPI VII and OrbiMed Advisors LLC ("OrbiMed Advisors") is the managing member of OrbiMed GP VII. OrbiMed GP VII and OrbiMed Advisors may be deemed to have voting and investment power over the securities held by OPI VII and may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, Sven H. Borho, and the Reporting Person, each of whom disclaims beneficial ownership of the Shares held by OPI VII.

F3 · ownership.nature: The Reporting Person is the designated representative of OrbiMed Advisors, OrbiMed GP VII, and OrbiMed Capital LLC ("OrbiMed Capital") on the Issuer's board of directors. Each of OrbiMed GP VII, OrbiMed Advisors, OrbiMed Capital LLC, and the Reporting Person disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its or his pecuniary interest therein, if any. This report on Form 4 shall not be deemed an admission that any such entity or person is a beneficial owner of such securities for the purpose of Section 16 of the Exchange Act, or for any other purpose.

SEC source: 0001567619-20-017606 · doc1.xml · derivative · entry 7

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,448

Underlying: Common Stock · 390 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F4 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-017606 · doc1.xml · derivative · entry 6

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 34,581

Underlying: Common Stock · 1,810 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F4 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-017606 · doc1.xml · nonDerivative · entry 4

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 177,400

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · price: The transaction was executed in multiple trades in prices ranging from $27.68 to $28.46, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-017606 · doc1.xml · nonDerivative · entry 3

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 177,790

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-017606 · doc1.xml · nonDerivative · entry 2

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 177,400

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · price: The transaction was executed in multiple trades in prices ranging from $27.68 to $28.46, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-017606 · doc1.xml · nonDerivative · entry 1

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 179,210

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-017382 · doc1.xml · nonDerivative · entry 1

OSBORNE DAVID W · CIK 0001252999 · Chief Technical Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 264,279

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · balance_after: Includes 9,000 Restricted Stock Units ("RSUs"). The Reporting Person is entitled to receive one (1) share of common stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-20-017381 · doc1.xml · derivative · entry 4

Smither John W · CIK 0001559583 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 49,482

Underlying: Common Stock · 500 shares

Expires 2029-05-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F4 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-017381 · doc1.xml · nonDerivative · entry 3

Smither John W · CIK 0001559583 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Indirect · By Trust

Disclosed balance after: 98,715

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F3 · ownership.nature: The securities are held of record by The 1994 Smither Family Trust, as Amended and Restated in 2014, of which the Reporting Person is a trustee. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of such securities for purposes of Section 16 or for any other purposes.

SEC source: 0001567619-20-017381 · doc1.xml · nonDerivative · entry 2

Smither John W · CIK 0001559583 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 23,875

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · balance_after: Includes 9,000 Restricted Stock Units ("RSUs"). The Reporting Person is entitled to receive one (1) share of common stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-20-017381 · doc1.xml · nonDerivative · entry 1

Smither John W · CIK 0001559583 · Chief Financial Officer

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,375

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · balance_after: Includes 9,000 Restricted Stock Units ("RSUs"). The Reporting Person is entitled to receive one (1) share of common stock for each one (1) RSU upon the vesting thereof.

SEC source: 0001567619-20-017383 · doc1.xml · derivative · entry 7

Watanabe Todd Franklin · CIK 0001801061 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,492

Underlying: Common Stock · 3,000 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F6 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-017383 · doc1.xml · nonDerivative · entry 2

Watanabe Todd Franklin · CIK 0001801061 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 566,928

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-017383 · doc1.xml · nonDerivative · entry 1

Watanabe Todd Franklin · CIK 0001801061 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 569,928

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-21-000711 · doc1.xml · derivative · entry 7

Watanabe Todd Franklin · CIK 0001801061 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 155,492

Underlying: Common Stock · 3,000 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F6 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-21-000711 · doc1.xml · nonDerivative · entry 2

Watanabe Todd Franklin · CIK 0001801061 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 566,928

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-21-000711 · doc1.xml · nonDerivative · entry 1

Watanabe Todd Franklin · CIK 0001801061 · Director · President and CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 569,928

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-016809 · doc1.xml · derivative · entry 3

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 29,328

Underlying: Common Stock · 1,222 shares

Expires 2028-06-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F3 · derivative.exercise_date: The option began vesting monthly over 35 months beginning July 11, 2019, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-016809 · doc1.xml · nonDerivative · entry 1

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 177,400

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

SEC source: 0001567619-20-016301 · doc1.xml · derivative · entry 4

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,810

Underlying: Common Stock · 2,200 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F4 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-016301 · doc1.xml · nonDerivative · entry 2

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 176,178

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · price: The transaction was executed in multiple trades in prices ranging from $24.00 to $25.00, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-016301 · doc1.xml · nonDerivative · entry 1

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 178,378

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-017605 · doc1.xml · derivative · entry 7

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,838

Underlying: Common Stock · 1,172 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F4 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-017605 · doc1.xml · derivative · entry 6

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 36,391

Underlying: Common Stock · 1,028 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F4 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-017605 · doc1.xml · nonDerivative · entry 4

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 176,178

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · price: The transaction was executed in multiple trades in prices ranging from $24.00 to $25.00, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-017605 · doc1.xml · nonDerivative · entry 3

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 177,350

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-017605 · doc1.xml · nonDerivative · entry 2

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 176,178

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

F2 · price: The transaction was executed in multiple trades in prices ranging from $24.00 to $25.00, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

SEC source: 0001567619-20-017605 · doc1.xml · nonDerivative · entry 1

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 177,206

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Transaction made pursuant to a 10b5-1 trading plan adopted by the Reporting Person.

SEC source: 0001567619-20-015854 · doc1.xml · derivative · entry 3

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,982

Underlying: Common Stock · 5,000 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F3 · derivative.exercise_date: The option began vesting on March 13, 2019 and will vest monthly over a four year period, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.

SEC source: 0001567619-20-015854 · doc1.xml · nonDerivative · entry 1

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 176,178

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

SEC source: 0001567619-20-015772 · doc1.xml · derivative · entry 3

Welgus Howard G. · CIK 0001801050 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,667

Underlying: Common Stock · 5,076 shares

Expires 2029-03-13

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · kind: Reflects cash exercise of stock option without the disposition of the underlying shares.

F3 · derivative.exercise_date: The option began vesting monthly over a four year period beginning upon the achievement of certain company milestones, subject to the Reporting Person's continuous provision of services to the Issuer on each vesting date. The option contains an early-exercise provision and is exercisable as to unvested shares, subject to the Issuer's right of repurchase.