ACAD

SEC source: 0001209191-21-002831 · doc4.xml · nonDerivative · entry 6

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 46,492

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-21-002831 · doc4.xml · nonDerivative · entry 5

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 33,628

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-21-002831 · doc4.xml · nonDerivative · entry 4

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,247

F3 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 3, 2020.

SEC source: 0001209191-21-002831 · doc4.xml · nonDerivative · entry 3

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 81,866

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-21-002836 · doc4.xml · derivative · entry 3

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,167

Underlying: Common Stock · 2,722 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F4 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

F4 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

SEC source: 0001209191-21-002836 · doc4.xml · nonDerivative · entry 2

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 8,059

F2 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-21-002836 · doc4.xml · nonDerivative · entry 1

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,179

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-002834 · doc4.xml · derivative · entry 3

KIM AUSTIN D. · CIK 0001746240 · EVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,900

Underlying: Common Stock · 1,633 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F5 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

F5 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

SEC source: 0001209191-21-002834 · doc4.xml · nonDerivative · entry 2

KIM AUSTIN D. · CIK 0001746240 · EVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,518

F3 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-21-002834 · doc4.xml · nonDerivative · entry 1

KIM AUSTIN D. · CIK 0001746240 · EVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,196

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F2 · balance_after: Includes 712 shares of the Issuer's common stock acquired by the reporting person on November 13, 2020 pursuant to an employee stock purchase program.

SEC source: 0001209191-21-002832 · doc4.xml · derivative · entry 3

Ridloff Elena · CIK 0001772518 · EVP and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 9,873

Underlying: Common Stock · 1,016 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F3 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F4 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

F4 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

SEC source: 0001209191-21-002832 · doc4.xml · nonDerivative · entry 2

Ridloff Elena · CIK 0001772518 · EVP and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,901

F2 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-21-002832 · doc4.xml · nonDerivative · entry 1

Ridloff Elena · CIK 0001772518 · EVP and CFO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 4,917

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-002831 · doc4.xml · derivative · entry 10

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 69,631

Underlying: Common Stock · 61,619 shares

Expires 2027-09-06

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F7 · derivative.exercise_date: 25% of the shares subject to the Stock Option vested and became exercisable on September 7, 2018. The remaining shares vest and become exercisable thereafter in 36 equal monthly installments.

SEC source: 0001209191-21-002831 · doc4.xml · derivative · entry 9

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,333

Underlying: Common Stock · 5,444 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F6 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

F6 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

SEC source: 0001209191-21-002831 · doc4.xml · nonDerivative · entry 2

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 20,247

F2 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-21-002831 · doc4.xml · nonDerivative · entry 1

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 21,972

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-21-002830 · doc4.xml · derivative · entry 3

DAVIS STEPHEN · CIK 0001131146 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 28,583

Underlying: Common Stock · 9,527 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F5 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

F5 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning January 6, 2021.

SEC source: 0001209191-21-002830 · doc4.xml · nonDerivative · entry 2

DAVIS STEPHEN · CIK 0001131146 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 24,482

F3 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-21-002830 · doc4.xml · nonDerivative · entry 1

DAVIS STEPHEN · CIK 0001131146 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 27,966

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F2 · balance_after: Includes 3,653 shares of the Issuer's common stock acquired by the reporting person on November 13, 2020 pursuant to an employee stock purchase program.

SEC source: 0001209191-20-059854 · doc4.xml · nonDerivative · entry 2

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,528

F2 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-20-059854 · doc4.xml · derivative · entry 3

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,500

Underlying: Common Stock · 6,250 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning 11/19/2019.

F3 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning 11/19/2019.

SEC source: 0001209191-20-059854 · doc4.xml · nonDerivative · entry 1

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 19,256

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-20-056219 · doc4.xml · derivative · entry 3

KIM AUSTIN D. · CIK 0001746240 · EVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 113,750

Underlying: Common Stock · 8,750 shares

Expires 2028-07-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 25% of the shares subject to the Stock Option vested and became exercisable on July 18, 2019. The remaining shares vest and become exercisable thereafter in 36 equal monthly installments.

SEC source: 0001209191-20-056219 · doc4.xml · nonDerivative · entry 2

KIM AUSTIN D. · CIK 0001746240 · EVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,851

F2 · kind: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on 9/18/2020.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $45.00 to $45.525, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-20-056219 · doc4.xml · nonDerivative · entry 1

KIM AUSTIN D. · CIK 0001746240 · EVP & General Counsel

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,601

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · balance_after: Includes 1,410 shares of the Issuer's common stock acquired by the reporting person on May 15, 2020 pursuant to an employee stock purchase program.

SEC source: 0001209191-20-055317 · doc4.xml · nonDerivative · entry 2

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,457

F2 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-20-055316 · doc4.xml · nonDerivative · entry 2

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 13,006

F2 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-20-055315 · doc4.xml · nonDerivative · entry 2

DAVIS STEPHEN · CIK 0001131146 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,786

F2 · kind: The sales reported in this Form 4 were made to cover the tax obligation that occurred upon the vesting of restricted stock units.

SEC source: 0001209191-20-055317 · doc4.xml · derivative · entry 3

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,000

Underlying: Common Stock · 2,500 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning 10/15/19.

F3 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning 10/15/19.

SEC source: 0001209191-20-055317 · doc4.xml · nonDerivative · entry 1

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 7,704

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-20-055316 · doc4.xml · derivative · entry 3

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,938

Underlying: Common Stock · 2,969 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning 10/15/19.

F3 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning 10/15/19.

SEC source: 0001209191-20-055316 · doc4.xml · nonDerivative · entry 1

Stankovic Srdjan R. · CIK 0001432545 · President

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 14,303

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-20-055315 · doc4.xml · derivative · entry 3

DAVIS STEPHEN · CIK 0001131146 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 11,876

Underlying: Common Stock · 5,937 shares

Expires not disclosed

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

F3 · derivative.exercise_date: The restricted stock units vest in four equal annual installments beginning 10/15/19.

F3 · derivative.expiration_date: The restricted stock units vest in four equal annual installments beginning 10/15/19.

SEC source: 0001209191-20-055315 · doc4.xml · nonDerivative · entry 1

DAVIS STEPHEN · CIK 0001131146 · Director · CEO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,746

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F1 · price: Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock.

SEC source: 0001209191-20-052665 · doc4.xml · derivative · entry 2

GAROFALO ELIZABETH A. · CIK 0001826361 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,837

Underlying: Common Stock · 3,837 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of ACADIA common stock.

F3 · derivative.exercise_date: The restricted stock units shall vest in two equal annual installments commencing on the first anniversary of the grant date.

F3 · derivative.expiration_date: The restricted stock units shall vest in two equal annual installments commencing on the first anniversary of the grant date.

SEC source: 0001209191-20-052665 · doc4.xml · derivative · entry 1

GAROFALO ELIZABETH A. · CIK 0001826361 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 6,865

Underlying: Common Stock · 6,865 shares

Expires 2030-09-28

F1 · derivative.exercise_date: The shares subject to the stock option shall vest in two equal annual installments commencing on the first anniversary of the grant date.

SEC source: 0001209191-20-042022 · doc4.xml · derivative · entry 8

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 44,292

Underlying: Common Stock · 14,750 shares

Expires 2029-04-29

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F6 · derivative.exercise_date: 25% of the 59,042 shares originally subject to the Stock Option vested and became exercisable on April 29, 2020. The remaining shares vest and become exercisable thereafter in 36 equal monthly installments.

SEC source: 0001209191-20-042022 · doc4.xml · derivative · entry 7

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 25,000

Underlying: Common Stock · 5,000 shares

Expires 2028-10-14

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F5 · derivative.exercise_date: 25% of the 40,000 shares originally subject to the Stock Option vested and became exercisable on October 15, 2019. The remaining shares vest and become excercisable thereafter in 36 equal monthly installments.

SEC source: 0001209191-20-042022 · doc4.xml · derivative · entry 6

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 570,000

Underlying: Common Stock · 7,500 shares

Expires 2028-04-17

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

F4 · derivative.exercise_date: 25% of the 600,000 shares originally subject to the Stock Option vested and became exercisable on April 18, 2019. The remaining shares vest and become exercisable thereafter in 36 equal monthly installments

SEC source: 0001209191-20-042022 · doc4.xml · nonDerivative · entry 5

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,204

F1 · kind: The sales reported in this Form 4 were effected pursuant to an amended Rule 10b5-1 stock sale plan dated May 12, 2020.

F3 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $56.395 to $56.685, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-20-042022 · doc4.xml · nonDerivative · entry 4

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 16,304

F1 · kind: The sales reported in this Form 4 were effected pursuant to an amended Rule 10b5-1 stock sale plan dated May 12, 2020.

F2 · price: The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $55.39 to $56.39, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth above.

SEC source: 0001209191-20-042022 · doc4.xml · nonDerivative · entry 3

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 32,454

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-20-042022 · doc4.xml · nonDerivative · entry 2

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 17,704

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001209191-20-042022 · doc4.xml · nonDerivative · entry 1

YANG MICHAEL J. · CIK 0001702283 · EVP and CCO

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 12,704

Exercise/conversion can include RSU settlement. Transaction price and option strike are different fields; a missing price is not zero. Derivative and underlying rows can describe the same event.

SEC source: 0001638599-20-000636 · doc4_6779.xml · derivative · entry 5

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 11,158

Underlying: Common Stock · 11,158 shares

Expires 2030-06-23

F10 · derivative.exercise_date: 5,579 Stock Options exercisable solely into Common Stock were granted under the Incentive Plan to each of Julian C. Baker and Dr. Biggar in their capacity as directors of the Issuer. The Stock Options with a strike price of $52.73 vest in 4 equal quarterly installments beginning on June 23, 2020 and expire on June 23, 2030.

F4 · ownership.nature: Julian C. Baker and Dr. Biggar serve on the board of directors of the Issuer (the "Board") as representatives of Baker Brothers Life Sciences, L.P. ("Life Sciences") and 667, L.P. ("667", and together with Life Sciences, the "Funds"). Pursuant to the policies of the Adviser, Julian C. Baker and Dr. Biggar do not have any right to any of the Issuer's securities issued as part of their service on the Board and the Funds are entitled to receive all of the pecuniary interest in the securities issued. The Funds each own an indirect proportionate pecuniary interest in the RSU's and non-qualified options to purchase Common Stock ("Stock Options").

F5 · ownership.nature: Solely as a result of Felix J. Baker's and Julian C. Baker's ownership interest in (i) the general partners of the Funds and (ii) the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the RSU's, Stock Options, Common Stock received upon vesting of RSU's and Common Stock received upon exercise of Stock Option (i.e. no direct pecuniary interest).

F8 · ownership.nature: The Adviser serves as the investment adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. The Adviser GP is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are managing members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. The Adviser has voting and dispositive power over the Stock Options, RSU's and any Common Stock received as a result of the exercise of Stock Options or vesting of RSU's.

F9 · ownership.nature: Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

F10 · ownership.nature: 5,579 Stock Options exercisable solely into Common Stock were granted under the Incentive Plan to each of Julian C. Baker and Dr. Biggar in their capacity as directors of the Issuer. The Stock Options with a strike price of $52.73 vest in 4 equal quarterly installments beginning on June 23, 2020 and expire on June 23, 2030.

SEC source: 0001638599-20-000636 · doc4_6779.xml · nonDerivative · entry 4

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 38,440,095

F3 · ownership.nature: Restricted Stock Units (each an "RSU") payable solely in Common Stock granted to each of Julian C. Baker, a managing member of Baker Bros. Advisors (GP) LLC (the "Adviser GP") and Dr. Stephen R. Biggar, a full-time employee of Baker Bros. Advisors LP (the "Adviser") on June 23, 2020, pursuant to the Issuer's 2010 Equity Incentive Plan ("Incentive Plan"). The RSUs fully vest on the earlier of June 23, 2021 or the date of the next annual meeting of the Issuer.

F4 · ownership.nature: Julian C. Baker and Dr. Biggar serve on the board of directors of the Issuer (the "Board") as representatives of Baker Brothers Life Sciences, L.P. ("Life Sciences") and 667, L.P. ("667", and together with Life Sciences, the "Funds"). Pursuant to the policies of the Adviser, Julian C. Baker and Dr. Biggar do not have any right to any of the Issuer's securities issued as part of their service on the Board and the Funds are entitled to receive all of the pecuniary interest in the securities issued. The Funds each own an indirect proportionate pecuniary interest in the RSU's and non-qualified options to purchase Common Stock ("Stock Options").

F5 · ownership.nature: Solely as a result of Felix J. Baker's and Julian C. Baker's ownership interest in (i) the general partners of the Funds and (ii) the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the RSU's, Stock Options, Common Stock received upon vesting of RSU's and Common Stock received upon exercise of Stock Option (i.e. no direct pecuniary interest).

F7 · ownership.nature: After giving effect to the transaction reported herein and as a result of their ownership interest in (i) Baker Brothers Life Sciences Capital, L.P. and (ii) Life Sciences, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in Common Stock of the Issuer reported in column 5 of Table I directly held by Life Sciences, a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to their interest in Life Sciences and Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences.

F8 · ownership.nature: The Adviser serves as the investment adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. The Adviser GP is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are managing members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. The Adviser has voting and dispositive power over the Stock Options, RSU's and any Common Stock received as a result of the exercise of Stock Options or vesting of RSU's.

F9 · ownership.nature: Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

F11 · ownership.nature: The disclosure of the grant of RSU's reported on this form is the sum of two grants totaling 6,118 shares. The 6,118 shares are reported for each of the Funds as each has an indirect pecuniary interest.

SEC source: 0001638599-20-000636 · doc4_6779.xml · nonDerivative · entry 3

BAKER BROS. ADVISORS LP · CIK 0001263508 · Director · 10% owner

667, L.P. · CIK 0001551139 · Director · 10% owner

Baker Bros. Advisors (GP) LLC · CIK 0001580575 · Director · 10% owner

Baker Brothers Life Sciences LP · CIK 0001363364 · Director · 10% owner

BAKER FELIX · CIK 0001087940 · Director · 10% owner

BAKER JULIAN · CIK 0001087939 · Director · 10% owner

Joint disclosure: these amounts are not allocated separately to each reporting owner.

10b5-1 filing: Not disclosed

Ownership: Indirect · See Footnotes

Disclosed balance after: 3,476,727

F3 · ownership.nature: Restricted Stock Units (each an "RSU") payable solely in Common Stock granted to each of Julian C. Baker, a managing member of Baker Bros. Advisors (GP) LLC (the "Adviser GP") and Dr. Stephen R. Biggar, a full-time employee of Baker Bros. Advisors LP (the "Adviser") on June 23, 2020, pursuant to the Issuer's 2010 Equity Incentive Plan ("Incentive Plan"). The RSUs fully vest on the earlier of June 23, 2021 or the date of the next annual meeting of the Issuer.

F4 · ownership.nature: Julian C. Baker and Dr. Biggar serve on the board of directors of the Issuer (the "Board") as representatives of Baker Brothers Life Sciences, L.P. ("Life Sciences") and 667, L.P. ("667", and together with Life Sciences, the "Funds"). Pursuant to the policies of the Adviser, Julian C. Baker and Dr. Biggar do not have any right to any of the Issuer's securities issued as part of their service on the Board and the Funds are entitled to receive all of the pecuniary interest in the securities issued. The Funds each own an indirect proportionate pecuniary interest in the RSU's and non-qualified options to purchase Common Stock ("Stock Options").

F5 · ownership.nature: Solely as a result of Felix J. Baker's and Julian C. Baker's ownership interest in (i) the general partners of the Funds and (ii) the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the RSU's, Stock Options, Common Stock received upon vesting of RSU's and Common Stock received upon exercise of Stock Option (i.e. no direct pecuniary interest).

F6 · ownership.nature: After giving effect to the transaction reported herein and as a result of their ownership interest in (i) Baker Biotech Capital, L.P. and (ii) 667, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in Common Stock reported in column 5 of Table I directly held by 667, a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP), LLC, due to their interest in 667 and Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667.

F8 · ownership.nature: The Adviser serves as the investment adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. The Adviser GP is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are managing members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. The Adviser has voting and dispositive power over the Stock Options, RSU's and any Common Stock received as a result of the exercise of Stock Options or vesting of RSU's.

F9 · ownership.nature: Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

F11 · ownership.nature: The disclosure of the grant of RSU's reported on this form is the sum of two grants totaling 6,118 shares. The 6,118 shares are reported for each of the Funds as each has an indirect pecuniary interest.

SEC source: 0001209191-20-038979 · doc4.xml · derivative · entry 2

SOLAND DANIEL B · CIK 0001318485 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 3,059

Underlying: Common Stock · 3,059 shares

Expires not disclosed

F2 · derivative.exercise_price: Each restricted stock unit represents a contingent right to receive one share of ACADIA common stock.

F3 · derivative.exercise_date: The restricted stock units shall vest in full upon the earlier of one year following the date of grant or the next annual meeting date.

F3 · derivative.expiration_date: The restricted stock units shall vest in full upon the earlier of one year following the date of grant or the next annual meeting date.

SEC source: 0001209191-20-038979 · doc4.xml · derivative · entry 1

SOLAND DANIEL B · CIK 0001318485 · Director

10b5-1 filing: Not disclosed

Ownership: Direct

Disclosed balance after: 5,579

Underlying: Common Stock · 5,579 shares

Expires 2030-06-22

F1 · derivative.exercise_date: The shares subject to the option shall vest quarterly over one year following the date of grant, with the final tranche vesting upon the earlier of one year following the date of grant or the next annual meeting date.